• Title/Summary/Keyword: NEC

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Gamma-Aminobutyric Acid and/or Carnitine Supplementation Alters Lipid and Some Immune Related Nutrient Levels in Mice

  • Soh, Ju-Ryoun;Cha, Youn-Soo
    • Preventive Nutrition and Food Science
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    • v.9 no.1
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    • pp.58-64
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    • 2004
  • This study investigated the effects of carnitine and/or ${\gamma}$ -aminobutyric acid (GABA) supplementation on lipid profiles and some immune related nutrient in mice. Balb/c male mice were orally treated with either an AIN-76 diet (Con), a control diet plus carnitine (CS, 0.5 g/kg bw), a control diet plus GABA (GS, 0.5 g/kg bw) or a control diet plus carnitine plus GABA (CGS, 0.25 g/kg bw, respectively) for 6 weeks. There were no significant differences in feed consumption, energy intake, body weight gain or feed efficiency ratio among the groups during the experimental period. However, abdominal fat deposits were smaller in CS, GS and CGS groups compared with the Con group. Serum and liver triglycerides also were lower in CS, GS and CGS and serum total cholesterol was significantly lower in the CGS group compared with the Con group. Serum LDL cholesterol was lower in the CGS group and liver HDL cholesterol was significantly higher in the CS group compared with Con group. In serum, stearic acid and selecholeic acid were lower, but arachidic acid was higher in the CS group. Liver stearic acid was higher but oleic acid lower in CGS group compared with Con group. In carnitine supplemented groups, serum and liver nonesterified carnitine (NEC), acidsoluble acylcarnitine (ASAC), total carnitine (TCNE) concentrations were higher in only the CS group, not CGS group. Serum vitamin A and E concentrations were not different among the groups. These results may suggest that carnitine and/or GABA supplementation improves lipid profiles in mice, but did not affect the immune-related nutrients that we measured under the experimental conditions of this study.

A Study on the Status of the National Election Commission Records Management (선거관리위원회의 기록관리 현황에 관한 연구)

  • Oh, Gye Youn;Yoo, Hosuon;Jeong, Him-Chan;Kim, Yong;Oh, Hyo-Jung
    • Journal of Korean Society of Archives and Records Management
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    • v.18 no.1
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    • pp.177-202
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    • 2018
  • This study examined the characteristics of the records produced by the National Election Commission, which is designated as a constitutional institution in Korea, and derived problems by analyzing the status of its records management. This paper suggests improvement plans based on the findings. First, it investigated records and their features since the National Election Commission has been in service. The differences between works in the field and legislation were analyzed through literature surveys and staff interviews. The improvement plans were presented in terms of systems, facilities, human resources, and services. In particular, this study suggests focusing on the production of a large amount of the same records of the National Election Commission.

Infrared thermographic imaging in patients with alopecia. (탈모 환자의 적외선 체열 진단상 안면부 체열 특성)

  • Yi, Tae-Hoo;Moon, Jung-Bae;An, Kyung-Eh;Lee, Hye-Jung
    • Journal of Oriental Medical Thermology
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    • v.5 no.1
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    • pp.78-86
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    • 2006
  • Objectives: To examine any potential relationships between the types of alopecia and the facial heat distribution in patients with alopecia Methods: 183 patients with alopecia participated in this study to provide facial heat distribution measured by the Infrared Thermography Scanner (ITS, Nec San-ei Instruments Ltd, Japan). The thermography scan was used in a light-and heat-protected room after 20 minutes’of resting period. 1.5m of distance maintained between the patients and ITS. Results: Specificity in the type of facial heat distribution was found as follow. 1. Types of facial heat distribution can be classified as T-type and diffused patterns. 2. There was a significant difference in the pattern of facial heat distribution among different types of alopecia (p=0.002): facial heat distribution appeared T-type in Androgenic Alopecia, Alopecia Areata, and Telogen Effluvium (71.3%, 85.7%, 70.4%), whereas diffused pattern was dominant in Seborrheic Alopecia(55.6%). 3. There was a significant difference in the pattern of facialheat distribution between men and women (p<0.001): While the T-type and diffused type were equally appeared in men (50.6%: 49.4%), T-type was dominant in women (88.0% vs. 12.0%). Conclusions: We conclude that the pattern of facial heat distribution differs depends on the types of alopecia and gender. These differences may provide useful information for the diagnosis and clinical therapy for this population.

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AN EXPERIMENTAL STUDY ON THE READABILITY OF THE DIGITAL IMAGES IN THE FURCAL BONE DEFECTS (디지털영상의 치근이개부 골손실 판독효과에 관한 실험적 연구)

  • Oh Bong-Hyeon;Hwang Eui-Hwan;Lee Sang-Rae
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.25 no.2
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    • pp.363-373
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    • 1995
  • The aim of this study was to evaluate and compare observer performance between conventional radiographs and their digitized images for the detection of bone loss in the bifurcation of mandiblar first molar. One dried human mandible with minimal periodontal bone loss around the first molar was selected and serially enlarged 17 step defects were prepared in the bifurcation area. The mandible was radiographed with exposure time of 0.12, 0.20, 0.25, 0.32, 0.40, 0.64 seconds, after each successive step in the preperation and all radiographs were digitized with IBM-PC/32 bit-Dx compatible, video camera (VM-S8200, Hitachi Co., Japan), and color monitor(Multisync 3D, NEC, Japan). Sylvia Image Capture Board for the ADC(analog to digital converter) was used. The obtained results were as follows: 1. In the conventional radiographs, the mean score of the readability was higher at the condition of exposure time with 0.32 second. Also, as the size of artificial lesion was increased, the readability of radiographs was elevated (P<0.05). 2. In the digital images, the mean score of the readability was higher at the condition of exposure time with 0.40 second. Also, as the size of artificial lesion was increased, the readability of digital images was elevated(P<0.05). 3. At the same exposure time, the mean scores of readibility were mostly higher in the digitized images. As the exposure time was increased, the digital images were superior to radiographs in readability. 4. As the size of lesion was changed, the digital images were superior to radiographs in detecting small lesion. 5. The coefficient of variation of mean score has no significant difference between digital images and radiographs.

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A QUANTITATIVE STUDY OF BONE DENSITY ON RADIOGRAM BY USING IMAGE ANALYZER (영상 분석장치를 이용한 골 흑화도의 정량적 평가에 관한 연구)

  • Choi Won-Jae;Kim Jae-Duk
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.25 no.2
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    • pp.521-533
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    • 1995
  • This study was performed to develop and evaluate the method to detect Quantitatively the serial changes in the size of artificial lesion in the spongious bone by automatic color image analyzer. 15 intraoral radiograms taken before and after endodontic treatment of 5 cases were used for contour line analysis. 30 intraoral radiograms taken by geometrically standardized apparatus before and after serially the formation of artificial lesions of 0.80, 1.20, 1.75, 2.00mm in diameter at the periapical area and interdental area of spongious bone were used. The analysis of image according to the variance of lesion size by 0.25, 0.35, 0.55, and 0.85mm serially was performed by the histogram and the color enhancement with subtraction. The images inputted by CCDcamera were digitized and analyzed by NEXUS QUBE program with NEC PC-9801 computer. The obtained results were as follows: 1. There was no reliability in the analysis of lesions by contour line 2 .. The mean difference of the grey scale at each pixel was 1 step between reference image and the corrected images. 3. In the analysis by histogram of the artificial lesion in spongeous bone, the change over 0.55mm in the mesiodistal size was detectable by the change of the numbers of pixel showing the change in grey scale. 4. In the analysis by histogram of the artificial lesion in spongeous bone, the change over 0.25mm in the buccolingual size was detectable by the change in grey scale. 5. By color enbancement with- subtraction, each lesion was able to be isolated and the change in it's mesiodistal size was detectable visually , but not in it's buccolingual size.

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A Study on the Analysis of Patent Information in the Apparel Design -Focused on International Patent Classification- (의류디자인 분야의 특허정보 분석 -국제특허분류를 중심으로-)

  • 이금희
    • The Research Journal of the Costume Culture
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    • v.11 no.6
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    • pp.835-851
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    • 2003
  • This study analyses patent information of apparel design using computer technology and researches the trend of patent application focused on International Patent Classification. In terms of trend by filling data, Patent application started first in 1974 and increased sharply in 1993 with 14 cases and increased to 25 cases in 2000. In case of Korea, they began somewhat late in 1996, but reached a similar level with the leading country in 2000. In terms of trend by applicant, Gerber Garment Technology, Inc. filed 7 cases TORAY IND INC, filed 6 cases Levi Strauss & Co. filed 4 cases, NEC HOME ELECTRONICS LTD filed 3 cases, TOYOBO CO LTD filed 3 cases. Japanese companies occupied 52% and United States's companies occupied 48%. In terms of trend by country, foreigner occupied 47% of the patents filed by United State. Japanese take up 10% of total patent of United States. Korean occupied 84% of total patent of Korea and foreigner, american occupied 16% of the patents filed by Korea. In regared to International Patent Classification, in the section level G filed 92 cases(53%). In class level, G06 marked the first place in United States, Japan, and Korea. In subclass level, G06F marksed the first place with 74 cases. G06T and A61B were regarded as the new technologies. The new technologies are representing the dimensions of garment or computer-rendered model, providing the virtual reality through the texture mapping, digital dressing room or virtual dressing, and performing or retriving display on a screen for the result of changing pattern ao dress design, The technologies of core patent are designing or producing custom manufactured item, providing or prealtering the data for pattern making and visually displaying, interactively generating or previewing of various articles.

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Exercise Self-Efficacy as a Mediator between Goal-Setting and Physical Activity: Developing the Workplace as a Setting for Promoting Physical Activity

  • Iwasaki, Yoshie;Honda, Sumihisa;Kaneko, Shuji;Kurishima, Kazuhiro;Honda, Ayumi;Kakinuma, Ayumu;Jahng, Doosub
    • Safety and Health at Work
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    • v.8 no.1
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    • pp.94-98
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    • 2017
  • Background: Physical activity (PA) is ranked as a leading health indicator and the workplace is a key setting to promote PA. The purpose of this study was to examine how goal-setting and exercise self-efficacy (SE) during a health promotion program influenced PA level among Japanese workers. Methods: Using a cross-sectional study design, we surveyed 281 employees. The short version of the International Physical Activity Questionnaire was used to assess PA level. Exercise SE was assessed using a partially modified version of Oka's exercise SE scale. Personal goals were assessed as the total numbers of "yes" responses to five items regarding "details of personal goals to perform PA". A mediational model was used to examine whether exercise SE mediates between the number of personal goals and PA level. Results: The mean age of the participants was 46.3 years, 76.2% were men, and the most common occupational category was software engineer (30.6%). The average PA level per week exceeded the recommended level in 127 participants (45.2%). One hundred and eighty-four participants (65.5%) set some form of concrete personal goal to perform PA. The relationship between the number of personal goals and PA level was mediated by exercise SE. Conclusion: Our study showed that exercise SE mediates goal-setting and increases PA. The results suggest that the components of PA promotion programs should be tailored to enhance participants' confidence in performing PA.

Large Cell Neuroendocrine Carcinoma of the Extrahepatic Bile Duct (간외담도에 발생한 신경내분비암종 1예)

  • Park, Ji Young;Jeon, Tae Joo
    • The Korean Journal of Gastroenterology
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    • v.72 no.6
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    • pp.318-321
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    • 2018
  • Primary neuroendocrine tumors originating from the extrahepatic bile duct are rare. Among these tumors, large cell neuroendocrine carcinomas (NECs) are extremely rare. A 59-year-old man was admitted to Sanggye Paik Hospital with jaundice that started 10 days previously. He had a history of laparoscopic cholecystectomy, which he had undergone 12 years previously due to chronic calculous cholecystitis. Laboratory data showed abnormally elevated levels of total bilirubin 15.3 mg/dL (normal 0.2-1.2 mg/dL), AST 200 IU (normal 0-40 IU), ALT 390 IU (normal 0-40 IU), and gamma-glutamyl transferase 1,288 U/L (normal 0-60 U/L). Serum CEA was normal, but CA 19-9 was elevated 5,863 U/mL (normal 0-37 U/mL). Abdominal CT revealed a 4.5 cm sized mass involving the common bile duct and liver hilum and dilatation of both intrahepatic ducts. Percutaneous transhepatic drainage in the left hepatic duct was performed for preoperative biliary drainage. The patient underwent radical common bile duct and Roux-en-Y hepaticojejunostomy for histopathological diagnosis and surgical excision. On histopathological examination, the tumor exhibited large cell NEC (mitotic index >20/10 high-power field, Ki-67 index >20%, CD56 [+], synaptophysin [+], chromogranin [+]). Adjuvant concurrent chemotherapy and radiotherapy were started because the tumor had invaded the proximal resection margin. No recurrence was detected at 10 months by follow-up CT.

INFRARED THERMOGRAPHIC ANALYSIS OF TEMPERATURE RISE ON THE SURFACE OF BUCHANAN PLUGGER (적외선열화상장치를 이용한 Buchanan plugger 표면의 온도상승 분석)

  • Choi, Sung-A;Kim, Sun-Ho;Hwang, Yun-Chan;Youn, Chang;Oh, Byung-Ju;Choi, Bo-Young;Juhng, Woo-Nam;Jeong, Sun-Wa;Hwang, In-Nam;Oh, Won-Mann
    • Restorative Dentistry and Endodontics
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    • v.27 no.4
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    • pp.370-381
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    • 2002
  • This study was performed to evaluate the temperature rise on various position of the Buchanan plugger, the peak temperature of plugger's type and the temperature change by its touching time of heat control spling. The heat carrier system 'System B' (Model 1005, Analytic Technologies, USA) and the Buchanan's plug-gers of F, FM, M and ML sizes are used for this study. The temperature was set to 20$0^{\circ}C$ which Dr. Buchanan's "continuous wave of condensation" technique recommended on digital display and the power level on it was set to 10. In order to apply heat on the Buchanan's pluggers, the heat control spring was touched for 1, 2, 3, 4 and 5 seconds respectively. The temperature rise on the surface of the pluggers were measured at 0.5 mm intervals from tip to 20 mm length of shank using the infrared thermography (Radiation Thermometer-IR Temper, NEC San-ei Instruments, Ltd, Japan) and TH31-702 Data capture software program (NEC San-ei Instruments, Ltd, Japan). Data were analyzed using a one way ANOVA followed by Duncan's multiple range test and linear regression test. The results as follows. 1. The position at which temperature peaked was approximately at 0.5 mm to 1.5 mm far from the tip of Buchanan's pluggers (p<0.001). The temperature was constantly decreased toward the shank from the tip of it (p<0.001). 2. When the pluggerss were heated over 5 seconds, the peak temperature by time of measurement revealed from 253.3$\pm$10.5$^{\circ}C$ to 192.1$\pm$3.3$^{\circ}C$ in a touch for 1 sec, from 218.6$\pm$5.$0^{\circ}C$ to 179.5$\pm$4.2$^{\circ}C$ in a touch for 2 sec, from 197.5$\pm$3.$0^{\circ}C$ to 167.5$\pm$3.7$^{\circ}C$ in a touch for 3 sec, from 183.7$\pm$2.5$^{\circ}C$ to 159.8$\pm$3.6$^{\circ}C$ in a touch for 4 sec and from 164.9$\pm$2.$0^{\circ}C$ to 158.4$\pm$1.8$^{\circ}C$ in a touch for 5 sec. A touch for 1 sec showed the highest peak temperature, followed by, in descending order, 2 sec, 3 sec, 4 sec. A touch for 5 sec showed the lowest peak temperature (p<0.001). 3. A each type of pluggers showed different peak temperatures. The peak temperature was the highest in F type and followed by, in descending order, M type, ML type. FM type revealed the lowest peak temperature (p<0.001). The results of this study indicated that pluggers are designed to concentrate heat at around its tip, its actual temperature does not correlate well with the temperature which Buchanan's "continuous wave of condensation" technique recommend, and finally a quick touch of heat control spring for 1sec reveals the highest temperature rise.

Frequency of Platelet Transfusions and Outcome in Neonates with Thrombocytopenia (혈소판 감소증이 있는 신생아에서 혈소판 수혈 횟수와 예후)

  • Lim, Suk-Hwan;Kook, Jin-Hwa;Cho, Chang-Yee;Choi, Young-Youn;Hwang, Tai-Ju
    • Clinical and Experimental Pediatrics
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    • v.45 no.8
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    • pp.961-966
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    • 2002
  • Purpose : We compared the underlying or associated diseases according to the frequency of platelet transfusions in neonates with thrombocytopenia to know the factors predicting which patients will require multiple platelet transfusions. We also compared mortality. Methods : A retrospective study was performed in 72 neonates who received the platelet transfusions in neonatal intensive care unit(NICU) between August 1996 and July 2001. Group I received one platelet transfusion and group II received two or more. We compared the frequency of underlying or assodiated diseases such as sepsis/disseminated intravascular coagulopathy(DIC), respiratory distress syndrome(RDS), intraventricular hemorrhage(IVH), patent ductus arteriosus (PDA), necrotizing enterocolitis(NEC), liver or renal disease, and mortality between two groups. Results : Of the 72 patients, 29(40.2%) received one and 43(59.7%) received two or more transfusions; 16(22.2%) received four or more. There were no statistically significant differences in gestational age, birth weight, sex, and maternal history between two groups. C-section rate was higher in group II(20.7% vs. 55.8%, P<0.05) and the incidence of PDA was higher in group I (55.2% vs. 30.2%, P<0.05). Otherwise, there were no statistically significant differences in the incidence of sepsis/DIC, RDS, IVH, RDS, CLD, NEC, liver or renal disease, pulmonary hemorrhage and hypoxic ischemic encephalopathy, and mortality between group I and group II. Conclusion : There was no significant difference in clinical morbidity and mortality according to the frequency of platelet transfusion in neonates with thrombocytopenia. Further study is needed to know the predicting factor for multiple platelet transfusions in neonates with thrombocytopenia.