• 국제학술발표논문집
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• The 1th International Conference on Construction Engineering and Project Management
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• pp.424-428
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• 2005

As the application of NPM in waste administration branch this paper proposes a new waste management method in order to increase the efficiency of resources and reduce the quantity of waste. First the matrix method is suggested which comprehensively consider and integrate the proposals of different government departments. Moreover the inhabitant's attitude toward the new waste management measures was investigated. Based on the investigation the evaluation function was made, which include three elements: necessary budget, the effect of cost decrease and the environmental burden decrease. The optimal method of budget allocation to maximize social welfare is proposed under the condition of limited budget by the evaluation function. By applying this system further local governments will be able to determine their adequate service level and budget size.

• 대한의용생체공학회:의공학회지
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• 제23권3호
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• pp.253-261
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• 2002

양전자방출단층촬영기(Positron emission tomography, PET) 영상 개선을 위하여 적응적 공간 필터를 개발하였으며. 개발한 필터의 성능을 시뮬레이션데이터. 모형 PET 영상과 환자 PET 영상을 이용하여 평가하였다. 경계화소로 검출된 화소와 윈도우내의 모든 화소값이 동일한 화소는 보존하고. 그 외 화소에 대하여 2:7:2 비율로 가중치를 주어 정열한 후 중앙의 9개 화소에 대한 평균값으로 대치하였다. 경계화소를 검출하기 위하여 두 개의 임계값(TH7, TH2)을 이용하였으며. 다음의 조건을 만족하면 경계화소로 판단하였다 . THl ($pix_max{\times}0.1/log_2(NPM)$, NPM :주변값중 최상위 값과 최하위 값을 제외한 주변값들의 평균) 보다 작은 ADs (중앙값과 주변값의 차에 대한 절대값) 개수는 8-k이고. TH2 ($NPM{\times}0.1$) 보다 큰 ADs 개수는 k. 여기서 k는 2, 3 ‥‥ 6의 값을 가진다 성능평가 결과 이 연구에서 제안한 필터가 가우시안 필터, 가중메디안 필터, 부분집합평균메디안 필터 등과 비교하여 우수한 성능을 제공하는 것을 관찰하였다. 본 논문에서 개발한 간단한 적응적 공간 필터는 공간 분해능 저하는 최소화하면서 균일도와 대조도를 향상시키는데 효과적 이여서 정확한 PET 영상 해석에 기여할 것으로 기대된다

• The Journal of Asian Finance, Economics and Business
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• 제7권12호
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• pp.739-748
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• 2020

The study aims to estimate the effect of current ratio (CR), current liability to inventory (CLI), total asset turnover (TAT), net profit margin (NPM), sales growth (SG), and company size (FS) on profit growth (PG). The research population was 18 companies in the Food and Beverage (F&B) sector listed on the Indonesia Stock Exchange (IDX) from 2014-2018. The data estimation method uses the common effect panel data regression model. The empirical findings show that the CR and CLI ratios have a negative effect on PG, while the TAT, NPM, and SG ratios have a positive effect. Company size is a factor that does not affect the growth of company profits. The results of the study imply that an increase in company profits can be achieved if the company operates efficiently and with low liquidity to encourage higher sales growth. The limitations of the research are as follows: first, this research considers only one type of industry, hence the results of this study would not be the same if applied to another type of industry. Second, the author observes profit growth by using the company's financial ratios and size and ignores other factors that may affect profit growth, for example, the number of employees, total net sales, and market capitalization.

• 산경연구논집
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• 제5권2호
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• pp.13-20
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• 2014

Purpose - The purpose of this study is to empirically investigate the impact of capital structure on firm performance. Research design, data, and methodology - This study examined the impact of capital structure on the performance of cement companies listed on the Karachi Stock Exchange during the period 2009-2013. The authors hypothesize that there is a negative relationship between capital structure and firm performance. To examine the association, the authors run a Pearson correlation and multiple regression analysis. Results - Results reveal a strong negative relationship between debt to asset and firm performance variables (GPM, NPM, ROA, and ROE). Further, there is a positive relationship between debt to equity and firm performance variables (GPM and NPM), anda negative relationship between debt to equity and firm performance variables (ROA and ROE). Moreover, capital structure variables significantly impact firm performance. Conclusions - This study concluded that financial analysts and managers should emphasize on the optimal level of capital structure and efficient utilization and allocation of resources to achieve the targeted level of productive efficiency in business.

• Genomics & Informatics
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• 제11권1호
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• pp.34-37
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• 2013

This study evaluated the effects of somatic mutations and single nucleotide polymorphisms (SNPs) on disease progression and tried to verify the two-hit theory in cancer pathogenesis. To address this issue, SNP analysis was performed using the UCSC hg19 program in 10 acute myeloid leukemia patients (samples, G1 to G10), and somatic mutations were identified in the same tumor sample using SomaticSniper and VarScan2. SNPs in KRAS were detected in 4 out of 10 different individuals, and those of DNMT3A were detected in 5 of the same patient cohort. In 2 patients, both KRAS and DNMT3A were detected simultaneously. A somatic mutation in IDH2 was detected in these 2 patients. One of the patients had an additional mutation in FLT3, while the other patient had an NPM1 mutation. The patient with an FLT3 mutation relapsed shortly after attaining remission, while the other patient with the NPM1 mutation did not suffer a relapse. Our results indicate that SNPs with additional somatic mutations affect the prognosis of AML.

• The Journal of Asian Finance, Economics and Business
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• 제7권11호
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• pp.101-106
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• 2020

The research was conducted with the aim of knowing the effect of the CAMELS ratio either partially or simultaneously on stock prices. The CAMELS ratio (Capital, Asset Quality, Management, Earning, Liquidity) is used to measure the soundness of a bank, where by the better the soundness of the bank, the more profitable the bank will be for potential investors and other interested parties. The population of this research consists of the four state banks documented on the Indonesia Stock Exchange over the 2012-2019 period. The sample selection technique is a saturated sampling. This study provides the results that partially CAR has a significant effect on the share price of government banks listed on the IDX. Meanwhile, NPL, NPM, ROA, and LDR do not have a significant effect on stock prices of state banks listed on the IDX. The results of the regression analysis show that, together the CAMELS ratio, which is proxied by CAR, NPLS, NPM, ROA, and LDR has a positive and significant influence on the share price of state-owned banks documented on the Indonesia Stock Exchange, so this can be used as a reference for investors in predicting the share price of a state-owned bank before investing in shares.

• The Journal of Asian Finance, Economics and Business
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• 제7권10호
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• pp.751-759
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• 2020

This study examines the impact of mergers on the financial performance of the Jordanian public shareholding companies. The study employs data collected for a sample of 10 Jordanian non-financial public firms that were engaged in legal horizontal merger deals between 2000 and 2013. The data was collected from the published annual financial reports of the merging companies and comparative companies for three years before the merger and three years after the merger. Event study methodology was applied to examine the data. Four measures of financial performance (FP) were used, which are return on assets (ROA), return on equity (ROE), earnings per share (EPS), and net profit margin (NPM). Two methods were used in the analysis - the change model and the intercept model using financial performance raw data and industry-adjusted data. The findings in general showed no significant impact of mergers on the financial performance of merging firms using the change model. However, by using the intercept model, significant impact of mergers on the financial performance was found on the sample of the study. The significant impact was found for mergers on the raw ROE of the merging firms, and on the ROA and NPM of the industry-adjusted firms.

• Asian Pacific Journal of Cancer Prevention
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• 제15권3호
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• pp.1247-1253
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• 2014

Mutations in the DNMT3A and IDH genes represent the most common genetic alteration after FLT3/NPM1 in acute myeloid leukemia (AML). We here analyzed the frequency and distribution pattern of DNMT3A and IDH mutations and their associations with other molecular markers in normal karyotype AML patients. Fortyfive patients were screened for mutations in DNMT3A (R882), IDH1 (R132) and IDH2 (R140 and R172) genes by direct sequencing. Of the 45 patients screened, DNMT3A and IDH mutations were observed in 6 (13.3%) and 7 (15.4%), respectively. Patients with isolated DNMT3A mutations were seen in 4 cases (9%), isolated IDH mutations in 5 (11.1%), while interestingly, two cases showed both DNMT3A and IDH mutations (4.3%). Nucleotide sequencing of DNMT3A revealed missense mutations (R882H and R882C), while that of IDH revealed R172K, R140Q, R132H and R132S. Both DNMT3A and IDH mutations were observed only in adults, with a higher frequency in males. DNMT3A and IDH mutations were significantly associated with NPM1, while trends towards higher coexistence with FLT3 mutations were observed. This is the first study to evaluate DNMT3A/IDH mutations in Indian patients. Significant associations among the various molecular markers was observed, that highlights cooperation between them and possible roles in improved risk stratification.

• 국제지역연구
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• 제14권3호
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• pp.57-80
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• 2010

이 연구에서는 개방형 정책조정방법이 사회적 포용의 영역에 도입된 이후, 과정의 변화와 정책효과에 대한 평가를 시도한다. 2000년 리스본이사회에서 결정된 개방형 정책조정방법의 정책도구들은 결과지향적인 신공공관리론과 과정지향적인 숙의적 다중질서라는 거버넌스이론을 배경으로 한다고 볼 수 있다. 역사적 변화과정을 살펴볼 때 결과지향적인 신공공관리론의 정책도구인 목표설정, 수범사례의 벤치마킹, 분권적 의사결정의 경우 애매하거나 아예 거부되었고, 제도적 틀을 넘지 못함으로써 효율성을 추구할 수 없었다. 아울러 규범적인 숙의적 다중질서이론이 제시하는 것처럼 학습을 위해 숙의와 상호검토를 추구하고 있으나, 실제 운영은 성찰적인 숙의과정에 미치지 못하고, 상호검토도 제도적 한계를 보임으로써 원활한 학습이 이루어지지 않는다. 10여 년간 개방형 정책조정방법이 집행되었지만 정책효과의 측면에서도 유의미한 결과를 찾을 수 없다. 그렇지만 빈곤문제에 대한 인식이 변하고 시민사회가 활발하게 조직되어 참여가 확대되고 있는 점은 긍정적인 효과이다.

• 디지털융복합연구
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• 제6권2호
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• pp.23-32
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• 2008

This paper tried to discuss response of local government facing governance era. Governance is intended to introduce a variety of residents' participating systems to revive the citizen's society and strengthen the foundation for that purpose, thus seeking the paradigm for decentralized operation of the nation. As widely accepted, governance has many meanings connected with controling method of interdependence activity. However bureaucracy do not make decisions as one-side and vertical like past but is form of public decisions that stakeholder in policy. Firstly, we reviewed the terms of governance and policy issues and policies on governance. And also survey on actual performer associated with governance in Gumi. Next, proposals of the development of policy in governance, role of local government are made in terms of construction of governance.