• Journal of Welding and Joining
• /
• v.19 no.6
• /
• pp.608-613
• /
• 2001

In this study, the rotary bending fatigue test was carried out with two kinds of base metal, martensite stainless steel STR3 and austenite stainless steel STR35 and the dissimilar friction welded material with them. To compare the fatigue fifes according to the notch positions, the small circular defect was worked on the bonded line, 1.0mm and 0.5mm distance form the bonded line. The fatigue limits of the STR3 and STR35 base metal were 429.0MPa and 409.4MPa respectably. In comparison with fatigue life at the same notch positions, the STR35 specimens showed about 190% for base metal, 82% for 1.0mm distance notched specimens higher than that of the STR3. But the fatigue life of the 0.5mm distance notched STR35 specimen showed about 35% lower than that of the STR3 specimen. And the bonded line notched specimen was much lower fatigue life than the other specimens because of separation of the bonded line.

• Journal of the Korean Institute of Telematics and Electronics
• /
• v.24 no.4
• /
• pp.719-726
• /
• 1987

In this paper, an adaptive IIR (infinite impulse response) notch filter of lattice type is constructed and its adaptation algorithm is proposed for the detection and retrieval of a sine wave signal embedded in noise. A modified method which adapts only one coefficient of the filter is also suggested. All these methods adapt the coefficients while keepting the poles of the filter inside the unit circle on z-plane, and thus they satisfy the condition on the stability of the IIR filter after it has converged. To investigate the convergence characteristics of these methods such as convergence speed and output S/N ratio, intensive computer simulation has been performed by varying the frequency of the sine wave and the input S/N ratio. And the results of the simulation have been compared to those of Rao and Kung's which shows relatively fast convergence speed. The methods proposed here, especially the second one. shows faster convergence speed and higher output S/N ratio than the Rao and Kung's.

• Proceedings of the KIEE Conference
• /
• 2008.10c
• /
• pp.44-46
• /
• 2008

This paper presented the notch effect of interior permanent magnet motor(IPM) with compound variable number of pole and slot. The selection of proper pole and slot which makes characteristic and efficiency of motor is very important on motor design. The motor which has 6pole and 9slot is at base. This paper is choose the 4pole 6slot motor which has 2:3 ratio then analyzed the characteristic.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.33 no.5
• /
• pp.463-468
• /
• 2009

Torsional oscillations of the drivetrain in electric vehicles are generated under rapid driving conditions. These lead to an uncomfortable jerking of the vehicle and an increased stress of the mechanical components. To suppress torsional oscillations, the low pass and notch filters between the torque command from the acceleration pedal and electric motor input torque are suggested. The filter parameters are optimized based on Taguchi method with $L_{18}(3^5)$ orthogonal array. The signal to noise (S/N) ratio mainly depends on slew rate of motor input torque, damping ratio and natural frequency of notch filter. With the proposed suppression control scheme, the S/N ratio is shown to be increased by 4.7dB and the torque overshoot of the drive shaft is reduced to 30%.

• Nuclear Engineering and Technology
• /
• v.30 no.4
• /
• pp.364-376
• /
• 1998

The statistical analysis method was applied to the evaluation of fracture toughness in the ductile-brittle transition temperature region. Because cleavage fracture in steel is of a statistical nature, fracture toughness data or values show a similar statistical trend. Using the three-parameter Weibull distribution, a fracture toughness vs. temperature curve (K-curve) was directly generated from a set of fracture toughness data at a selected temperature. Charpy V-notch impact energy was also used to obtain the K-curve by a $K_{IC}$ -CVN (Charpy V-notch energy) correlation. Furthermore, this method was applied to evaluate the neutron irradiation embrittlement of reactor pressure vessel (RPV) steel. Most of the fracture toughness data were within the 95% confidence limits. The prediction of a transition temperature shift by statistical analysis was compared with that from the experimental data.

• International journal of steel structures
• /
• v.18 no.4
• /
• pp.1384-1396
• /
• 2018

One of the failure modes observed in steel yield energy dissipating devices (SYEDs) excited by a strong earthquake would be the low-cycle fatigue failure. Fatigue cracks of a SYED are prone to initiate at the notch areas where stress concentration is usually occurred, which is demonstrated by the cyclic tests and analyses carried out for this study. Since the fatigue failure of SYEDs dramatically deteriorates their structural capacities, the thorough investigation on their fatigue life is usually required. To do this, sophisticated modeling with considering a time-consuming and complicate fracture mechanism is generally needed. This study makes an effort to investigate the low-cycle fatigue life of SYEDs predicted by a simplified method utilizing damage indices and fatigue prediction equations that are based on the plastic strain amplitudes obtained from typical finite element analyses. This study shows that the low-cycle fatigue failure of SYEDs predicted by the simplified method can be conservatively in good agreement with the test results of SYED specimens prepared for experimental validation.

• Journal of the Korea Concrete Institute
• /
• v.13 no.6
• /
• pp.568-574
• /
• 2001

From measured responses of concrete three-point bend tests, the average values of the responses have been calculated. The fracture behavior of continuously propagating concrete crack has been analyzed from the average responses. The experimental parameters of this study were the initial notch sizes of 25.4㎜ and 6.4 ㎜ and the processing times of 2,000 sec. and 20 sec . The different notch sizes were used for the effects of the size of fracture process zone and specimen geometry, and the processing times for those of initial creep. However the load-point displacement rate in this study did not affect the experimental responses seriously. The average loads were calculated from the average external work of a series of tests, and average crack lengths were determined by using strain gages. Before the peak load, the resistance curve could be determined from the size of fracture process zone, but unstable crack propagation of 88㎜ occurred at the load-point displacement of 0.088∼0.154㎜ after the peak load. The average fracture energy density G$\_$F/$\^$ave/ = 115 N/m occurred during the unstable crack propagation. The fracture process zones were fully developed at the crack length of 111㎜, and the sizes of fracture process zone for initial notches of 25.4㎜ and 6.4㎜ were 86㎜ and 105㎜, respectively. Average fracture energy densities of the resistance curves after full development of fracture process zone were 229 N/m for the initial notch of 25.4㎜ and 284 N/m for 6.4㎜. The values were more than twice of G$\_$F/$\^$ave/.

• Journal of Life Science
• /
• v.32 no.3
• /
• pp.210-221
• /
• 2022

This study investigated the mechanisms underlying the anti-cancer effects of non-steroidal anti-inflammatory drugs (NSAIDs) in human cancer cells in combination with either N-[N-(3, 5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester (DAPT), a γ-secretase inhibitor, or MHY2245, a new synthetic sirtuin 1 inhibitor. The results showed both DAPT and MHY2245 as novel chemosensitizers of human colon cancer KM12 and human hepatocellular carcinoma SNU475 cells to NSAIDs involving celecoxib and 2, 5-dimethyl celecoxib. The NSAID-induced cytotoxicity of these cells was significantly increased by DAPT and MHY2245 in a cyclooxygenase-2 independent manner. In addition, DAPT and MHY2245 reduced levels of p62, Notch1 intracellular domain, and multiple cancer stemness (CS)-related markers including Notch1, CD44, CD133, octamer-binding transcription factor 4, mutated p53 and c-Myc. However, the level of activating transcription factor 4 (ATF4) was enhanced, probably indicating the down-regulation of multiple CS-related markers by DAPT or MHY2245-mediated autophagy induction. Moreover, the NSAID-mediated reduction of p62/nuclear factor erythroid-derived 2-like 2 and CS-related marker proteins and the up-regulation of C/EBP homologous protein (CHOP)/ATF4 were accelerated by DAPT and MHY2245. As such, the combination of NSAID and either DAPT or MHY2245 resulted in higher cytotoxicity than NSAID alone by accelerating the down-regulation of multiple CS-related markers and PARP activation, indicating that both inhibitors promote NSAID-mediated autophagic cell death, possibly through the CHOP/ATF4 pathway. In conclusion, either combination strategy may be useful for the effective treatment of human cancer cells expressing CS-related markers.

• Journal of Power Electronics
• /
• v.12 no.4
• /
• pp.654-663
• /
• 2012

In this paper, a digital control strategy based on equivalent fundamental and odd harmonic resonators is proposed for single-phase DVRs. By using a delay block, which can be equivalent to a bank of resonators, it rejects the fundamental and odd harmonic disturbances effectively. The structure of the single closed-loop control system consists of a delay block, a proportional gain and a set of zero phase notch filters. The principle of the controller design is discussed in detail to ensure the stability of the system. Both the supply voltage and the load current feedforwards are used to improve the response speed and the ability to eliminate disturbances. The proposed controller is simple in terms of its structure and implementation. It has good performances in harmonic compensation and dynamic response. Experimental results from a 2kW DVR prototype confirm the validity of the design procedure and the effectiveness of the control strategy.

• Toxicological Research
• /
• v.26 no.4
• /
• pp.245-252
• /
• 2010

Epithelial-mesenchymal transition (EMT) is a complex process in which epithelial cells acquire the characteristics of invasive mesenchymal cells. EMT has been implicated in cancer progression and metastasis as well as the formation of many tissues and organs during development. Epithelial cells undergoing EMT lose cell-cell adhesion structures and polarity, and rearrange their cytoskeletons. Several oncogenic pathways such as transforming growth factor (TGF)-$\beta$, Wnt, and Notch signaling pathways, have been shown to induce EMT. These pathways have activated transcription factors including Snail, Slug, and the ZEB family which work as transcriptional repressors of E-cadherin, thereby making epithelial cells motile and resistant to apoptosis. Mounting evidence shows that EMT is associated with cell invasion and tumor progression. In this review, we summarize the characteristic features of EMT, pathways leading to EMT, and the role of EMT in cell invasion. Three topics are addressed in this review: (1) Definition of EMT, (2) Signaling pathways leading to EMT, (3) Role of EMT in cell invasion. Understanding the role of EMT in cell invasion will provide valuable information for establishing strategies to develop anti-metastatic therapeutics which modulate malignant cellular processes mediated by EMT.