• Title/Summary/Keyword: NEP

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Changes of Atrial Natriuretic Peptide System in Rats with Puromycin Aminonucleoside-Induced Nephrotic Syndrome

  • Bae, Eun-Hui;Lee, Jong-Un;Ma, Seong-Kwon;Kim, Soo-Wan
    • The Korean Journal of Physiology and Pharmacology
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    • v.13 no.1
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    • pp.1-7
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    • 2009
  • Sodium retention is a hallmark of nephrotic syndrome. We investigated whether sodium retention is associated with changes of natriuretic peptide system at different stages (i.e., a sodium retaining stage and a compensatory stage) of nephrotic syndrome. At day 7 after PAN(puromycin aminonucleoside) injection, the urinary excretion of sodium was decreased, along with the development of ascites and positive sodium balance. The plasma and urinary ANP(atrial natriuretic peptide) immunoreactivities were increased. ANP mRNA expression was increased in the heart and kidney, whereas that of NPR(natriuretic peptide receptor)-A and NPR-C mRNA was decreased in the kidney. The expression of NEP was decreased in the kidney. At day 14, urinary excretion of sodium did not differ from the control. The plasma ANP level and heart ANP mRNA expression returned to their control values. The expression of ANP mRNA in the kidney was increased in association with increased urinary ANP immunoreactivities. The expression of NPR-A in the kidney became normal, whereas that of NPR-C kept decreased. The expression of NEP(neutral endopeptidase) remained decreased. These findings suggest that the increased renal ANP synthesis in association with decreased metabolism via NEP and NPR-C may play a compensatory role against the development of sodium retention in nephrotic syndrome. The decreased of NPR-A expression in the kidney may contribute to the ANP resistance at day 7. The subsequent recovery of NPR-A expression may play a role in promoting sodium excretion in later stage(at day 14).

Estimation of Ecosystem Metabolism Using High-frequency DO and Water Temperature Sensor Data in Daecheong Lake (고빈도 DO 및 수온 센서 자료를 이용한 대청호 생태계 신진대사 산정)

  • Kim, Sung-Jin;Chung, Se-Woong;Park, Hyungseok;Oh, Jungkuk;Park, Daeyeon
    • Journal of Korean Society on Water Environment
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    • v.34 no.6
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    • pp.579-590
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    • 2018
  • The lakes' metabolism bears important information for the assessment of the carbon budget due to the accumulation or loss of carbon in the lake as well as the dynamics of the food webs through primary production. A lake-scale metabolism is evaluated by Gross Primary Production (GPP), Ecosystem Respiration (R), and Net Ecosystem Production (NEP), which is the difference between the first two values. Methods for estimating GPP and R are based on the levels carbon and oxygen. Estimation of carbon is expensive because of the use of radioactive materials which requires a high degree of proficiency. The purpose of this study was to estimate Lake Daecheong ecosystem metabolism using high frequency water temperature data and DO measurement sensor, widely utilized in the field of water quality monitoring, and to evaluate the possibility of using the application method. High frequency data was collected at intervals of 10 minutes from September to December 2017 by installing a thermistor chain and a DO sensor in downstream of Daechung Dam. The data was then used to estimate GPP, R and NEP using the R public program LakeMetabolizer, and other metabolism models (mle, ols, kalman, bookkeep). Calculations of gas exchange coefficient methods (cole, crusius, heiskanen, macIntyre, read, soloviev, vachon) were compared. According to the result, Lake Daecheong has some deviation based on the application method, but it was generally estimated that the NEP value is negative and acts as a source of atmospheric carbon in a heterotrophic system. Although the high frequency sensor data used in this study had negative and positive GPP and R values during the physical mixing process, they can be used to monitor real-time metabolic changes in the ecosystem if these problems are solved.

Carbon balance and net ecosystem production in Quercus glauca forest, Jeju Island in South Korea

  • Jeong, Heon Mo;You, Young Han;Hong, Seungbum
    • Journal of Ecology and Environment
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    • v.46 no.3
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    • pp.250-258
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    • 2022
  • Background: To assess the carbon sequestration capacity and net ecosystem productivity (NEP) of Quercus glauca forests, we analyzed the net primary productivity (NPP), carbon storage, and carbon emission of soil in a Q. glauca forest on Jeju Island (South Korea) from 2016 to 2018. Results: The average carbon stock in the above- and below-ground plant biomass was 223.7 Mg C ha-1, while the average amount of organic carbon fixed by photosynthesis was 9.8 Mg C ha-1 yr-1, and the average NPP was 9.6 Mg C ha-1 yr-1. Stems and branches contributed to the majority of the above- and below-ground standing biomass and NPP. The average heterotrophic carbon emission from the soil was 8.7 Mg C ha-1 yr-1, while the average NEP was 1.1 Mg C ha-1 yr-1. Although the carbon stock, carbon absorption, and soil respiration values were higher than those reported in other oak forests in the world, the NEP was similar or lower. Conclusions: These results indicator that Q. glauca forests perform the role of a large carbon sink through the CO2 absorption in the plants in terms of carbon balance. And it is judged to be helpful as data for assessment of carbon storage and flux in the forests and mitigation of elevated CO2 in the atmosphere.

Measuring the Environmental Attitudes for National Park Visitors : Application of New Environmental Paradigm (국립공원(國立公園) 방문객(訪問客)의 자연환경태도(自然環境態度) 측정(測定) : New Environmental Paradigm의 적용(適用))

  • Han, Sang-Yoel
    • Journal of Korean Society of Forest Science
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    • v.89 no.5
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    • pp.598-608
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    • 2000
  • This study examined several characteristics such as the relationships between environmental attitudes and national park visitors' socio-economic characteristics, and between environmental attitudes and their travel motivations. Environmental attitude was measured using the modified New Environmental Paradigm(NEP) scale, where five response options existed(from strongly disagree to strongly agree). Data for this empirical analysis were obtained from 2,647 participants at six national parks-Sulaksan, Kayasan, Naeiangsan, Pookhansan, Taeanhaean, and Hanryohaesang. Results showed that most visitors gave a pro-NEP response ranging from neutral attitude to pro-environmentalism. Environmental attitudes correlated positively with education level, while, negatively with age. Environmental concern, also, generally correlated positively with 'rest' and 'health' motivators, while, negatively with 'socialization' and 'vacation' motivators. The findings of this study suggest that education is the most effective politic measure to lead pro-environmental concern for park visitors. And, given the nature of the relationship between environmental concern and visitors' motivation, park managers should be more careful handling with family and group visitors who have 'vacation' and 'socialization' motivators than 'rest' and 'health' motivators.

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A 145 GHz Imaging Detector Based on 65-nm RFCMOS Technology (65-nm RFCMOS공정 기반 145 GHz 이미징 검출기)

  • Yoon, Daekeun;Kim, Namhyung;Kim, Dong-Hyun;Rieh, Jae-Sung
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.24 no.11
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    • pp.1027-1033
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    • 2013
  • In this work, a D-band imaging detector has been developed in a 65-nm CMOS technology for high frequency imaging application. The circuit was designed based on the resistive self-mixing of MOSFET devices. The fabricated detector exhibits a maximum responsivity of 400 V/W and minimum NEP of 100 $pW/Hz^{1/2}$ at 145 GHz. The chip size is $400{\mu}m{\times}450{\mu}m$ including the probing pads and a balun, while the core of the circuit occupies only $150{\mu}m{\times}100{\mu}m$.

AKARI OBSERVATIONS OF THE FLUCTUATIONS OF THE NEAR-INFRARED BACKGROUND II

  • Seo, H.J.;Lee, H.M.;Matsumoto, T.;Jeong, W.S.;Lee, M.G.;Pyo, J.
    • Publications of The Korean Astronomical Society
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    • v.32 no.1
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    • pp.327-329
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    • 2017
  • We report a spatial fluctuation analysis of the sky brightness in the near-infrared from observations towards the north ecliptic pole (NEP) by AKARI at 2.4 and $3.2{\mu}m$. As a follow up study of our previous work on the Monitor field of AKARI, we used NEP deep survey data, which covered a circular area of about 0.4 square degrees, in order to extend fluctuation analysis at angular scales up to 1000". After pre-processing, additional correction procedures were done to correct time varying components and instrumental effects such as MUXbleed. To remove resolved objects, we applied $2{\sigma}$ clipping and point spread function (PSF) subtraction. We finally obtained mosaicked images which can be used for the study of various diffuse emissions in the near-infrared sky and found that there are spatial structures in the mosaicked images using a power spectrum analysis.