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Consanguinity Protecting Effect Against Breast Cancer among Tunisian Women: Analysis of BRCA1 Haplotypes

  • Medimegh, Imen;Troudi, Wafa;Omrane, Ines;Ayari, Hajer;Uhrhummer, Nancy;Majoul, Hamdi;Benayed, Farhat;Mezlini, Amel;Bignon, Yves-Jean;Sibille, Catherine;Elgaaied, Amel Benammar
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.9
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    • pp.4051-4055
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    • 2015
  • The purpose of this study is to assess the effect of consanguinity on breast cancer incidence in Tunisia. We conducted a case-control study to evaluate the involvement of heterozygote and homozygote haplotypes of BRCA1 gene SNPs according to consanguinity among 40 cases of familial breast cancer, 46 cases with sporadic breast cancer and 34 healthy controls. We showed significant difference in consanguinity rate between breast cancer patients versus healthy controls P=0.001. Distribution of homozygous BRCA1 haplotypes among healthy women versus breast cancer patients was significantly different; p=0.02. Parental consanguinity seems to protect against breast cancer in the Tunisian population.

Employers' Perceptions of Intimate Partner Violence among a Diverse Workforce

  • Samuel, Laura J.;Tudor, Carrie;Weinstein, Marc;Moss, Helen;Glass, Nancy
    • Safety and Health at Work
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    • v.2 no.3
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    • pp.250-259
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    • 2011
  • Objectives: Intimate partner violence (IPV) is a significant global public health concern, affecting 5.3 million US individuals annually. An estimated 1 in 3 women globally are abused by an intimate partner in their lifetime, and the effects carry over into the workplace. This article examines employers' perceptions of IPV in the workplace, targeting supervisors of Latina employees. Methods: Fourteen employers and supervisors of small service-sector companies in Oregon were interviewed using semi-structured interviews. Interpretive description was used to identify themes. These qualitative interviews preceded and helped to formulate a larger workplace intervention study. Results: The following themes were found and are detailed: (1) factors associated with recognizing IPV in the workplace, (2) effects of IPV on the work environment and (3) supervisors' responses to IPV-active vs. passive involvement. Also, supervisors' suggestions for addressing IPV in the workplace are summarized. Conclusion: These findings demonstrate the need for more IPV-related resources in the workplace to be available to supervisors as well as survivors and their coworkers. The needs of supervisors and workplaces vary by site, demonstrating the need for tailored interventions, and culturally appropriate workplace interventions are needed for Latinas and other racially and ethnically diverse populations.

Manufacture of Precheese Powder by Use of Low-temperature Renneting Made from Raw Milk Using Spray Dryer

  • An, Shuo-Feng;Piao, Jing-Zhu;Chang, Oun-Ki
    • Food Science of Animal Resources
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    • v.30 no.4
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    • pp.551-559
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    • 2010
  • Among the food constituents, proteins differ in coagulation properties as compared to other constituents in food system. Especially milk protein coagulate through different pathways thus this coagulability can be used for manufacture of various dairy products or as a determinant of dairy product analysis. These milk coagulation methods include organic solvent, isoelectric point, trichloroacetic acid, Ca-sensitive casein, heavy metal ion and rennet coagulation. The coagulation experiment was performed using above parameters at $0^{\circ}C$ and $25^{\circ}C$ to find the dehydration conditions before coagulating for precheese powder making. After different chemical treatments, there was no coagulation at $0^{\circ}C$ rather at $25^{\circ}C$ whatever the mode of coagulation methods was. The appearance of precipitate with coagulation methods was quite different from above mentioned methods of coagulation illustrated by scanning electron microscope. These powders were used for fabrication of camembert cheese by renneting coagulation at $0^{\circ}C$, showing the possibility of cheese materials and of food additives for fabrication of products.

Incorporating Performance Degradation in Fault Tolerant Control System Design with Multiple Actuator Failures

  • Zhang, Youmin;Jiang, Jin;Theilliol, Didier
    • International Journal of Control, Automation, and Systems
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    • v.6 no.3
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    • pp.327-338
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    • 2008
  • A fault tolerant control system design technique has been proposed and analyzed for managing performance degradation in the presence of multiple faults in actuators. The method is based on a control structure with a model reference reconfigurable control design in an inner loop and command input adjustment in an outer loop. The reduced dynamic performance requirements in the presence of different actuator faults are accounted for through different performance reduced (degraded) reference models. The degraded steady-state performances are governed by the reduced levels of command input. The reconfigurable controller is designed on-line automatically in an explicit model reference control framework so that the dynamics of the closed-loop system follow that of the performance reduced reference model under each fault condition. The reduced command input level is determined to prevent potential actuator saturation. The proposed method has been evaluated and analyzed using an aircraft example against actuator faults subject to constraints on the magnitude and slew-rate of actuators.

Seniors Perception on Age-Friendly Aspects in Jeju Island, South Korea - Urban vs Rural - (제주도 거주 노인의 고령친화도시에 관한 인식 조사 - 도시 vs 농촌 -)

  • Hwang, Eunju;Lee, Seo-yeon;Koh, Seung-Hahn;Brossoie, Nancy;Beamish, Julia
    • Journal of the Korean housing association
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    • v.26 no.5
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    • pp.37-44
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    • 2015
  • The purpose of this study was to compare urban and rural seniors' perceptions on the eight aspects of the World Health Organization Age-Friendly Cities (AFC) initiative on Jeju Island, South Korea. Face-to-face interviews using structured questionnaires were administered to 497 persons aged 65+ living on Jeju Island. Findings suggested that urban and rural held significantly different perceptions on five aspects of AFC (outdoor space and buildings, housing, civic participation and employment, community support and health services, and respect and social inclusion). Predictors of overall AFC score for all participants included age and living in a single-family home. Among urban dwellers, monthly household income and length of residence predicted AFC score while among rural seniors, predictors of AFC included educational attainment. To make communities more age-friendly, perspectives of older residents should be sought, shared, and reflected in policy and different strategies and priorities should be developed specific to urban and rural areas.

Individual Differences, Attitudes toward Risk Behaviors, Parents and Peers Correlates of Adolescent Risk Behaviors (청소년의 위험행동에 영향을 미치는 개인적 특성, 위험행동에 대한 태도, 부모 및 또래 변인)

  • Lee Ji-Min;Bell Nancy
    • Journal of the Korean Home Economics Association
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    • v.42 no.12 s.202
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    • pp.55-67
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    • 2004
  • The purpose of this study was to investigate the associations between adolescent risk behaviors and correlates of risk behaviors. Questionnaires were completed by 955 high school freshmen in the Daegu${\cdot}$Kyungpook area and included measures of risk behaviors, coping, self-esteem, social competence, attitudes toward risk behaviors, parental attachment, autonomy, parental monitoring, and peers' risk behaviors. The major findings were as follows. (1) Parental attachment, autonomy, and appropriate parental monitoring were positively correlated with adolescent coping, self-esteem, social competence, and peers' desirable behaviors, but were negatively associated with peers' risk behaviors and attitudes toward risk behaviors. (2) Of all the variables, peers' risk behaviors and favorable attitudes toward smoking had the greatest influence on adolescent drinking and smoking, following by favorable attitudes toward drinking, social competence, and gender (3) Similar to adolescent drinking and smoking, of all the variables, peers' risk behaviors had the greatest influence on adolescent delinquency, following by favorable attitudes toward smoking and gender.

Body Image I: A Comparison of Ideal Beauty, Body Image, and Appearance Management Behaviors Among Korean and American Women (바디이미지 연구(제1보): 한.미 여성의 이상적 미, 바디이미지와 외모행동에 관한 연구)

  • ;Nancy A. Rudd
    • Journal of the Korean Society of Clothing and Textiles
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    • v.25 no.5
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    • pp.969-980
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    • 2001
  • 이 연구의 목적은 사회.문화적 관점에서 한.미 여성의 이상적인 미, 바디이미지, 그리고 외모행동을 비교조사 하는데 있다. Open-Ended Questions에 의한 연구 결과, 이상적인 미로 미국여성이 \"키크고 마른 신체 매력성\"을 추구한 반면, 한국여성은 \"내적인 미\"와 \"서구적인 신체 매력성\"을 추구하는 것으로 나타났다. 이상적인 미를 추구하기 위해 미국여성은 주로 신체의 하체부분, 한국여성은 얼굴부분을 많이 가꾸고 있는 것으로 나타났다. 외모행동으로는 한국여성은 화장이나 피부관리 등에, 미국여성은 excercise나 다이어트 등을 많이 하고 있었다. 사회.문화적 이상적인 미에 비교해 볼 때 두 집단 모두 자신의 외모에 대해 만족하지 못하는 편으로 나타났다. 또한 두 나라 집단의 여성들은 각 나라마다 사회.문화적 이상적인 미가 각각 존재해야 함에도 불구하고 현재에는 이상적 미의 기준이 문화에 관계없이 동일한 편이라고 응답을 하였다. 본 연구에서는 사회.문화적 집단주의와 개인주의 개념을 토대로 이러한 연구결과들이 논의되어 진다.주의 개념을 토대로 이러한 연구결과들이 논의되어 진다.

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The Effect of Clothing Type and Facial Attractiveness of Men Clothed on Impressions ( I ) (남성 의복착용자의 의복유행과 얼굴의 매력성이 인상에 미치는 영향(I) -직업추론 및 의복인상을 중심으로-)

  • 이선경;고애란
    • Journal of the Korean Society of Clothing and Textiles
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    • v.19 no.2
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    • pp.230-241
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    • 1995
  • The purpose of this study was 1) to investigate the effect of male clothing type and facial attractiveness on the subjects' inferences of occupation for the wearers, 2) to investigate the effect of male clothing type on the inferences of occupational characteristics. The stimuli were composed of 24 color photographs which were made of 6 types of clothing and 18 wearers who were made of 3 levels of facial attractiveness in combination with 6 types of clothing. The subjects were 288 male and 288 female university students. The subjects chose an occupation among 19 occupations presented for 6 types of clothing and the wearers. Also the subjects' inferences of occupational characteristics for the clothing were measured by semantic\ulcornerdiffenential scales. The results were as follows: 1) As a whole, the infered occupation for each of the clothing types was consistent with the expected occupations in this study. "Therefore there were stereotypes about male clothing type. At the same time, the halo effect of facial attractiveness appeared when subjects infered wearer's occupation. 2) The subjects' responses to the semantic-differential scales about 6 types of clothing were factor analyzed to identify the underlying constructs of occupational characteristics. At the result, 4 factors were emerged. The first factor was interpreted to Apperance/ Ability, the second, Indi~iduality, the third, Naivety, and the fourth, Dominancy. 3) The male clothing type influenced on the 3 factors except the Dominancy factor.nancy factor.

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A Review of Men's Body Image Literature: What We Know, and Need to Know

  • Bradley, Linda Arthu;Rudd, Nancy;Reilly, Andy;Freson, Tim
    • International Journal of Costume and Fashion
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    • v.14 no.1
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    • pp.29-45
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    • 2014
  • In the contemporary world, fashionable bodies are socially constructed in light of current idealized images. Media portrayal of such images can have negative health implications. This issue has long been problematic for women. Nowadays, men are subject to more scrutiny regarding their bodies, although male body image has been studied far less than female body image. In this position paper based on a review of the major studies that have been conducted on men and body image, we summarize the findings from these state-of-the-art studies that have been recently published in academic journals. Three themes related to male body image were extracted: socio-cultural ideals, masculinity, and minority men. This study adds to the literature I that it demonstrates that men experience and view their bodies differently from women, though some behaviors, such as disordered eating, are similar. Other behaviors, such as the drive for muscularity, are couched in the context of the social construction of gender and power. Most of the studies were done on white, heterosexual populations of young men, and nearly all used quantitative research methods. Little research has been conducted on ethnic and sexual minorities. We conclude with a discussion of what we need to know, and to that end, we suggest future avenues of research.

Effects of load height application and pre-buckling deflections on lateral buckling of thin-walled beams

  • Mohri, F.;Potier-Ferry, M.
    • Steel and Composite Structures
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    • v.6 no.5
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    • pp.401-415
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    • 2006
  • Based on a non-linear model taking into account flexural-torsional couplings, analytical solutions are derived for lateral buckling of simply supported I beams under some representative load cases. A closed form is established for lateral buckling moments. It accounts for bending distribution, load height application and pre-buckling deflections. Coefficients $C_1$ and $C_2$ affected to these parameters are then derived. Regard to well known linear stability solutions, these coefficients are not constant but depend on another coefficient $k_1$ that represents the pre-buckling deflection effects. In numerical simulations, shell elements are used in mesh process. The buckling loads are achieved from solutions of eigenvalue problem and by bifurcations observed on non linear equilibrium paths. It is proved that both the buckling loads derived from linear stability and eigenvalue problem lead to poor results, especially for I sections with large flanges for which the behaviour is predominated by pre-buckling deflection and the coefficient $k_1$ is large. The proposed solutions are in good agreement with numerical bifurcations observed on non linear equilibrium paths.