• 한국식물생명공학회:학술대회논문집
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• 한국식물생명공학회 2003년도 식물바이오벤처 페스티발
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• pp.158-158
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• 2003

• Journal of Microbiology and Biotechnology
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• 제19권12호
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• pp.1557-1564
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• 2009

Human CDX2 is known as a caudal-related homeodomain transcription factor that is expressed in the intestinal epithelium and is important in differentiation and maintenance of the intestinal epithelial cells. The caudal-related homeobox proteins bind DNA according to a helix-turn-helix structure, thereby increasing the structural stability of DNA. A cancer-tumor suppressor role for Cdx2 has been shown by a decrease in the level of the expression of Cdx2 in colorectal cancer, but the mechanism of transcriptional regulation has not been examined at the molecular level. We developed a large-scale system for expression of the recombinant, novel CDX2, in Escherichia coli. A highly purified and soluble CDX2 protein was obtained in E. coli strain BL21(DE3)RIL and a hexahistidine fusion system using Ni-NTA affinity column, anion exchange, and gel filtration chromatographies. The identity and secondary structure of the purified CDX2 protein were confirmed by MALDI-TOF MS, Western blot, and a circular dichroism analyses. In addition, we studied the DNA-binding activity of recombinant CDX2 by ELISA experiment and isolated human CDX2-binding proteins derived from rat cells by an immobilized GST-fusion method. Three CDX2-binding proteins were found in the gastric tissue, and those proteins were identified to the homeobox protein Hox-D8, LIM homeobox protein 6, and SMC1L1 protein.

• 한국산업융합학회 논문집
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• 제27권2_2호
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• pp.475-485
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• 2024

In many regions of Korea, including the Four Major Rivers, the seriousness of the problem of algal blooms due to eutrophication of water quality is being raised.In this study, in order to solve these social problems, we manufactured a filter using natural mineral fusion (red illite, zeolite, germanium ceramic, selenium ceramic, carbon ceramic) and independently developed a tank system for green algae experiments to observe and determine the stages of change in water quality. In order to study ways to improve water quality through quantitative analysis, 1 ton of severely polluted green algae water from the Nak dong River region was stored in a water tank and exposed to ultraviolet rays in the same environment as the Nak dong River. Then, the same environment as the Nak dong River was created. The results were derived from a 5-week water quality test. The results of this experiment confirmed that green-colored cyano bacteria were significantly reduced just by the turbidity results. The results were obtained through a request to the Korea Testing & Research Institute located in Changwon-si, Gyeong sang nam-do. CI-(chlorine ion) and NH3-N(ammonia nitrogen) had the effect of saving every week. The device used in this study was made of natural minerals free of heavy metals that are harmless to the human body and nature through long-term consideration and exploration to kill and prevent various strains living in water. Green purification system using natural hydrogen generating mineral filter were effective a non-chemical and physical methods. The results of this study are one way to contribute to the serious problems caused by green algae in many countries, and will contribute to the water quality environment by preventing the waste of environmental resources, improving the health of the people, and increasing the ability to purify environmental water quality at home and abroad.

• 한국동물학회:학술대회논문집
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• 한국동물학회 1997년도 한국생물과학협회 학술발표대회
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• pp.240.1-240
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• 1997

No Abstract, See Full Text

• 한국동물학회:학술대회논문집
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• 한국동물학회 2003년도 한국생물과학협회 학술발표대회
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• pp.179.2-179
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• 2003

No Abstract, See Full Text

• 약학회지
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• 제38권6호
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• pp.687-695
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• 1994

Lectin from mistletoe(Viscum coloratum) fermented by Lactobacillus plantarum for 1,2,3 days were obtained by salt fractionation, gel filtration, anion exchange chromatography and SDS-PAGE, and compared with the lectin from unfermented mistletoe. The new lectin of molecular weight of about 18,500D from fermented mistletoe was identified.

• Archives of Pharmacal Research
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• 제10권2호
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• pp.115-120
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• 1987

Methanol extract of Ilex pubescens roots prolonged bleeding time threefold, and inhibited the generation of malondialdehyde released during platelet aggregation inducted by thrombin. Through several purification procedures, its saponin, named ilexoside, was proved to be responsible for the antithrombotic activities of the plant. Ilexosides A, -D and -J and 24-carboxypomolic acid showed strong inhibitory activities on platelet aggregation induced by thrombin.

• 한국환경성돌연변이발암원학회:학술대회논문집
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• 한국환경성돌연변이발암원학회 2004년도 춘계학술대회
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• pp.129-129
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• 2004

• KIEAE Journal
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• 제5권1호
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• pp.3-10
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• 2005

Indoor air quality (IAQ) is recognized as a byproduct of industrialization that took place in the 20th century. The great attention to IAQ has been gained since 1980s, and led to numerous research studies that have mainly made in the developed countries. As the development of residential environment in Korea enters in the process of qualitative growth, IAQ has viewed as one of the core issues in the society, and research in relation to IAQ has been implemented until now in the fields of engineering and medical science. It is widely known that the sources and effects of indoor air pollution have been various, and IAQ research with multidisciplinary approaches is required. Nevertheless, few research embedded into a socio-behavioral approach to identifying interventive measures of residents and analyzing their choices is made. The purpose of this study is to examine the use of an interactive measure of residents in apartments that is air purification with phytoncide available in the market, and to investigate their self-reported effects of the air purifying substance on sick building syndrome symptoms. This study utilizes a field experiment design with pre-test and post-test, and the experiment is conducted in a natural field setting. A total of 87 test subjects from 32 households with already sick building syndrome are drawn via internet, and the participation is solely voluntary. The participants receive and use the air purifying substance, and are asked to use it continuously for two weeks and identify their self-reported symptoms of before- and after-use. The research findings indicate that air purification using phytoncide is effective to alleviate their symptoms in relation to sick building syndrome. Also it is noted that the participants report that the use of the air purification causes the positive impacts on their daily life. Further research is needed that compares the group with only humidifier and evaluates the mid-term and long-term use of the air purification and its effects.

• 융합신호처리학회논문지
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• 제19권4호
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• pp.167-173
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• 2018

빛이 부족하고 공기 순환이 원활하지 않은 실내에서 식물의 지상부와 지하부를 활용한 공기 정화 시스템을 제안한다. 제안된 시스템은 식물의 공기정화 효과를 극대화하고자 지상부는 청색과 녹색의 LED를 조합한 혼합광과 자연광에 가까운 고연색 LED를 각각 조사하고 지하부의 토양을 필터로 활용하고자 팬을 이용하여 강제 순환하였다. 광원과 팬이 결합된 실내공기정화 시스템이 식물만 배치된 경우보다 오염된 공기를 단시간에 가장 많이 제거하였다. 실내 공기정화 시스템의 혼합광과 고연색광 두 가지의 경우에서 식물만 배치된 경우보다 미세먼지는 각각 14%, 14.2%, TVOC는 7.5%, 9.4% 로 더 크게 감소하였다. 팬을 15분 동안만 가동한 실험에서도 TVOC가 97.8%로 크게 감소하였다. 식물의 광합성과 토양을 필터로 활용하는 것이 오염된 공기를 짧은 시간에 정화시킬 수 있었고 팬의 일시적인 가동으로도 지속적인 가동의 효과를 얻었다.