• Title/Summary/Keyword: Needle force

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Force Reflection for a Spine Needle Biopsy Simulator (척추침생검 시뮬레이터를 위한 힘반향 구현)

  • 권동수;경기욱;강흥식;김진국;나종범
    • Journal of Biomedical Engineering Research
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    • v.21 no.6
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    • pp.575-581
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    • 2000
  • 본 논문에서는 척추침생검 시뮬레이터에서 사용의 햅틱 디바이스인 PHANToM(sup)TM을 이용하여 사실적인 힘을 구현하는 방법을 보여준다. PHANToM(sup)TM은 툴의 끝부분에서 좌표축 방향으로만 힘을 낼 수 있는 단점이 있으며, 시스템의 구동장치의한계로 인하여 딱딱한 물체에 닿을 때 불안정한 특성을 보인다. 또한 좁은 영역 안에서 복잡한 조직들로 인한 급격한 강도 변화도 시스템의 불안정을 초래한다. 모사되는 힘은 두가지 성분으로 나뉜다. 하나는 바늘이 삽입될 때 바늘의 길이 방향으로 느껴지는 힘으로 생체 조직의 모델을 통해 값이 구해진다. 다른 하나는 바늘이 피부를 뚫고 지나간 이후에 바늘이 초기 삽입 방양을 유지 시켜주는 회전방향 힘으로 피봇을 이용하여 구현하였다. 불안정성 문제와 바늘이 튀어나오는 문제는 램핑 필터와 시간변수를 이용하여 제거하였다. 침생검 과정은 생체조직의 탄성 변형뿐 아니라 파괴가 일어나는 변형이므로 사실적인 힘을 구현하기 위해서 실험 데이터를 이용하여 삽입 깊이에 따라 탄성 계수와 마찰 상수가 변하는 모델을 제안하였다.

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Influence of Combustion Flame on Flashover Characteristics Due to Fire Occurrence (화재발생시 직류 플래시오버특성에 미치는 연소화염의 영향)

  • 하장호;김인식;정우영
    • Fire Science and Engineering
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    • v.17 no.2
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    • pp.25-34
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    • 2003
  • In this paper, characteristics of the DC flashover voltage in the horizontal air gap of sphere-sphere/needle-needle electrode system were investigated when the combustion flame of paraffin oil was present between the two electrodes. The reduction characteristic of DC flashover voltage was discussed with the thermal ionization process, the relative air density and the deflection phenomena in the shape of flames that caused by the corona wind and Coulomb's force. As the results of an experimental investigation, It was found that the reduction characteristics of DC flashover voltages with flames were affected strongly by the flame deflection and the change of relative air density. It was also found that the thermal ionization phenomena were not important in the range of combustion flame temperature.

Effect of Injection Hole and Needle-driven Characteristics on Pilot Spray in High Pressure Injector with Common-rail System (커먼레일 고압분사용 인젝터의 분공수 및 니들구동특성이 Pilot 분무에 미치는 영향)

  • Lee, Jin-Wook;Bae, Jang-Woong;Kim, Ha-Nul;Kang, Kern-Yong;Min, Kyung-Duk
    • Journal of ILASS-Korea
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    • v.9 no.1
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    • pp.8-14
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    • 2004
  • future exhaust emission limits for diesel-driven passenger cars will force the automotive company to significantly develop of the new technologies of diesel engine respectively of the drive assemblies. As we know, the contributions of soot and nitrogen oxide is the main problems in diesel engine. Recently, as a result, the pilot injection of common-rail fuel injection system recognizes an alternative function to solve an environmental problem. This study describes the effect of the nozzle structure and driven characteristic of injector on pilot injection fur a passenger car common-rail system. The pilot spray structure such as spray tip penetration, spray speed and spray angle were obtained by high speed images, which is measured by the Mie scattering method with optical system fur high-speed temporal photography. Also the CFD analysis was carried out for fuel behavior under high pressure in between needle and nozzle of injector for common-rail system to know the condition of initial injection at experiment test. It was found that solenoid-driven injector with 5-hole was faster than 6-hole injector in spray speed at same conditions and piezo-driven injector showed faster response than solenoid injector.

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Development and application of non-invasive drug delivery systems utilizing pulse power, and its application to mouse models (펄스파워를 적용한 비침습 약물 전달기 개발 및 마우스 모델로의 적용)

  • Hwi-Chan Ham;Kyu-Sik Kim;Ji-Hwan Lee;Hyung-Jin Choi;Do-Nyun Kim;Jai-Ick Yoh
    • Journal of IKEEE
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    • v.28 no.1
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    • pp.97-103
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    • 2024
  • Some drugs can offer far better medical effectiveness as it is injected through the intradermal layer of the skin, known as a needle-free injection. However, conventional needle-free devices might deliver a relatively large amount of drug in a just single spot of skin, splitting open the tissue layer structure, which might cause bruising and bleeding. By injecting the small volume with a fast repetition rate in a large surface area of skin, the patient may get much fewer injuries and pain. To achieve that specification, the driving force must be instantaneous and short-pulsed. Such a form of an injection device has been developed but the efficacy of those devices has been rarely examined. Therefore, this study developed the laser-induced microjet device that ejects microjet whose speed is ~310 m/s, during the 400~800 ㎲ of pulse time. The device can eject ~1 µL of the drug at the rate at which each shot repeated 10 shots per second. Using this specification, we evaluated the efficacy of drug injection onto mouse models. After injecting the insulin solution into the mouse model, the blood insulin level is detected, resulting in 20 % of blood insulin level with the ordinary needle syringe injection method.

Fundamental study on gene transfer utilizing magnetic force and jet injector

  • Hasegawa, T.;Nakagam, H.;Akiyama, Y.;Nishijima, S.
    • Progress in Superconductivity and Cryogenics
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    • v.19 no.1
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    • pp.9-12
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    • 2017
  • Recently, DNA vaccination is attracting attentions as a new therapeutic method for lifestyle diseases and autoimmune diseases. However, its clinical applications are limited because a safe and efficient gene transfer method has not been established yet. In this study, a new method of gene transfer was proposed which utilizes the jet injection and the magnetic transfection. The jet injection is a method to inject medical liquid by momentary high pressure without needle. The injected liquid diffuses in the bio tissue and the endocytosis is considered to be improved by the diffusion. The magnetic transfection is a method to deliver the conjugates of plasmid DNA and magnetic particles to the desired site by external magnetic field. It is expected that jet injection of the conjugates causes slight membrane disruptions and the traction of the conjugates by magnetic field induces the efficient gene transfer. In conclusion, the possibility of improvement of the gene expression by the combination of jet injection and magnetic transfection was confirmed.

Formation of $ZrO_2$ nanodots for the enhanced flux pinning properties in high $T_c$ superconducting films (초전도 자속고정 특성 향상을 위한 $ZrO_2$ 나노점의 형성 연구)

  • Chung, Kook-Chae;Yoo, Jai-Moo;Kim, Young-Kuk;Lee, Hye-Moon;Wang, X.L.;Dou, S.X.
    • Progress in Superconductivity and Cryogenics
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    • v.10 no.1
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    • pp.15-18
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    • 2008
  • To achieve high transport current without degradation under magnetic field, it is essential to artificially generate the pinning sites at which moving magnetic flux can be pinned. In this work, $ZrO_2$ nanodots were formed on the substrate surface using electro-spray deposition method. On top of the nanodots, the extended and effective pinning centers can be created. The positively charged Zr precursor solution was sprayed out from the needle using the corona discharge phenomena. Then, the sprayed precursor was deposited onto the negatively charged substrate surface followed by the heat treatment under the controlled atmosphere. Using the electrostatic force among the charged particles of precursor, evenly distributed and nano-sized dots were formed on the substrate surface. The size and density of the nanodots were studied by Atomic Force Microscopy. Also discussed are the effect of the deposition time and solution concentration on the size and density of the nanodot and processing variables in electro-spray method for the effective flux pinning centers in the superconducting films.

Fabrication of Barium Ferrite Films by Sol-Gel Dip Coating and Its Properties.

  • T. B. Byeon;W. D. Cho;Kim, T. O.
    • Journal of Magnetics
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    • v.2 no.1
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    • pp.16-21
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    • 1997
  • Those were investigated, the crystallographic, morphological, and magnetic properties of barium ferrite film (SiO2/Si substrate) prepared by sol-gel dip coating. Appropriate sol was prepared by dissolvin barium and iron nitrate in ethylene glycol at 80$^{\circ}C$. To obtain the films, thermally oxidized p-type silicon substrate with (111) of crystallographic orientation were dipped into the sol, dried at 250$^{\circ}C$ to remove organic material, and heated at 800$^{\circ}C$ for 3 hours in air for the crystallization of barium ferrite. It was found that the particles of barium ferrite formed on the substrate exhibited needle-like shape placing parallel to the substrate and its c-axis is long axis direction. There was tendency that the coercive force in horizontal direction to the substrate was higher than that in vertical direction to it. This tendency was profound in large thickness.

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Analysis of the Driving Performance in Piezo Injector for Clean Diesel Engine (친환경 디젤엔진용 차세대 피에조 인젝터의 구동성능 해석)

  • Lee, Jin-Wook;Kang, Kern-Yong;Min, Kyoung-Doug
    • Proceedings of the Korean Society of Marine Engineers Conference
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    • 2006.06a
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    • pp.33-34
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    • 2006
  • In this study, a prototype piezo-driven Injector. as a new method driven by piezoelectric energy, has been designed and fabricated based on the concept of inverse piezo-electric effect to overcome the major drawbacks of conventional solenoid-driven injector with a fixed and slow control of injection rate. The effects of an electric control between the solenoid valve and piezo-ceramic stack for injector needle's driving on the dynamic characteristics were usually investigated. We found that this piezo-electric actuator has the main advantage to drastically reducing the time of injector nozzle opening, as well to exert higher force output levels.

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Mechanism of Electrohydrodynamic Flow in AC Electrowetting (AC 전기습윤 중 전기수력학 유동의 메카니즘)

  • Lee, Ho-Rim;Ko, Sung-Hee;Yun, Sung-Chan;Kang, Kwan-Hyoung
    • Proceedings of the KSME Conference
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    • 2008.11b
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    • pp.2648-2651
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    • 2008
  • In AC electrowetting, it has been reported that there is a flow inside droplets. The flow characteristics such as flow rate, direction and the pattern of streamline are altered according to the frequency range of applied voltage. However, the mechanism of the flow has not been explained yet. This work is concentrated on investigation of the flow mechanism when high-frequency voltage is applied to droplets. We propose that this phenomenon arises from the electro-thermal flow. A numerical analysis is performed for the needle-electrode-plane geometry in which the Coulombic force term is included in the Navier-Stokes equation. According to our analysis, electrical charge is generated due to conductivity gradient which is originated from the nonuniform Joule heating of fluid medium. The result of the analysis is compared with experimental result.

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Design of Vertical Type Probe Tip Using Finite Element Analysis (유한요소해석을 이용한 수직형 프로브 팁의 설계)

  • Oh, Young-Ryun;Kim, Yun-Jae;Nam, Hyun-Suk;Park, Ung-Gi;Lee, Hak-Joo;Kim, Jung-Yub;Park, Jun-Hyub
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.36 no.8
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    • pp.851-856
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    • 2012
  • The design process of a micro-probe tip is very complicated and expensive. To avoid these problems, in this study, we used element (FE) analysis. To simplify design process. A new pre-probe tip (cobra-needle type) made of Ni and Co was designed by FE analysis. Experimental results were compared with those obtained by FE analysis to verify the reliability of the analysis. The contact force and over drive were respectively found to be 12.5 gf(Contact Force) and $100{\mu}m$(Over drive). We propose the new designed probe tip. Material of new designed probe tip is NiCo. Values of Property are 1~2 gf(Contact Force) and $100{\mu}m$(Over drive).