• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2023년도 임시총회 및 춘계학술대회
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• pp.41-41
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• 2023

Red pepper (Capsicum annuum L.) is one of the most consumed vegetable worldwide. In this study, we tried to suggest the possibility of Cheongyang pepper as a functional cosmetic material by identifying the physiological activity, especially antioxidant and whitening effects of Cheongyang pepper through bibliometric analysis and experimental studies. A bibliometric analysis was performed through co-word analysis of 8,892 papers retrieved from SCOPUS. 4 research fields were obtained by cluster mapping from VOSviewer software, among which we noted the antioxidant activity of extracts from Capsicum annum L.. Phenol as a useful ingredient of Cheongyang pepper was analyzed using HPLC (high-performance liquid chromatography). Antioxidant and whitening effects were evaluated by measuring DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity, hydrogen peroxide scavenging activity, and tyrosinase inhibitory activity. Cheongyang pepper extract showed contents of 0.106 ± 0.01 and 0.105 ± 0.02 mg/g, respectively, in the order of gallic acid and protocatechuic acid. The extract exhibited 56.95% DPPH scavenging activity and 43.97% hydrogen peroxide scavenging activity at a concentration of 1,000 ㎍/ml. In addition, 1,000 ㎍/ml of the extract inhibited tyrosinase activity by 52.44% and 42.61%, respectively in a whitening efficacy test using L-tyrosine and L-DOPA (L-3,4- dihydroxyphenylalanine) as substrates. These results suggest that Cheongyang pepper extract and its active ingredients have antioxidant and whitening effects, and the possibility of future development as a whitening functional cosmetic material.

• 한국산학기술학회논문지
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• 제21권4호
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• pp.419-427
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• 2020

잠수함과 같은 대형 복합무기체계는 일반적인 무기체계의 램(RAM: Reliability, Availability, Maintainability) 목표 값 설정 방법을 적용 및 검증하는 것은 제한적이다. 잠수함은 소나체계, 무장체계 등 다수의 무기체계로 구성되어 있어 운용형태종합 및 임무(OMS: Operational Mode Summary/MP: Mission Profile)의 다양성, 장비의 복잡성 등의 특성을 갖는 복합무기체계이기 때문이다. 따라서 기존 무기체계의 개발사례 즉, 램 목표 값 설정 사례를 분석하고, 사례에 대한 문제점 및 제한사항을 도출하여 잠수함의 램 목표 값 설정 및 검증을 위한 개선방안을 제시하였다. 또한 잠수함은 다른 무기체계와는 달리 전 세계지역을 운용환경으로 하며, 서로 다른 운용조건 및 정비조건을 가진다. 이런 이유로, 잠수함의 램 목표 값은 구성하는 모든 구성품이 아닌, 임무 필수장비와 임무 중요장비를 중심으로 설정하고 검증해야 한다. 이에 본 연구는 잠수함건조 국방획득사업 추진시 잠수함의 체계 및 장비의 물리적인 성능요구와 더불어, 요구되는 성능 램 목표 값 설정에 대하여 검증하는 방법을 잠수함의 특성을 고려한 현실성 있는 방안을 제시하였다.

• 동의신경정신과학회지
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• 제22권3호
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• pp.101-113
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• 2011

Objectives : Trend of R&D of herbal medicine for dementia treatment was examined based on the quantitative information analysis for establishing the national strategy of research on dementia treatment with oriental medicine. Methods : Definition was made to clarify the technology for development of herbal medicine for dementia treatment. Based on the initial keyword provided by experts in the field, queries were compounded to conduct search in the search engines of WoS and DWPI. The raw data (papers or patents) extracted from the initial search were examined by expert-review before objects of analysis were determined. Then, the accumulated data was analyzed in terms of year, country and organization, which led to examination of the trend of R&D. And the research performance evaluation for dementia treatment technologies was also made in terms of country, organization and researcher based on the forward citation analysis. The international cooperation intensity was examined on the basis of analysis of network by researcher before analysis results were put together to select lead researchers. Results : According to the quantitative information analysis of 1,330 articles that were selected as analysis objects, the number of papers on natural products research for dementia treatment has increased by around 4.6 times in recent five years. This indicates that the intensive studies have been underway recently. It was found to be the US that had the highest level in research filed of herbal medicine for dementia treatment and the highest capacity of international cooperation for that purpose. On the contrary, Korea had the share of papers at 5.1%, the number of countries in cooperation research at 8, and the article quality index at 0.40, showing that the qualitative level was insufficient, compared to the quantitative outcome. In particular, Korea was found to have no intensity of international cooperation among researchers. In case of patent, the results of information analysis of 305 patents selected as analysis objects demonstrated that China had the highest share while Korea had the very low frequency of patent application quantitatively. Conclusions : In this study, the research to develop herbal medicine for dementia treatment has recently drawn much attention that has spread around the globe. Therefore, these results suggest establishing the strategy to develop technology for dementia treatment with oriental medicine in the future based on quantitative information analysis.

• 원예과학기술지
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• 제32권4호
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• pp.558-570
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• 2014

This study was conducted to compare the volatile flavor compounds found in the leaves of 15 taxa of Korean native Chrysanthemum species. The volatile flavor compounds from the taxa were collected using a simultaneous steam distillation and extraction technique and were analyzed using gas chromatography/mass selective detector (GC/MSD). A total of 45 volatile flavor compounds were identified with six functional groups: 14 alcohols, 4 ketones, 19 hydrocarbons, 5 esters, 2 acids, and 1 aldehyde. The main functional group in 15 taxa of Chrysanthemum species was alcohols, accounting for 28.7% of volatile flavor compounds, followed by ketones (21.2%) and hydrocarbons (13.2%). Camphor, which is known for its antimicrobial properties, was the most abundant volatile compound (30%) in C. zawadskii ssp. latilobum and var. leiophyllum. In particular, C. indicum subspecies and C. boreale contained ${\alpha}$-thujone, which has outstanding anti-bacterial, anti-cancer, anti-inflammatory, anti-ulcer, and anti-diabetic efficacies. C. indicum var. albescens could be used in perfumes, since it showed 21 times more camphene than C. indicum. In addition, C. indicum var. acuta contained a fairly high content of 1,8-cineole, which has an inhibitory effect on mutagenesis. C. lineare contained only pentadecanoic acid compounds, whereas other taxa hexadecanoic acids. Overall, the Korean native Chrysanthemum species had considerable variation in volatile flavor compounds in their leaves. This study provides a good indication of specific potential use for various applications.

• 한국수소및신에너지학회논문집
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• 제20권1호
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• pp.38-44
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• 2009

Recently, the research focused on fuel cell hybrid vehicles (FCHVs) is becoming an attractive solution due to environmental pollution generated by fossil fuel vehicles. The proper energy control strategy will result in extending the fuel cell lifetime, increasing of energy efficiency and an improvement of vehicle performance. Battery state of charge (SoC) is an important quantity and the estimation of the SoC is also the basis of the energy control strategy for hybrid electric vehicles. Estimating the battery's SoC is complicated by the fact that the SoC depends on many factors such as temperature, battery capacitance and internal resistance. In this paper, battery charging time estimated by SoC is studied by using the speed response and current response. Hybrid system is consist of a fuel cell unit and a battery in series connection. For experiment, speed response of vehicle and current response of battery were determined under different state of charge. As the results, the optimal battery charging time can be estimated. Current response time was faster than RPM response time at low speed and vice versa at high speed.

• 생약학회지
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• 제43권2호
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• pp.137-146
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• 2012

Dipsaci Radix (Dipsacaceae) has been used as a tonic, an analgesic, anti-inflammatory and anti-complement agents in traditional herbal medicine for the therapy of low back pain, knee pain, rheumatic arthritis, traumatic hematoma, and bone fractures. A high-performance liquid chromatography-electrospray ionization-mass spectrometric method (HPLC-ESI-MS) was developed for the simultaneous quantitation method of the five compounds from the herbal drug: asperosaponin VI and asperosaponin XII (terpene glycosides), sweroside, loganin and dipsacus A(iridoid glycosides). HPLC separation of the analytes was achieved on a C18 column ($150{\times}2.0$ mm i.d., 5 ${\mu}m$) using the aqueous methanol containing 5 mM ammonium acetate with gradient flow of the mobile phase. Detection of the analytes was performed by positive ion electrospray ionization, and selected ion monitoring was used for data acquisition using m/z corresponding molecular adduct ion, $[M+NH_4]^+$ and $[M+H]^+$. Calibration graphs showed good linearity ($r^2$=0.9997) over the wide range of the analytes; intra- and inter-day precisions (RSD, %) were within 9.1% and the accuracy between 94.0-111.0%. Recoveries of the analytes through the assay procedure were in the range of 93.7-110.8%. Analytical results of the herbal drugs of Dipsaci Radix (17 samples) show wide distribution of the five marker compounds and clear difference of the species from Phlomidis Radix (4 samples). The developed method would provide a practical guide for the quality control of the herbal drug.

• 전자공학회논문지SC
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• 제44권3호
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• pp.58-63
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• 2007

GPS 신호는 수신 전력이 매우 낮으며, 민간용 신호의 경우에는 신호 구조가 잘 알려져 있어서 고의적 혹은 비고의적인 간섭에 취약하다. 많은 간섭 제거 기법이 연구되고 있으며 그 중에서 ATF가 상관전 처리 기법으로 널리 사용되고 있다. 그러나 ATF는 노치 폭과 관련된 설계 변수가 없어서 간섭을 제거하더라도 주변 주파수에 스펙트럼 손실을 가져온다. 반면 IIR 노치 필터는 노치 폭과 관련된 설계 변수가 있어서 CW 간섭에 대하여 매우 예리한 노치를 생성할 수 있으므로 스펙트럼 손실을 줄일 수 있다. 본 논문에서는 적응 알고리즘을 적용할 수 있는 구조의 IIR 노치 필터를 제시하고, 소프트웨어 신호발생기와 실제 측정치를 이용하여 성능을 평가하였으며, IIR 필터의 SNR 손실이 FiR 필터에 비하여 5dB 정도 작은 것을 확인하였다.

• 생약학회지
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• 제43권1호
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• pp.10-15
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• 2012

An accurate and sensitive analysis method was established for simultaneous determination of three bioactive compounds (glycyrrhizin, 6-gingerol and ginsenoside Rg3) in the Ejung Tang with high-performance liquid chromatography (HPLC)-photodiode array detection (DAD)-electrospray ionization (ESI)-Mass spectrometry (MS). The optimizing chromatographic separations a were acquired by an $C_{18}$ column ($5{\mu}m$, $4.6I.D{\times}250mm$, SHISHEDO) using gradient elution with water comprising 0.1% TFA(trifluoroacetic acid) and acetonitrile at a performing temperature of $35^{\circ}C$. Flow rate was 1.0 ml/min. A detection UV wavelength set at 205 nm and 250 nm. The three compounds were identified by electrospray ionization mass spectrometry. All calibration curves indicated great linear regression within test ranges ($R^2>0.9997$). The established method provided acceptable precision and accuracy. The relative standard deviations (RSDs) of intra-day and inter-day were less than 2.00% and 3.00%, respectively. The recoveries were found to range from 94.49 to 101.10% for the three compounds analyzed. These results showed that this method was effective and reliable for quality control of Eiung-Tang.

• Journal of Advanced Marine Engineering and Technology
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• 제39권4호
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• pp.443-448
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• 2015

선박용 질소산화물 저감장치의 혼합영역에서 유동혼합 성능을 개선하기 위해 스월형 혼합기가 개발되었다. 본 연구에서는 스월형 혼합기와 각단의 날개 각도가 조절 가능한 다단 스월형 혼합기가 고려되었다. 두 스월형 혼합기의 최적 날개 각도를 도출하기 위해 날개 각도가 균일지수 및 압력강하에 미치는 영향을 수치해석 기법을 이용하여 조사하였다. 스월형 혼합기에서는 혼합기의 날개 각도를 $10^{\circ}$ 에서 $80^{\circ}$ 까지 변화시킬 때, 최적의 유동혼합 성능은 베인 각도 $30^{\circ}$에서 $60^{\circ}$ 범위에서 나타났으나, 압력강하는 베인 각도 증가에 따라 선형적으로 증가하였다. 반면 다단 스월형 혼합기에서는 각 단의 날개각도를 조절함으로써 압력강하를 낮추면서도 높은 혼합성능의 유지가 가능함을 보였다.

• 산업공학
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• 제25권1호
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• pp.87-95
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• 2012

Very special and tentative considerations including emotional aspects are required to apply any new mechanism and methodologies for manufacturing fields due to several reasons. This study reviews the characteristics of manufacturing collaborations through specific cases applied digital engineering to enhance the collaboration performance in manufacturing domains. Two cases of collaboration related with automotive manufacturing process are analyzed to extract meaningful insights for better collaboration model suggestions. The first case deals the robot simulation to find out advance errors in jig and fixture design during the various welding process of body-in-whites. The effective communication protocol to share their idea and agreed schedules are essential for this collaboration. More severe requirement of collaboration between R&D and manufacturing departments are studied in the second case for e-coating process. The invisible barriers among different departments are lowered by the process application of Computer Aided Engineering which can make sure their own interesting effectively. Those technical and managerial suggestions can be used when the information system and standard process are sought to implement and update not only when innovation projects are executed.