• Journal of the Optical Society of Korea
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• 제17권2호
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• pp.172-176
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• 2013

For demonstrating widely tunable external cavity lasers operating for near-infrared (NIR) wavelength, a flexible polymer waveguide with an imbedded Bragg grating is incorporated. Due to the superior flexibility of the polymer material, the reflection wavelength of the Bragg grating is widely tunable by imposing tensile and compressive strains on the flexible Bragg grating. A third-order Bragg grating is formed on the device for facilitating the fabrication method. With a superluminescent laser diode as a gain medium of ECL, the tunable laser exhibited output power of -3 dBm and a tuning range of 32 nm.

• Medical Lasers
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• 제9권2호
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• pp.89-94
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• 2020

Photobiomodulation (PBM) therapy has been investigated to enhance and accelerate the recovery of injured peripheral nerves. Based on the wide range of benefits of PBM therapy and its clinical relevance, this study reviewed the efficacy of PBM in injured facial nerves. The search was performed in the PubMed database to find relevant articles published over the last 10 years. Four animal studies, two randomized controlled studies, one case series, and five case reports were reviewed. Despite the various parameters, functional analysis showed that PBM therapy using near-infrared irradiation has beneficial effects on the recovery of the acute phase of the damaged facial nerve, especially when related to faster functional improvement. There were no reported adverse effects of PBM therapy.

• Current Optics and Photonics
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• 제5권3호
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• pp.311-321
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• 2021

Indocyanine green (ICG) is a dye approved for use in clinical diagnostics. ICG remains in the intravascular space following intravenous administration, due to its ability to rapidly bind to the plasma proteins, and its therapeutic potential has been studied in well-vascularized cutaneous tumors. Here we have evaluated the clinical response of a subconjunctival tumor to photothermal therapy (PTT) using an ICG-enhanced near-infrared diode laser and its adverse effects, in a rabbit. 22 male New Zealand white rabbits with subconjunctival tumors were enrolled (control group 6, laser-only group 8, laser-with-ICG group 8). Rabbits in the laser-with-ICG group received ICG (twice, 2 mg/kg each time, intravenously) directly followed by irradiation with a diode laser (λ = 810 nm). Rabbits in the laser-only group were irradiated with the diode laser. ICG angiography, ultrasonography, and pathologic examination were performed to evaluate PTT response at specific time points (0, 2, and 4 weeks after PTT). Two weeks after initial treatment, the eight rabbits treated by laser with ICG showed a 100% response rate. There was no clinical response in both laser-only and control groups. ICG-PTT is a potential and effective palliative therapeutic modality for subconjunctival tumors.

• 대한기계학회논문집A
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• 제38권9호
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• pp.967-972
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• 2014

우수한 광투과성 및 경도를 지닌 유리는 바이오, 전자, 광학 등의 분야에서 널리 활용되고 있다. 하지만, 유리는 경도가 높고 깨지기 쉬워 일반적으로 특수가공법을 이용하여 가공이 이루어진다. 그 중 레이저는 공구가 불필요하며 가공 속도가 빠르다는 장점을 지니고 있지만 유리의 높은 광투과성 때문에 가공에 적용하기에는 많은 제약이 따른다. 이에 저출력의 나노초 펄스 레이저로 유리 가공을 하기 위하여 간접가공법인 레이저 습식 후면 식각공정을 활용하고자 한다. 기존의 연구들에서는 흡수율이 뛰어난 고가의 단파장 레이저 장비를 주로 사용하였으나 본 연구에서는 범용적인 근적외선 레이저 장비를 활용하여 유리 구조물 제작의 가능성을 실험하였다. 특히 깊은 구조물 제작시 발생하는 문제점을 확인하고 이를 해결하기 위해 초음파 부가 공정을 통한 미세 구조물 제작을 수행하였다.

• 한국레이저가공학회지
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• 제15권3호
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• pp.16-19
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• 2012

We have successfully formed brown colored patterns inside of a transparent borosilicate glass generally known as BK7, laying the focus of near infrared Ti: sapphire femtosecond laser beam in the bulk BK7 glass. It is important to keep the laser power well below the damage threshold of BK7 in forming the color center. According to the low laser power, there was no laser induced mechanical damage such as cracks or threads in the color formed area. From the absorbance spectrum and its gaussian fitting, we found the band gap of BK7, 4.21eV, and three absorption edges.

• 대한치과의사협회지
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• 제49권8호
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• pp.461-471
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• 2011

The detection of carious lesions is a key point to apply appropriate preventive measures or operative treatment of dental caries. A laser fluorescence device DIAGNOdent$^{(R)}$ (KaVo, Biberach, Germany) has also been shown to be of additional clinical value in the detection of initial caries. This report focus on the DIAGNOdent$^{(R)}$ for caries detection. DIAGNOdent$^{(R)}$ irradiate visible red light at a wavelength of 655 nm to elicit near-infrared fluorescence from caries lesion. This device is known as a reproducible method for caries detection, with good sensitivity and specificity especially for caries detection on occlusal and accessible smooth surfaces. DIAGNOdent$^{(R)}$ tended to be more sensitive method of detecting occlusal dentinal caries, however, showed more false-positive diagnoses than the visual inspection. So Clinician should not use the device as a clinician's primary diagnostic method and it is recommended that the device should be used in the decision-making process in relation to the diagnosis of caries as a second opinion in cases of doubt after visual inspection. The trend of modern dentistry would be a preventive approach rather than invasive treatment of the disease. This is possible only with early detection and respective preventive measures, DIAGNOdent$^{(R)}$ can help the changes.

• International Journal of Precision Engineering and Manufacturing
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• 제8권4호
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• pp.63-69
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• 2007

The two-photon stereolithography (TPS) process is a promising technique for the fabrication of real three-dimensional (3D) nano/micro-structures via application of a femto-second laser, In TPS, when a near-infrared ultrashort-pulsed laser is closely focused onto a confined volume of photocurable resin, only the local area at the center of the focus is cured. Therefore, real 3D microstructures with resolution under the diffraction limit can be fabricated through a layer-by-layer accumulative technique, This process provides opportunities to develop neo-conceptive nano/micro devices in IT/BT industries, However, a number of issues, including development of effective fabrication methods, highly sensitive and functional materials, and neo-conceptive devices using TPS, must be addressed for the realization of industrial application of TPS. In this review article, we discuss our efforts related to TPS: effective fabrication methods, diverse two-photon curable materials for high functional devices, and applications.

• 대한기계학회논문집A
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• 제39권1호
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• pp.105-109
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• 2015

고출력 레이저에 의한 영상 센서의 손상 분석 연구를 수행하였다. 고출력 레이저에 의한 금속의 손상에 관한 연구는 많이 이루어져 있지만, 상대적으로 고출력 레이저에 취약한 영상 시스템의 손상 연구는 미비한 상태이다. 본 논문에서는 CMOS 영상 센서에 고출력 레이저가 조사 되었을 때, 영상 센서가 받는 손상에 대해 실험적으로 분석하였다. 고출력 레이저 소스로는 근적외선대역의 연속발진 광섬유 레이저를 사용하였으며, 레이저 세기와 조사시간에 따른 CMOS 영상 센서의 영구적 손상 및 영상 품질을 분석하였다. 그 결과 조사시간과 레이저세기가 증가함에 따라 먼저 색상 손상이 나타나고 이후 작동불능 상태가 되었으며, 이러한 손상은 조사시간보다 레이저 세기에 더 큰 영향을 받는 것으로 나타났다.

• 대한한방소아과학회지
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• 제29권4호
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• pp.29-38
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• 2015

Objectives We aimed to identify the effectiveness of photobiomodulation using low level laser therapy (LLLT), light emitting diode (LED) and others on the growth of the length of the growth plate by reviewing literatures. Methods We searched literatures using PubMed, Science Direct, CINAHL, Korea Traditional Knowledge Portal (KTKP), Oriental Medicine Advanced Searching Integrated System (OASIS), China Knowledge Resource Integrated Database (CNKI), Japan Science and Technology Information Aggregator, Electronic (J STAGE), and Japan National Institute of Informatics Scholarly and Academic Information Navigator (CiNii) using the keywords "Growth plate" "Epiphyseal growth" "Epiphyseal plate" and "Laser", "light emitting diode (LED)", "near-infrared light", and "photobiomodulation". Search range included only original article which provided English abstract were selected. The search strategy contained no language limitation. Results A total 556 studies were found. Then, 551 were excluded by scanning titles and abstracts and finally 5 articles were selected. Five articles were RCTs using rodents. Two of the 5 articles used InGaAlP Laser (630-685 nm), and the other 3 articles used GaAlAs Laser (780, 820, and 870 nm) to investigated the effects of LLLT on the growth of the length of the epiphyseal cartilage and the number of chondrocytes and thickness of each zone of the epiphyseal cartilage. Two articles concluded that LLLT had a beneficial effect on the longitudinal growth of the growth plate. In growth of the epiphyseal plate, there were no significant differences in others. Conclusions It is might that LLLT influenced on the growth of epiphyseal plate by positive affect. However, further rigorous RCTs are warranted.

• 한국광학회지
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• 제16권6호
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• pp.535-541
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• 2005

$Cr^{4+}:YAG$ 레이저 매질을 사용하여 실온영역에서 안정적으로 수동 모드 잠금된 근적외선 펨토초 레이저를 제작하고, 그 특성을 분석하였다. 공진기 내부에 설치된 프리즘의 조절만으로 손쉬운 파장 조절이 가능하였으며, 연속 발진시 1400 nm부터 1510 nm까지 110 nm 정도, 모드 잠금 경우 1500 nm 부근에서 30 nm 정도의 파장 조절이 가능함을 확인하였다. $1.5 \%$의 투과율을 지닌 출력거울을 사용하였으며, 연속 발진시 흡수 파워가 7.6 W 일 때 최대 810 mW 이상의 출력을 측정하였다. 공진기 내에서 발생된 분산을 보상하기 위하여 적외선용 프리즘 쌍을 사용하였으며, 100 MHz의 반복률에서 푸리에 변환한계에 근접한 64 fs의 극초단 펄스 방출이 가능하였다. 레이저의 중심파장이 1510 nm 일 때 스펙트럼의 반치폭은 44 nm였다. 모드 잠금이 꺼지지 않고 장시간 안정적으로 작동이 가능한 레이저 제작을 위해 공진기 내부의 광 경로에 관을 설치하고 질소가스를 순환시켰으며, 평균출력 250 mW로 최적화하였다.