• Title/Summary/Keyword: Nano sensor

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Label-free Femtomolar Detection of Cancer Biomarker by Reduced Graphene Oxide Field-effect Transistor

  • Kim, Duck-Jin;Sohn, Il-Yung;Jung, Jin-Heak;Yoon, Ok-Ja;Lee, N.E.;Park, Joon-Shik
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.02a
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    • pp.549-549
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    • 2012
  • Early detection of cancer biomarkers in the blood is of vital importance for reducing the mortality and morbidity in a number of cancers. From this point of view, immunosensors based on nanowire (NW) and carbon nanotube (CNT) field-effect transistors (FETs) that allow the ultra-sensitive, highly specific, and label-free electrical detection of biomarkers received much attention. Nevertheless 1D nano-FET biosensors showed high performance, several challenges remain to be resolved for the uncomplicated, reproducible, low-cost and high-throughput nanofabrication. Recently, two-dimensional (2D) graphene and reduced GO (RGO) nanosheets or films find widespread applications such as clean energy storage and conversion devices, optical detector, field-effect transistors, electromechanical resonators, and chemical & biological sensors. In particular, the graphene- and RGO-FETs devices are very promising for sensing applications because of advantages including large detection area, low noise level in solution, ease of fabrication, and the high sensitivity to ions and biomolecules comparable to 1D nano-FETs. Even though a limited number of biosensor applications including chemical vapor deposition (CVD) grown graphene film for DNA detection, single-layer graphene for protein detection and single-layer graphene or solution-processed RGO film for cell monitoring have been reported, development of facile fabrication methods and full understanding of sensing mechanism are still lacking. Furthermore, there have been no reports on demonstration of ultrasensitive electrical detection of a cancer biomarker using the graphene- or RGO-FET. Here we describe scalable and facile fabrication of reduced graphene oxide FET (RGO-FET) with the capability of label-free, ultrasensitive electrical detection of a cancer biomarker, prostate specific antigen/${\alpha}$ 1-antichymotrypsin (PSA-ACT) complex, in which the ultrathin RGO channel was formed by a uniform self-assembly of two-dimensional RGO nanosheets, and also we will discuss about the immunosensing mechanism.

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Low Rate VLC Receiver Design Using NCP302 Voltage Detector for IoT/IoL Connected Smart Homes

  • Lee, Beomhee;Mariappan, Vinayagam;Khudaybergenov, Timur;Han, Jungdo;Cha, Jaesang
    • International journal of advanced smart convergence
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    • v.7 no.4
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    • pp.50-56
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    • 2018
  • The Internet of Things (IoT) and Visible Light Communication (VLC) is opening up new services in lighting industry by integrating sensory network features in addition to standard illumination functionality. In this progressive developments, the next generation lighting devices for smart homes are capable to sense the environmental conditions and transfer the captured data through lights to gateway controller to access remotely. The smart home environmental sensor information's are few kbps only so VLC systems need to built-in with low rate light connectivity to transfer data to the gateway. To provide error free communication, the quality of a received light signal is important to be considered when designing an VLC receiver. Therefore, this paper proposes the design of robust low rate IoL receiver design using NCP302 voltage detector for micro controller to adapt the IoT/IoL front end module for system integration. To evaluate the proposed system performance, the Arduino UNO based IoT/IoL controller designed with lighting, sensors and lights connectivity interfaces. The experimental result shows that the robust interference rejection is feasible on proposed VOL receiver and possible to have an error-free communication up to 10 kbps at a low SNR using OOK modulation.

Light-emitting Diodes based on a Densely Packed QD Film Deposited by the Langmuir-Blodgett Technique (랭뮤어-블롯젯을 통해 형성된 고밀도 양자점 박막과 이를 기반으로 한 발광다이오드)

  • Rhee, Seunghyun;Jeong, Byeong Guk;Roh, Jeongkyun
    • Journal of Sensor Science and Technology
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    • v.31 no.4
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    • pp.249-254
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    • 2022
  • To achieve high-performance colloidal quantum dot light-emitting diodes (QD-LEDs), the use of a densely packed QD film is crucial to prevent the formation of leakage current pathways and increase in interface resistance. Spin coating is the most common method to deposit QDs; however, this method often produces pinholes that can act as short-circuit paths within devices. Since state-of-the-art QD-LEDs typically employ mono- or bi-layer QDs as an emissive layer because of their low conductivities, the use of a densely packed and pinhole-free QD film is essential. Herein, we introduce the Langmuir-Blodgett (LB) technique as a deposition method for the fabricate densely packed QD films in QD-LEDs. The LB technique successfully transfers a highly dense monolayer of QDs onto the substrate, and multilayer deposition is performed by repeating the transfer process. To validate the comparability of the LB technique with the standard QD-LED fabrication process, we fabricate and compare the performance of LB-based QD-LEDs to that of the spin-coating-based device. Owing to the non-destructiveness of the LB technique, the electroluminescence efficiency of the LB-based QD-LEDs is similar to that of the standard spin coating-based device. Thus, the LB technique is promising for use in optoelectronic applications.

Design and Analysis of Coaxial Optical System for Improvement of Image Fusion of Visible and Far-infrared Dual Cameras (가시광선과 원적외선 듀얼카메라의 영상 정합도 향상을 위한 동축광학계 설계 및 분석)

  • Kyu Lee Kang;Young Il Kim;Byeong Soo Son;Jin Yeong Park
    • Korean Journal of Optics and Photonics
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    • v.34 no.3
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    • pp.106-116
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    • 2023
  • In this paper, we designed a coaxial dual camera incorporating two optical systems-one for the visible rays and the other for far-infrared ones-with the aim of capturing images in both wavelength ranges. The far-infrared system, which uses an uncooled detector, has a sensor array of 640×480 pixels. The visible ray system has 1,945×1,097 pixels. The coaxial dual optical system was designed using a hot mirror beam splitter to minimize heat transfer caused by infrared rays in the visible ray optical system. The optimization process revealed that the final version of the dual camera system reached more than 90% of the fusion performance between two separate images from dual systems. Multiple rigorous testing processes confirmed that the coaxial dual camera we designed demonstrates meaningful design efficiency and improved image conformity degree compared to existing dual cameras.

Preparation of Flexible 3D Porous Polyaniline Film for High-Performance Electrochemical pH Sensor (고성능 전기 화학 pH 센서를 위한 유연한 3차원 다공성 폴리아닐린 필름 제조)

  • Park, Hong Jun;Park, Seung Hwa;Kim, Ho Jun;Lee, Kyoung G.;Choi, Bong Gill
    • Applied Chemistry for Engineering
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    • v.31 no.5
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    • pp.539-544
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    • 2020
  • A three-dimensional (3D) porous polyaniline (PANI) film was fabricated by a combined photo-and soft-lithography technique based on a large-area nanopillar array, followed by a controlled chemical dilute polymerization. The as-obtained 3D PANI film consisted of hierarchically interconnected PANI nanofibers, resulting in a 3D hierarchical nanoweb film with a large surface and open porous structure. Using electrochemical measurements, the resulting 3D PANI film was demonstrated as a flexible pH sensor electrode, exhibiting a high sensitivity of 60.3 mV/pH, which is close to the ideal Nernstian behavior. In addition, the 3D PANI electrode showed a fast response time of 10 s, good repeatability, and good selectivity. When the 3D PANI electrode was measured under a mechanically bent state, the electrode exhibited a high sensitivity of 60.4 mV/pH, demonstrating flexible pH sensor performance.

Evaluation of Pretreatment Effect and Non-enzymatic Glucose Sensing Performance of Carbon Fibers Tow Electrode (탄소섬유 토우의 전처리 효과와 비효소적 포도당 센싱 성능 평가)

  • Min-Jung Song
    • Korean Chemical Engineering Research
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    • v.62 no.1
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    • pp.13-18
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    • 2024
  • To develop flexible electrode materials for wearable devices, we investigated the electrochemical characteristics of carbon fibers tow according to pretreatment. And an electrochemical non-enzymatic sensor was fabricated using glucose as a target. The carbon fibers tow was pretreated through desizing and activation processes, and activation was performed in two ways: chemical oxidation and electrochemical oxidation. Surface morphology of carbon fibers tow samples was observed by SEM and their electrochemical characteristics and sensing performance were investigated by cyclic voltammetry, electrochemical impedance spectroscopy and chronoamperometry. Carbon fibers tow samples showed improved electrochemical properties such as reduced Ret, ΔEp, and increased Ip through pretreatment. And similar electrochemical properties were obtained with both activation methods. We selected electrochemically activated carbon fibers tow as the final electrode material for application of electrochemical sensor. The non-enzymatic glucose sensor based on this electrode has an enhanced sensitivity of 0.744 A/mM (in a linear range of 0.09899~3.75423 mM) and 0.330 mA/mM (3.75423~50 mM), respectively. Through this study, the possibility of using carbon fibers tow was confirmed as an electrode material. It is expected to be used as basic research for development of high-performance flexible electrode materials.

Electrochemical Characteristics of Pencil Graphite Electrode Through Surface Modification and its Application of Non-enzymatic Glucose Sensor (표면 개질된 샤프심 전극의 전기화학적 특성 고찰 및 비효소적 글루코스 센서 활용)

  • Min-Jung Song
    • Korean Chemical Engineering Research
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    • v.62 no.2
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    • pp.147-152
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    • 2024
  • Most medical sensors are disposable products. In order to reduce inspection and diagnosis costs, it is more important to develop the inexpensive electrode materials. We fabricated the CuO NPs/PANI/E-PGE as an electrode material for disposable electrochemical sensors and applied it to a non-enzymatic glucose sensor. For surface activation of PGE, pretreatment was performed using chemical and electrochemical methods, respectively. Electrochemical properties according to the pretreatment method were analyzed through chronoamperometry (CA), cyclic voltammetry (CV) and electrochemical impedance (EIS). From these analytical results, the electrochemically pretreated PGE (E-PGE) was finally adopted. The non-enzymatic glucose sensor based on CuO NPs/PANI/E-PGE shows sensitivity of 239.18 mA/mM×cm2 (in a linear range of 0.282~2.112 mM) and 36.99 mA/mM×cm2 (3.75423~50 mM), detection limit of 17.6 μM and good selectivity. Based on the results of this study, it was confirmed that the modified PGE is a high-performance electrode material. Therefore, these electrodes can be applied to a variety of disposable sensors.

SnO2 Semiconducting Nanowires Network and Its NO2 Gas Sensor Application (SnO2 반도체 나노선 네트웍 구조를 이용한 NO2 가스센서 소자 구현)

  • Kim, Jeong-Yeon;Kim, Byeong-Guk;Choi, Si-Hyuk;Park, Jae-Gwan;Park, Jae-Hwan
    • Korean Journal of Materials Research
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    • v.20 no.4
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    • pp.223-227
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    • 2010
  • Recently, one-dimensional semiconducting nanomaterials have attracted considerable interest for their potential as building blocks for fabricating various nanodevices. Among these semiconducting nanomaterials,, $SnO_2$ nanostructures including nanowires, nanorods, nanobelts, and nanotubes were successfully synthesized and their electrochemical properties were evaluated. Although $SnO_2$ nanowires and nanobelts exhibit fascinating gas sensing characteristics, there are still significant difficulties in using them for device applications. The crucial problem is the alignment of the nanowires. Each nanowire should be attached on each die using arduous e-beam or photolithography, which is quite an undesirable process in terms of mass production in the current semiconductor industry. In this study, a simple process for making sensitive $SnO_2$ nanowire-based gas sensors by using a standard semiconducting fabrication process was studied. The nanowires were aligned in-situ during nanowire synthesis by thermal CVD process and a nanowire network structure between the electrodes was obtained. The $SnO_2$ nanowire network was floated upon the Si substrate by separating an Au catalyst between the electrodes. As the electric current is transported along the networks of the nanowires, not along the surface layer on the substrate, the gas sensitivities could be maximized in this networked and floated structure. By varying the nanowire density and the distance between the electrodes, several types of nanowire network were fabricated. The $NO_2$ gas sensitivity was 30~200 when the $NO_2$ concentration was 5~20ppm. The response time was ca. 30~110 sec.

Characteristics of CuO doped WO3-SnO2 Thick Film Gas Sensors (CuO가 첨가된 WO3-SnO2 후막 가스센서 특성 연구)

  • Lee, Don-Kyu;Shin, Deuck-Jin;Yu, Il
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.23 no.12
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    • pp.956-960
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    • 2010
  • CuO doped $WO_3-SnO_2$ thick film gas sensors were fabricated by screen printing method on alumina substrates and heat-treated at $350^{\circ}C$ in air. The effects of mixing ratio of $WO_3$ with $SnO_2$ on the structural and morphological properties of $WO_3-SnO_2$ were investigated X-ray diffraction and Scanning Electron Microscope. The structural properties of the $WO_3-SnO_2$:CuO thick film by XRD showed that the monoclinic of $WO_3$ and the tetragonal of $SnO_2$ phase were mixed. Nano CuO was coated on the $WO_3-SnO_2$ surface and then the surface of $WO_3$ was coated with $SnO_2$ particles with $1\sim1.5{\mu}m$ in diameters, as confirmed form the SEM image. The sensitivity of the $WO_3-SnO_2$:CuO sensor to 2000 ppm $CO_2$ gas and 50 ppm $H_2S$ gas for the various ratio of $WO_3$ and $SnO_2$ was investigated. The 4 wt% CuO doped $WO_3-SnO_2$(75:25) tkick films showed the highest sensitivity to $CO_2$ gas and $H_2S$ gas.

An Experimental Study of Transient Hot-wire Sensor Module for Measuring Thermal Diffusivity of Nanofluids (나노유체의 열확산율 측정을 위한 비정상열선법 센서모듈 실험)

  • Lee, Shin-Pyo
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.35 no.2
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    • pp.113-120
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    • 2011
  • A technique for measuring the thermal diffusivity of nanofluids is proposed in this study. In theory, it has been well known that the transient hot-wire method can be used to measure the thermal conductivity and diffusivity of fluids simultaneously. However, when traditional methods were employed, the accuracy of the calculated thermal conductivity was considerably higher than that of diffusivity. The proposed method has two advantages for practical use: it only needs a simple data-conversion process for calculating the diffusivity, and it can skip the tedious calibration process involved in the case of a wire sensor. A validation experiment for the new system has been performed with the basic fluids, and the comparison experiment to compare the change in diffusivity of the base oil and the change in diffusivity of the nano oil has been carried out. It is expected that the present system will provide numerous methods for investigating the variation in the thermal properties other than thermal conductivity.