• Parasites, Hosts and Diseases
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• 제42권1호
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• pp.35-40
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• 2004

The nfa 1 gene was cloned from a cDNA library of pathogenic Naegleria fowleri by immunoscreening; it consisted of 360 bp and produced a 13.1 kDa recombinant protein (rNfa1) that showed the pseudopodia-specific localization by immunocytochemistry in the previous study. Based on the idea that the pseudopodia-specific Nfa1 protein mentioned above seems to be involved in the pathogenicity of N. fowleri, we observed the effect of an anti-Nfa1 antibody on the proliferation of N. fowleri trophozoites and the cytotoxicity of N. fowleri trophozoites on the target cells. The proliferation of N. fowleri trophozoites was inhibited after being treated with an anti-Nfa1 polycional antibody in a dose-dependent manner for 48 hrs. By a light microscope, CHO cells co-cultured with N. fowleri trophozoites (group I) for 48 hrs showed severe morphological destruction. On the contrary, CHO cells co-cultured with N. fowleri trophozoites and anti-Nfa1 polyclonal antibody (1:100 dilution) (group II) showed less destruction. In the LDH release assay results, group I showed 50.6% cytotoxicity, and group II showed 39.3%. Consequently, addition of an anti-Nfa1 polyclonal antibody produced a decreasing effect of in vitro cytotoxicity of N. fowleri in a dose-dependent manner.

• Journal of Electrical Engineering and Technology
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• 제13권2호
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• pp.989-997
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• 2018

Massive event stream brings us great challenges in its volume, velocity, variety, value and veracity. Picking up some valuable information from it often faces with long detection time, high memory consumption and low detection efficiency. Aiming to solve the problems above, an efficient complex event detection method based on NFA_HTS (Nondeterministic Finite Automaton_Hash Table Structure) is proposed in this paper. The achievement of this paper lies that we successfully use NFA_HTS to realize the detection of complex event from massive RFID event stream. Specially, in our scheme, after using NFA to capture the related RFID primitive events, we use HTS to store and process the large matched results, as a result, our scheme can effectively solve the problems above existed in current methods by reducing lots of search, storage and computation operations on the basis of taking advantage of the quick classification and storage technologies of hash table structure. The simulation results show that our proposed NFA_HTS scheme in this paper outperforms some general processing methods in reducing detection time, lowering memory consumption and improving event throughput.

• 대한비뇨기종양학회지
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• 제15권3호
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• pp.137-142
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• 2017

Purpose: To examine and compare the perioperative outcomes of laparoscopic adrenalectomy (LA) and to determine its efficacy in patients with nonfunctioning adrenal adenomas (NFA) and subclinical Cushing syndrome (SCS). Materials and Methods: We retrospectively analyzed the clinical data obtained from 79 consecutive patients who underwent LA for the treatment of either NFA (n=35) or SCS (n=44) between 2011 and 2016. All patients had undergone computed tomography, as well as endocrinological tests to confirm the diagnosis prior to the adrenalectomy. The primary endpoint was improved metabolic parameters relating to diabetes, hypertension, dyslipidemia, and obesity. Results: Patients with SCS compared to those with NFA showed a higher occurrence of diabetes (29.5% vs. 11.4%), hypertension (59.1% vs. 34.3%), and dyslipidemia (43.2% vs. 14.3%). Patients with SCS showed a smaller median tumor size compared to those with NFA (2.5 cm vs. 5 cm). No significant perioperative complications ${\geq}$ Clavien-Dindo classification grade III were observed in any patient (SCS or NFA group). In terms of their metabolic profile, patients with SCS showed a significant postoperative improvement in hypertension (50.0%), diabetes (53.9%), dyslipidemia (31.6%), and obesity (29.2%). However, patients with NFA showed a postoperative improvement only in dyslipidemia (40.0%) and obesity (4.8%). Conclusions: Owing to absence of significant perioperative complications and the marked postoperative improvement in metabolic impairment, LA is a useful treatment strategy in patients diagnosed with SCS. In contrast, LA was not observed to show beneficial effects in correcting/improving the metabolic profile in patients presenting with NFA.

• 감성과학
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• 제22권3호
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• pp.77-90
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• 2019

본 연구는 기본 욕구의 개인차에 따라 메시지에 담긴 행동을 추구하는 데 효과적인 메시지 제공자가 다른지 알아보고자 하였다. Haddock, Maio, Arnold, & Huskinson (2008)에 의하면, 감성 욕구(NFA)가 높은 사람은 정서 기반의 메시지에, 인지 욕구(NFC)가 높은 사람은 인지 기반의 메시지에 더 영향을 받았다. 본 연구는 이러한 기본 욕구의 개인차가 메시지뿐 아니라 메시지 제공자에까지 적용할 수 있으리라 생각했다. 예를 들면, 감성 욕구가 높은 사람은 전문가보다 의미 있는 타인에게 전달받은 메시지를 더 잘 수용할 수 있다. 이에 따라, 본 연구는 VR에서 개인별 건강 조언에 효과적인 메시지 제공자를 파악하고자, 개인의 욕구 (2: NFA, NFC), 메시지 제공자 (3: 전문가, 의미 있는 타인, 타인) 그리고 VR 착용 (2: Text, VR)에 따른 선호도와 일상생활 스트레스 관리에 대한 자기 효능감을 측정하였다. 실험결과, 예상과 달리, 기본 욕구와 메시지 제공자의 특성에 따른 일치 효과는 발견할 수 없었다. 그러나, 감성 욕구가 높은 집단이 VR 건강 조언에 더 적합하다는 경향을 파악할 수 있었다. 본 연구의 의의는 VR 환경에서 개인의 맞춤형 메시지 제공자를 파악하고자 한 데 있다. 또한, 본 연구는 초기 단계의 연구로 추후 VR 환경의 건강 조언 연구에 기여하리라 예상한다.

• 한국게임학회 논문지
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• 제2권2호
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• pp.52-59
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• 2002

이 논문에서는 FSM과 확률적 FSM, NFA 등이 게임에서 NPC의 행동 지정에 쓰인 방식을 소개하고, 기존 방법에서 확률적 FSM이나 NFA의 단점을 보완할 수 있는 새로운 확률적 FSM 방식을 제안한다. 즉, 확률 유한오토마타의 추론 방식을 이용하여 다양한 NPC나 컴퓨터 플레이어의 인성이나 특성을 자동적으로 게임에 반영하기 위한 방법을 제안한다. 이 방법으로 수 많은 게이머들의 인성이나 특성을 자동적으로 파악하여, 실제 게임에서 사용되는 NPC나 컴퓨터 플레이어에게 부여해 줄 수 있고, 또한 NPC들의 인성을 다양하게 부여함으로써 게임의 재미를 더 향상시킬 수가 있다.

• 한국식품영양학회지
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• 제28권5호
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• pp.752-758
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• 2015

This study was conducted to investigate the antioxidant and anti-obesity activity of ethanol extracts from fermented Arctium lappa L. Arctium lappa fermented twice with Phellinus linteus ($2^{nd}$ FA) showed more DPPH radical scavenging activity than non-fermented Arctium lappa (NFA), and Arctium lappa fermented once ($1^{st}$ FA) at a concentration of 62.5 ppm. The $2^{nd}$ FA showed the highest level of ABTS radical scavenging activity at concentration range of 31.5~125 ppm. The ABTS free radical scavenging activities of $1^{st}$ FA and $2^{nd}$ FA were similar to that of BHA, a synthetic antioxidant, at a concentration of 250 ppm. The total polyphenol content of $2^{nd}$ FA was higher than those of NFA and $1^{st}$ FA. The flavonoid content was significantly increased in $1^{st}$ FA and $2^{nd}$ FA than NFA. During adipocyte differentiation, lipid accumulation in 3T3-L1 cells was significantly decreased in the order of NFA, $1^{st}$ FA, and $2^{nd}$ FA at all concentrations. In conclusion, the antioxidant and anti-obesity activities of A. lappa were increased depending on the degree of fermentation. It is suggested that fermented Arctium lappa, especially $2^{nd}$ FA, could be used as a natural ingredient for functional foods and medicine.

• Physical Therapy Rehabilitation Science
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• 제13권2호
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• pp.152-162
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• 2024

Objective: This study was conducted to analyze the effect of wearable Electromyography-controlled functional electrical stimulation (EMG-controlled FES) System on Gait Function and cardiopulmonary metabolic efficiency during walking in older adults. Design: Cross-section study Methods: Total 22 older adult participants suitable to selection criteria of this study participated in this study. The EMG-controlled FES System, which functions as a wearable physical activity assist FES system was used. All participations performed randomly assigned two conditions (Non-FES assist [NFA], FES assist [FA]) of walking. In all conditions, spatio-temporal parameters and kinematics and kinetics parameters during walking was collected via 3D motion capture system and 6 minutes walking test (6MWT) and metabolic cost during walking and stairs climbing was collected via a portable metabolic device (COSMED K5, COSMED Srl, Roma, Italy). Results: In Spatio-temporal parameters aspects, The EMG-controlled FES system significantly improved gait functions measurements of older adults with sarcopenia at walking in comparison to the NFA condition (P<0.05). Hip, knee and ankle joint range of motion increased at walking in FA condition compared to the NFA condition (P<0.05). In the FA condition, moment and ground reaction force was changed like normal gait during walking of older adults in comparison to the NFA condition (P<0.05). The EMG-controlled FES system significantly reduced net cardiopulmonary metabolic energy cost, net energy expenditure measurement at stairs climbing (P<0.05). Conclusions: This study demonstrated that EMG-controlled FES is a potentially useful gait-assist system for improving gait function by making joint range of motion and moment properly.

• Corrosion Science and Technology
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• 제12권2호
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• pp.79-84
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• 2013

In general, pipelines at nuclear power plants are affected by various types of degradation mechanisms and may be ruptured after gradually thinning. FAC (Flow-Accelerated Corrosion) is typical aging mechanism affecting the secondary side piping system. In Korea nuclear power plants, CHECWORKS program have been used for management of wall thinning damages. However, sometimes, CHECWORKS program shows wrong results at the stage of NFA (Network Flow Analysis) in case of complex pipelines. This paper describes the calculation results of pressure drop in a complex pipeline and single line by using the CHECWORKS program and the analysis results are compared with those of engineering calculation results including errors between them.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2006년도 한국컴퓨터종합학술대회 논문집 Vol.33 No.1 (C)
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• pp.25-27
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• 2006

XPath 명세는 XML 원소 내용을 필터링하기 위한 질의어 작성이 어렵다. 본 논문은 이러한 문제점을 해결하기 위해 SQL의 LIKE 연산자에서 사용되던 특별한 매칭 문자 '%' 를 허용한 확장된 XPath 명세와 그것을 표준 질의어로 사용하는 문서-중심적 XML 필터링 기법인 Pfilter를 제안한다. Pfilter는 값-기반 술어(value-based predicate)에서 피연산자의 공통 앞부분 문자를 공유하여 값-기반 술어의 처리 성능을 향상시킨다. 또한 본 논문은 Pfilter와 대표적인 데이터-중심적 XML 필터링 기법인 Yfilter를 값-기반 술어 처리의 확장성과 효율성에 대해 비교하고 Pfilter의 값-기반 술어 삽입, 삭제, 처리 결과를 제공한다.

• 복식문화연구
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• 제30권4호
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• pp.579-593
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• 2022

This study examines the surface characteristics, electrical conductivity, electromagnetic wave blocking characteristics, infrared (IR) transmittance, stealth function, thermal characteristics, and moisture characteristics of IR thermal imaging cameras. Nylon film (NFi), nylon fabric (NFa), and 5 types of nylon mesh were selected as the base materials for aluminum sputtering, and aluminum sputtering was performed to study IR thermal imaging, color difference, temperature change, and so on, and the relationship with infrared transmittance was assessed. The electrical conductivity was measured and the aluminum-sputtered nylon film demonstrated 25.6kΩ of surface resistance and high electrical conductivity. In addition, the electromagnetic wave shielding characteristics of the sputtering-treated nylon film samples were noticeably increased as a result of aluminum sputtering treatment as measured by the electromagnetic wave blocking characteristics. When NFi and NFa samples with single-sided sputtering were placed on the human body (sputtering layer faced the outside air) and imaged using IR thermographic cameras, the sputtering layer displayed a color similar to the surroundings, showing a stealth effect. Moreover, the tighter the sample density, the better the stealth function. According to the L, a, b measurements, when the sputtering layer of NFi and NFa samples faced the outside air, the value of a was generally high, thereby demonstrating a concealing effect, and the △E value was also high at 124.2 and 93.9, revealing a significant difference between the treated and untreated samples. This research may be applicable to various fields, such as the military wear, conductive sensors, electromagnetic wave shielding film, and others.