• 제목/요약/키워드: Negative conversion

검색결과 327건 처리시간 0.032초

포스트 코로나 시대 신종 감염병 대비를 위한 기존 의료시설의 비상시 운영사례 조사 및 분석 (Investigations on the emergency operation status of existing medical facilities to prepare for emerging infectious diseases in the post-COVID-19 era)

  • 이세진;이원석;김은석;여명석
    • 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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    • 제29권1호
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    • pp.43-51
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    • 2023
  • Purpose: To accommodate the increasing number of patients during the COVID-19 pandemic, numerous portable HEPA filter units (PHUs) were installed in the general wards of existing medical facilities(EMFs) to convert them into emergency conversion facilities (ECFs). The purpose of this study was to build a dataset in preparation for emerging infectious diseases in the post-COVID-19 era by analyzing the construction and operation of ECFs. Methods: Field investigations were conducted during ECF operation periods based on the analysis of heating, ventilation, and air conditioning (HAVC) system design documents for six ECFs across Korea. Interviews were conducted with facility managers during the field investigations. Results: When constructing an ECF within an EMF, the installation status and characteristics of the existing system should be considered. Field investigations and verifications of the operation of HAVC systems must be conducted beforehand for smooth ECF operations. If heating and cooling are required with indoor air circulation type equipment in an ECF zone, the implementation of a heating and cooling method that can satisfy the comfort requirements of the occupants while minimizing cross-contamination is essential. When using PHUs that do not meet the performance standards required by medical equipment, the noise level resulting from such equipment operation must be evaluated and improved. Implications: For EMFs, various guidelines that can be referred to for the construction and operation of ECFs must be developed to prepare for emerging infectious diseases in the future.

디지털 혁신이 기업 재무활동에 미치는 영향: 녹색기술혁신의 매개효과 (The Impact of Digital Transformation on Business Financialization: Mediating Effect of Green Technology Innovation)

  • 김경일
    • 산업과 과학
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    • 제2권4호
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    • pp.17-27
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    • 2023
  • 본 연구는 국내 중소제조업체들이 디지털 전환을 시도할 때 고려하여야 할 요인을 제시하여 디지털 전환의 효율성을 향상시킬 수 있도록 함에 연구의 목적이 있다. 2019년부터 2021년까지의 중소기업 데이터를 활용하여 디지털 전환이 기업의 재무활동에 미치는 영향과 어떠한 디지털 기술이 재무활동에 영향을 미치는지 분석하고 디지털 전환과 기업 재무활동 사이의 녹색 기술 혁신의 매개 효과에 대해 추가적으로 분석하였다. 연구결과 디지털 기술이 기업 재무활동에 미치는 부정적인 영향을 뒷받침하고 있으며 클라우드 컴퓨팅 기술은 기업 재무활동 수준을 상당히 억제하는 것으로 밝혀졌다. 또한 녹색기술혁신은 디지털 전환이 녹색기술혁신을 촉진하여 기업의 재무활동을 억제하는 매개역할을 하는 것으로 나타났다. 디지털 전환은 녹색 기술 혁신을 통해 기업 의사결정에 영향을 미치며 디지털 기술과 녹색 프로젝트의 결합을 고려해야 할 것을 제언한다.

폐결핵 재치료의 Prothionamide, Cycloserine, Para-Aminosalicylic Acid, Streptomycin (Kanamycin or Tuberactinomycin) 4제 요법 임상 효과 (A Clinical Effect of Retreatment by Prothionamide, Cycloserine, Para-Aminosalicylic Acid, Streptomycin (Kanamycin or Tuberactinomycin) on Pulmonary Tuberculosis)

  • 신철식;임영재;김영준;고석신;김문식
    • Tuberculosis and Respiratory Diseases
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    • 제39권2호
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    • pp.167-171
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    • 1992
  • PTA, CS, PAS, SM (KM 또는 TUM) 4제 요법의 임상효과를 알고자 지난 5년동안 국립 공주 병원에 입원하였던 도말양성 환자중 추적 가능한 112명을 대상으로 한 조사에서 다음과 같은 결과를 얻었다. 균 도말검사상 64%가 음전을 나타내었고 그 시기는 85%가 3개월 이내에 이루어졌다. 방사선 소견은 반응이 없는 경우가 약 반 정도이었으며, 세균학적 검사를 함께 고려하여 판단할 때 62% 정도만이 양호한 결과를 나타내었다. 양호한 결과는 병력이 짧고 내성정도가 적을수록 좋았다. 그리고 병력이 오래된 환자의 재치료 처방은 적어도 3제 이상의 감수성을 가진 약제를 선택해야 되며, 두가지 이하의 감수성이 있는 경우는 INH 단독 요법등의 고려가 필요할 것으로 사료된다.

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Duration of Pulmonary Tuberculosis Infectiousness under Adequate Therapy, as Assessed Using Induced Sputum Samples

  • Ko, Yousang;Shin, Jeong Hwan;Lee, Hyun-Kyung;Lee, Young Seok;Lee, Suh-Young;Park, So Young;Mo, Eun-Kyung;Kim, Changhwan;Park, Yong Bum
    • Tuberculosis and Respiratory Diseases
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    • 제80권1호
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    • pp.27-34
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    • 2017
  • Background: A sputum culture is the most reliable indicator of the infectiousness of pulmonary tuberculosis (PTB); however, a spontaneous sputum specimen may not be suitable. The aim of this study was to evaluate the infectious period in patients with non-drug-resistant (DR) PTB receiving adequate standard chemotherapy, using induced sputum (IS) specimens. Methods: We evaluated the duration of infectiousness of PTB using a retrospective cohort design. Results: Among the 35 patients with PTB, 22 were smear-positive. The rates of IS culture positivity from baseline to the sixth week of anti-tuberculosis medication in the smear-positive PTB group were 100%, 100%, 91%, 73%, 36%, and 18%, respectively. For smear-positive PTB cases, the median time of conversion to culture negativity was 35.0 days (range, 28.0-42.0 days). In the smear-negative PTB group (n=13), the weekly rates of positive IS culture were 100%, 77%, 39%, 8%, 0%, and 0%, respectively, and the median time to conversion to culture-negative was 21.0 days (range, 17.5-28.0 days). Conclusion: The infectiousness of PTB, under adequate therapy, may persist longer than previously reported, even in patients with non-DR PTB.

경상남도 산청군 주민의 간흡충 감염 상황변화 (Current status and the changing pattern of the prevalence of clonorchiasis in the inhabitants in Sanchong-gun, Kyongsangnam-do, Korea)

  • 이종수;이원자
    • Parasites, Hosts and Diseases
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    • 제31권3호
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    • pp.207-214
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    • 1993
  • 경상남도 산청군 주민의 간흡충 감염 현황을 파악하고 1984년 조사자료와 비교 평가하기 위하여 1992년 10월에 역학조사를 하였다. 일반 주민의 간흘충 충란양성률은 837명에 대한 조사에서 37.6%(남자 48.1%. 여자 28.6%)였다. 국민학생은 145명중 평균 9.7%(남자 9.9%, 여자 9.4%)를 보였다. 일반주민의 EPG(599 Per gram offices) 평균치는 3.310(남자 4.221 여자 1.978)이었다. 국민학생은 711(남자 620. 여자 833)을 보였으며 20대에서 7.852로 가장 높았다 EPG에 따는 감염자의 분포는 72.6%가 1,000미만의 경감염자이었고 10.000미만의 중등도까지 93 9%가 포함되었다. 중감염자로는 EPG 120.000이상에 속하는 사람이 0.3%를 차지했다. 감염자의 민물고기 생식 경험률은 90.5%. 최근 2년내 생식한 사람은 71.1%였다. 1984년과 1992년에 조사된 동일인 138명 중 반복감염자가 31명(22.5%). 음성으로 전환된 자가 35명(25.4%), 새로 양성 전환자가 22명(15.9%)이었다. 그러므로 1984년 자료와 비교할때 충란양성률은 국민학생은 줄고 일반 주민은 변화가 없었으며. 감염강도는 주민과 국민학생 모두에게서 감소하였고, 주민의 민물고기 생식습관은 변하지 않았음을 알 수 있었다. 이 지역에서는 주민들의 식습관의 변화가 앞으로 간흡충 퇴치사업에 가장 중요한 요인이다.

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노인운동의 변화단계에 따른 변화과정에 관한 연구 (Process of Change Corresponding to the Stage of Change of Exercise in Elderly)

  • 전영자;김소인;이평숙;김순용;이숙자;박은숙;장성옥
    • 대한간호학회지
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    • 제30권2호
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    • pp.354-365
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    • 2000
  • Purpose: This study was performed to identify the factors that change exercise behave. This study will also classify and identify the characteristics of excercise stages to which the elderly belong Also, to identify the processes of change which influence on the changes in exercise performed by the elderly. Methods: Convenient samples of 198 subjects over the age 60 in Seoul Korea(mean age=70) were selected from elderly communities and were all mentally conpetant older adults. The data were collected from April 1,1999 to May 30, 1999. The research instruments were measured the change in exercise (Marcus et al., 1992b), such as Stage of Change measure(Marcus et al,1992a). The data were analyzed by SAS Program. Results: 1. According to the measure of change without missing data, 191 subjects were distributed each stage of change for exercise: 50 subjects (26.1%), 7 subjects (3.6%), 52 subjects (27.2%), 4 subjects (2%), and 78 (40.8%) belonged to the precontemplation stage, the contemplation stage, the preparation stage, the action stage and the maintenace stage. 2. According to the factor analysis, 6 factors of change were identified as appropriate processes of change and were named by the researchers. The names were; 'Supportive helping relationship', 'Self cognitive determination', 'Environmental reinforcement', Consciousness raising', Reinforcement of negative condition and 'Conversion of negative condition'. 3. According to the stage of change, there were significant mean differences in the 'Supportive helping relationship(F=22.04, p=.0001)', 'Self cognitive determination (F=50.87, p=.0001)', 'Reinforcement of negative condition(F=7.84,p=.0006)'. 4. Through the discriminant analysis, it was found that Self cognitive determination is the most influential variable as one of the processes of change which can discrimiate the three stages of change (precontemplation, preparation, and maintenance). Also the next significant variable was Reinforcement of negative condition. Conclusion: The process of the dey change is one of concepts of The transtheoretical model known as strategies and the techniques people use as they go through the different stages of change. Even though this study is cross- sectional not longitudinal study, the finding of this study gives useful information for exercise intervention, by using this strategy of exercise for elderly in different stages of change in exercise.

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Selection and Characterization of Staphylococcus hominis subsp. hominis WiKim0113 Isolated from Kimchi as a Starter Culture for the Production of Natural Pre-converted Nitrite

  • Hwang, Hyelyeon;Lee, Ho Jae;Lee, Mi-Ai;Sohn, Hyejin;Chang, You Hyun;Han, Sung Gu;Jeong, Jong Youn;Lee, Sung Ho;Hong, Sung Wook
    • 한국축산식품학회지
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    • 제40권4호
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    • pp.512-526
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    • 2020
  • Synthetic nitrite is considered an undesirable preservative for meat products; thus, controlling synthetic nitrite concentrations is important from the standpoint of food safety. We investigated 1,000 species of microorganisms from various kimchi preparations for their potential use as a starter culture for the production of nitrites. We used 16S rRNA gene sequence analysis to select a starter culture with excellent nitrite and nitric oxide productivity, which we subsequently identified as Staphylococcus hominis subspecies hominis WiKim0113. That starter culture was grown in NaCl (up to 9%; w/v) at 10℃-40℃; its optimum growth was observed at 30℃ at pH 4.0-10.0. It exhibited nonproteolytic activity and antibacterial activity against Clostridium perfringens, a bacterium that causes food poisoning symptoms. Analysis of Staphylococcus hominis subspecies hominis WiKim0113 with an API ZYM system did not reveal the presence of β-glucuronidase, and tests of the starter culture on 5% (v/v) sheep blood agar showed no hemolytic activity. Our results demonstrated the remarkable stability of coagulase-negative Staphylococcus hominis subspecies hominis WiKim0113, especially in strain negative for staphylococcal enterotoxins and sensitive to clinically relevant antibiotics. Moreover, Staphylococcus hominis subspecies hominis WiKim0113 exhibited a 45.5% conversion rate of nitrate to nitrite, with nitrate levels reduced to 25% after 36 h of culturing in the minimal medium supplemented with nitrate (200 ppm). The results clearly demonstrated the safety and utility of Staphylococcus hominis subspecies hominis WiKim0113, and therefore its suitability as a starter culture.

입자크기 분포를 고려한 부력침강 저수지 밀도류의 탁도 모델링 (Turbidity Modeling for a Negative Buoyant Density Flow in a Reservoir with Consideration of Multiple Particle Sizes)

  • 정세웅;이흥수;정용락
    • 한국물환경학회지
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    • 제24권3호
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    • pp.365-377
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    • 2008
  • Large artificial dam reservoirs and associated downstream ecosystems are under increased pressure from long-term negative impacts of turbid flood runoff. Despite various emerging issues of reservoir turbidity flow, turbidity modeling studies have been rare due to lack of experimental data that can support scientific interpretation. Modeling suspended sediment (SS) dynamics, and therefore turbidity ($C_T$), requires provision of constitutive relationships ($SS-C_T$) and accounting for deposition of different SS size fractions/types distribution in order to display this complicated dynamic behavior. This study explored the performance of a coupled two-dimensional (2D) hydrodynamic and particle dynamics model that simulates the fate and transport of a turbid density flow in a negatively buoyant density flow regime. Multiple groups of suspended sediment (SS), classified by the particle size and their site-specific $SS-C_T$ relationships, were used for the conversion between field measurements ($C_T$) and model state variables (SS). The 2D model showed, in overall, good performance in reproducing the reservoir thermal structure, flood propagation dynamics and the magnitude and distribution of turbidity in the stratified reservoir. Some significant errors were noticed in the transitional zone due to the inherent lateral averaging assumption of the 2D hydrodynamic model, and in the lacustrine zone possibly due to long-term decay of particulate organic matters induced during flood runoffs.

IMPATT 다이오드의 백여혼합에 관한 연구 (A Study on the Self-Excited Mixing effect of IMPATT Diodes)

  • 박규태;이종악;이태호
    • 대한전자공학회논문지
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    • 제11권2호
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    • pp.5-11
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    • 1974
  • IMPATT다이오드의 자기혼합효과(self mixing effect)를 이론으로 해석하고 실험으로 확인하였다. 이론은 증배과정에서 외부의 마이크로도 신호에 의하여 공간전하가 변조를 받는 것에 근거하였다. 비이트출력은 신호전력과 IMPATT다이오드발진전력에 직선적으로 비례하였고 IMPATT다이오드의 부성저항이 클수록 비이트출력이 증대하였다. 실험은 GaAs의 EPi층과 금속사이의 Schottky접합을 갖는 IMPATT다이고드를 사용하였다. 전자계산기의 계산결과 10(GHz)에서 변환이득은 -0.4[db]였으며 실험치는 비이트주파수 20(MHz)에서 -6.6[db]였다. 이 차이는 Read모델의 단순한 가정과 공진기의 구조에 의한 것이었다. 1개의 다이오드가 국부발진 및 R합작용을 동시에 수행할 수 있었으며, 또 변환이득은 일반다이오드보다 높았고 IMPATT다이오드의 발진출력에 따란 증대시킬 수 있었다.

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Evaluation of Toyocerin, a Probiotic Containing Bacillus toyoi Spores, on Health Status and Productivity of Weaned, Growing and Finishing Pigs

  • Kyriakis, S.C.;Georgoulakis, I.;Spais, A.;Alexopoulos, C.;Miliotis, C.C.;Kritas, S.K.
    • Asian-Australasian Journal of Animal Sciences
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    • 제16권9호
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    • pp.1326-1331
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    • 2003
  • The aim of the study was to assess the efficacy of Toyocerin, a probiotic containing Bacillus toyoi spores, on the health status and productivity of pigs, during nursery, growing and finishing phases. On a commercial farrow-to-finish farm in Greece, 3 experimental groups were formed, each of 72 weaned piglets. The pigs of the first group (T1 group; negative controls) received normal feed with no antimicrobials or probiotics, the pigs of the second group (T2 group) received the same type of feed but supplemented with 1.0${\times}$10$^9$, 0.5${\times}$10$^9$ and 0.2${\times}$10$^9$ spores per kg of feed at weaning, growing and finishing stage, respectively, and the pigs of the third group (T3 group) were fed with Toyocerin at the dose of 1.0${\times}$10$^9$ spores per kg of feed during the entire fattening period (weaning, growing and finishing stages). The results have shown that, compared to the controls, Toyocerin treated pigs had reduced incidence of postweaning diarrhoea (p<0.05). Enterotoxigenic strains of Escherichia coli were detected in faecal samples of 0% to 25% of pigs of the treated groups, but in 33.5% to 50% of pigs of the non-treated group (p<0.05). Over the negative controls, a significant improvement of weight gain (4.5% and 8.3% for T2 and T3 groups, respectively), and of feed conversion ratio (6.6% and 13.0% for T2 and T3 groups, respectively) was observed. The 76.5% of the carcasses of the T3 group was classified in the top three categories of the EUROP scale (S, E and U), whilst the respective figures were 47.8% for T2 group and only 10.5% for T1 group (p<0.05).