• Proceedings of the Korean Nutrition Society Conference
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• 2002.06a
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• pp.613-616
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• 2002

락토페린은 주로 유즙에 많이 포함되어 있으며 인간분비물 등에서도 발견되는 당단백질로써, 미생물 감염에 대한 방어작용이 있는 것으로 알려져 있다. 락토페린의 미생물에 대한 방어작용은 미생물 성장에 필요한 철이온이 락토페린에 결합하여 성장을 저해하기 때문인 것으로 알려져 있다. 락토페린은 이외에도 염증반응의 조절, 임파세포의 성장촉진 등 면역반응에도 관여하는데 이러한 활성은 철에 결합하는 성질과는 무관하게 일어나며 락토페린이 DNA에 결합하는 성질과 관련이 있는 것으로 추측되어진다. 락토페린은 DNA에 결합하여 유전자의 전사에 관여할 것으로 여겨지는데 그 동안 어떤 유전자의 발현에 관여하는지에 대해서 알려진 바가 없었다. 최근 본 연구팀은 락토페린이 포유세포의 세포유전자의 전사에 관여하는지를 분석한 결과 락토페린 결합부위를 가지고 있는 유전자중의 하나인 인간 인터루킨-1$eta$ 유전자의 전사를 활성화시킨다는 연구 결과를 보여 주었다. 인간 myelogenous leukaemia 세포주인 K562 세포를 락토페린과 phorbol myristate acetate(PMA)로 함께 처리하면 K562 세포의 인터루킨-1$\beta$ mRNA의 양은 PMA 단독으로 처리하였을 때 보다 상승적으로 더 많이 유도됨을 보여주었다. 또한 IL-1$\beta$/Luciferase 융합 유전자를 K562 배양세포에 넣어 전사 활성을 비교함으로써 락토페린에 의한 인터루킨-1$\beta$의 전사활성을 확인하였다. 락토페린을 전체, N-말단, 혹은 C- 말단 부위를 COS-1 세포에 발현시켜 전사 활성을 측정한 결과 C-말단 쪽은 전사활성이 없었으나 N-말단 90개 아미노산 부위(NIa라 명명)가 전사활성을 가지고 있음을 규명하였다. 본 연구결과는 락토페린이 인터루킨-I$\beta$의 유전자의 전사에 역할을 하고 있음을 보여 주고 있으며 또한 인터루킨-1$\beta$의 유전자 외에도 락토페린 결합 부위를 유전자의 조절부위에 포함하고 있는 세포 유전자의 전사도 관여할 수 있음을 제시하고 있다.

• International Union of Geodesy and Geophysics Korean Journal of Geophysical Research
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• v.26 no.1
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• pp.31-41
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• 1998

The climatic characteristics of summer in 1998 are analyzed with the weather observational data and the upper air observational data. The temperature of that period is lower than that of normal years and the precipitation is larger. Due to the heavy rainfall which started at July 31, rain pured down compared to normal years and the maximum precipitation recorded at the many observational stations, particularly in Seoul, Kyunggi-Do region and mountanious districts like Taegwallyong, Mt. Sokri and Mt. Chiri. The patterns of general circulations in 1982/98 and 1997/98 are compared each other and are analyzed. The anomaly patterns of stream functions on winter in two El Nio years are simialr. The counterclockwise circulation occurred near the date line and the clockwise circulation was appeared near the Hwanam region and Alaska. These patterns are opposite to those of La Nia year, 1988/89. And the anomaly patterns of 500hPa geopotential height in summer are similar, too. The low temperature and much rain were dominated in summer of 1997/98. These phenomena is similar to the existing results of research, that temperature is low and precipitation is large in summer of El Nio years.

• Asian-Australasian Journal of Animal Sciences
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• v.26 no.3
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• pp.349-357
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• 2013

The aim of this study was to evaluate the efficiency of supplements containing different energy sources in relation to mineral supplementation of steers grazing guineagrass (Panicum maximum cv Tanz$\hat{a}$nia) pasture, during the dry season. The experimental design was a randomized block with three treatments and four replications. The treatments consisted of a mineral supplementation and two other supplements, one based on corn seed and the other based on soybean hulls, and provided at 0.8% of body weight. Forty-eight, 12 month-old crossbred steers with an average initial body weight of 267 kg, were assigned to twelve paddocks (1,125 ha) of guineagrass. The animals that were fed with soybean hulls and corn seed presented a greater average daily gain (0.982 and 0.937) when compared with the mineral supplementation. Soybean hulls can be used as a satisfactory food source, replacing corn as an energy source in the supplementation of beef cattle without compromising animal performance.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.4
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• pp.1535-1554
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• 2016

This paper proposes a novel channel assignment scheme called multi-cluster based dynamic channel assignment (MC-DCA) to improve system performance for the downlink of dense femtocell networks (DFNs) based on orthogonal frequency division multiple access (OFDMA) and frequency division duplexing (FDD). In order to dynamically assign channels for femtocell access points (FAPs), the MC-DCA scheme uses a heuristic method that consists of two steps: one is a multiple cluster assignment step to group FAPs using graph coloring algorithm with some extensions, while the other is a dynamic subchannel assignment step to allocate subchannels for maximizing the system capacity. Through simulations, we first find optimum parameters of the multiple FAP clustering to maximize the system capacity and then evaluate system performance in terms of the mean FAP capacity, unsatisfied femtocell user equipment (FUE) probability, and mean FAP power consumption for data transmission based on a given FUE traffic load. As a result, the MC-DCA scheme outperforms other schemes in two different DFN environments for commercial and office buildings.

• The Journal of Korean Association of Computer Education
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• v.15 no.2
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• pp.47-55
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• 2012

We discovered the fact that the most important factor for judging adults' internet addiction in the K-scale method which was developed by Korea National Information Society Agency (NIA), has composed of 4 categories including 20 items, is tolerance and preoccupation factor from the experiments by using data mining techniques. In this research, we propose a new internet addiction diagnostic method based on the degree of tolerance considering users' non-duty internet activities. From some questionnaire participants, their feedbacks for the K-scale and the proposed diagnostic method were collected, and then we confirmed that the proposed user-centered diagnostic method is effective to find undiscovered addicts due to individuals's intention in the K-scale.

• Journal of the Korean Institute of Intelligent Systems
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• v.21 no.3
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• pp.317-322
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• 2011

Korean adults' internet addiction diagnosis measure, K-scale developed by Korea National Information Society Agency (NIA), has composed of 4 categories including 20 items. This scale can diagnose user's internet addiction with individual's questionnaire items. Most of previous research works were tried to know reasons of internet addiction and to judge whether adolescents are addicted or not with their samples. In this research, it is the goal to find the key component to judge individual's internet addiction by using a decision tree in the data mining field and a principal component analysis in statistics. From the experimental results, we would discover that tolerance and preoccupation factor is the most important one to affect adult's internet addiction.

• Journal of Contemporary Eastern Asia
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• v.18 no.1
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• pp.124-152
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• 2019

Smart city, which employs information and communication technology (ICT) to resolve urban problems, is gaining more research attention in the innovation research. However, most previous studies regard citizens as merely passive accepters of the smart city services, focusing on individual private values. The present study aims to expand existing limited perspectives by applying public value management theory. Drawing from the literature review, we developed a dual perspective that a smart city service should encompass: private and public value. Then we set up a causal relationship between the value recognitions and intention to adopt smart city services. We further related antecedent variables to the dual value recognition in terms of citizens' characteristics: prior knowledge, personal innovativeness, and citizenship. Two case subjects among currently operating smart city services in South Korea were selected to empirically investigate our hypothesis. Results confirm the recognition of both public and private value is significantly related to the citizens' personal characteristics and resultant attitude towards acceptance and support for diffusion of the smart city services. This study is expected to provide useful implications for a new angle for the recipient of the smart city services, value orientation of the services, citizen's participation, and method selection for promotion.

• Journal of Information Technology Services
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• v.20 no.1
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• pp.117-130
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• 2021

The Korean society is transforming into the intelligence information society rapidly during the 4th industrial revolution. But middle aged and elderly people are hard to access and accept these changes. So, the purpose of this study is to examine the Intelligence information society factors affects life satisfaction among the elderly by moderating effect of on/offline social capital. This study analyzed data of 2,303 people between the ages over 50 from the 2018 Digital Divide Survey conducted by the National Information Society Agency (NIA) using SPSS26.0. The result showed that sex, age, education, household type, Intelligence information society perception, expectation, anxiety are significantly effected life satisfaction. Also on/offline social capital had moderating effect between intelligence information society and life satisfaction. Based on the results of this study proviedes a basis for developing a success model for elderly people who accepts the intelligence information society. Also, this study identifies the implications and future studies are suggested.

• Journal of Korean Society of Water and Wastewater
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• v.38 no.2
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• pp.95-107
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• 2024

This study proposes the use of a cobalt-based Prussian blue analogue (Co-PBA; potassium cobalt hexacyanoferrate), as an adsorbent for the cost-effective recovery of aqueous ammonium ions. The characterization of Co-PBA involved various techniques, including Fourier-transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, nitrogen adsorption-desorption analysis, and zeta potential. The prepared Co-PBA reached an adsorption equilibrium for ammonium ions within approximately 480 min, which involved both surface adsorption and subsequent diffusion into the interior. The isotherm experiment revealed a maximum adsorption capacity of 37.29 mg/g, with the Langmuir model indicating a predominance of chemical monolayer adsorption. Furthermore, the material consistently demonstrated adsorption efficiency across a range of pH conditions. Notably, adsorption was observed even when competing cations were present. Co-PBA emerges as a readily synthesized adsorbent, underscoring its efficacy in ammonium removal and selectivity toward ammonium.

• Journal of Digital Convergence
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• v.18 no.6
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• pp.271-277
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• 2020

Machine translation refers to software that translates a source language into a target language, and has been actively researching Neural Machine Translation through rule-based and statistical-based machine translation. One of the important factors in the Neural Machine Translation is to extract high quality parallel corpus, which has not been easy to find high quality parallel corpus of Korean language pairs. Recently, the AI HUB of the National Information Society Agency(NIA) unveiled a high-quality 1.6 million sentences Korean-English parallel corpus. This paper attempts to verify the quality of each data through performance comparison with the data published by AI Hub and OpenSubtitles, the most popular Korean-English parallel corpus. As test data, objectivity was secured by using test set published by IWSLT, official test set for Korean-English machine translation. Experimental results show better performance than the existing papers tested with the same test set, and this shows the importance of high quality data.