• 한국지구과학회지
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• 제31권6호
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• pp.656-670
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• 2010

이 연구의 목적은 기능이 극대화된 국립자연사박물관을 설립하기 위한 방안을 제시하는 데 있다. 이를 위하여 1987년부터 2009년까지 국내외 자연사박물관에 대한 방문 조사와 학술적 연구를 통하여 자연사와 자연사박물관의 기원과 변천 과정을 정리하였으며, 국내 자연사 관련 박물관의 질적 양적 수준을 국제적으로 비교 하였다. 한국의 자연사박물관 수는 세계 100위권 밖에 머물러 있고 학문적 연구 능력과 표본 관리 능력 및 출판 능력은 초보적인 수준에 머물러 있다. 특히 연구원의 수가 너무 적고 연구 기반이 구축되어 있지 않으며, 전시-교육 전문가도 턱없이 부족하여 연구 결과물과 학술지를 발간하지 못하고 있다. 이러한 문제점을 해결하고 최적화된 국립자연사박물관을 건립하기 위해서는 국립자연사박물관 설립 전에 연구-표본 관리-출판-전시-교육 기능을 활성화해야 한다.

• 한국수학교육학회지시리즈A:수학교육
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• 제49권4호
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• pp.437-462
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• 2010

The purpose of this research is to analyze the textbook contents about the natural number concepts in the Korean National Elementary Mathematics Curriculum. Understanding a concept of natural number is crucial in school mathematics curriculum planning, since elementary students start their basic learning with natural number system. The concepts of natural number have various meaning from the perspectives of pedagogical research, and the philosophy of mathematics. The natural number concepts in the elementary math curriculum consist of four aspects; counting numbers, cardinal numbers, ordinal numbers, and measuring numbers. Two research questions are addressed; (1) How are the natural number concepts focusing on counting, cardinal, ordinal, measuring numbers are covered in the national math curriculum? ; (2) What suggestions can be made to enhance the teaching and learning about the natural number concepts? Findings reveal that (1) the national mathematics curriculum properly reflects four aspects of natural number concepts, as the curriculum covers 50% of the cardinal number system; (2) In the aspect of the counting number, we hope to add the meaning about 'one, two, three, ......, and so on' in the Korean Mathematics curriculum. In the ordinal number, we want to be rich the related meaning in a set. Further suggestions are made for future research to include them ensuing number in the curriculum.

• Journal of Ginseng Research
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• 제44권5호
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• pp.704-716
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• 2020

Background: Ginsenoside Rh2 (GRh2) is a characterized component in red ginseng widely used in Korea and China. GRh2 exhibits a wide range of pharmacological activities, such as anti-inflammatory, antioxidant, and anticancer properties. However, its effects on Toxoplasma gondii (T. gondii) infection have not been clarified yet. Methods: The effect of GRh2 against T. gondii was assessed under in vitro and in vivo experiments. The BV2 cells were infected with tachyzoites of T. gondii RH strain, and the effects of GRh2 were evaluated by MTT assay, morphological observations, immunofluorescence staining, a trypan blue exclusion assay, reverse transcription PCR, and Western blot analyses. The in vivo experiment was conducted with BALB/c mice inoculated with lethal amounts of tachyzoites with or without GRh2 treatment. Results and conclusion: The GRh2 treatment significantly inhibited the proliferation of T. gondii under in vitro and in vivo studies. Furthermore, GRh2 blocked the activation of microglia and specifically decreased the release of inflammatory mediators in response to T. gondii infection through TLR4/NF-κB signaling pathway. In mice, GRh2 conferred modest protection from a lethal dose of T. gondii. After the treatment, the proliferation of tachyzoites in the peritoneal cavity of infected mice markedly decreased. Moreover, GRh2 also significantly decreased the T. gondii burden in mouse brain tissues. These findings indicate that GRh2 exhibits an antieT. gondii effect and inhibits the microglial activation through TLR4/NF-κB signaling pathway, providing the basic pharmacological basis for the development of new drugs to treat toxoplasmic encephalitis.

• 과학교육연구지
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• 제38권1호
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• pp.205-229
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• 2014

The purposes of this study were to explore what components of science communication and its level are contained in text panels of exhibitions in natural history museums and to propose its development direction of exhibition education in Korea. First, to find out the component and level of science communication contained in exhibition panels, the researcher team developed the analyzing tool which was called SEPAT (Science Exhibition Panel Analyzing Tool), then employed them to profile the component and level of science communication. Second, the researchers introduced the exemplary designed media of exhibitions to demonstrate how much science communication could be enhanced. The results were made as follows. First, the components of science communication was considerably weighted toward to 'concept' one. There were also a few 'awareness' and 'engagement', both of which were under 5% in each zone of exhibition and there was not 'NOSI' or 'opinion' embedded in the analyzed exhibitions. Second, the various type of designing exhibitions were found to promote or enhance the restrictedly represented components of science communication. It is suggestable for exhibitions to be designed through various type of 'media' to enhance science communication. Visitors are required to experience rich science communication to meet their educational needs, and exhibition developers in natural history museums and other museums are recommended to be professional in containing all components of science communication through various type of designing exhibitions.

• 수산해양교육연구
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• 제27권4호
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• pp.1172-1183
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• 2015

The purpose of this research is to analyze the recognition of the curriculum experts on 2015 integrated liberal arts and natural sciences curriculum revision. Research method is a delphi survey and the subjects are curriculum experts. The research results are as follows. Firstly, experts suggested common education for all students and students' opportunities to choose subjects. Secondly, the direction of curriculum revision was different by school level. The elementary school needs to foster convergence thinking. The middle school needs to educate common basic literacy education and the high school needs both the common education and the free choice of subjects by students. Thirdly, the separation of the liberal arts and natural sciences was caused by the separate thinking of custom, tradition and study and the separate exam application on liberal arts and natural science of college scholastic ability test. The solution about separation problem of liberal arts and natural sciences have been proposed to improve mathematics education and teachers' convergence education competency. Lastly, for the establishment of an 2015, integrated curriculum the reduction of the CSAT test area and the introduction of qualifying examination for English were required.

• Bulletin of the Korean Chemical Society
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• 제34권9호
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• pp.2697-2701
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• 2013

The solvolysis rate constants of piperonyloyl chloride (1) in 27 different solvents are well correlated with the extended Grunwald-Winstein equation, using the $N_T$ solvent nucleophilicity scale, $Y_{Cl}$ solvent ionizing scale, and I aromatic ring parameter with sensitivity values of $0.30{\pm}0.05$, $0.71{\pm}0.02$, and $0.60{\pm}0.04$ for l, m, and h, respectively. The solvent kinetic isotope effect values (SKIE, $k_{MeOH}/k_{MeOD}$ and $k_{50%MeOD-50%D2O}$) of 1.16 and 1.12 were also in accord with the values for the $S_N1$ mechanism and/or the dissociative $S_N2$ mechanism. The product selectivity values (S) for solvolysis of 1 in alcohol/water mixtures were in the range of 0.5 to 1.9, which is also consistent with the proposed unimolecular ionization mechanism.

• Bulletin of the Korean Chemical Society
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• 제26권8호
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• pp.1241-1245
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• 2005

Solvolyses of trifluoromethanesulfonyl chloride (TFMSC) in water and in aqueous binary mixtures of acetone, ethanol and methanol are investigated at 25, 35 and 45 ${^{\circ}C}$. The Grunwald-Winstein plot of first-order rate constants for the solvolytic reaction of TFMSC with YCl (based on 2-adamantyl chloride) shows marked dispersions into three separate curves for three aqueous mixtures. The extended Grunwald-Winstein plots for the solvolysis of TFMSC show better correlation. The large negative ${\Delta}S^{\neq}$ and relatively small positive ${\Delta}H^{\neq}$ reveals that the solvolytic reaction proceeds via a typical bimolecular reaction mechanism. The l and m values determined in various solvents are consistent with the proposed mechanism of the general base catalysis $S_AN/S_N2$reaction mechanism for TFMSC solvolyses based on mass law and stoichiometric solvation effect studies.

• Parasites, Hosts and Diseases
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• 제59권3호
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• pp.297-301
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• 2021

Toxoplasma gondii infection is widespread worldwide, not only posing a serious threat to human food safety and animal husbandry, but also endangering human health. The selectivity index was employed to measure anti-T. gondii activity. Hederagenin (HE) exhibited potent anti-T. gondii activity and low cytotoxicity. For this reason, HE was selected for in vivo experiments. HE showed 64.8%±13.1% inhibition for peritoneal tachyzoites in mice, higher than spiramycin 56.8%±6.0%. Biochemical parameters such as alanine aminotransferase, aspartate aminotransferase, glutathione, and malondialdehyde, illustrated that HE was a good inhibitor of T. gondii in vivo. This compound was also effective in relieving T. gondii-induced liver damage. Collectively, it was demonstrated that HE had potential as an anti-T. gondii agent.

• The Korean Journal of Ecology
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• 제18권4호
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• pp.525-531
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• 1995

The Korean government has recently announced its plan to establish the first National Museum of Natural History. However, the Korean word for natural history, jayonsa, is not a very familiar term to some academics as well as the general public. This article discusses the definition and history of natural history, describes the functions of natural history meseums, and makes suggestions to the establishment of our National Museum. Modern natural history is no longer an art of ‘stamp collecting’. It is a comprehensive scientific endeavor pursuing to enlighten the history of the planet Earth and the diversity of natural objects it contains. Natural history museum must have two museums within the museum: the outer museum for exhibition and general public education and the inner museum for research and specialist education. I hope that our National Museum of Natural History will be a place where we all get to know about Nature and thus to love her.

• 한국환경교육학회지:환경교육
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• 제18권1호
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• pp.110-119
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• 2005

The aims of this study was to investigate environmental views of national park rangers and their perspectives on natural environment interpretation as managers and to provide a basic resource to make programs regarding natural environment interpretation improve. The specially designed questionnaire was administered to twenty-five national park rangers who had worked at the southern office of Jiri Mountain National Park. Analysis results are as follows. They had have concerns with environmental problems and about preservation of natural environment. Most of them thought that the purpose of natural environment interpretation was to make change regarding public perceptions and attitudes toward natural environment. Over sixty percents of them recognized that publics had rarely participated in the natural environment interpretation program prepared by a national park. It was turned out that public had not concerned with the program because of the lack of their interests and recognitions regarding the natural environment interpretation program due to the lack of active advertisement for it. It is expected that national park rangers need to advertise the necessity of the program and to manage the program effective with more active mind as well as to develop and practice more appropriate programs for natural environment interpretation.