• Asian Pacific Journal of Cancer Prevention
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• 제16권18호
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• pp.8397-8403
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• 2016

Background: Breast cancer (BCa) is the most common malignancy in Mexican women. A set of histopathological markers has been established to guide BCa diagnosis, prognosis and treatment. Nevertheless, in only a few Mexican health services, such as that of the Secretariat of National Defense (SEDENA for its acronym in Spanish), are these markers commonly employed for assessing BCa. The aim of this study was to explore the association of Ki67, TP53, HER2/neu, estrogenic receptors (ERs) and progesterone receptors (PRs) with BCa risk factors. Materials and Methods: Clinical histories provided background patient information. Immunohistochemical (IHC) analysis was conducted on 48 tissue samples from women diagnosed with BCa and treated with radical mastectomy. The Chi square test or Fisher exact test together with the Pearson and Spearman correlation were applied. Results: On average, patients were $58{\pm}10.4$ years old. It was most common to find invasive ductal carcinoma (95.8%), histological grade 3 (45.8%), with a poor Nottingham Prognostic Index (NPI; 80.4%). ERs and PRs were associated with smoking and alcohol consumption, metastasis at diagnosis and Ki67 expression (p<0.05). PR+ was also related to urea and ER+ (p<0.05). Ki67 was associated with TP53 and elevated triglycerides (p<0.05), and HER2/neu with ER+, the number of pregnancies and tumor size (p<0.05). TP53 was also associated with a poor NPI (p<0.05) and CD34 with smoking (p<0.05). The triple negative status (ER-/PR-/HER2/neu-) was related to smoking, alcohol consumption, exposure to biomass, number of pregnancies, metastasis and a poor NPI (p<0.05). Moreover, the luminal B subty was associated with histological type (p=0.007), tumor size (p=0.03) and high cholesterol (p=0.02). Conclusions: Ki67, TP53, HER2/neu, ER and PR proved to be related to several clinical and pathological factors. Hence, it is crucial to determine this IHC profile in women at risk for BCa. Certain associations require further study to understand physiological/biochemical/molecular processes.

• 한국심리학회지 : 문화 및 사회문제
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• 제21권3호
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• pp.419-455
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• 2015

연구 1에서는 특정영역 위험감수 척도(Domain-Specific Risk Taking Scale)를 번안한 후, 대학생 438명에게 설문지를 실시하여 6요인 구조와 적절한 수준의 신뢰도와 타당도를 확인하였다. 연구 2에서는 연구 1과 다른 표집의 대학생 497명의 자료로 두 가지 연구문제를 탐구하였다. 첫째, NPI(Narcissistic Personality Inventory)와 PNI(Pathological Narcissism Inventory)로 측정한 자기애와 위험감수의 관계를 감각추구와 이득-위험지각이 매개하는지 알아보았다. 경로분석과 매개효과 검증결과 NPI자기애는 감각추구와 이득지각의 완전매개, PNI자기애는 감각추구와 이득지각의 부분매개를 통해 위험감수에 영향을 미치는 것으로 나타났다. 둘째, 이득-위험지각과 위험감수의 관계에서 조건부 자아가치감이 조절하는지 알아보았다. 다집단분석 결과 이득-위험지각이 위험감수 전체점수로 가는 경로에서 도덕성 조건부 자아가치감이 조절하는 것으로 나타났고, 위험감수의 6개 하위영역으로 가는 경로들에서는 조절효과를 보인 조건부 자아가치감의 하위유형들이 다양하게 나타났다. 이러한 결과를 이전의 위험감수연구와 비교하고 자기애 유형과의 관련성을 논의하였다.

• 대한간호학회지
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• 제24권4호
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• pp.557-567
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• 1994

The purpose of this study was to defined mothers perception of their infants when the babies were high - risk babies, and to describe the feelings and responses of the mothers following on the birth of high - risk babies and on their hospitalization. The subjects of the study were 30 mothers of high-risk infants at D and M Hospital of E University. Data were collected between August 1993 and June 1994. Using the Neonatal Perception Inventory(NPI ) devised by Broussard to determine the perception of mothers and an open-ended, semi-structured interview which was conducted in the nursery room within 24 to 72 hours after delivery And NPI tested 1 month after the babies were discharged from the NICU also. Data were analyzed using SAS and content analy-sis. The results of this study are as follows ; 1. The mothers tended to perceive their infants positively, regardless of the condition of the infant. Mothers who perceived their infant negatively were slightly increased at 1 month after the babies were discharged from the NICU, but the difference was not statistically significant. 2. Mothers reported that they thought that the newborn can see and hear well, and also they can ex-press themselves. 3. There were many types of response noted such as anxiety, fear, helplessness, pity, resentment, guilt, resignation, hope, relief, appreciation, and feelings of being able to overcome the situation. These were differentiated into positive and negative responses. The finding of positive responses being expressed by mother of high -risk infants while their infants were in NICU was a unique finding especially, appreciation and feelings of being able overcome the situation. The results suggest the need for replication studies and for research on nursing interventions directed at improving the quality of life of high-risk infants and their mother.

• Journal of Crop Science and Biotechnology
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• 제10권1호
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• pp.33-38
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• 2007

Nitrogen management at the panicle initiation stage(PI) should be fine-tuned for securing a concurrent high yield and high quality rice production. For calibration and testing of the recommendation models of N topdressing rates at PI for target grain yield and protein content of rice, three split-split-plot design experiments including five rice cultivars and various N rates were conducted at the experimental farm of Seoul National University, Korea from 2003 to 2005. Data from the first two years of experiments were used to calibrate models to predict grain yield and milled-rice protein content using shoot fresh weight(FW), chlorophyll meter value(SPAD), and the N topdressing rate(Npi) at PI by stepwise multiple regression. The calibrated models explained 85 and 87% of the variation in grain yield and protein content, respectively. The calibrated models were used to recommend Npi for the target protein content of 6.8%, with FW and SPAD measured for each plot in 2005. The recommended N rate treatment was characterized by an average protein content of 6.74%(similar to the target protein content), reduced the coefficient of variation in protein content to 2.5%(compared to 4.6% of the fixed rate treatment), and increased grain yield. In the recommended N rate treatments for the target protein content of 6.8%, grain yield was highly dependent on FW and SPAD at PI. In conclusion, the models for N topdressing rate recommendation at PI were successful under present experimental conditions. However, additional testing under more variable environmental conditions should be performed before universal application of such models.

• Journal of Preventive Medicine and Public Health
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• 제57권1호
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• pp.28-36
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• 2024

Objectives: This study investigated the impact of socioeconomic factors and sexual orientation-related attributes on the rates of coronavirus disease 2019 (COVID-19) vaccination and infection among men who have sex with men (MSM). Methods: A web-based survey, supported by the National Research Foundation of Korea, was conducted among paying members of the leading online portal for the lesbian, gay, bisexual, transgender, or queer and questioning (LGBTQ+) community in Korea. The study participants were MSM living in Korea (n=942). COVID-19 vaccination and infection were considered dependent variables, while sexual orientation-related characteristics and adherence to non-pharmacological intervention (NPI) practices served as primary independent variables. To ensure analytical precision, nested logistic regression analyses were employed. These were further refined by dividing respondents into 4 categories based on sexual orientation and disclosure (or "coming-out") status. Results: Among MSM, no definitive association was found between COVID-19 vaccination status and factors such as socioeconomic or sexual orientation-related attributes (with the latter including human immunodeficiency virus [HIV] status, sexual orientation, and disclosure experience). However, key determinants influencing COVID-19 infection were identified. Notably, people living with HIV (PLWH) exhibited a statistically significant predisposition towards COVID-19 infection. Furthermore, greater adherence to NPI practices among MSM corresponded to a lower likelihood of COVID-19 infection. Conclusions: This study underscores the high susceptibility to COVID-19 among PLWH within the LGBTQ+ community relative to their healthy MSM counterparts. Consequently, it is crucial to advocate for tailored preventive strategies, including robust NPIs, to protect these at-risk groups. Such measures are essential in reducing the disparities that may emerge in a post-COVID-19 environment.

• 한국전기전자재료학회논문지
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• 제19권10호
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• pp.912-917
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• 2006

In this paper, Trench emitter electrode IGBT structure is proposed and studied numerically using the device simulator, MEDICI. The breakdown voltage, on-state voltage drop, latch up current density and turn-off time of the proposed structure are compared with those of the conventional trench gate IGBT(TIGBT) structures. Enhancement of the breakdown voltage by 19 % is obtained in the proposed structure due to dispersion of electric field at the edge of the bottom trench gate by trench emitter electrode. In addition, the on-state voltage drop and the latch up current density are improved by 25 %, 16 % respectively. However increase of turn-off time in proposed structures are negligible.

• Macromolecular Research
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• 제17권9호
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• pp.714-717
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• 2009

Hole transport copolymers consisting of 3,4-ethylenedioxythiophene (EDOT) and N-4-butylphenyl-N,N-diphenylamine (BTPA) were synthesized by oxidative coupling reaction using $FeCl_3$ as an oxidant. These copolymers showed good solubility and their thin films showed sufficient morphological stability. The copolymers showed an absorption maximum around 320 nm. Copolymers had an oxidation peak at approximately $1.03{\sim}1.14V$ versus the Ag/AgCl electrode. The hole mobility increased with increasing portion of the EDOT unit. The hole mobility of the copolymer containing 57% of the EDOT unit showed the highest mobility of $3{\times}10^{-5}cm^2/V{\cdot}s$.

• Journal of Information Display
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• 제2권4호
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• pp.8-14
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• 2001

Three types of conjugated polymers, poly(PZ-Pi), poly(PZ-BPI) and poly(PZ-NPI) were synthesized by Schiff-base reaction. These new conjugated polymers exhibited improved solubility in common organic solvents due to the presence of alkyl side chains as well as azomethine groups, Double layer LEDs made with the synthesized polymers as emitting layer and $Alq_3$, as electron transporting layer exhibited enhanced EL emission and efficiency compared to those of single layer LEDs. Double layer LEDs exhibited gradual shift in the emission peak th the single layer LED, made of only $Alq_3$ as the emitting layer as the thickness of $Alq_3$ layer increased.

• 한국언어정보학회지:언어와정보
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• 제8권1호
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• pp.53-76
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• 2004

Negative polarity items(NPIs), which function as quantifiers are licensed in a syntactically strict way by negatives, which function as qualifiers, resulting in universal negating interpretations as pairs. We present a proposal to explain the related phenomena, in which the syntax and the semantics are closely related to each other, with Combinatory Categorial Grammar. For this purpose, we first adopt the usual approach to scrambling, but control its overgeneration with the use of markers, taking into account the complex syntactic phenomena involving NPIs and scrambling in Korean. We also propose to utilize polarity intensity as a novel feature, in order to account for the universal negating interpretations when NPIs are combined with negatives. Our proposal also explains the difference in readings when other quantifiers or qualifiers intervene the NPI and the related negatives.

• Clinical and Experimental Pediatrics
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• 제65권4호
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• pp.167-171
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• 2022

In the era of the coronavirus disease 2019 (COVID-19) pandemic, countries worldwide have implemented several nonpharmaceutical interventions (NPIs) to contain its spread before vaccines and treatments were developed. NPIs included social distancing, mask wearing, intensive contact tracing and isolation, and sanitization. In addition to their effectiveness at preventing the rapid spread of COVID-19, NPIs have caused secondary changes in the epidemiology of other infectious diseases. In Korea, various NPI stages have been implemented since the first confirmed case of COVID-19 on January 20, 2020. This review, based on a PubMed database search, shows the impact of NPIs on several infectious diseases other than severe acute respiratory syndrome coronavirus 2 in the COVID-19 pandemic era in Korea.