• 대한지리학회지
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• 제47권3호
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• pp.315-327
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• 2012

한반도 남서부에 위치한 영암 일대의 화강암 구릉대에는 적색의 지표피복물들이 일반화되어 나타나고 있으며, 이를 고온다습한 고기후의 산물로써 성대토 개념으로 간주되어 왔다. CIA와 A-CN-K, A-CNK-FM 도식을 이용하여 이들 적색의 풍화층이 지니는 화학적 풍화 특색을 살펴본 결과, 모암에서 사장석이 완전 풍화에 준하는 수준의 강한 화학적 풍화가 일어남으로써 사질의 풍화층이 형성되었고, 풍화층이 형성된 이후로는 칼륨 장석의 용탈에 의해 풍화층의 화학적 변화가 일어나고 있는 상태이다. 그러나 일라이트와 같은 일차 광물의 수준을 넘어서지 못한 상태에 있으며, 라테라이트 단면에서 나타나는 카올리나이트와 같은 2차 광물로의 화학적 풍화는 진전되지 못한 상태이다. 화학적 풍화의 결과로서 알칼리 성분들은 용탈에 의해 함량이 낮아진 상태이지만, 철분과 마그네슘 같은 유색 광물들은 상대적으로 미약한 용탈이 발생하여 풍화층의 적색화가 이루어지고 있는 것으로 판단된다.

• 약학회지
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• 제52권1호
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• pp.20-26
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• 2008

2-Aminothiazole ring as a bioisoster of catechol in dopamine has provided with good oral availability and lipophilic property. Selenium was reported to have an improved antioxidant ability and to reduce the loss of dopamine. 2-Aminoindan, is a rigid form of dopamine, was evaluated as a dopamine agonist with low neurotoxocity. In order to develop a novel dopamine agonist, we tried to synthesize the selenazoloaminoindan derivative that is a hybrid structure of aminoindan and aminoselenazole instead of aminothiazole. 2-Indanone-2-oxime was reduced with $TiCl_4$ and $NaBH_4$ to form 2-aminoindan, which was reacted with propionyl chloride to give 2-N-n-propionylaminoindan (2). Compound 2 was reduced with $TiCl_4$ and $NaBH_4$ to afford 2-N-n-propylaminoindan (3) and it was nitrated and reduced to form 5-amino-2-N-n-propylaminoindan (5), which was reacted with KSeCN, $Br_2$, and glacial acetic acid to give 4,6-dibromo-5- amino-2-N-n-propylaminoindan (7) instead of selenazole ring formation. Otherwise, compound 2 was nitrated and hydrogenated to form 5-amino-2-N-n-propionylaminoindan (9), which was treated with KSeCN, $Br_2$, and glacial acetic acid to give 4,6-dibromo-5-amino-2-N-n-propionylaminoindan (10). Compound 9 was cyc1ized with KSeCN and glacial acetic acid in the absence of $Br_2$ to give 6-amino-2-N-(n-propionylamino)selenazolo[4,5-f]indan (11).

• 한국식품위생안전성학회지
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• 제26권1호
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• pp.76-81
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• 2011

The protease produced by a Bacillus pumilus CN8 strain was purified by DEAE-Cellulose-52 ion exchange. It has a molecular weight of approximately 96,920 Dalton. In the present study, this protease showed strong activity over a broad range of pH (6.5-9.5) and temperature from $40^{\circ}C$ to $60^{\circ}C$, and the protease performed the maximal activity at pH 7.3 at $42^{\circ}C$. The effect of metal ions on protease activity showed that $K^+$ could slightly increase the protease activity, and other ions such as $Zn^{2+}$, $Fe^{2+}$, $Na^+$, $Ca^{2+}$, $Mg^{2+}$ had no significant activation or inhibition to the protease (P> 0.05), and the more important is that $Cu^{2+}$, $Mn^{2+}$, $Sn^{2+}$, $Cd^{2+}$ had a strong inhibitory effect on the protease activity.

• 한국식품영양학회지
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• 제10권1호
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• pp.6-13
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• 1997

여러 종류의 coumarin 유도체가 광화학 반응에 의하여 OH·라디칼을 생성하는 반응을 ESR 및 레이저 섬광분해 반응으로 진행시키고 반응속도 상수를 구하여 반응성가 메카니즘을 알아보았다. 본 연구에서 사용된 9종류의 coumarin 유도체는 모두 OH·라디칼 생성반응 메카니즘으로 반응이 진행되었으나 1-ethy1-3-nitro-1-nitrosoguanidine은 광조사에 의해 OH·라디칼 생성반응이 일어나기 전에 분해하여 카르벤 중간체로 변하였다. 9개의 coumarin 유도체는 DMPO-OH 스핀부가 생성물에 해당하는 시그날을 나타내었다. OH·라디칼을 소진시키는 NaN3, EtOH, HCOONa 등은 강한 광증감제로 작용하였다. 수화된 전자의 소멸 THRE 상수는 N20을 첨가했을 때가 K3Fe(CN)6을 첨가했을 때보다 크게 나타났다.

• 천문학회지
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• 제38권2호
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• pp.215-218
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• 2005

An atlas of high resolution (${\lambda}/{\Delta}{\lambda}$=45,000) profiles of interstellar atomic lines of K I (7665, 7699 ${\AA}$), Na I (D 1, D2), Ca II (H, K), Ca I (4227 ${\AA}$), molecular structures of CH, CH+, CN and the major diffuse interstellar bands at 5780 and 5797 ${\AA}$ based on ${\~}$300 echelle spectra of ${\~}$200 OB stars is presented. Relationships between the reddenings, distances and equivalent widths of NaI, CaII, KI, CH, CH+, CN and diffuse bands are discussed. The equivalent width of K I (7699 ${\AA}$) as well as of CH4300 ${\AA}$ / correlate very tightly with E(B- V) in contrast to the features of neutral sodium, ionized calcium and the molecular ion CH+. The equivalent widths of the Hand K lines of Call grow with distance at a rate ${\~}$250m${\AA}$ per 1 kpc. A similar relation for NaI is much less tight. The strengths of neutral potassium lines, molecular features and diffuse interstellar bands do not correlate practically with distance. These facts suggest that ionized calcium fills the interstellar space quite homogeneously while the other carriers mentioned above, especially K I, CH and these of diffuse bands occupy more and more compact volumes, also filled with dust grains. Apparently the carriers of narrow diffuse bands are spatially correlated with simple molecules and dust grains - all abundant in the so-called 'zeta' type clouds. The same environment seems to be hostile to the carriers of broad diffuse interstellar bands (DIEs) (like 5780 or 6284) and -to a certain extent - also to CaII, NaI and CH+.

• Toxicological Research
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• 제26권2호
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• pp.117-121
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• 2010

The crude ethanol extract of B. repanda showed the cytotoxic activity against Polio virus (25% activity at $150{\mu}g$/disk) and the minor cytotoxic activity against BSC cells (African green monkey kidney). However, the crude ethanol extract of B. repanda was non-toxic to murine leukaemia cells CCL 46 P388D1 ($IC_{50}$, > 62,500 ng/ml). Cytotoxic and antifungal activities were strongly shown by Fr. 64-3 which was eluted with 90% $CH_3CN/H_2O$, 100% $CH_3CN$, and 50% $CH_3CN/H_2O$(SM 2 at $150{\mu}g$/disk). The fraction 64-3 also showed the most cytotoxic activity against murine leukaemia cells (128 mg, $IC_{50}$ 10,051 ng/ml at $75{\mu}g$/disk). These results suggest that this fraction has a potent antifungal activity against the dermatophytic fungus Trichophyton mentagrophytes ATCC 28185.

• 한국지형학회지
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• 제27권3호
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• pp.1-11
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• 2020

A CIA analysis (A-CN-K and A-CNK-FM ternary diagram) indicates that, unlike the general granitic hills of the Korean Peninsula, the chemical weathering of the granitic grus (sandy regolith) in the eastern Jincheon basin is variable in geomorphic site except the Chuncheon basin. In the study area, there are three types of hills, such as; inner hills, linear isolated hills, and outer hills. The weathered mantles of the outer hills and linear isolated hills are weakly altered, whereas the inner hill, the Bonghyeon profile, shows a stronger chemical loss of the compositions approximating saprolite. There are small differences between the outer hills and linear isolated hills. The Geumwang site is considered fresh rock due to a low lever of alteration, although its sampling profile shows sandy weathering mantles. In the profiles of the Masan and Mugeuks sites, the lower part of weathering mantles has not experienced a significant level of component loss, but the upper regoliths have substantially been modified. The alteration of the hills occurs by chemical loss of CaO and Na₂O. K₂O exhibited little variation at all sampling suites and it has not changed into saprolite.

• The Korean Journal of Physiology
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• 제1권2호
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• pp.141-150
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• 1967

The present investigation was initially undertaken to see if there exists $Na^+-K^+$ activated ATPase in the microsome fraction of the kidney. Having confirmed the presence of such an enzyme, further attempts have been made to characterize its nature and the following conclusions were obtained: (1) The ATPase activity was greatest at the $Na^+$ concentration of 100 mM as well as at $K^+$ concentration of 10 mM. Moreover, the ATPase activity was found to be depressed by $Ca^{++}$ in the presence of $Mg^{++}$. (2) While the ATPase activity was depressed by Ouabain, the magnitude of inhibition was greater in the Na medium than in the K medium. (3) NaCN augmented the ATPase activity whereas NaF and IAA depressed it. On the other hand, DNP had little influence on the ATPase activity. (4) Diamox, vasopressin and aldosterone had no effect while $HgCl_2$ markedly depressed the ATPase activity These findings indicate that the nature of ATPase isolated from the microsome fraction of the rabbit kidney is quite similar to that from other organs such as the heart and the muscle, although there are certain features specific to the type of organs.

• Toxicological Research
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• 제5권1호
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• pp.27-35
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• 1989

When acetaminophen (25mM) was introduced into the perfused rat liver, the hepatic O2 uptake was rapidly inhibited first and then later slow-down. The rapid inhibition was found to be due to mitochondrial blockade, whereas the so-called slow inhibition" was associated with microcirulatory aberrations as evidenced by inhomogneous staining of the liver tissue by trypan blue infusion (0.1%). NaCN (0.5mM) also caused rapid and slow respiratory inhibitions, giving heterogeneous trypan blue staining.ning.

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2008년도 Asian Magnetics Conference
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• pp.169.2-169.2
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• 2008