• Title/Summary/Keyword: NOP

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The Classification and Diagnosis of Neuropathic orofacial pain (구강안면 신경병성 통증의 진단 및 분류)

  • Ahn, Jong-Mo
    • The Journal of the Korean dental association
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    • v.49 no.6
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    • pp.316-320
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    • 2011
  • Neuropathic orofacial pain (NOP) is initiated or caused by a priomary lesion or dysfunction in the peripheral nervous system or the central nervous system. NOP is divided into paroxysmal and continuous by duration of pain. NOP is important for dentists, because they can occur after dental procedures, such as extractions, endodontic treatment, and dental implant insertion. Dentists should have concern about NOP, because it is difficult to diagnose and treat.

Role of nociceptin/orphanin FQ and nociceptin opioid peptide receptor in depression and antidepressant effects of nociceptin opioid peptide receptor antagonists

  • Park, Jong Yung;Chae, Suji;Kim, Chang Seop;Kim, Yoon Jae;Yi, Hyun Joo;Han, Eunjoo;Joo, Youngshin;Hong, Surim;Yun, Jae Won;Kim, Hyojung;Shin, Kyung Ho
    • The Korean Journal of Physiology and Pharmacology
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    • v.23 no.6
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    • pp.427-448
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    • 2019
  • Nociceptin/orphanin FQ (N/OFQ) and its receptor, nociceptin opioid peptide (NOP) receptor, are localized in brain areas implicated in depression including the amygdala, bed nucleus of the stria terminalis, habenula, and monoaminergic nuclei in the brain stem. N/OFQ inhibits neuronal excitability of monoaminergic neurons and monoamine release from their terminals by activation of G protein-coupled inwardly rectifying $K^+$ channels and inhibition of voltage sensitive calcium channels, respectively. Therefore, NOP receptor antagonists have been proposed as a potential antidepressant. Indeed, mounting evidence shows that NOP receptor antagonists have antidepressant-like effects in various preclinical animal models of depression, and recent clinical studies again confirmed the idea that blockade of NOP receptor signaling could provide a novel strategy for the treatment of depression. In this review, we describe the pharmacological effects of N/OFQ in relation to depression and explore the possible mechanism of NOP receptor antagonists as potential antidepressants.

Interference Check for Reactor In-Core Instrumentation Guide Tube Routing (원자로 노내계측기 안내관의 배열을 위한 간섭검증)

  • Cho, Duk-Sang
    • Journal of the Korean Society of Industry Convergence
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    • v.3 no.3
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    • pp.201-207
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    • 2000
  • In this study, methodologies for checking the interference between in-core instrumentation (ICI) guide tubes for routing of ICI guide tubes in the reactor coolant system of typical Pressurized Water Reactor under cold and normal operation (NOP) conditions are presented. The closest points of ICI guide tubes under cold condition are calculated by using minimize technique and are used as data for NOP analysis. Movements of ICI guide tubes under NOP condition are performed by the commercial computer code, SUPERPIPE.

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A VLIW Code Generation Technique Utilizing NOP Instruction Slot (NOP 명령어 슬롯을 활용하는 VLIW 코드 생성기법)

  • 문현주;이승수;김석주;김석일
    • Proceedings of the Korean Information Science Society Conference
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    • 2000.10c
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    • pp.615-617
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    • 2000
  • 본 논문에서는 VLIW 목적코드에 존재하는 NOP 명령어 슬롯에 의미있는 명령어를 중복 삽입하도록 함으로써 원래의 방법에서 존재하였던 자료의존관계를 해소하여 실행시간의 지연을 방지하는 기법을 연구하였다. 이 경우에 하나의 긴 명령어에 동일한 명령어가 둘 이상 포함될 수 있으므로 연산 관계에 이은 쓰기 단계에서 여러개의 명령어가 동일한 레지스터 파일의 주소에 쓰기를 함에 따른 충돌을 피할 수 없다. 본 논문에서는 연산처리 별로 쓰기 단계에서 연산 결과를 레지스터 파일에 쓰도록 허용할 것인지에 대한 정보를 명령어에 포함하는 TiPS 구조와 TiPS 구조에 적합한 목적코드 생성 알고리즘을 제안하였다. 목적코드 생성 알고리즘은 연산처리기별로 연속적으로 실행되는 명령어간의 자료의존관계를 해소하기 위하여 NOP 대신에 다른 연산처리기에서 실행할 명령어를 수행하도록 동일한 명령어를 복사하여 할당할 수 있다. 실험 결과, 명령어 복사 기법은 기존의 기법에 비하여 전체 실행 사이클을 크게 단축시킬 수 있음을 보여주었다.

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The effects of dietary supplementation with 3-nitrooxypropanol on enteric methane emissions, rumen fermentation, and production performance in ruminants: a meta-analysis

  • Kim, Hanbeen;Lee, Hyo Gun;Baek, Youl-Chang;Lee, Seyoung;Seo, Jakyeom
    • Journal of Animal Science and Technology
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    • v.62 no.1
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    • pp.31-42
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    • 2020
  • The aim of this study was to investigate the effects of 3-nitrooxypropanol (NOP) on gas production, rumen fermentation, and animal performances depending on animal type using a meta-analysis approach. A database consisted of data from 14 studies, 18 experiments and 55 treatments. The supplementation of NOP linearly decreased methane (CH4) emissions [g/kg dry matter intake (DMI)] regardless of animal type and length of experimental period (beef, p < 0.0001, R2 = 0.797; dairy, p = 0.0003, R2 = 0.916; and long term, p < 0.0001, R2 = 0.910). The total volatile fatty acids (VFA) concentration and the proportion of acetate, based on beef cattle database, were significantly decreased with increasing NOP supplementation (p = 0.0015, R2 = 0.804 and p = 0.0003, R2 = 0.918), whereas other individual VFAs was increased. Based on the dairy database, increasing levels of NOP supplementation linearly decreased proportion of acetate (p = 0.0284, R2 = 0.769) and increased that of valerate (p = 0.0340, R2 = 0.522), regardless of significant change on other individual VFAs. In animal performances, the DMI, from beef cattle database, tended to decrease when the levels of NOP supplementation increased (p = 0.0574, R2 = 0.170), whereas there was no significant change on DMI from dairy cattle database. The NOP supplementation tended to decrease milk yield (p = 0.0606, R2 = 0.381) and increase milk fat and milk protein (p = 0.0861, R2 = 0.321, p = 0.0838, R2 = 0.322). NOP is a viable candidate as a feed additive because of its CH4 mitigation effects, regardless of animal type and experiment period, without adverse effects on animal performances.

Performance Improvement of SVLIW Architectures by Removing LNOPs from An Object Code (목적 코드에서 LNOP 코드가 제거됨에 따른 SVLIW 구조의 성능 향상)

  • Jeong, Bo-Yun;Jeon, Joong-Nam;Kim, Suk-Il
    • The Transactions of the Korea Information Processing Society
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    • v.4 no.9
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    • pp.2269-2279
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    • 1997
  • SVLIW (Superscalar VLIW) processor, a family of VLIW processors schedules very long instruction words at runtime. If a very long instruction word that is to be issued occurs data dependence relations and/or resource conflicts with those words that were under execution, a long NOP word is issued instead of the word until all the data dependence relations and/or resource conflicts have been resolved. Thus, LNOPs can be removed in object codes for SVLIW processors. In this paper, we measure an improvement of the cache hit ratio caused by removing LNOPs in the object code. We also analyze an improvement of the processor performance due to higher cache hit ratio of the processor. Benchmark tests promise that the performance of SVLIW processors is improved more than 5% compared with that of traditional VLIW processors.

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Implementation of MNIST classification CNN with zero-skipping (Zero-skipping을 적용한 MNIST 분류 CNN 구현)

  • Han, Seong-hyeon;Jung, Jun-mo
    • Journal of IKEEE
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    • v.22 no.4
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    • pp.1238-1241
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    • 2018
  • In this paper, MNIST classification CNN with zero skipping is implemented. Activation of CNN results in 30% to 40% zero. Since 0 does not affect the MAC operation, skipping 0 through a branch can improve performance. However, at the convolution layer, skipping over a branch causes a performance degradation. Accordingly, in the convolution layer, an operation is skipped by giving a NOP that does not affect the operation. Fully connected layer is skipped through the branch. We have seen performance improvements of about 1.5 times that of existing CNN.

Field Police Activity Focused on Community Policig (지역사회 경찰활동 관점에서 본 현장 경찰활동)

  • Kim, Hyun-Dong;Lee, Moon-Soo;Jo, Hyun-Bin
    • The Journal of the Korea Contents Association
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    • v.13 no.6
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    • pp.177-186
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    • 2013
  • Recently, with the sudden changes in the security environment, expectations towards the police and fear towards safety are increasing. Thus, the local community police operation, which creates a mutually cooperative relationship between the police and local residents, is coming to the fore as the paradigm of the nationwide police operation. The police operation in Korea has also gone through change, and as part of the local community police operation, Korea has implemented a community police system since 2003. Recently, the system has been going through change in that the operations are centralizing around not only prevention of crime including the safe city program, protection of multicultural families, response to foreign crime, protection of the socially disadvantaged but also life security of the citizens. Along these lines, this study seeks to examine conditions of the three elements of local community police operation - Strategic Oriented Policing (SOP), Neighborhood Oriented Policing (NOP), Problem Oriented Policing (POP) - and policy suggestions accordingly.

Factors Influencing on Bank Capital and Profitability: Evidence of Government Banks in Indonesia

  • ANGGRAENI, Anggraeni;BASUKI, Basuki;SETIAWAN, Rahmat
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.2
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    • pp.185-191
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    • 2022
  • The purpose of this research is to see if liquidity, non-performing assets, sensitivity, and efficiency have an impact on the profitability and capital of Indonesian state-owned banks. A random sample of public banks was used in this study. The data was collected from the first quarter of 2014 to the fourth quarter of 2019. Purposive sampling was used as the sampling technique. According to the findings of this study, liquidity (LDR) had a significant positive effect on capital but had no significant effect on profitability. Productive asset quality as proxied by the ACA and NPL ratios did not affect profitability or capital. As for the sensitivity ratio, which was proxied by the ratio of NOP and IRR, there were differences in behavior. Sensitivity had no significant impact on profitability or capital, while NOP had a significant positive impact on capital but not on profitability. In terms of efficiency, both OER and FBIR had a significant effect on profitability and capital, although in different directions. OER has a significant negative impact on both profitability and capital. Fee-based income (FBIR) had a significant positive impact on capital, but it had the opposite effect on profitability.

VLIW architecture for compensating simple bypassing paths (간단한 바이패싱 회로를 보상하는 VLIW 구조)

  • 김석주
    • Proceedings of the Korea Multimedia Society Conference
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    • 2002.05c
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    • pp.27-32
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    • 2002
  • 본 논문에서는 NOP 이 차지하는 슬롯에 의미 있는 명령어를 중복 할당하여 자료의존 관계를 해소하고 프로그램 실행 사이클을 단축시키는 명령어 중복 스케줄링 기법을 적용할 수 있는 VLIW 구조인 TiPs(Tiny Processors) 구조를 제안하였으며 TiPs는 회로의 복잡도를 증가시키지 않으면서 실행시간을 단축시켜 가상의 바이패싱 회로를 추가한 효과를 얻을 수 있다. 실험 결과 TiPs에서 명령어 중복 스케줄링 기법을 적용할 경우 8% ~ 25%의 성능 향상 효과가 있음을 알 수 있었다.

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