• Nuclear Engineering and Technology
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• v.52 no.12
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• pp.2789-2802
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• 2020

Small Modular Reactors (SMRs) are attracting wide attention due to their outstanding performance, extensive studies have been carried out for lead-based fast reactors (LFRs) that cooled with Lead or Lead-bismuth (LBE), and small modular natural circulation LFR is one of the promising candidates for SMRs and LFRs development. One of the challenges for the design small modular natural circulation LFR is to master the natural circulation thermal-hydraulic performance in the reactor primary circuit, while the natural circulation characteristics is a coupled thermal-hydraulic problem of the core thermal power, the primary loop layout and the operating state of secondary cooling system etc. Thus, accurate predicting the natural circulation LFRs thermal-hydraulic features are highly required for conducting reactor operating condition evaluate and Thermal hydraulic design optimization. In this study, a thermal-hydraulic analysis code is developed for small modular natural circulation LFRs, which is based on several mathematical models for natural circulation originally. A small modular natural circulation LBE cooled fast reactor named URANUS developed by Korea is chosen to assess the code's capability. Comparisons are performed to demonstrate the accuracy of the code by the calculation results of MARS, and the key thermal-hydraulic parameters agree fairly well with the MARS ones. As a typical application case, steady-state analyses were conducted to have an assessment of thermal-hydraulic behavior under nominal condition, and several parameters affecting natural circulation were evaluated. What's more, two characteristics parameters that used to analyze natural circulation LFRs natural circulation capacity were established. The analyses show that the core thermal power, thermal center difference and flow resistance is the main factors affecting the reactor natural circulation. Improving the core thermal power, increasing the thermal center difference and decreasing the flow resistance can significantly increase the reactor mass flow rate. Characteristics parameters can be used to quickly evaluate the natural circulation capacity of natural circulation LFR under normal operating conditions.

• Journal of Information Processing Systems
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• v.17 no.3
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• pp.537-555
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• 2021

Many researchers have carried out studies related to programming languages since the beginning of computer science. Besides programming with traditional programming languages (i.e., procedural, object-oriented, functional programming language, etc.), a new paradigm of programming is being carried out. It is programming with natural language. By programming with natural language, we expect that it will free our expressiveness in contrast to programming languages which have strong constraints in syntax. This paper surveys the approaches that generate source code automatically from a natural language description. We also categorize the approaches by their forms of input and output. Finally, we analyze the current trend of approaches and suggest the future direction of this research domain to improve automatic code generation with natural language. From the analysis, we state that researchers should work on customizing language models in the domain of source code and explore better representations of source code such as embedding techniques and pre-trained models which have been proved to work well on natural language processing tasks.

• Archives of Pharmacal Research
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• v.19 no.6
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• pp.480-485
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• 1996

Brain GABA transaminase is inactivated by preincubation with antidepressant/antipanic drug pheneizine (${\beta}$ethylphenylhydrazine) (mixing molar ratio 10:1) at pH 7.4. The reaction of enzyme with phenelzine was monitored by absorption and fluorescence spectroscopic methods. The inactive enzyme was fully reconstituted by addition of cofactor pyridoxal-5-phosphate. This result implies that the blocking of 1 mol of pyridoxal-5-phosphate per enzyme dimer is needed for inactivation of the enzyme. The time course of the reaction is significantly affected by the substrate .alpha.-ketoglutarate, which afforded complete protection against the loss of catalytic activity. The kinetic studies shows that phenelzine reacts with the cofactor of enzyme with a second-order rate constant of $2.1{\times}10^3M^{-1}s^{-1}$. It is postulated that the antidepressant/antipanic drug phenelzine is able to elevate the neurotransmitter GABA levels in central nervous system by inhibitory action on GABA degradative enzyme GABA transaminase.

• KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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• v.24 no.3
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• pp.167-180
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• 2018

Interest in the use of smart packaging systems for food products has increased in recent years. Therefore, food researchers are focusing on the development of new indicator based smart packaging technologies by using anthocyanin-based natural dye. Anthocyanins are one of the plant constituents known as flavonoids and responsible for the bright and attractive orange, red, purple, and blue colors of most fruits, vegetables, flowers, and some cereal grains. Indicators of natural dyes such as anthocyanins could express the quality and shelf life of perishable food products. However, the sensitivity and stability for their use in smart food packaging should be established to reach the market proposals. This review article focuses on recent studies related to use of natural dyes based on anthocyanin for smart food packaging applications. This study offers valuable insight that may be useful for identifying trends in the commercialization of natural dyes or for identifying new research areas. This review also provides food and packaging scientists with a thorough understanding of the benefits of anthocyanin-based natural dyes for shelf life indicator when applied to package material specific foods and hence can assist in accelerating commercial adoption.

• Smart Structures and Systems
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• v.9 no.4
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• pp.335-353
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• 2012

This study suggests a simple two-step method for structural vibration-based health monitoring for beam-like structures which only utilizes mode shape curvature and few natural frequencies of the structures in order to detect and localize cracks. The method is firstly based on the application of wavelet transform to detect crack locations from mode shape curvature. Then particle swarm optimization is applied to evaluate crack depth. As the Rayleigh quotient is introduced to estimate natural frequencies of cracked beams, the relationship of natural frequencies and crack depths can be easily obtained with only a simple formula. The method is demonstrated and validated numerically, using the numerical examples (cantilever beam and simply supported shaft) in the literature, and experimentally for a cantilever beam. Our results show that mode shape curvature and few estimated natural frequencies can be used to detect crack locations and depths precisely even under a certain level of noise. The method can be extended for health monitoring of other more complicated structures.

• Nuclear Engineering and Technology
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• v.52 no.7
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• pp.1409-1416
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• 2020

The study of heat transfer coefficient of supercritical water plays an important role in improving the heat transfer efficiency of the reactor. Taking the supercritical natural circulation experimental bench as the research object, the effects of power, flow, pipe diameter and mainstream temperature on the heat transfer coefficient of supercritical water were studied. At the same time, the experimental data of Chen Yuzhou's supercritical water heat transfer coefficient was collected. Through the factorial design method, the influence of different factors and their interactions on the heat transfer coefficient of supercritical water is analyzed. Through the corresponding analysis method, the influencing factors of different levels of heat transfer coefficient are analyzed. It can be found: Except for the effects of flow rate, power, power-temperature and temperature, the influence of other factors on the natural circulation heat transfer coefficient of supercritical water is negligible. When the heat transfer coefficient is low, it is mainly affected by the pipe diameter. As the heat transfer coefficient is further increased, it is mainly affected by temperature and power. When the heat transfer coefficient is at a large level, the influence of the flow rate is the largest at this time.

• Nuclear Engineering and Technology
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• v.55 no.8
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• pp.2997-3009
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• 2023

The Passive containment Air-cooling System (PAS) can effectively remove the decay heat of the modular small nuclear reactor after an accident. The details of natural convection around the dome, which is a key part of PAS, were investigated numerically in the present study. The thermal dynamics around the dome were studied through the temperature, pressure and velocity contours and the streamlines. Additionally, the formation of the buoyant plume at the top of the dome was investigated. The results show that with the increase of Ra, the lift-off point moves toward the bottom of the dome, and the eddy under the buoyant plume grows larger gradually, which enhances the heat transfer. And the heat transfer along the dome surface with different truncation angles was investigated. As the angle increases, the heat transfer coefficient becomes stronger as well. Consequently, a newly developed heat transfer correlation considering the influence of truncation angle for the dome is proposed based on the simulated results. This study could provide a better understanding of natural convection around the dome of PAS and the proposed correlation could also offer more predictive value in the improvement of nuclear safety.

• Smart Structures and Systems
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• v.24 no.3
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• pp.415-425
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• 2019

This study was carried out to evaluate the natural zeolite in producing green concrete as an effort to prevent global warming and environmental impact problems of cement industries. To achieve this target, two types of natural zeolites applied to study physical, chemical and compressive strength of concrete containing different percentages of zeolites. The results in comparison with control samples indicate that compressive strength of zeolites mixes increases with the 15% replacement of zeolite instead of cement in all types of samples. In the water-cement ratio of 0.6, results showed an increase in the compressive strength of all percentages of replacement. This results indicate that using natural zeolites could be produced a green concrete by a huge reduction and saving in the consumption of cement.

• Reproductive and Developmental Biology
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• v.42 no.1
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• pp.1-6
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• 2018

In this study, we analyzed signal transduction by equine follicle-stimulating hormone receptor (eFSHR) on sti- mulation with recombinant $eelFSH{\beta}/{\alpha}$ ($rec-eelFSH{\beta}/{\alpha}$), natural porcine FSH (pFSH), and natural human FSH (hFSH). cAMP stimulation in CHO-K1 cells expressing eFSHR was determined upon exposure to different doses (0-1450 ng/mL) of these hormones. The $EC_{50}$ value of $rec-eelFSH{\beta}/{\alpha}$ was 53.35 ng/mL. The Rmax values of $rec-eelFSH{\beta}/{\alpha}$ and pFSH were 28.12 and 2.88 ng/mL, respectively. The activity of $rec-eelFSH{\beta}/{\alpha}$ was much higher than that of natural pFSH. However, signal transduction in CHO PathHunter Parental cells expressing eFSHR was not enhanced by stimulation with natural hFSH. Thus, $rec-eelFSH{\beta}/{\alpha}$ was completely active in cells expressing eFSHR. However, natural hFSH did not invoke a signal response in cells expressing eFSHR. Particularly, natural pFSH was weakly active in the same cells. These results showed that $eelFSH{\beta}/{\alpha}$ has potent activity in cells expressing eFSHR. Thus, $rec-eelFSH{\beta}/{\alpha}$ may efficiently bind to eFSHR, where as natural hFSH does not bind to eFSHR.

• Korean Chemical Engineering Research
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• v.45 no.2
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• pp.155-159
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• 2007

A series of new dimesogenic compounds having two identical, terminal Schiff base type mesogens and a central tetramethylene spacer were synthesized. Their thermotropic and mesomorphic properties of the compounds were investigated by differential scanning calorimetry and polarizing microscopy. The compounds with X= -F, -Cl, -Br, -CN and $-OCH_3$ were enantiotropically nematic liquid crystal. In contrast, the compounds with X= -I and $-CF_3$ were non-liquid crystal. The nematic forming efficiency of the groups was in the order of -CN > $-OCH_3$ > -Br > -Cl > -F.