• 제목/요약/키워드: NSDD

검색결과 7건 처리시간 0.022초

Single Nucleotide Polymorphisms of NLRP12 Gene and Association with Non-specific Digestive Disorder in Rabbit

  • Liu, Yun-Fu;Zhang, Gong-Wei;Xiao, Zheng-Long;Yang, Yu;Deng, Xiao-Song;Chen, Shi-Yi;Wang, Jie;Lai, Song-Jia
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제26권8호
    • /
    • pp.1072-1079
    • /
    • 2013
  • The NLRP12 (NLR family, pyrin domain containing 12) serves as a suppressor factor in the inflammatory response and protects the host against inflammation-induced damage. In the present study, we aimed to study the polymorphisms of NLRP12 gene and its association with susceptibility to non-specific digestive disorder (NSDD) in rabbits. We re-sequenced the entire coding region of the rabbit NLRP12 gene and detected a total of 19 SNPs containing 14 synonymous and five non-synonymous variations. Among them, the coding SNP (c.1682A>G), which would carry a potential functional implication, was subsequently subjected to genotyping for case-control association study (272 cases and 267 controls). The results revealed that allele A was significantly protective against NSDD with an odds ratio value of 0.884 (95% confidence interval, 0.788 to 0.993; p = 0.038). We also experimentally induced NSDD in growing rabbits by feeding a fibre-deficient diet and subsequently investigated NLRP12 mRNA expression. The mRNA expression of NLRP12 in healthy status was significantly higher than that in severe NSDD (p = 0.0016). The highest expression was observed in individuals carrying the protective genotype AA (p = 0.0108). These results suggested that NLRP12 was significantly associated with the NSDD in rabbits. However, the precise molecular mechanism of NLRP12 involving in the development of rabbit NSDD requires further research.

불용성 오손물에 의한 절연물의 전기적 특성에 관한 연구 (The Electric Properties of Insulators Due to Mon-soluble Contaminant)

  • 한상옥;장태인;강지원;조성배
    • 대한전기학회:학술대회논문집
    • /
    • 대한전기학회 2000년도 하계학술대회 논문집 C
    • /
    • pp.1785-1787
    • /
    • 2000
  • This paper present the result of the investigation, the electric properties of insulators due to non-soluble contamination. In general, the humidity and the amount of soluble salts such as NaCl, $MgCl_2$ are the most dominant factor. Though the non-soluble do not distribute on conductivity of contaminant layer, that has the hygroscopic property. For this study, we make a mini-fog chamber with transparent acryl and the kaoline was used for non-soluble contaminant. The kaoline was applied with sprayer to get the specific ESDD and NSDD value, then the specimen was dried and installed horizontally. And to measure the leakage current a DAS system was developed with LabView. With the result, we could know the influence of non-soluble content and the relationship between NSDD and ESDD.

  • PDF

오손조건에 따른 옥외절연물의 전기적 특성 (Electrical Properties of Outdoor Insulator with the Difference of Contaminated Condition)

  • 최남호;구경완;박강식;한상옥
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 2000년도 추계학술대회 논문집
    • /
    • pp.467-470
    • /
    • 2000
  • This paper present the result of the investigation, electric properties of outdoor insulators with the difference of contaminated condition. In general, the humidity and the amount of soluble salts such as NaCl, MgCl$_2$are the most dominant factor. A mini-fog chamber with transparent acryl and the standard contamination solution with kaoline was used. The kaoline was applied with sprayer to get the specific ESDD and NSDD value, then the specimen was dried and installed horizontally. And to measure the leakage current and the ambient condition, such as relative humidity and temperature, a DAS system was developed with LabView. From the result, we could know the influence of contaminated condition. Contaminated area and pattern has a close relationship with the electrical properties of outdoor insulator.

  • PDF

불용성 오손물에 의한 절연물의 전기적 특성에 관한 연구 (The Electric Properties of Insulators Due to Non-soluble Contaminant)

  • 최남호;국연호;조성인;박강식;한상옥
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 2000년도 하계학술대회 논문집
    • /
    • pp.691-695
    • /
    • 2000
  • This paper present the result of the investigation, the electric properties of insulators due to non-soluble contamination. In general, the humidity and the amount of soluble salts such as NaCl, MgCl$_2$are the most dominant factor. Though the non-soluble do not distribute on conductivity of contaminant layer, that has the hygroscopic property. For this study, we make a mini-fog chamber with transparent acryl and the kaoline was used for non-soluble contaminant. The kaoline was applied with sprayer to get the specific ESDD and NSDD value, then the specimen was dried and installed horizontally. And to measure the leakage current a DAS system was developed with LabView. With the result, we could know the influence of non-soluble content and the relationship between NSDD and ESDD.

  • PDF

초고압애자의 ESDD 및 NSDD 측정을 통한 내환경 특성 연구 (A Study on Environmental Characteristic of Insulators for Ultra High Voltage Using ESDD and NSDD Measurement)

  • 이상윤;임윤석;이원교;이동일;신구용
    • 대한전기학회:학술대회논문집
    • /
    • 대한전기학회 2009년도 제40회 하계학술대회
    • /
    • pp.2095_2096
    • /
    • 2009
  • 송배전용 설비에 사용되는 애자의 신뢰성은 전기적인 절연성질과 기계적인 내구성 뿐만 아니라 애자가 설치된 송전선로의 오손에 의한 내환경성에 의해서도 결정될 수 있다. 지금까지 염분 및 분진이 심한 지역에서 오손물이 애자에 미치는 영향에 대한 연구는 전기적, 기계적 신뢰성에 영향을 미치는 오손물질의 성분 분석 등을 통해 저압과 고압의 환경에서 진행되어 왔다.[1] 본 논문에서는 2003년부터 우리나라에서 운전해 오고 있는 765kV 애자오손 신뢰성 검토와 미국 전력연구원(EPRI)에서 수탁받은 765kV 고분자애자 특성연구의 일환으로, 765kV 상용선로에 사용되는 애자류에 대한 장기열화특성을 연구하기 위해 765kV 실증 시험설비를 구축하였다. 아울러, 765kV 애자 장기열화특성 분석을 위한 기초연구로 염분 및 분진 오손도를 측정하여 765kV 환경에서 애자종류에 따른 오손 특성을 검토하였다. 그 결과, RTV 실리콘고무 코팅 애자가 자기 및 유리재 애자에 비해 염분 오손도 면에서 비교적 우수한 특성을 지님을 확인 할 수 있었다.

  • PDF

불용성 오손물을 이용한 오손주기시험법 (Pollution Cycle Method with NSDD Contaminant)

  • 이원영;최남호;박상식;한상옥
    • 대한전기학회:학술대회논문집
    • /
    • 대한전기학회 2001년도 하계학술대회 논문집 C
    • /
    • pp.1481-1483
    • /
    • 2001
  • There is a wide climatic difference between Korea and foreign countries. Thus, the pollution cycle method, based on the climatic condition of Korea, is needed to evaluate the electrical properties of outdoor insulators. We make a analysis on the cycle methods of foreign countries, climatic conditions of Korea and failure data to make the cycle method. From the result, we can design a good pollution cycle method to evaluate the electrical properties of outdoor insulators.

  • PDF

오손조건에 따른 애자의 섬락 특성에 관한 연구 (A Study on the Flashover Properties of Insulators with Artifitial Pollution)

  • 송치훈;조성인;국연호;남궁도;한상옥
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 2000년도 하계학술대회 논문집
    • /
    • pp.679-682
    • /
    • 2000
  • This paper present the result of the flashover properties of inulators due to artifitial pollution. For this study, a mini fog chamber has been fabricated with transparent acryl which has the merit in observasion and electrical insulation. All the experiment was carried in mini fog chamber. Though non-souble contaminant do not distribute on the electric conductivity of contaminant and contaminated insulator, that influence on the flashover characteristics of insulators. with the result, we assume phenomenon caused with the hygroscopic property of non-soluble contaminant.

  • PDF