• 제목/요약/키워드: NEC

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Analysis of necrotizing enterocolitis and transfusion of red blood cell in very low birth weight preterm infants

  • Bak, Seon-Yeong;Lee, Sihyoung;Park, Jae-Hong;Park, Kyu-Hee;Jeon, Ji-Hyun
    • Clinical and Experimental Pediatrics
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    • 제56권3호
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    • pp.112-115
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    • 2013
  • Purpose: To investigate the association between necrotizing enterocolitis (NEC) and red blood cell transfusions in very low birth weight (VLBW) preterm infants. Methods: We studied were 180 VLBW preterm infants who were admitted to the neonatal intensive care unit of CHA Gangnam Hospital from January of 2006 to December of 2009. The subjects were divided into 2 groups: an NEC group (greater than stage II on the modified Bell's criteria) and a control group (less than stage II on the modified Bell's critieria). We defined red blood cell transfusion before NEC diagnosis as the frequency of transfusion until NEC diagnosis (mean day at NEC diagnosis, day 18) in the NEC group and the frequency of transfusion until 18 days after birth in the control group. Results: Of the 180 subjects, 18 (10%) belonged to the NEC group, and 14 (78%) of these 18 patients had a history of transfusion before NEC diagnosis. The NEC group received $3.1{\pm}2.9$ transfusions, and the control group received $1.0{\pm}1.1$ transfusions before the NEC diagnosis (P=0.005). In a multivariate logistic regression corrected for gestational age, Apgar score at 1 minute, the presence of respiratory distress syndrome, patent ductus arteriosus, premature rupture of membrane, disseminated intravascular coagulopathy and death were confounding factors. The risk of NEC increased 1.63 times (95% confidence interval, 1.145 to 2.305; P=0.007) with transfusion before the NEC diagnosis. Conclusion: The risk for NEC increased significantly with increased transfusion frequency before the NEC diagnosis.

곡물류의 형질전환 유도에 관한 연구 (IV) 벼 배발생 세포의 생화학적 특징 (Studies on the Transformation of Crop Plants. IV. Biochemical Characteristics of Embryogenic Callus in Rice)

  • 정병균
    • Journal of Plant Biology
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    • 제36권4호
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    • pp.377-382
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    • 1993
  • 벼(Oryza sativa L.) 캘러스는 2.0 mg/L 2,4-D와 0.5 mg/L kinetin이 첨가된 MS 배지에서 성숙종자로부터 유도되었으며 embryogenic callus(EC)와 nonembryogenic callus(NEC)는 색깔과 외부형태에 의해 경시적으로 선별되었다. EC와 NEC의 전체 단백질로부터 SDS-PAGE와 등전점 전기영동에 의한 전기영동적 분석은 EC와 NEC의 각각에 대해 특이적, 양적인 차이를 보여주었다. 또한 EC와 NEC의 2차원 전기영동 분석은 약 20여개 이상의 EC 특이단백질과 10여개의 NEC 특이 단백질 양상을 보여주었으며, 아울러 EC 특이적인 90, 65, 50 kD의 단백질은 microheterogeneity를 보여주는 반면, NEC에서는 분자량의 변이가 큰 일련의 산성 이질단백질군을 보여주었다.

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로타바이러스 감염이 관련된 신생아 괴사성 장염 (Rotavirus-associated neonatal necrotizing enterocolitis)

  • 서현주;정유진;박수경;최서희;이지혁;김묘징;장윤실;박원순
    • Clinical and Experimental Pediatrics
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    • 제52권1호
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    • pp.56-60
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    • 2009
  • 목적 : 본 연구에서는 로타바이러스와 관련된 신생아 괴사성 장염(RV+NEC)이 로타바이러스와 연관되지 않은 신생아 괴사성 장염(RV-NEC)과 서로 다른 경과 및 예후를 보이는지 알아보고자 하였다. 방 법 : modified Bell stage II 이상의 환아들을 monoclonal antibody-based enzyme immunoassay (EIA) 결과를 통해 8명의 RV+NEC군과 22명의 RV-NEC군으로 분류하였고 이 두군의 임상양상과 방사선소견 및 치료 결과를 후향적으로 조사하여 비교하였다. 결 과 : RV+NEC군에서 RV-NEC군보다 재태주령과 출생체중이 통계적으로 유의하게 더 높았다($33.5{\pm}3.3$ 주 vs $29.3{\pm}4.4$ 주; P=0.01). 두 군간의 C-반응성 단백질의 최고치, 혈소판 감소증, 장벽 내 공기와 장 천공의 비교에서는 차이가 없었으나 문맥 정맥 내 공기의 빈도는 RV+NEC군에서 유의하게 많았다(88% vs 9%; P<0.01). III 이상의 병기와 수술율 그리고 합병증과 사망률을 비교한 결과에서는 두 군 간에 차이를 보이지 않았다. 결 론 : 로타바이러스와 관련된 신생아 괴사성 장염은 로타바이러스와 연관되지 않은 신생아 괴사성 장염에 비해 더 높은 재태주령과 출생체중을 가지나 질환의 중증도와 결과 면에서는 차이가 없었다.

High-visibility 2D/3D LCD with HDDP Arrangement and its Optical Characterization Methods

  • Uehara, Shin-Ichi;Hiroya, Tsutomu;Kusanagi, Hidenori;Shigemura, Kouji;Asada, Hideki
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2008년도 International Meeting on Information Display
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    • pp.147-150
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    • 2008
  • We have developed a 3.1-inch diagonal 2D/3D LCD with a novel pixel arrangement, called HDDP (Horizontally Double-Density Pixels), for high-quality 3D images. We have improved 3D visibility by broadening the 3D viewing zone where high-quality images can be seen, and we propose optical characterization methods which can evaluate the high-visibility autostereoscopic displays correctly.

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An update on necrotizing enterocolitis: pathogenesis and preventive strategies

  • Lee, Jang-Hoon
    • Clinical and Experimental Pediatrics
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    • 제54권9호
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    • pp.368-372
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    • 2011
  • Necrotizing enterocolitis (NEC) is one of the most critical morbidities in preterm infants. The incidence of NEC is 7% in very-low-birthweight infants, and its mortality is 15 to 30%. Infants who survive NEC have various complications, such as nosocomial infection, malnutrition, growth failure, bronchopulmonary dysplasia, retinopathy of prematurity, and neurodevelopmental delays. The most important etiology in the pathogenesis of NEC is structural and immunological intestinal immaturity. In preterm infants with immature gastrointestinal tracts, development of NEC may be associated with a variety of factors, such as colonization with pathogenic bacteria, secondary ischemia, genetic polymorphisms conferring NEC susceptibility, anemia with red blood cell transfusion, and sensitization to cow milk proteins. To date, a variety of preventive strategies has been accepted or attempted in clinical practice with regard to the pathogenesis of NEC. These strategies include the use of breast feeding, various feeding strategies, probiotics, prebiotics, glutamine and arginine, and lactoferrin. There is substantial evidence for the efficacy of breast feeding and the use of probiotics in infants with birth weights above 1,000 g, and these strategies are commonly used in clinical practice. Other preventive strategies, however, require further research to establish their effect on NEC.

Better Management (Risk and Change) through NEC Contracts in Hong Kong

  • TUNG, Chu Hoi;MEMON, Shoeb Ahmed;JAVED, Arshad Ali
    • 국제학술발표논문집
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    • The 8th International Conference on Construction Engineering and Project Management
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    • pp.323-330
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    • 2020
  • Project delays, cost overruns, and disputes are becoming a norm for the construction industry in Hong Kong. Researchers argue that the inability of traditional contracts to manage risk and associated changes are perhaps the main points of contention. The Institution of Civil Engineers published a new engineering contract (NEC), NEC4 Suite of Contracts in this to facilitate better risk management through collaborative culture in construction projects. NEC aims to increase the chances of project success thought its flexible nature of contracts, 'simple' and 'clearly written' documents and provision for the incentive by adopting a better management approach. This paper focuses on traditional and NEC contracts to compare risk management and change management aspects. Through literature review and preliminary interviews with three industry professionals, the paper is exploring how a change in traditional contracts can recuperate from disaster. Our interviewees in this work have extensive experience in traditional as well as in NEC contracts. The results suggest a proactive risk management provisions in NEC contracts does make a difference to avoid later escalation of issues. Whereas, management of change helps streamline all identified issues through a structured process without going in mediation or litigation. NEC, with its new approach to collaborative working, allows partners to be vigilant, yet gratifying in the project process.

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The relation between serum levels of epidermal growth factor and necrotizing enterocolitis in preterm neonates

  • Ahmed, Heba Mostafa;Kamel, Nsreen Mostafa
    • Clinical and Experimental Pediatrics
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    • 제62권8호
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    • pp.307-311
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    • 2019
  • Purpose: Necrotizing enterocolitis (NEC) is one of the most serious complications of prematurity. Many risk factors can contribute to the development of NEC. The epidermal growth factor (EGF) plays a major role in intestinal barrier function, increases intestinal enzyme activity, and improves nutrient transport. The aim of this study was to assess the role of epidermal growth factor in the development of NEC in preterm neonates. Methods: In this study, 130 preterm neonates were included and divided into 3 groups, as follows: group 1, 40 preterm neonates with NEC; group 2, 50 preterm neonates with sepsis; and group 3, 40 healthy preterm neonates as controls. The NEC group was then subdivided into medical and surgical NEC subgroups. The serum EGF level was measured using enzyme-linked immunosorbent assay. Results: Serum EGF levels (pg/dL) were significantly lower in the NEC group (median [interquartile range, IQR], 9.6 [2-14]) than in the sepsis (10.1 [8-14]) and control groups (11.2 [8-14], P<0.001), with no significant difference between the sepsis and control groups, and were positively correlated with gestational age (r=0.7, P<0.001). A binary logistic regression test revealed that low EGF levels and gestational ages could significantly predict the development of NEC. The receiver-operating characteristic curve for EGF showed an optimal cutoff value of 8 pg/mL, with 73.3% sensitivity, 98% specificity, and an area under the curve of 0.92. Conclusion: The patients with NEC in this study had significantly lower serum EGF levels (P<0.001), which indicated that EGF could be a reliable marker of NEC in preterm neonates.

470 x 235ppi poly-Si TFT LCD for High-Resolution 2D and 3D Autostereoscopic Display

  • Uehara, Shin-Ichi;Ikeda, Naoyasu;Takanashi, Nobuaki;Iriguchi, Masao;Sugimoto, Mitsuhiro;Matsuzaki, Tadahiro;Asada, Hideki
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2004년도 Asia Display / IMID 04
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    • pp.783-786
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    • 2004
  • We have developed a 470 x 235ppi poly-Si TFT LCD with a novel pixel arrangement, called HDDP (Horizontally Double-Density Pixels), for high-resolution 2D and 3D autostereoscopic display. 3D image quality is especially high in a lenticular-lens-equipped 3D mode because both horizontal resolution and vertical resolution are high, and because these resolutions are equal. 3D and 2D images can be displayed simultaneously in the same picture. In addition, 3D images can be displayed anywhere and 2D characters can be made to appear at different depths with perfect legibility. No switching of 2D/3D modes is necessary, and the design's thin and uncomplicated structure makes it especially suitable for mobile terminals.

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WTO/TBT 협정에 준한 전기설비의 IEC 60364와 NFPA70(NEC)의 비교적용에 관한 연구 (Research on the Comparison and Application of IEC60364 & NFPA70(NEC) according to WTO/TBT agreement)

  • 정용기;곽희로;남택주
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2001년도 춘계학술대회 논문집 전력기술부문
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    • pp.140-143
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    • 2001
  • As global trade system transferred GATT into WTO, the harmonization of technological standards, certification, construction, testing is the trend of world. This drift is based on WTO / TBT agreement coming. In effect after 12th, April, 1979. For Korea, the distribution system has a strong resemblance to American system so that engineers are confused in adopting standards. IEC60364 and NEC are in part similar but unconvertible because IEC 60364 originated from Europe while NEC originated from USA. This thesis deals with the fundamental elements of electrical safety system with comparing IEC 60364 with NEC. It serves as a guide how to apply standards when engineers select electrical installations.

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DSP를 사용한 4채널용 ADPCM CODEC의 실시간 구현에 관한 연구 (Implementation of a 4-Channerl ADPCM CODEC Using a DSP)

  • 이의택;이강석;이상욱
    • 대한전자공학회논문지
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    • 제22권5호
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    • pp.29-38
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    • 1985
  • 본 논문에서는 파형 코우딩 방식에 속하는 ADPCM을 NEC 7720 DSP를 사용하여 간단하고 성능이 우수하며 유연성 (flexibility)이 뛰어난 ADPCM cosec을 실시간 구현을 하였다. ADPCM 알고리듬은 적응 양자기와 1차의 고정예측기를 사용하였으며 프로그램을 최적화하여 하나의 NEC 7720으로 4 채널을 동시에 부호화 또는 복호화 할 수 있도록 하였다. 실제 전화음성과 RC 정형 Gaussian 잡음 및 1004Ht 정현파를 사용한 컴퓨터 시뮬레이tus으로부터 NEC 7720의 연산 정확도를 조사하였으며, SNR 및 청각조사로 부터 알고리듬 수행에 필요한 값들을 결정하였다. NEC 7720의 소프트웨어는 real-time hardware emulator로 실시간 동작을 확인하였는데 부호기에서 1샘플을 부호화하는데 최대 23. 25μs가 걸리고 4 채널을 모두 부호화하는데 113.5μs가 필요하였으며, 복호기에서는 각각 24. 75μs와 119. 5μs가 소요되었다.

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