• 대한한방내과학회지
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• 제28권3호
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• pp.655-661
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• 2007

Malignant melanoma is rare in Asians and one of the poorer prognostic diseases. Malignant melanoma accounts for only a small ratio of all skin cancers, but it causes the greatest number of skin cancer - related deaths worldwide. Melanoma incidence has continued to increase worldwide and in Korea, like other countries, the number of patients has increased compared with previous cancer incidence data. In this case report, we describe a case of a malignant melanoma patient who showed neck node metastasis (right supraclavicular area) after wide excision of facial melanoma 2 years before the diagnosis of relapse. The patient refused to get conventional western medical treatment including chemotherapy and the size of cancer increased over the 5 months of clinical follow-up. After 4 months of traditional Korean medical treatment using allergen-removed Rhus verniciflua Stokes(A-RVS), however, the size of cancer mass decreased and the patient showed no side effects. Further study will be needed in order to determine the long-term effect of allergen-removed Rhus verniciflua Stokes on patients with malignant melanoma.

• 한국산업보건학회지
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• 제24권3호
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• pp.371-382
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• 2014

Objectives: This study was undertaken in order to examine how musculoskeletal disorder(MSD) symptoms were affected by particular factors and then to explore control strategies to prevent MSDs in general hospital nurses. Materials: This, as part of a large study, was conducted using a set of information on literature review, questionnaire survey and focus group interview. It obtained prevalence and factors of MSD symptoms and examined how MSD symptoms were distributed and affected by the factors in nurses working at 15 general hospitals across Korea. The factors were personal factors, work organization, nursing tasks, physical factors and psychosocial factors. Results: A total of 501 nurses were determined as subjects. The highest MSD symptom prevalence was 61% for the shoulder, among body parts, followed by leg/feet(55%), low back(51%), neck(42%), wrist(38%), and elbow(21%). Prevalence for the whole body was 80%. Odds ratios ranged from 0.4 to 22.4 in logistic regression analyses. The symptoms were significantly attributed to factor variables such as body mass index, current health status, daily work time, nursing task, pooled-physical factors, ergonomic factors, work load, interpersonal conflict, and job insecurity. Conclusions: Two or more factor variables were significant, depending on body part, for MSD systems in the general hospital nurses. It was noticeable that physical factors, such as pooled-physical factors, ergonomic factors or work load, were selectively significant for MSD symptoms in all body parts, indicating that such information should be used for prevention of MSDs in the hospital sector.

• 대한세포병리학회지
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• 제5권1호
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• pp.46-51
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• 1994

갑상선 미분화 "도암종"은 예후가 나쁘고 희귀한 종양으로 이 종양의 세침흡인 세포학적 소견에 관한 보고는 1990년 Pietribiasi에 의해 처음 기술된 이후 현재까지 8례가 있을 따름이다. 최근 저자들은 23세 여자의 좌측 경부의 갑상선 종괴로 부터 세침흡인 세포 검사를 시행하여 진단된 갑상선 도암종을 경험하여 그 세침흡인 세포학적 소견을 기술하는 바이다. 환자는 10년전부터 좌측 경부에 서서히 자라는 종괴를 호소하였으며 본 종괴에서 세침흡인 세포학적 검사를 시행하였다. 종괴의 세침흡인 도말은 세포밀도가 높았고 일정한 모양의 작고 둥근 세포들이 "도"구조 혹은 "지주" 구조를 보이며 간혹 개개로 산재되어 있는 세포 및 소포형태도 보였다. "도" 구조 및 "지주" 구조 내에는 미세한 소포형태가 관찰되었고 종양세포들의 핵은 자주 중첩되어 있었다. 갑상선 여포상 선종에서 보이는 성글게 배열된 소포구조도 드물게 관찰 되었다. 세포간의 크기나 모양은 거의 일정하였고 유사분열은 거의 관찰되지 않았다. 핵은 둥글고 뚜렷한 핵막과 미세하게 뭉친 염색질을 가지며 핵소체는 뚜렷하지 않았으며 드물게 젖빛 유리모양의 핵과 핵구가 관찰되었으나 유두상 구조는 관찰되지 않았다. 세포질의 경계는 불명확하였고 간혹 세포질내에 공포가 관찰되었다. 이상의 도암종의 세포학적 소견은 여포상 종양이나 유두상 종양들과는 구분되는 특징적인 소견이라 생각되며 세포학적 소견으로도 도암종의 진단이 가능하다고 생각된다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제30권3호
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• pp.228-233
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• 2004

Summary: The malignant peripheral nerve sheath tumor(MPNST) is an aggressive neoplasm and can either arise independently or result from malignant change in preexisting neurofibromatosis (von Recklinghausen's disease). Its histologic characteristics remain controversial, but currently it is believed that the schwann cell is the origin of the peripheral nerve sheath tumors. MPNST is an uncommon neoplasm of the head and neck region, and its presentation in the oral cavity is quite rare. In this study, we report a patient with a rare case of a MPNST involving the maxilla. A case report: A 29-year-old female presented with a chief complaint of painless swelling with bleeding tendency on the left maxillary tuberosity area 2 months ago. Clinical examination showed a $5.0{\times}3.0cm^2$ sized, indurative swelling on the site. Conventional radiographs showed a relatively well-defined soft tissue mass involving the left maxillary sinus, and destruction of the anterior, posterolateral walls of the left maxillary sinus. Subtotal maxillectomy and split-thickness skin graft from thigh were undertaken. In histochemical and immunohistochemical studies, the specimen revealed positive reactivities to Vimentin and S-100 protein. Final diagnosis was made as MPNST.

• Advances in pediatric surgery
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• 제6권2호
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• pp.95-99
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• 2000

Thyroid carcinoma is relatively rare in children. Eight cases of thyroid carcinoma were among 18 patients operated upon for thyroid tumors at Pediatric Surgery, Asan Medical Center in 11 years' period between 1989 and 2000. Five patients were boys and three were girls. The age distribution ranged from 10 to 14 years with a median age of 11.6 years. We studied clinical presentations, diagnostic workup, pathology, treatment, and follow-up (recurrence, mortality, and survival). All patients presented with anterior neck mass but one with multiple cervical lymph nodes enlargement. Familial history of thyroid cancer was seen in one case. All patients had a cold nodule by 1-131 thyroid scan. Fine needle aspiration (FNA) biopsy was performed in all patients. The right lobe was involved in four patients and the left lobe in two. Two had both lobes involvement. Pathologically, six cases were papillary carcinoma, one was follicular carcinoma, and one insular carcinoma. Four patients underwent unilateral lobectomy and isthmectomy. Total thyroidectomy was performed in three patients. The insular carcinoma case was preoperatively diagnosed as follicular neoplasm by FNA. After confirmation of the pathology by initial right thyroid lobectomy, total thyroidectomy was subsequently done. Cervical lymph node metastases were presented in three cases (37.5%), and lung metastasis in two cases (25%). Three patients received postoperative I-131 ablation. After a median follow-up of 53 months, all patients were alive without evidence of recurrence. In conclusion, thyroid carcinoma in children is frequently associated with lymph nodes involvement and distant metastasis, however, the prognosis is relatively good.

• 대한기관식도과학회지
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• 제6권2호
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• pp.164-171
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• 2000

Background and Objectives： Necrotizing lymphadenitis or Kikuchi's disease is characterized by cervical lymphadenopathy of unknown etiology with unique histologic findings in young female patients. The importance of this disease lies in the fact that it can be easily misdiagnosed as malignant lymphoma, hence, clinicians need to aware of this disease entity. The purpose of this study is to report the clinicopathologic findings, radiographic findings, and many laboratory tests in order to contribute to the diagnosis and treatment of necrotizing lymphadenitis. Materials and Methods： We evaluated 31 patients, who were diagnosed as necrotizing lymphadenitis by excisional biopsy or fine needle aspiration cytology or ultrasound guided 18G cutting needle biopsy, retrospectively. Result : The median age was 24.8 years (range 12 to 43 years) and the male to female ratio was 1 : 2.4(9：22), with 14 females (45.1%) under 30 years. The common chief complaints were neck mass, easy fatigue and fever. Lymph node enlargement was limited to the cervical area in most cases (28cases : 90.3%). The involved lymph nodes were usually multiple (20cases : 64.5%), unilateral (26cases 83.9%) and small sized. Leukopenia (19cases : 61.3%) and elevation of ESR (18cases : 58.1%) appeared most frequently in the abnormal laboratory data. These symptoms will be gone spontaneoulsy without any specific treatment in several weeks or months. Conclusion : We should consider open biopsy or fine needle aspiration cytology or ultrasound guided cutting needle biopsy with lymph node in patients who have cervical lymphadenopathy with easy fatigue and fever, especially young women to exclude other conditions such as malignant lymphoma and tuberculosis, etc.

• 복식문화연구
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• 제18권1호
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• pp.93-108
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• 2010

R$\ddot{o}$hrer index, Vervaeck index and Body Mass Index(BMI) are frequently used in order to judge obese subjects in clothing & textiles field. However, there are no certain criteria of judging the degree of obesity. Each researcher utilized these obesity indices according to their own criteria so far. Therefore, the purpose of the study is to suggest a reliable obesity index and new criteria for judging the degree of obesity. The results are as follows; Utilizing frequency analysis, main percentiles, minimums, maximums and ranges were presented by 5 age groups from twenties to sixties. Obesity rates dramatically increased, the subject got older. Especially, obesity rate of the subjects in their fifties and sixties were much higher than other age groups. 1.6 & higher can be used in the R$\ddot{o}$hrer index, 98 & higher can be used in the Vervaeck index, and 25 & higher can be used in the BMI as the Optimal criteria of the obesity. Total of 24 body measurements and 3 obesity indices were used for analyzing the correlation analysis. All heights measurements showed negative correlation with the 3 obesity indices. It is determined heights measurements have high correlation with R$\ddot{o}$hrer index compare to other indices. Crotch height, interscye back, neck shoulder point to breast point, bust circumference, waist circumference, upper arm circumference and armscye circumference have high positive correlation with all obesity indices. According to the ANOVAs by each percentile group of the R$\ddot{o}$hrer and Vervaeck indices, there are big significances in all measurements and obesity indices except arm length. In general, heights decreased significantly by getting bigger, while circumferences and lengths, widths and indices increased rapidly by getting bigger. The results of the analysis by each percentile group in the BMI, it showed the significant differences in the all measurements except cervical height and arm length. There were similar tendency of differences according to the degree of the obesity in BMI percentile groups. It was confirmed that the BMI is the most reliable index for judging the obesity owing to the high correlations and significant differences with other measurements.

• 대한지역사회영양학회지
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• 제8권6호
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• pp.964-976
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• 2003

The present study investigated the nutritional intake and health condition of 389 female college students living in Iksan, Jeonbuk, dependent on their frequency of breakfast. The subjects were evenly distributed in terms of their age, 61.7% were living at home with their parents, and most responded that they were from a middle income level. Of the subjects, 43.2% always had breakfast (more than 5 times a week), 26.5% sometimes (3 to 4 times a week); 30.3% seldom had breakfast (less than twice a week). The most frequent reason why they skipped breakfast was they were late risers (53%); 38.7% started to skip breakfast during their high school days. The nutritional intake based on whether or not they had breakfast showed that the intake of all nutrients including energy was higher in the students who always or sometimes had breakfast than in those who seldom did (p<0.05-0.001). The presence of clinical symptoms was dependent upon their intake of breakfast. It showed that the students who seldom ate breakfast, had more symptoms of convulsions, nervousness, neck or shoulder pain and indigestion, than those who always, or sometimes ate it (p<0.05-0.01). In all three groups, the largest number of students exercised once or twice a week. Their major reason for exercising was to lose weight. The degree of obesity based on the Body Mass Index (BMI) was in the normal range for 69.7% of the subjects. Female college students ate breakfast irregularly seemed to have a lower intake of nutrients and poorer health. In this regard, we should recognize the importance of eating breakfast, and should make a habit of doing so.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제36권3호
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• pp.217-220
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• 2010

Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is an ulcerative lesion on oral mucosa featuring as a benign mass of self-limiting growth. It can be easily misdiagnosed as squamous cell carcinoma (SCC) due to its long healing period and elevated or rolled-up margin. A 57-year old male patient who visited our department was diagnosed as SCC according to the clinical features, results of positron emission tomography (PET) and magnetic resonance imaging (MRI) of the oral lesion. However, after performing incisional biopsy, histopathologically, there were no atypical cells, but eosinophil and CD 30+ T-cells were clustered in subcutaneous and muscle tissue. It is very significant to consider this reactive lesion in the field of oral and maxillofacial surgery because of its possibility of mistaken as malignant disease. Here, we will report a couple of cases of TUGSE with references and limit of radiographic tools used for diagnosis of head and neck cancer.

• Tuberculosis and Respiratory Diseases
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• 제54권6호
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• pp.645-650
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• 2003

저자들은 우측 흉부 불편감을 주소로 내원한 25세 여자 환자를 개흉 조직 검사를 시행하여 원발성 횡격막 기원 악성 섬유성 조직구종을 진단하였고 ifosfamide, doxorubicin으로 항암 화학 요법 시행 후 부분 관해가 있었으나 진단 후 12개월째 외래 추적 검사 중 뇌전이로 사망한 젊은 여성 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.