• 인지과학
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• 제21권4호
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• pp.535-557
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• 2010

이중 부등호를 이용한 여러 실험을 통해 부적 일치 효과(negative compatibility effect: NCE)가 일관적으로 관찰되었다. 그러나 왜 이 현상이 발생하는가에 대해서는 몇 가지 서로 다른 가설이 제기되어 왔다. 본 연구에서는 부적 일치 효과의 발생 원인으로 가정되어 온 자동 억제, 정보의 업데이트 및 하향적 통제 등과 같은 요인들의 타당성을 확인하고자 하였다. 색이 다른 이중 부등호로 구성된, 차폐된 점화자극과 목표자극의 배열에 대해서 목표자극인 부등호의 방향에 대해 판단하는 경우에, 참가자들은 부등호의 방향과 손의 반응이 일관적인 과제 (실험 1), 부등호의 방향과 손의 반응이 반대인 과제 (실험 2)에서는 물론, 색 반응 과제 (실험 3) 에서도 방향에 근거한 부적 일치 효과를 나타냈다. 이 결과는 부적 일치효과의 주된 원인이 지각적 우세성이나 자극과 반응 사이의 본질적 속성에서 기인할 수 있음을 시사한다.

• Journal of Microbiology and Biotechnology
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• 제29권8호
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• pp.1281-1287
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• 2019

Nattokinase (NK, E.C. 3.4.21.62) is a serine protease produced by Bacillus subtilis natto that shows promise for the treatment of thrombotic disease. In this study, we assessed the effects of NK on the development of hepatocellular carcinoma (HCC), a principal malignancy of the liver that causes morbidity and mortality worldwide. Crude extracts of NK (NCE) were isolated from fermentation medium by centrifugation and separated into three fractions (<10 K, 100~30 K and >30K). Orthotopic HCC mouse models were established and NCE was administered by oral gavage. H&E staining was performed to examine the pathology of HCC livers. Immunohistochemistry and immunofluorescence were used to evaluate FOXM1, CD31, CD44 and vimentin expression in the liver. Compared to PBS groups, NCE increased the survival rates of HCC-bearing mice to 31% and decreased ascites. Low-intensity ultrasound imaging showed that the hypoechoic mass area was lower in NCE-treated mice and that tumor growth significantly decreased. IHC staining showed that the expression of FOXM1 was inhibited by NCE treatment. Immunofluorescence results revealed lower levels of CD31, CD44 and vimentin in the NCE groups. Taken together, these data demonstrate that NCE from Bacillus subtilis natto improves survival and inhibits tumor growth in HCC mice.

• 의료법학
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• 제14권2호
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• pp.261-280
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• 2013

Recently several hospitals have established a new nursing position so called, 'the nurse in charge of education (NCE).' The job description of NCE is to give a detail explanation on examination or test introduced to patients or a guide for those who are not familiar to hospital facilities at the out-patients level. The motivation of NCE position is the quality improvement in patient education on the sophisticated procedures or the follow up care for medical purposes to improve their compliances, as well in delivering services for outpatients or visitors in more informative and efficient way. The application of NCEA has been turned out positive and effective in patient satisfaction and unit management. However, special attention is brought to the scope and depth of the contents of education delivered by NCE which might overlap with the duty of physicians by the Medical Act. It is needed to clarify the role and job description of NCE in the context of Medical Act. The engagement of NCE to the Advanced Nursing Practitioner (ANP) is one of the possible solutions for a duty charge on patient education since ANP is a legislatively official position with higher license of RN at master level. Further discussion is needed to elaborate and arrange the details on the scope and content of patent education among health science professionals including RN, ANP and physicians.

• Journal of Electrical Engineering and Technology
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• 제9권1호
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• pp.90-97
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• 2014

Nash Cournot Equilibrium (NCE) has been widely used in a competitive electricity market to analyze generation firms' strategic production quantities. Congestion on a transmission network may lead to a mixed strategy NCE. Mixed strategy is complicated to understand, difficult to compute, and hard to implement in practical market. However, Stackelberg model based equilibrium does not have any mixed strategy, even under congestion in a transmission line. A guide to understanding mixed strategy equilibrium is given by analyzing a cycling phenomenon in the players' best choices. This paper connects the concept of leader-follower in Stackelberg model with relations between generation firms on both sides of the congested line. From the viewpoint of social welfare, the surplus analysis is presented for comparison between the NCE and the Stackelberg equilibrium (SE).

• Investigative Magnetic Resonance Imaging
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• 제25권4호
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• pp.209-217
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• 2021

Magnetic resonance angiography (MRA) plays an important role in accurate diagnosis and appropriate treatment planning for patients with arterial disease. Contrast-enhanced (CE) MRA is fast and robust, offering hemodynamic information of arterial flow, but involves the risk of a side effect called nephrogenic systemic fibrosis. Various non-contrast-enhanced (NCE) MRA techniques have been developed by utilizing the fact that arterial blood is moving fast compared to background tissues. NCE MRA is completely free of any safety issues, but has different drawbacks for various approaches. This review article describes basic principles of CE and NCE MRA techniques with a focus on how to generate angiographic image contrast from a pulse sequence perspective. Advantages, pitfalls, and key applications are also discussed for each MRA method.

• ETRI Journal
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• 제34권5호
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• pp.775-778
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• 2012

We propose integrating random network coding with the Enhanced On-Demand Multicast Routing Protocol (E-ODMRP). With the Network Coded E-ODMRP (NCE-ODMRP), we present a framework that enables a seamless integration of random linear network coding with conventional ad hoc multicast protocols for enhanced reliability. Simulation results show that the NCE-ODMRP achieves a nearly perfect packet delivery ratio while keeping the route maintenance overhead low to a degree similar to that of the E-ODMRP.

• 한국항해항만학회지
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• 제36권5호
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• pp.409-418
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• 2012

컨테이너 선사들은 세계경제의 불황과 고유가가 지속되고 있는 상황에서 선박운영비용을 낮추기 위한 다각적인 노력들을 전개하고 있다. 이러한 상황에서, Grand Alliance는 극동 북미서안 서비스인 CCX와 극동 북미동안 서비스인 NCE에 서비스별 선박추가 투입대신에 Dedicated Feeder 투입을 하기로 결정하였다. 즉, 기간항로의 선박이 북중국항만에 기항하지 않고 환적항인 부산항에서 Feeder선을 통하여 환적 운송하게 된다. 본 연구에서는 전용피더 서비스 도입을 통한 환적의 경제성 효과를 확인하기 위하여 Grand Alliance 컨테이너 서비스의 실제 운영 자료에 대해 분석하였다. 이와 같은 전략을 통해 Grand Alliance의 'NCE, 'CCX'항로는 기간항로에 투입되는 선박의 감속운항이 가능하게 되어 선박 운영비의 절감 효과를 보이고 있다.

• 한국미생물생명공학회:학술대회논문집
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• 한국미생물생명공학회 2001년도 Proceedings of 2001 International Symposium
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• pp.95-95
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• 2001

• 과학기술정책
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• 제13권6호통권144호
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• pp.40-53
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• 2003

• 대한핵의학회지
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• 제26권1호
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• pp.127-132
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• 1992

Colloidal $^{32}P$ chromic phosphate is used to prevent hepatic metastasis from colorectal cancer. It is speculated that the intravenous injection of colloidal $^{32}P$ chromic phosphate can cause genotoxicity. To evaluate the genotoxicity of intravenously injected colloidal $^{32}P$ chromic phosphate, authors performed a micronuclei test in mice bone marrow. Mice (ICR strain, $25\sim30g$) were divided to 4 groups: control, group 1 (19.166 KBq/g, usual therapeutic dose in human), group 2 (191.66 KBq/g), and group 3 (1916.6 KBq/g). Five mice of each group were sacrificed at days 1, 2, 3, 5, 7 and 14. Bone marrow were smeared and stained with Wright-Giemsa method. One thousand polychromatic erythrocytes (PCE) and normochromatic erythrocytes (NCE) were counted under the light microscope, and the number of micronucleated PCEs and NCEs were recorded. The frequency of micronuclei in PCE and NCE in the control group was $0.3{\pm}0.06%\;and\;0.45{\pm}0.10%$, respectively. At group 1, frequency of micronuclei is not different from the control. However, frequencies of micronuclei in PCE at groups 2 and 3 were significantly increased from day 1 and persisted to day 14. The frequency of micronuclei in NCE was increased only at group 3. In conclusion, the frequency of micronuclei increases as the dose of colloidal $^{32}P$chromic phosphate increases, while micronuclei was not induced at the usual therapeutic dose. And the frequency of micronuclei persistently elevated for 14 days in the cases of higer doses.