• Journal of Plant Biology
• /
• 제38권1호
• /
• pp.55-62
• /
• 1995

벼(Oryza sativa L. cv. Kye Hwa) 성숙종자에서 유도한 배발생 세포(embryogenic cell, EC)의 동위효소 발현양상과 효소활성을 조사하였다. 배발생 캘러스로부터 확립된 EC 현탁배양은 세포가 둥글며 세포질이 충만한 세포들로 이루어졌으나 비배발생 세포(nonembryogenic cell, NEC)의 현탁배양은 크게 신장한 액포화된 세포들로 구성되었다. 이러한 EC와 NEC의 peroxidase, esterase, acid phosphatase 그리고 malate dehydrogenase의 동위효소 양상과 활성도를 분석한 결과 밴드의 수와 특이성 그리고 밴드 활성 등에 현저한 차이를 보여주었으며 또한 이들 동위효소의 효소 활성도 측정 결과 EC에서 훨씬 더 높게 나타났다. NEC에는 나타나지 않은 EC의 특이 밴드와 강한 밴드 활성 그리고 높은 효소 활성 등은 EC의 형태적, 분화능과의 관련성을 내포하고 있다. 이러한 결과들은 이들 효소의 특이 밴드들이 벼에서 EC의 생화학적 표지자로서 사용될 수 있음을 내포하고 있다.

• 한국정보디스플레이학회:학술대회논문집
• /
• 한국정보디스플레이학회 2004년도 Asia Display / IMID 04
• /
• pp.119-123
• /
• 2004

This paper describes low temperature poly-Si (LTPS) TFT system on glass (SOG) technology developed in NEC. High resolution SOG-LCDs such as a 230 ppi reflective type LCD, a 2.5", 333 ppi 2D/3D autostereoscopic LCD, and a 2.1" single voltage driven full integration LCD for mobile applications and a 0.9", XGA light valve for projectors are reviewed from the perspective of the high resolution technologies

• Neonatal Medicine
• /
• 제18권2호
• /
• pp.337-344
• /
• 2011

목적: 신생아 시기에 수술적 치료를 한 위장관계 질환과 저체중 출생아에서 발생 빈도가 높은 위장관계 질환에 대한 이해를 높이고자 한다. 방법: 2008년 1월부터 2010년 12월까지 부산대학교병원과 부산대학교 어린이병원 신생아실에 입원한 환아 중 위장관계 질환으로 진단되고 외과적 치료를 받은 125명과 괴사성 장염과 서혜부 탈장으로 진단받은 환아 40명을 대상으로 원인 질환 및 빈도, 출생력, 성별, 동반 기형과 혈청학적 결과를 살펴보았다. 결과: 괴사성 장염과 서혜부 탈장을 제외한 총 125명 환아 중에서 항문 직장 기형이 가장 흔하였고, 남성이 우세하였다. 24명(19.2%)에서 타기형이 동반되었고 수신증, 선천성 심장 기형이 많았으며, 항문 직장 기형에서는 43.9%에서 동반 기형이 있었다. 출생체중을 보면 괴사성 장염의 경우 76.0%가 1,500 g 미만으로 대부분을 차지하였다. 술 후 완전 장관 영양까지의 기간은 괴사성 장염이 평균 30.8일로 가장 길었다. 술 후 합병증은 담즙정체증, 패혈증과 유착 등이 있었다. 괴사성 장염을 제외한 위장관계 질환으로 수술적 치료를 받았던 환자들은 1.6%의 사망률을 보였으며 수술적 치료를 받은 괴사성 장염의 사망률은 18.8%였다. 괴사성 장염의 수술군에서 보존적 치료군보다 직접 빌리루빈이 의미있게 더 높았다. 결론: 수술적 치료를 받은 위장관 질환의 생존율은 높고 수술적 치료의 성과도 우수하였다. 괴사성 장염 환아 중 수술군에서 직접 빌리루빈이 유의하게 더 높았다.

• Clinical and Experimental Pediatrics
• /
• 제49권5호
• /
• pp.489-493
• /
• 2006

목 적 : 본 연구의 목적은 만삭아에서 신생아 괴사성 장염의 위험인자를 알고자 함이다. 방 법 : 1998년 1월 1일부터 2005년 8월 1일까지 본원 소아과 신생아실에 입원한 환아 중 신생아 괴사성 장염으로 진단된 20례와 각각의 경우에 대해 짝짓기 방식으로 선정된 건강한 만삭아 40례를 대상으로 병력지 검토를 통하여 후향적으로 조사되어 졌다. 결 과 : 괴사성 장염군의 평균 재태연령과 출생 체중은 38.42주와 2,915 g이었고 대조군은 38.61주와 3,148 g이었다. 대조군과 비교 하였을 때 신생아 괴사성 장염군 환아들에서 모체의 융모 양막염, 지연된 설사, 1분 아프가 점수 <7, 호흡기 문제, 선천성 심질환의 빈도가 유의하게 높았다(유의수준 <0.05). 반면 전자간증, 모체의 당뇨, 모체의 약물 남용, 태변 착색된 양수, 다혈구증, 교환 수혈의 빈도에는 유의한 차이가 없었다. 결 론 : 만삭아들의 대부분은 괴사성 장염이 발생하기 전에 선행하는 인자가 있다. 본 연구에서는 여러 가지 유발인자들 중에 지연된 설사가 가장 큰 관련성이 있는 것으로 나타났다.

• Applied Biological Chemistry
• /
• 제34권2호
• /
• pp.134-141
• /
• 1991

대두의 조직배양에서 배양기간중 생화학적 대사산물의 변화와 특성을 조사하기 위하여 개화후 15일된 미숙자엽을 채취하여 기내에서 3주간 배양하였다. 이때의 배양체를 embryogenic callus(EC)와 non-embryogenic callus(NEC)로 구분하였다. EC의 일부는 다시 3주간 계 대배양하여 root forming cultures(RFC)와 shoot forming cultures(SFC)로 구분하였으며, EC의 또 다른 일부는 원형질체의 분리에 사용되었으며, 분리된 원형질체는 4주간 배양하였다. 이때 유기된 배양체를 protoplasts로부터 유기된 embryogenic callus(PEC)와 non-embryogenic callus(PNEC)로 구분하였다. 각각의 배양체에 대하여 단백질 및 그 아미노산조성을 조사한 결과, 아미노산의 조성 은 NEC와 PNEC에서보다 EC와 PEC에 서 methionine의 함량이 현저히 낮은 반면, phenylalanine의 함량이 높았다. 단백질의 양상은 EC에서는 18KD, NEC에서는 22KD 정도에서 차이가 났다. 또한 각각의 배양체에 대한 peroxidase 동위 효소의 활성을 조사한 결과, EC와 PEC에서는 peroxidase isozyme A(piA)의 활성이 높게 나타났으며, RFC와 SFC에서는 peroxidase isozyme B(piB)의 활성이 높았다.

• 기술혁신연구
• /
• 제14권2호
• /
• pp.29-48
• /
• 2006

This paper analyzes organizational behavior of an established firm when disruptive innovation, a change in product architecture, occurs on a previous product. For the analysis, the paper analyzes and compares the behavior of an established fm through product trajectories between NEC (an established firm) and Toshiba (a new entrance) in the Japanese laptop computers industry. An established firm that has developed and produced a previous product is difficult in adapting to a disruptive innovation due to accumulated immense knowledge through a previous product. By using regression model in the product trajectory analysis, the paper analyzes the behavior of established firms. Product trajectory means a pattern of product strategy shown in a series of products. Two facts found in the paper are as follows. First, though NEC was able to develop a laptop computer at the same time with Toshiba, it was restricted by the resources of a previous product in the early stage. Second, possibility of teaming trap in the adapting process was found. The paper found the risk that too much commitment in one evolution stage would prohibit the adapting behavior in the next evolution stage.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• 제24권3호
• /
• pp.245-255
• /
• 2021

Necrotizing enterocolitis (NEC) is a disease with high morbidity and mortality that occurs mainly in premature born infants. The pathophysiologic mechanisms indicate that gastrointestinal dysbiosis is a major risk factor. We searched for relevant articles published in PubMed and Google Scholar in the English language up to October 2020. Articles were extracted using subject headings and keywords of interest to the topic. Interesting references in included articles were also considered. Network meta-analysis suggests the preventive efficacy of Bifidobacterium and Lactobacillus spp., but even more for mixtures of Bifidobacterium, Streptococcus, and Bifidobacterium, and Streptococcus spp. However, studies comparing face-to-face different strains are lacking. Moreover, differences in inclusion criteria, dosage strains, and primary outcomes in most trials are major obstacles to providing evidence-based conclusions. Although adverse effects have not been reported in clinical trials, case series of adverse outcomes, mainly septicemia, have been published. Consequently, systematic administration of probiotic bacteria to prevent NEC is still debated in literature. The risk-benefit ratio depends on the incidence of NEC in a neonatal intensive care unit, and evidence has shown that preventive measures excluding probiotic administration can result in a decrease in NEC.

• Nutritional Sciences
• /
• 제8권2호
• /
• pp.97-103
• /
• 2005

The goal of this study was to investigate abnotmalities in camitine metabolism present by determining blood camitine and lipid concentrations in Korean diabetic patients. The study subjects included 108 Korean diabetic patients (64 males and 44 females) who were hospitalized in Chonbuk National University Hospital and 27 subjects were also hospitalized as non-diabetic controls (10 males and 17 females). Glucose, total cholesterol, triglyceride (TG) and HDL-cholesterol in plasma were enzymatically assayed and insulin was measured by immunoradiometric assay. Nonesterified camitine (NEC), acid-soluble acylcarnitine (ASAC), and acid-insoluble acylcarnitine (AIAC) were determined by a modified radioisotopic method Glucose and insulin levels were significantly elevated in diabetic patients compared with controls. Total cholesterol was elevated in female but not male diabetic patients and triglycerides were elevated both in male and female diabetics. Plasma and urinary total carnitine (TCNE) were significantly elevated in diabetics as compared with normal controls. In male diabetics, NEC concentrations were significantly elevated above controls, but not in female subjects. Plasma NEC and TCNE concentrations were significantly increased in male diabetics, but significantly decreased in female diabetics. All urinary carnitine concentrations were significantly increased in diabetics as compared with controls. Urinary NEC concentrations were four times higher in male diabetics and three times higher in female diabetics than in controls. The ratios of serum and urinary acylcarnitine/NEC were also significantly higher in diabetics than in controls. This study suggested that there was a remarkable abnormality in lipid and carnitine metabolism in Korean diabetic patients, and the further study on carnitine metabolism and the effects of carnitine supplementation for Korean diabetic patients are needed.

• 한국화재소방학회:학술대회논문집
• /
• 한국화재소방학회 2002년도 추계학술대회논문집
• /
• pp.280-287
• /
• 2002

Most Technological laws of Korea are almost identical to those of Japan. Electricity was not introduced to Korea until lighting ceremony in Kyong-Bok palace observed in 1887. Since Korea was annexed to Japan in 1910, Korea have applied Japanese law and regulations made by Chosun government-general. And public works were under Japan control. Korea accepted adopted the power plants of America, codes of NESC, ASME / ANSI, MEMA while Japan accepted or adopted only IEC. Our generation distribution system takes American style while our consumer side takes Japanese style. As global trade system was transferred GATT into WTO, the technological standards, certification, construction and testing are in harmony internationally. The WTO / TBT agreement came in effect after 12th, April, 1979. The sections in the agreement require the members to exchange their own standards and codes for the harmonized ones by degree. The Korean distribution system has a strong resemblance to American system so that the internal engineers are confused in application of the relevant standards. IEC60364 and NEC are technologically similar but practically unconvertible because both have their different originality, that is to say Europe and USA. This paper deals with the fundamental elements of electrical safety system on review of IEC 60364 and NEC. This paper considers how engineers should apply IEC60364 and NFPA 70(NEC) based on all-the-way review of them.

• Advances in pediatric surgery
• /
• 제14권2호
• /
• pp.144-152
• /
• 2008

Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in the neonatal population. The aim of this study is to evaluate surgical indication and prognostic factors of NEC. Clinical data of seventy patients, diagnosed as NEC between January 2000 & January 2007, were reviewed retrospectively. Fifty-seven patients had medical treatment and 7 of them died. Thirteen patients who presented with pneumoperitoneum on plain abdominal film or were refractory to medical treatment received surgical treatment, and 5 of them died. All the expired 12 patients weighed less than 2500 g. Twenty out of seventy patients showed thrombocytopenia, and 11 patients of them died. The finding of pneumoperitoneum and thrombocytopenia could be the most important surgical indication. Prematurity, low birth weight and thrombocytopenia were related to a bad prognosis. NEC patients who presents with these findings must be considered for close observation and intensive care.