• Title/Summary/Keyword: Nano-Encapsulation

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Effect of Encapsulation Ratio on the Phase Transition Kinetics of the SiO2 Encapsulated Paraffin Phase Change Materials (SiO2 캡슐화 파라핀 상변화 물질의 상전이 역학에 대한 캡슐화 비율의 영향)

  • Soumen, Mandal;Lee, Han-Seung
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2023.05a
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    • pp.99-100
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    • 2023
  • In this study, an approach has been made to understand the effect of encapsulation thickness of the nanoencapsulated PCMs on the phase transition kinetics. Paraffin is encapsulated by silica via single pot polycondensation reaction. Different ratios of silica precursor are chosen to encapsulate paraffin. The obtained encapsulated PCMs are identified as nano sized, as well as with increasing silica precursor, thicker silica encapsulations have been manifested with shrinking core diameter. The synthesized PCMs are characterized using various characterization techniques. Isochronal kinetic studies are done in differential scanning calorimeter (DSC) to understand about their phase transformation behaviors. This study can appreciate the cognition of the large-scale applications of PCMs into the building constructions as well as the fundamental conception on the phase transition kinetics of PCMs can also be amended.

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Cosmetic Application of Bis-ethylhexyloxyphenolmethoxyphenyltriazine (BEMT) Loaded Solid Lipid Nano-particle (SLN) (비스에칠헥실옥시페놀메톡시페닐트리아진(BEMT)을 봉입한 고형지질나노입자(Solid Lipid Nano-particle)의 화장품 응용)

  • Lee, Geun-Soo;Lee, Dong-Whan;Pyo, Hyeung-Bae;Choi, Tae-Boo
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.33 no.4
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    • pp.219-225
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    • 2007
  • Bis-ethylhexyloxyphenolmethoxyphenyltrizine (BEMT) is one of the most widely used chemical UVA+UVB double absorbers in sunscreen products. But topical application of BEMT is restricted due to its defects in product. The purpose of this study is to adopt the sunscreen product of solid lipid nano-particles containing BEMT (BEMT-SLN). The particle diameters, the encapsulation efficiencies and the crystallization index (C.I.) are about 330nm, 93.3 % and the 4.3 %. As a result, in vitro penetration and release of BEMT were generally higher in O/W emulsion than the SLN formulation. However in vivo study, it was shown that the rate of release could be decreased by 80 % in the SLN formulation. The sun protection factor (SPF) of the SLN formulation increased by 100 % in the in vitro UV protection test. Therefore, SLN formulation potentiated the UV-blocking power of BEMT. This study suggest that SLN can be used for the encapsulation of BEMT.

Enhancement of the Cosmeceutical Activity by Nano-encapsulation of Thiamine Di-lauryl Sulfate (TDS) with antimicrobial efficacy (항균 효능이 있는 비타민 B1 유도체(Thiamine Dilauryl Sulfate:TDS)의 나노입자화를 통한 기능성 향장 활성 증진)

  • Seo, Yong Chang;No, Ra Hwan;Kwon, Hee-Seok;Lee, Hyeon Yong
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.39 no.3
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    • pp.205-213
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    • 2013
  • This study was to improve cosmetical activity of thiamine di-lauryl sulfate (TDS) by encapsulation of nanoparticle with lecithin. Results showed that most of the nanoparticles containing the TDS were well formed in round shape with below 150 ~ 200 nm diameter as well as they were fairly stable in various pH ranges by measuring zeta potentials. The nanoparticles of TDS resulted in 85% cell viability of human normal fibroblast cells (CCD-986sk) when added at the highest concentration (1.0 mg/mL). The nanoparticles of Acer mono sap showed highest free radical scavengering effect as 88.1% in adding sample (1.0 mg/mL), compared to TDS solution of non-encapsulation (81.6%). The nanoparticles of TDS reduced the expression of MMP-1 on UV-irradiated CCD-986sk cells down to as 41.4%. The TDS solution and nanoparticles showed significant anti-microbial activities agaionst the salmonella typhimurium and listeria monocytogenes at 5 and 6 days as compared with control. Anti-microbial activities of TDS nanoparticles were similar to positive control. These results indicated that TDS nanoparticles may be a source for functional cosmetic agents capable of improving cosmetical activity such as antioxidant, whitening, and anti-wrinkling effects and can be further developed as natural preservative in cosmetics.

The Development of Whitening Cosmetic Ingredient Having Activity of Melanin Degradation (멜라닌 분해능을 지닌 미백용 기능성 화장품원료의 개발)

  • Kang, Whan-Koo;Hwang, Sun-Duk;Kim, Hyoung-Sik;Jeung, Jong-Sik;Lee, Bheong-Uk
    • KSBB Journal
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    • v.22 no.1
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    • pp.7-15
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    • 2007
  • Extensive research was carried out for inhibition of melanin formation as development of whitening cosmetic ingredients. But degradation of melanin itself was not intensively pursued as development of cosmetics. In this study, novel melanin degradation enzyme was developed and characterized. Also this enzyme production process was optimized and formulation was tried using micro encapsulation technique.

Electrospraying of Micro/Nano Particles for Protein Drug Delivery (단백질 약물 전달을 위한 마이크로/나노 입자의 전기분무 제조법)

  • Yoo, Ji-Youn;Kim, Min-Young;Lee, Jong-Hwi
    • Polymer(Korea)
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    • v.31 no.3
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    • pp.215-220
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    • 2007
  • The control of the surface energy by electrohydrodynamic force provides electrospraying with various potential advantages such as simple particle size control, mono-dispersity, high recovery, and mild processing conditions. The advantages are quite helpful to improve the stability of protein drug and control its release. Herein, the nano-encapsulation of protein drugs using electrospraying was investigated. Albumin as a model protein was processed using uniaxial and co-axial electrospraying, and chitosan, polycaporlactone (PCL), and poly (ethylene glycol) (PEG) were used as encapsulation materials. The major processing parameters such as the conductivity of spraying liquids, flow rate, the distance of electrical potential gradient, etc were measured to obtain the maximum efficiency. In the chitosan systems, mean particles size decreases as flow rate and the distance between nozzle and the collecting part decreases. In the uniaxial technique of the PCL systems, mean particles size decreases as flow rate decreases. In the coaxial technique of the PCL systems, it was found that the particles size gets larger under the application of the higher ratio of inner-to-outer liquid flow rates. The primary particles formed out of an electrospraying nozzle showed narrow particle size distribution, but once they arrived to the collecting part, aggregation behavior was observed obviously. Efficient nano-encapsulation of albumin with PCL, PEG, and chitosan was conveniently achieved using electrospraying at above 12 kV.

Enhancement of Antimicrobial Activity of Nano-Encapsulated Horseradish Aqueous Extracts Against Food-Borne Pathogens (고추냉이 수용성 추출물의 나노 입자화를 통한 식중독 미생물에 대한 항균 활성 증진)

  • Seo, Yong-Chang;Choi, Woon-Yong;Kim, Ji-Seon;Zou, Yun-Yun;Lee, Choon-Geun;Ahn, Ju-Hee;Shin, Il-Shik;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
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    • v.18 no.6
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    • pp.389-397
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    • 2010
  • This work was to improve antimicrobial activities of horseradish by encapsulated with edible biopolymers such as lecithin and gelatin since it has been difficult to directly use horseradish extracts into foods and food containers due to its strong and undesirable flavors. It was shown that most of the nanoparticles containing the extracts were well formed in round shape with below 400 nm diameter as well as fairly stable and less odd flavors in various pH ranges by measuring zeta potentials. The encapsulation efficiencies of nanoparticles were estimated as 66.6% and 53.4% for lecithin and gelatin, respectively. Minimal Inhibitory Concentration (MIC) of both nanoparticles against G(+), Listeria monocytogenes and G(-), Salmonella typhimurium were also measured as 79 ppm based on AIT concentrations in the extracts, whose activities were about 65% higher than the case of adding crude extract. It was also found that the nanoparticles efficiently penetrated into the cell membrane and started to destruct the cells after 6 hours cultivation under Transmision Electron Microscopy observation. These results prove that the nano-encapsulation of the horseradish extracts can be employed to directly treat into the foods and food containers for antimicrobial purposes with the aids of aerosolization system, by using small amounts of the extracts and having less flavors due to masking effects of nanoparticles.

ALD-based Functional Bragg Reflector Structure to Block Harmful Ultraviolet Rays that Affect the Reliability of Organic Devices (유기소자의 신뢰성에 영향을 주는 유해 자외선을 차단하기 위한 ALD기반 기능성 브래그반사경 구조)

  • Hyeun Woo Kim;Hyeong Jun Lee;Seungmi Jang;Hyeongjun Yun;Dokyun Lee;Yongmin Lee;Sangyeon Park;Jihoon Jung;Seokjun Lim;Jeong Hyun Kwon
    • Journal of the Semiconductor & Display Technology
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    • v.22 no.4
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    • pp.103-107
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    • 2023
  • To solve the reliability problem of organic devices that are often used outdoors, multifunctional gas barriers that block reactive gases such as moisture and oxygen and reflect harmful light such as ultraviolet rays are needed. In this study, ALD nanolaminate-based optically functional n-DBR was developed to overcome the poor gas permeability of polymer substrates and protect organic devices from harmful light. n-DBR not only achieved a WVTR of 8.76 × 10-6 g·m-2·day-1, but also showed a visible light transmittance of 94.3% and an ultraviolet ray blocking ability of 2.67%. In particular, n-DBR based on a nanolaminate structure maintained its permeability characteristics even in a high temperature and high humidity environment despite being used as a layer of Al2O3. This functional barrier Structure can not only be used as a functional encapsulation barrier for the reliability of organic devices, but can also be used as a tinting film for vehicles.

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PLR (Plastic Lithium Rechargeable) Batteries using Nanoscale Materials : A Convenient Source of Electrical Energy for the Future?$\dag$

  • G. Campet;N. Treuil;A. Poquet;S. J. Hwang;C. Labrugere;A. Deshayes;J. C. Frison;J. Portier;J. M. Reau;J. H. Choy
    • Bulletin of the Korean Chemical Society
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    • v.20 no.8
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    • pp.885-892
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    • 1999
  • This communication describes the synthesis of : (i) non-toxic and low cost nanocrystalline electrode materials, which can be prepared advantageously at low temperature ; (ii) highly conductive electrolyte membranes formed by the nano-encapsulation within a poly(acrylonitrile)-based polymer matrix of a solution of LiPF6 in organic solvants. The performances of rechargeable PLR (Plastic Lithium Rechargeable) batteries using the above mentioned components are presented.

Enhancement of Immune Activities of Peptides from Asterias amurensis Using a Nano-encapsulation Process (나노 입자 불가사리 펩타이드의 면역 활성 증진)

  • Jeong, Hyang-Suk;Oh, Sung-Ho;Kim, Seoung-Seop;Jeong, Myoung-Hoon;Choi, Woon-Yong;Seo, Yong-Chang;Choi, Geun-Pyo;Kim, Jin-Chul;Lee, Hyeon-Yong
    • Korean Journal of Food Science and Technology
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    • v.42 no.4
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    • pp.424-430
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    • 2010
  • Immuno-modulatory activities of peptides from Asterias amurensis were investigated using a nano-encapsulation process. The molecular weights of the peptides in the range of 5-7 kDa were separated using Sephadex G-75 gel filtration. Eighty-five percent of the nano-particles were in the 300 nm range using dynamic light scattering. The cytotoxicity of the A. amurensis nano-particles against CCD-986sk human dermal fibroblast cells was 11.64% after adding 1.0 mg/mL of the samples, which was lower than that from the control (13.28% collagen). The secretion of $NO^-$ from macrophages was estimated as $40\;{\mu}M$ after adding 1.0 mg/mL of gelatin nano-particles, which was higher than the others. Prostaglandin $E_2$ production from UV-induced human skin cells decreased greatly to 860 pg/mL after adding 1.0 mg/mL of the samples. Confocal microscopy revealed that nano-particles effectively penetrated the cells within 1 hour. From these results, we consider that nano-encapsulation of the peptides from A. amurensis can improve their biological functions.

Study on Encapsulation Efficiency and Preparation of SLN Using Conjugated New Whitening Agent(LA-PEG) and Its Cosmetic Application (새로운 미백물질을 함유하는 SLN의 제조와 봉입효율에 관한 연구)

  • Kang, Ki-Choon;Pyo, Hyeong-Bae;Lee, Cheong-Hee;Kim, Tae-Hoon;Ma, Sang-Chol;Im, Won-Cheol;Jeong, Noh-Hee
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.34 no.1
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    • pp.15-23
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    • 2008
  • This study is on encapsulation of a new whitening agent, LA-PEG using solid lipid nanoparticle(SLN) method, one of nanoparticle preparation method. Classical method has high capsulation efficiency for hydrophobic compounds but has demerit of low capsulation efficiency($2{\sim}3%$) for hydrophilic compounds. Purpose of this study is preparation of SLN that has higher skin penetration effect compared with general liposome, and also has higher encapsulation efficiency of hydrophilic compounds. For SLN preparation, coconut oil, macadamia oil, and jojoba oil were used. As a result, SLN preparation using coconut oil(include LA-PEG) has the most high encapsulation efficiency and also has the smallest average particle size(270 nm). SLN prepared with macadamia oil and 1% of Tween 60 has the largest particle size. Base made with coconut oil and 2% of Tween 60 showed the fastest release and base made with macadamia oil and 2% of Tween 20 showed the latest release.