Prognostic Factors of Necrotizing Enterocolitis

신생아 괴사성 장염의 예후 인자에 관한 연구

  • Kang, Dong-Won (Department of Surgery, Sanggye Paik Hospital, College of Medicine, Inje University) ;
  • Gwak, Geum-Hee (Department of Surgery, Sanggye Paik Hospital, College of Medicine, Inje University) ;
  • Yang, Keun-Ho (Department of Surgery, Sanggye Paik Hospital, College of Medicine, Inje University) ;
  • Bae, Byung-Noe (Department of Surgery, Sanggye Paik Hospital, College of Medicine, Inje University) ;
  • Kim, Ki-Hwan (Department of Surgery, Sanggye Paik Hospital, College of Medicine, Inje University) ;
  • Han, Se-Whan (Department of Surgery, Sanggye Paik Hospital, College of Medicine, Inje University) ;
  • Kim, Hong-Joo (Department of Surgery, Sanggye Paik Hospital, College of Medicine, Inje University) ;
  • Kim, Young-Duk (Department of Surgery, Sanggye Paik Hospital, College of Medicine, Inje University) ;
  • Choi, Myeung-Jae (Department of Pediatrics, Sanggye Paik Hospital, College of Medicine, Inje University)
  • 강동원 (인제대학교 의과대학 상계백병원 외과학교실) ;
  • 곽금희 (인제대학교 의과대학 상계백병원 외과학교실) ;
  • 양근호 (인제대학교 의과대학 상계백병원 외과학교실) ;
  • 배병노 (인제대학교 의과대학 상계백병원 외과학교실) ;
  • 김기환 (인제대학교 의과대학 상계백병원 외과학교실) ;
  • 한세환 (인제대학교 의과대학 상계백병원 외과학교실) ;
  • 김홍주 (인제대학교 의과대학 상계백병원 외과학교실) ;
  • 김영덕 (인제대학교 의과대학 상계백병원 외과학교실) ;
  • 최명재 (인제대학교 의과대학 상계백병원 소아청소년과학교실)
  • Received : 2008.08.14
  • Accepted : 2008.10.27
  • Published : 2008.12.31

Abstract

Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in the neonatal population. The aim of this study is to evaluate surgical indication and prognostic factors of NEC. Clinical data of seventy patients, diagnosed as NEC between January 2000 & January 2007, were reviewed retrospectively. Fifty-seven patients had medical treatment and 7 of them died. Thirteen patients who presented with pneumoperitoneum on plain abdominal film or were refractory to medical treatment received surgical treatment, and 5 of them died. All the expired 12 patients weighed less than 2500 g. Twenty out of seventy patients showed thrombocytopenia, and 11 patients of them died. The finding of pneumoperitoneum and thrombocytopenia could be the most important surgical indication. Prematurity, low birth weight and thrombocytopenia were related to a bad prognosis. NEC patients who presents with these findings must be considered for close observation and intensive care.

Keywords