• 정신신체의학
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• 제27권2호
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• pp.155-163
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• 2019

연구목적 본 연구의 목적은 알츠하이머형 치매 및 경도인지장애 환자에서 내측두엽 위축 정도의 차이에 따른 중증도, 신경인지기능 및 행동심리증상을 비교하는 것이다. 방 법 본 연구는 단면 연구로서, 알츠하이머형 치매 및 경도인지장애로 진단받은 114명을 대상으로 하였다. 내측두엽 위축은 표준화된 시각 기반 척도(Scheltens scales)에 의해 평가되었으며, 대상군은 두 그룹으로 분류되었다. 중증도는 임상치매평가척도(Clinical dementia rating, CDR)와 전반적 퇴화 척도(Global deterioration scale, GDS)로 평가되었으며 신경인지기능은 한국어판 간이 블레스드 검사(The Korean version of the short blessed test, SBT-K), 한국형 CERAD (The Korean version of the consortium to establish a registry for Alzheimer's disease, CERAD-K), 행동심리증상은 한국형 신경정신행동검사(The Korean version of the Neuropsychiatric Inventory, K-NPI)로 평가되었다. 내측두엽 위축의 정도에 따른 중증도와 신경인지기능 및 행동심리증상의 차이를 분석하기 위해 독립표본 t-test를 시행하였다. 결 과 내측두엽 위축의 중증도가 높은 군은 낮은 군에 비하여 CDR, SBT-K, 그리고 CERAD-K의 하부항목 중 네가지 항목에서 유의하게 낮은 점수를 보였다(p<0.05). 결 론 내측두엽 위축과 중증도 및 신경인지기능 사이에는 유의한 양의 상관관계가 나타났으나 행동심리증상과는 유의한 상관관계가 나타나지 않았다. 내측두엽 위축의 평가는 인지장애의 진단과 치료에 잠재적 이점을 제공할 것으로 생각된다. 행동심리증상과 뇌구조의 연관성에 대해서는 추가적인 연구가 필요할 것으로 보인다.

• 한국산학기술학회논문지
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• 제17권5호
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• pp.459-469
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• 2016

본 연구는 요양시설 치매노인의 치매유형에 따른 행동심리증상 특성과 간호제공자의 업무 부담감 정도 차이를 파악하고자 시도되었으며, 자료 수집은 2014년 6월 1일부터 12월 31일까지 5개 노인요양시설에서 실시하였다. 총 214명(알츠하이머형 치매노인 131명, 혈관성 치매노인 83명)이 연구에 참여하였으며, 행동심리증상 특성과 간호제공자의 업무 부담감은 NPI-NH (Neuropsychiatric Inventory Nursing Home Version)를 활용하여 측정하였다. 연구 결과, 알츠하이머형 치매군과 혈관성 치매군 모두에서 무감동/무관심의 발생빈도가 가장 높았으며, 알츠하이머형 치매군이 혈관성 치매군에 비하여 불안, 들뜬 기분/다행감, 과민/불안정의 발생빈도가 유의하게 높았다. 전체 행동심리증상 점수는 알츠하이머형 치매군과 혈관성 치매군에서 유의한 차이가 없었으나, 세부영역에서 초조/공격성 점수는 알츠하이머형 치매군이 혈관성 치매군보다 유의하게 높았다. 전체 간호제공자의 업무 부담감은 알츠하이머형 치매군이 혈관성 치매군보다 유의하게 높았고, 특히, 알츠하이머형 치매군에서 초조/공격성의 업무 부담감 부분이 의미 있게 높았다. 결론적으로 요양시설 치매노인은 치매유형에 따라 행동심리증상정도에 차이가 있으므로 차별화된 간호가 필요하며, 간호제공자의 업무 부담감 감소를 위한 다양한 프로그램 개발 및 전략이 필요한 것으로 사료된다.

• 한국심리학회지 : 문화 및 사회문제
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• 제21권3호
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• pp.377-394
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• 2015

본 연구는 자기애성 성격과 성폭력 가해 행동의 관계, 그리고 이 둘 간을 매개 또는 조절하는 심리적 변인들을 확인하여, 성폭력 범죄에 대한 효과적인 치료 방법 개발과 교육 및 예방에 기여하고자 하였다. 강원대학교 남학생 264명에게 자기애적 성격 검사(NPI), 병리적 자기애 검사(PNI), Hendrick 다차원적 성태도 질문지(MSAS), 인지적 정서조절 전략 질문지(CERQ), 아동성폭력범 공감척도(CMEM), 성폭력 가해 행동 질문지를 실시하였다. 위계적 회귀분석을 이용하여, 특권분노와 허용적 성태도의 매개효과와 인지적 정서조절 전략과 상태공감의 조절효과를 검증하였다. 위계적 회귀분석 결과, 특권분노의 매개효과와 인지적 정서조절 전략의 조절효과는 나타나지 않았지만, 허용적 성태도의 매개효과와 상태공감의 조절효과는 유의미하였다. 이는 허용적 성태도가 성폭력의 원인이 될 가능성이 높고, 상태공감이 낮은 경우에 자기애가 높으면 성폭력이 급격히 증가한다는 것을 의미한다. 구체적으로, 자기애가 높은 경우에 상태공감이 낮을 때는 성폭력이 높게 나타났지만, 자기애가 높더라도 상태공감이 높다면 성폭력이 낮은 것으로 밝혀졌다. 이는 낮은 상태공감이 성폭력에 대한 위험요인으로 작용하는 반면, 높은 상태공감은 성폭력에 대한 보호요인임을 의미한다. 본 연구의 결론을 요약하면 다음과 같다. 성폭력 가해 행동의 원인은 특권분노보다는 허용적인 성태도에 의한 것일 가능성이 높다. 또한, 성폭력에 대한 치료적 개입에는 정서조절 훈련에 비해 상대적으로 상태공감을 증가시킬 수 있는 훈련이 더 효과적이라고 할 수 있다. 논의에서 보다 자세한 결론과 시사점 및 제한점을 제시하였다.

• 노인정신의학
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• 제16권1호
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• pp.24-30
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• 2012

Objectives : The purpose of this study was to compare the efficacy of galantamine treatment, especially attention ability between patients with pure Alzheimer's disease (AD) and Mixed dementia (MD) during a 24-week trial. Methods : A total of 40 patients were recruited for this 24-week study. The effect of galantamine on attention was measured using Seoul Computerized NeuroCognitive Function Test (SCNT) and frontal functions test of Seoul Neuropsychological Screening Battery (SNSB). Patients'activities of daily living using the Seoul-Activities of Daily Living (S-ADL) and the Seoul-Instrumental Activities of Daily Living (S-IADL) ; behavioral symptoms using the Korean version Neuropsychiatric Inventory (K-NPI) were measured at baseline and 24-week. Results : 17 pure AD patients and 23 MD patients were analyzed in this study. Attention as measured by SCNT was not significantly different from baseline after 24 weeks of treatment in both groups. There was no significant difference between two groups in mean change from baseline in the SCNT, S-ADL, S-IADL and K-NPI scores at 24-week. Conclusion : Galantamine showed a therapeutic effect on cognition, activities of daily living, neuropsychiatric symptoms in pure AD and MD. Furthermore, Galantamine may specifically help to maintain attention and it may have positive effects on other cognitive and functional abilities.

• 보건의료산업학회지
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• 제9권3호
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• pp.255-266
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• 2015

Objective : The aim of this study was to examine the effects of the Home-based Multi-component Activity Program (Home-MAP) for the maintenance activities of daily living (ADL) for patients with mild Alzheimer's disease (AD) and on caregiver burden for caregivers. Methods : Nine mild AD patients and family caregivers. The Home-MAP was performed 1d/wk, for a total of 10 times over 10 weeks. Results : After the 10 sessions, participants' motor and process skills scores on the AMPS were found to have significantly improved (p=.028 and p=.028, respectively). The BPSD frequency score on the R-MBPC was found to be significantly reduced (p=.017). The BPSD symptoms related to caregiver reaction score on the R-MBPC and distress score on the NPI-Q were significantly reduced (p=.039 and p=.018, respectively). Conclusions : The Home-MAP appears to have contributed to the improvement of patients' capabilities in performing in ADL, to a reduction of BPSD, and to a reduction of burden related to BPSD.

• 대한물리의학회지
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• 제7권1호
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• pp.37-47
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• 2012

Purpose : The purpose of this study is to examine the effects of training in exercise rehabilitation on depressive emotion, behavioral and psychological symptoms(BPSD) caused by Alzheimer's disease elders. Methods : The subjects of this study were 34 patients with Alzheimer's disease over 65 and assigned randomly into one of two groups, each with 17 people. The experimental group was treated by training in exercise rehabilitation executed 60 minutes, 3 times a week for 8 weeks. The results of the experiment were analyzed using samples t-test along with averages and standard deviations as the statistical methods for data analyses. Results : The results of this study were as follows. First, the experimental group showed statistically significant improvements in the areas of depressive emotion(SGDS) compared to control group. Second, the experimental group showed statistically significant improvements in the severity of behavioral and psychological symptoms and subjective degrees of pain of care givers(NPI-Q) compared to control group. Conclusion : Based on the results of this study, training in exercise rehabilitation have an effect on depressive mood and BPSD in elderly with Alzheimer's disease.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.126-130
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• 1997

In the development of the totally implantable artificial heart (TAH), the information of the preload condition is important to ind appropriate condition or the automatic control of the heart. Our TAH configuration consists of two artificial ventricles, and brushless DC motor within actuator. The pressure between ventricles could indicate the preload condition during the TAH operation. If we can measure accurately inspite of the noise induced from TAH and environmental condition. We suggested integrating a feedback loop to remove an unexpected DC drift. NPI 19-series Nova sensor was used which could measure pressure in gas and liquid. This method and sensor enabled us to develop the pressure transducer compact so (that) the systems can be implanted with TAH into patient. This system has been verified in vitro and in vivo test. This results showed that the output waveform of this system was stable irrespective of animal condition.

• 한국펄프종이공학회:학술대회논문집
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• 한국펄프종이공학회 2006년도 PAN PACIFIC CONFERENCE vol.2
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• pp.325-329
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• 2006

Nippon Paper Industries, Co., Ltd. declared conversion of all the bleaching process to ECF, and most of the production had converted by now. To reduce ECF bleaching cost, we found that depending on electricity supply condition of the mill, utilization of ozone bleaching could be very effective. In addition, hot acid treatment of unbleached pulp also seemed to be effective for hardwood. In this study, several conditions for each technology were examined with the pulps from our own mills to reduce bleaching cost and to keep fiber quality acceptable level. In hot acid treatment study, with mild conditions (temperature lower than $90^{\circ}C$), sufficient reduction in Kappa number and hexenuronic acids content of the pulp were observed, while pulp viscosity was maintained. Moreover, to maintain strength of bleached pulp that subjected both to ozone bleaching and hot acid treatment, recommended Kappa number after ozone bleaching was more than 3. Based on these findings, two of our mills had installed medium-consistency ozone bleaching facilities and three mills installed hot acid treatment. Especially in Yatsushiro mill, both were installed in one bleaching line (A-ZD-E/P-D sequence), and running successfully.

• 한국산학기술학회논문지
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• 제13권11호
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• pp.5595-5600
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• 2012

본 논문은 poly(lactic acid)의 내열성을 향상시키기 위한 결정화 핵제의 검토 및 연구에 대한 것이다. 네 종류의 미세분말 핵제인 금속염 2,2'-methylene bis(4,6-di-tert-butylphenol) salt를 결정화 핵제로 사용하였다. 폴리머 컴파운드의 열적 및 기계적 특성은 DSC, HDT, UTM을 통해 측정하였다. 이 연구의 결과로서, 컴파운드 한 폴리머 샘플들의 내열특성은 핵제의 함량 증가와 미세분말 일수록 선형적으로 증가 하였다. 그 중에서MPZ2의 함량이 2 wt%일때 가장 높은 내열특성을 나타내었으며, PL98Z2 컴파운드의 열변형 온도는 $116^{\circ}C$를 나타내었다 (ASTM D 648, 0.455MPa).

• Child Health Nursing Research
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• 제1권1호
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• pp.5-15
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• 1995

The quality of mother-infant interaction during early postpartum period has a significant influence on the child growth and development in many aspects. The mother's initial perception of the newborns might have the lasting influence on the development of the mother-infant attachment and mother-infant relationship. Therefore the proper mother-infant interaction should be developed after infant birth. However, it is acknowledged that the high risk infants influence on the mothers' perception because of their abnormalities or disorders of physical condition and the restricted maternal contacts and interactions. The object of this study is to identify the difference of mother's perception of their normal and high-risk newborn during the early postpartum period. The ultimate goal is to contribute to use this basic data to develop nursing intervention toward the promotion of healthy mother-infant relationship and the helping of growth and development of children. The data were collected for this study from Sep. 21, 1990 to Oct. 1. 1991 at E University Hospital. The sample was 83 of mothers who had normal newborns and 73 mothers who had high risk newborns .The instrument was Neonatal Perception Inventory(NPI) designed by the Broussard for the measurement of mothers' perception of newborns about Average Baby and Your Baby. The data were analysed by using an SPSS Program and include percentage mean, SD, t-test, ANOVA. The results of this study are as follows : 1. The normal newborn mothers' perception is more positive than the high-risk newborn mothers(t=7.94, p=0.000). 2. Mothers' perception of the newborns is not related significantly to mothers' general characteristics. In conclusion, in order to promote positive, healthy mother-infant relationship, the nurse need to support, give information, and educate high-risk newborn mothers through early nursing assessment.