• 제목/요약/키워드: Negative g

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젖소 유방유래(乳房由來) 난포구원(蘭葡球園)에 관한 연구(硏究) : III. 분리균주(分離菌株)에 대한 Penicillins 및 Gentamicin의 항균효과(抗菌效果) (Studies on Staphylococci Isolated from Bovine Mastitis: III. Activity of Penicillins and Gentamicin to Isolates)

  • 박청규
    • 대한수의학회지
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    • 제24권2호
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    • pp.163-168
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    • 1984
  • The in vitro activity of penicillins(penicillin G, ampicillin, carbenicillin, methicillin and cloxacillin) and gentamicin to Staphylococcus aureus and coagulase-negative staphylococci isolated from bovine mastitic milk samples was determined. The growth of all isolates of staphylococci tested was inhibited by cloxacillin and methicillin at a concentration of $0.78{\mu}g/ml$ and by gentamicin at a minimum inhibitory concentration (MIC) of $1.56{\mu}g/ml$. Of the 140 strains of Staphylococcus aureus isolated 99(70.7%) gave positive reactions for penicillinase on the starch-iodine test. Of 121 isolates of coagulase-negative staphylococci, 58(47.9%) showed penicillinase production, but all the Staph. xylosus lacked the ability to produce penicillinase. MIC of penicillin G of the penicillinase-positive strains was $0.2{\mu}g/ml$ or more. The combination of cloxacillin with gentamicin showed a synergistic effect by inhibiting regrowth of the tested organism.

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포텐셜필드의 스텍트럼대비법을 이용한 의성소분지의 지구조 연구 (Geologic Structure of Euiseong Sub-basin from Spectrally Correlated Geopotential Field Anomalies)

  • 김원균
    • 자원환경지질
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    • 제33권3호
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    • pp.217-228
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    • 2000
  • We use spectral correlation method to analyze gravity and magnetic anomalies of Euiseong Sub-basin for distribution of rock facies and gelogic structures. The analysis reveals distinct polarity between gravity and magnetic anomaly correlation ; intermediate to mafic intrusives, extrusives, and the Tertiary basin shows positive gravity (+G) and positive magnetic (+M) correlation. Granitic gneiss and felsic volcanics negative gravity 9-G) and negative magnetic (-M) correlation. The Palgongsan granite, felsic to mafic extrusives and Mesozoic granites are characterized by -G and + M correlation. +G and -M correlations in the sedimentary formations are interpreted by uplift of pre-Cretaceous basement rocks . The + G and + M correlation characteristics in northeastern part of Euiseong Sub-basin including the Tertiary sedimentary basin result from the uplift of crustal materials. Major axes of spectrally correlated amomalies have mostly NW-SE or NE-SW directions. The former is due to the intrusives along strike-slip faults, and the latter which is observed in sedimentary formations is related to geological structures of basement associated new insight into the boundary between Euiseong and Milyang Sub-basin.

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Serum 8 Hydroxydeoxyguanosine and Cytotoxin Associated Gene A as Markers for Helicobacter pylori Infection

  • Yeniova, Abdullah Ozgur;Uzman, Metin;Kefeli, Ayse;Basyigit, Sebahat;Ata, Naim;Dal, Kursat;Guresci, Servet;Nazligul, Yasar
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권13호
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    • pp.5199-5203
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    • 2015
  • Background: Helicobacter pylori (H.pylori) is associated with chronic gastritis, peptic ulcers, gastric adenocarcinomas and mucosa associated tissue lymphomas. Cytotoxin associated gene A (CagA) is one of the virulence factors of H.pylori. It is hypothesized that reactive oxygen species (ROS) play roles in H.pylori associated disease especially in development of gastric adenocarcinoma. Individuals infected with H.pylori bearing CagA produce more ROS than others. 8-hydroxydeoxyguanosine (8OHdG) is an in vitro marker of DNA damage and oxidative stress. The aim of this study was to investigate the relationship between 8OHdG level, H.pylori infection and CagA and alterations of serum 8OHdG level after H.pylori eradication. Materials and Methods: Patients admitted with dyspeptic complaints and upper gastrointestinal endoscopy were assessed. H.pylori was determined from histopathology of specimens. Serum 8OHdG levels of three groups (H.pylori negative, H. pylori positive CagA negative and H.pylori positive CagA positive) were compared. Patients with H.pylori infection received eradication therapy. Serum 8OHdG levels pretreatment and posttreatment were also compared. Results: In total, 129 patients (M/F, 57/72) were enrolled in the study. Serum 8OHdG level of H.pylori negative, H. pylori positive CagA negative and H.pylori positive CagA positive groups were significantly different ($5.77{\pm}1.35ng/ml$, $5.43{\pm}1.14ng/ml$ and $7.57{\pm}1.25ng/ml$ respectively, p=0.05). Furthermore, eradication therapy reduced serum 8OHdG level ($6.10{\pm}1.54ng/ml$ vs $5.55{\pm}1.23ng/ml$, p=0.05). Conclusions: Individuals infected with H.pylori bearing CagA strains have the highest serum 8OHdG level and eradication therapy decreases the serum 8OHdG level. To the best of our knowledge this is the first study that evaluated the effect of CagA virulence factor on serum 8OHdG level and the effect of eradication therapy on serum 8OHdG levels together. Eradication of CagA bearing H.pylori may prevent gastric adenocarcinoma by decreasing ROS. 8OHdG level may thus be a good marker for prevention from gastric adenocarcinoma.

Evaluation of Antimicrobial Activity of the Methanol Extracts from 8 Traditional Medicinal Plants

  • Kang, Chang-Geun;Hah, Dae-Sik;Kim, Chung-Hui;Kim, Young-Hwan;Kim, Eui-Kyung;Kim, Jong-Shu
    • Toxicological Research
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    • 제27권1호
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    • pp.31-36
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    • 2011
  • The methanol extract of 12 medicinal plants were evaluated for its antibacterial activity against Gram-positive (5 strains) and Gram-negative bacteria (10 strains) by assay for minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC). The antibacterial activity was determined by an agar dilution method (according to the guidelines of Clinical and Laboratory Standard Institute). All the compounds (12 extracts) of the 8 medicinal plants (leaf or root) were active against both Gram-negative and Gram-positive bacteria. Gram-negative showed a more potent action than Gram positive bacteria. The MIC concentrations were various ranged from $0.6\;{\mu}g/ml$ to $5000\;{\mu}g/ml$. The lowest MIC ($0.6\;{\mu}g/ml$) and MBC ($1.22\;{\mu}g/ml$) values were obtained with extract on 4 and 3 of the 15 microorganisms tested, respectively.

원유시료에서 분리된 반코마이신 저항성 Coagulase-Negative Staphylococcus 균주의 특성 (Characterization of a Coagulase-Negative Staphylococcus sp. Isolated from Raw-Milk having Reduced Susceptibility to Vancomycin)

  • 하남주;최성숙
    • 약학회지
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    • 제45권5호
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    • pp.491-493
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    • 2001
  • Coagulase-negative Staphylococcus sp #39, isolated from raw-milk showed reduced susceptibility to vancomycin. The minimun inhibitory concentration for strain #39 was at 8$\mu\textrm{g}$ of vancomycin per ml. Transmitting electron microscopy displayed that this strain had a 2.5-3.5 times thicker cell wall than a vancomucin sensitive strain of Staphylococcus sp. The strain #39 also had an increased cell volume. These data indicate that the reduced susceptibility may be due to the thickness of the cell wall of the test strain.

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Antimicrobial Activity of Oleanolic Acid, Ursolic Acid, and Sophoraflavanone G against Periodontopathogens

  • Park, Soon-Nang;Kook, Joong-Ki
    • International Journal of Oral Biology
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    • 제38권4호
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    • pp.149-154
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    • 2013
  • In general, oleanolic acid (OA) and ursolic acid (UA) have antimicrobial effect against Gram-positive bacteria but not Gram-negative bacteria whereas sophoraflavanone G has antimicrobial activity against both bacterial types. However, the antimicrobial effects of OA, UA, and sophoraflavanone G against periodontopathogens have not been studied to any great extent. The aim of this study was to investigate antimicrobial effect of OA, UA, and sophoraflavanone G against 15 strains (5 species) of oral Gram-negative bacteria, which are the major causative bacteria of periodontal disease. The antimicrobial activity was evaluated by minimal inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) determinations. OA and UA showed antimicrobial effects against all of the Porphyromonas gingivalis strains tested and also Prevotella intermedia ATCC $25611^T$. Interestingly, P. intermedia ATCC 49046 showed greater resistance to OA and UA than P. intermedia ATCC $25611^T$. In contrast, sophoraflavanone G had antimicrobial activity against all strains, with MIC and MBC values below $32{\mu}g/ml$, except Aggregatibacter actinomycetemcomitans. These results indicate that sophoraflavanone G may have potential for use in future oral hygiene products such as dentifrices and gargling solution to prevent periodontitis.

5G 시스템에서 상관 정보원의 비직교 다중접속을 위한 음수의 상관관계 계수 B2S 사상 (On Negative Correlation Bit-to-Symbol(: B2S) Mapping for NOMA with Correlated Information Sources in 5G Systems)

  • 정규혁
    • 한국전자통신학회논문지
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    • 제15권5호
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    • pp.881-888
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    • 2020
  • 본 논문에서는, 상호작용 이동통신 사용자의 비직교 다중접속에서 강채널 사용자의 저하된 BER 성능을 향상하기 위해 음수의 상관관계 계수 B2S 사상을 제안한다. 먼저, 음수의 상관관계 계수 B2S 사상 수신기의 BER의 폐쇄형 표현식을 유도하고, 이상적인 완벽한 SIC 수신기와 양수의 상관관계 계수 수신기의 BER과 비교하여, B2S 수신기의 BER이 향상되었음을 보여준다. 또한, 이론적인 분석에 기초하여 SNR 이득을 구하여 음수의 상관관계 계수 B2S 사상 수신기의 성능 우수성을 입증한다.

유튜브 댓글을 통해 살펴본 버추얼 인플루언서에 대한 인식 연구 -캐릭터 디자인에 대한 긍부정 감성 반응을 중심으로- (A Study on Perceptions of Virtual Influencers through YouTube Comments -Focusing on Positive and Negative Emotional Responses Toward Character Design-)

  • 안효선;김지영
    • 한국의류학회지
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    • 제47권5호
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    • pp.873-890
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    • 2023
  • This study analyzed users' emotional responses to VI character design through YouTube comments. The researchers applied text-mining to analyze 116,375 comments, focusing on terms related to character design and characteristics of VI. Using the BERT model in sentiment analysis, we classified comments into extremely negative, negative, neutral, positive, or extremely positive sentiments. Next, we conducted a co-occurrence frequency analysis on comments with extremely negative and extremely positive responses to examine the semantic relationships between character design and emotional characteristic terms. We also performed a content analysis of comments about Miquela and Shudu to analyze the perception differences regarding the two character designs. The results indicate that form elements (e.g., voice, face, and skin) and behavioral elements (e.g., speaking, interviewing, and reacting) are vital in eliciting users' emotional responses. Notably, in the negative responses, users focused on the humanization aspect of voice and the authenticity aspect of behavior in speaking, interviewing, and reacting. Furthermore, we found differences in the character design elements and characteristics that users expect based on the VI's field of activity. As a result, this study suggests applications to character design to accommodate these variations.

Impacts of Soil Texture on Microbial Community of Orchard Soils in Gyeongnam Province

  • Kim, Min Keun;Sonn, Yeon-Kyu;Weon, Hang-Yeon;Heo, Jae-Young;Jeong, Jeong-Seok;Choi, Yong-Jo;Lee, Sang-Dae;Shin, Hyun-Yul;Ok, Yong Sik;Lee, Young Han
    • 한국토양비료학회지
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    • 제48권2호
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    • pp.81-86
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    • 2015
  • Soil management for orchard depends on the effects of soil microbial activities. The present study evaluated the soil microbial community of 25 orchard (5 sites for sandy loam, 7 sites for silt loam, and 13 sites for loam) in Gyeongnam Province by fatty acid methyl ester (FAME) method. The average values for 25 orchard soil samples were $270nmol\;g^{-1}$ of total FAMEs, $72nmol\;g^{-1}$ of total bacteria, $34nmol\;g^{-1}$ of Gram-negative bacteria, $34nmol\;g^{-1}$ of Gram-positive bacteria, $6nmol\;g^{-1}$ of actinomycetes, $49nmol\;g^{-1}$ of fungi, and $7nmol\;g^{-1}$ of arbuscular mycorrhizal fungi. In addition, silt loam soils had significantly low ratio of cy17:0 to $16:1{\omega}7c$ and cy19:0 to $18:1{\omega}7c$ compared with those of loam soils (p < 0.05), indicating that microbial activity increased. The average soil microbial communities in the orchard soils were 26.7% of bacteria, 17.9% of fungi, 12.6% of Gram-negative bacteria, 12.5% of Gram-positive bacteria, 2.5% of arbuscular mycorrhizal fungi, and 2.2% of actinomycetes. The soil microbial community of Gram-negative bacteria in silt loam soils was significantly higher than those of sandy loam and loam soils (p < 0.05).

성인여성의 의복가치관과 화장행동에 관한 연구 (A Study of Clothing Value and Make-up Behavior of Women)

  • 최수경;강경자
    • 한국생활과학회지
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    • 제16권2호
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    • pp.395-405
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    • 2007
  • The women selected by random sampling were classified into four groups by their body cathexis and Make-up attitude in order to investigate differences in Clothing Value and Make-up behavior. The result are as follows. Cluster was classified into four groups: positive congruity(G1), positive incongruity(G2), negative congruity(G3), negative incongruity(G4). Four groups showed meaningful difference each other between the peculiarity of Clothing value and Make-up behavior. Make-up behaviors were different at the peculiarity of minutely divided groups under the standard of physical satisfaction and Make-up attitude, and they showed difference in the influence of value affected to each behavior. So it was testified that Make-up behavior can be different depending on the value of respective persons.