• Title/Summary/Keyword: Negative and positive forming

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A rare histopathological variant of Schwannoma with rosette-like arrangements and epithelioid cells: a case report from a histopathologist's perspective

  • Monica Mehendiratta;Vikas Kumar Sant;Manisha Lakhanpal;Keerti Chauhan
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.49 no.4
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    • pp.233-238
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    • 2023
  • Schwannomas exhibit histopathological variation that leads to diagnostic dilemmas, although less frequent in the oral cavity. We describe a case with unique histopathology and no relevant clinical history that adds to the breadth of literature on the diversity presented by Schwannoma. A 60-year-old female patient presented with a small dome-shaped, asymptomatic swelling on the alveolar ridge 6 years in duration. Histopathologically, it showed rich cellular pathology with a unique arrangement of tumor cells forming irregular rosettes. Each rosette presented with a central core of fibrin-collagenous material and the tumor cells were arranged on the periphery, exhibiting epithelioid change with evidence of mild cellular and nuclear pleomorphism. On immunohistochemical evaluation, the cells were strongly and diffusely positive for S-100 and negative for Ki-67. A diagnosis of benign Schwannoma with a rosette-like arrangement with epithelioid change was made. The case report emphasizes the risk of misdiagnosis and the importance of awareness regarding rare histopathological variants of Schwannoma.

Formation of Employment Subcenters and Regional Industry Restructuring: Focusing Wholesale and Retail Sector in Incheon

  • YOO, Byong-Kook;KIM, Soon-Hong
    • Journal of Distribution Science
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    • v.18 no.2
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    • pp.59-67
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    • 2020
  • Purpose: This study examines the relationship between formation of employment subcenters and regional industrial structures in Incheon. Research design, data, and methodology: We used the five-year panel data from 2012 to 2016 in 146 basic municipal units of Incheon to analyze panel regression models. Gross employment density and employment to population ratio were used as indicators of employment subcenters formation. The entropy index and Hachman index were used for analyzing the diversity and heterogeneity of industrial structures. Result: The analyses of two panel regression models showed that for the formation of employment subcenters, both the Entropy and Hachman index were significantly negative in most models. But tertiary industry was shown to have a significant positive relationship in all models. In the wholesale and retail sector, it was found that the average number of employees in the employment subcenters is significantly higher than that in the non-employment subcenters. Conclusions: The specialization of the industrial structure rather than the diversification contributes to the formation of the employment subcenters in Incheon. In particular, it can be considered that the wholesale and retail sector plays a very important role in forming the employment subcenters in many areas of Incheon.

Analysis on the Roles and Occupational Experiences of Social Workers in Child Care Facilities (아동양육시설 생활복지사의 역할 및 직무경험 분석)

  • Kim, Gihwa;Yang, Sungeun
    • Human Ecology Research
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    • v.55 no.6
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    • pp.581-592
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    • 2017
  • This study investigated the occupational experiences of social workers in child care facilities. The participants of the study were six social workers in child care facilities. This qualitative research used a Consensual Qualitative Research (CQR) method that and classified the main findings into five categories and twelve sub-themes. This study revealed that child care professionals define themselves as "caregivers" and "role models." Positive effects of institutional life on a child were forming peer relationships and being able to use diverse services while negative effects included acquiring a social stigma, having problems in developing attachment between a child and a surrogate caregiver, developing passive attitude and weak will power from communal living. Meanwhile, conflicts with children and poor working conditions led to burnout for caregivers. Our recommendations on the direction of change for the facilities are: categorizing admitted children, supporting restoration of family functions, reinforcing support for children's preparation for an independent life, and developing expertise. This paper provides a better understanding of child care facilities as well as encourages further social discourse on institutionalized children in order to promote policy making and implementation.

A Case Study on the Enterprises in Rural Industrial Parks Located in Miryang-si (밀양지역 농공단지 입주업체에 대한 사례 연구)

  • Hong, Chan-Sun;Lee, Han-Sung;Im, Sang-Bong;Kim, Chae-Soo;Kwon, Young-Duk
    • Proceedings of the Korean Society of Agricultural Engineers Conference
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    • 2005.10a
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    • pp.232-240
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    • 2005
  • There are positive evaluation as well as negative evaluation for Rural Industrial Park Project which was implemented since 1984 to boom up the regional economy in Korea. By conducting a survey for Rural Industrial Park enterprises located in Miryang-si, this study intends to examine the management condition of enterprises in Rural Industrial Parks and so derive the policy suggestion. According to the secondary data and the survey results, Rural Industrial Parks play an important role in the regional economy. The result of the survey shows that the enterprises are dissatisfied with excessively high distributing costs and they want improvement of roads and transportation condition. They recruit their employees mainly through advertisement and loan money from banks. One of serious problems is giving up the business due to shortage of fund or failing to find the markets. To prevent quitting business, a preliminary analysis of the feasibility of running business should be conducted. Technology and management guidance and marketing support are necessary not only for new enterprises, but for existing enterprises. Alternatives for connecting local resources and Rural Industrial Park and forming a network between local universities, institutes, and firms should be considered.

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Impact of Corporate Governance Mechanisms on Corporate Social Responsibility Disclosure of Publicly-Listed Banks in Bangladesh

  • JAHID, Md. Abu;RASHID, Md. Harun Ur;HOSSAIN, Syed Zabid;HARYONO, Siswoyo;JATMIKO, Bambang
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.6
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    • pp.61-71
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    • 2020
  • The study examines the impact of corporate governance mechanisms, such as board characteristics on corporate social responsibility disclosure (CSRD). The data on CSRD items and board characteristics have been collected by content analysis of the annual reports of 30 publicly-listed banks in Bangladesh covering six years, from 2013 to 2018. More specifically, the directors' report, the chairman's statement, notes to the financial statement and CSR disclosure reports included in annual reports were used to collect the CSRD data. The empirical analysis applies the ordinary least square and the generalized method of moments. The results of the study have revealed that board size, board independence, female board member, and foreign directors have a significant positive impact on CSRD. By contrast, political directors and audit committee size have a negative impact on CSRD. Interestingly, accounting experts on boards ensure more CSRD as they curb the influence of politicians on the board. Thus, it is better to increase accounting experts and decrease politicians on the board. These findings provide valuable insights into the process of forming a suitable CSR policy by connecting the efforts of the board, government, and regulatory bodies to enhance the performance of banks to CSR as well as to CSRD.

Site-Directed Mutation Effect of the Symmetry Region at the mRNA 5'-end of Escherichia coli aeg-46.5 Gene

  • Ahn, Ju-Hyuk;Choe, Mu-Hyeon
    • BMB Reports
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    • v.29 no.1
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    • pp.92-97
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    • 1996
  • The age-46.5 gene of Escherichia coli is induced by nitrate ion and regulated by Fnr, NarL, and NarP during anaerobic growth. aeg-46.5::lacZ fusion gene shows its maximum expression in narL host after two hours of aerobic to anaerobic switch in M9-Glc-nitrate medium. Fnr and NarP act as positive regulators, and NarL acts as a negative regulator. The control region of the aeg-46.5 was identified and the binding sites of regulator proteins have been predicted (Reznikoff and Choe (1993)). It has two symmetry regions. One is located at -52~-37 bp from the anaerobic mRNA 5'-end, which is the binding site of NarL and NarP. The other is located at +37~+56 bp from the 5'-end of mRNA. In this study, the downstream symmetry region from the mRNA 5'-end was investigated by site-directed mutagenesis. The destruction of the symmetry region increases the expression level of aeg-46.5. We propose that the symmetry region interferes with the expression of aeg-46.5 possibly by forming a stem-and-loop structure.

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A Study of Knowledge, Attitude and Needs for Education on Sex of Korea Female Students in College (여대생의 성에 대한 지식, 태도 및 교육 요구도에 관한 연구)

  • 오혜경
    • Korean Journal of Health Education and Promotion
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    • v.20 no.2
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    • pp.163-178
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    • 2003
  • This study was done to examine knowledge and attitude towards sex and the needs for sex education of korea female students in college. Data for this study was collected through questionnaires filled-out by 464 female students from September 2002 to December 2002. The result of this study were as follows; The subjects' scores of sex knowledge was 19.60 on average devided into the lovest 1 to the highest 25. Reproductive physiology scored highest at 0.82 and the contraceptive method was the lowest at 0.54. The subjects showed a positive sex attitude as 48% were for the abortions before marriage, a they appeared the most negative as 4.3% were for extramarital coitus of women. The subjects who responded that sexual education is necessary were 423 (91.2%), and they wanted ‘the sexual mentality of men and women’ most, 419 (99.1%). Also, ‘contraceptive method’ of 404 (95.5%), ‘veneral disease.’, ‘sexual behavior’, ‘sexual physiology’, ‘reproductive physiology’, ‘sexual morals’ etc followed. Based on above results of the study, it is more essential to organize the sex education programs centering around ‘contraceptive method’, ‘veneral disease.’, ‘sexual behavior’ etc which are not too difficult but more needed than ‘reproductive physiology’. It is required to develope sex education programs through research between specialists in various fields rather than through specialists in one field. It is considered that sex education programs can lead female students to forming and maintaining a correct sexual identity.

Protein Context-Dependent Hydrophobicity of Amino Acids in Protein

  • Cho, Hanul;Ham, Sihyun
    • Proceeding of EDISON Challenge
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    • 2016.03a
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    • pp.163-166
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    • 2016
  • Hydrophobicity is the key concept to understand the water plays in protein folding, protein aggregation, and protein-protein interaction. Traditionally, the hydrophobicity of protein is defined based on the scales of the hydrophobicity of residue, assuming that the hydrophobicity of free amino acids is maintained. Here, we explore how the hydrophobicity of constituting amino acids in protein rely on the protein context, in particular, on the total charge and secondary structures of a protein. To this end, we calculate and investigate the hydration free energy of three short proteins based on the integral-equation theory of liquids. We find that the hydration free energy of charged amino acids is significantly affected by the protein total charge and exhibits contrasting behavior depending on the protein total charge being positive or negative. We also observe that amino acids in the ${\beta}-sheets$ display more enhanced the hydrophobicity than amino acids in the loop, whereas those in the ${\alpha}-helix$ do not clearly show such a tendency. And the salt-bridge forming amino acids also exhibit increase of the hydrophobicity than that with no salt bridge. Our results provide novel insights into the hydrophobicity of amino acids, and will be valuable for rationalizing and predicting the strength of water-mediated interaction involved in the biological activity of proteins.

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Study on the gate cutting of light guiding plate for mobile using quenching element (박형 도광판의 음각, 양각 마이크로 패턴 성형성에 관한 연구)

  • Hwang, Chul-Jin;Kim, Jong-Sun;Min, In-Gi;Kim, Jong-Dug;Yoon, Kyung-Hwan
    • Design & Manufacturing
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    • v.2 no.5
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    • pp.1-4
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    • 2008
  • LCD-BLU (Liquid Crystal Display - Back Light Unit) is one of kernel parts of LCD unit and it consists of several optical sheets(such as prism, diffuser and protector sheets), LCP (Light Guide Plate), light source (CCFL or LED) and mold frame. The LGP of LCD-BLU is usually manufactured by forming numerous dots with $50-200{\mu}m$ in diameter on it by erosion method. But the surface of the erosion dots of LGP is very rough due to the characteristics of the erosion process during the mold fabrication, so that its light loss is high along with the dispersion of light into the surface. Accordingly, there is a limit in raising the luminance of LCD-BLU. Especially, the negative and positive micro-lens pattern fabricated by modified LiGA with thermal reflow process was applied to the optical design of LGP.

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Kinetics and Mechanism of the Addition of Anilines to β-Nitrostilbenes in Acetonitrile

  • Sung, Dae-Dong;Kang, Sang-Soo;Lee, Jong-Pal;Jung, Dae-Il;Ryu, Zoon-Ha;Lee, Ik-Choon
    • Bulletin of the Korean Chemical Society
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    • v.28 no.10
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    • pp.1670-1674
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    • 2007
  • Addition reactions of anilines (XC6H4NH2) to β-nitrostilbene (YC6H4CH=C(NO2)C6H4Y') have been investigated in acetonitrile at 30.0 oC. The magnitude of βX values (=0.11-0.34) indicates relatively earlier transition state for additions with anilines than with benzylamines. The signs of ρY and ρY' are positive with Δρ = ρY?ρY' = 0.04, demonstrating a TS imbalance with a negative charge development on the Cβ in the TS. The signs of cross-interaction constants ρXY (<0), ρXY' (<0) and ρYY' (>0) are consistent with bond forming and breaking processes. The relatively weak normal kinetic isotope effects involving deutarated nucleophiles, kH/kD>1, suggest an early, hydrogen-bonded, 4-member cyclic TS.