• Molecules and Cells
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• 제41권12호
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• pp.993-999
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• 2018

One of the most interesting findings from genome-wide expression analysis is that a considerable amount of noncoding RNA (ncRNA) is present in the cell. Recent studies have identified diverse biological functions of ncRNAs, which are expressed in a much wider array of forms than proteins. Certain ncRNAs associated with diseases, in particular, have attracted research attention as novel therapeutic targets and diagnostic markers. BC200 RNA, a 200-nucleotide ncRNA originally identified as a neuron-specific transcript, is abnormally over-expressed in several types of cancer tissue. A number of recent studies have suggested mechanisms by which abnormal expression of BC200 RNA contributes to the development of cancer. In this article, we first provide a brief review of a recent progress in identifying functions of BC200 RNA in cancer cells, and then offer examples of other ncRNAs as new therapeutic targets and diagnostic markers for human cancer. Finally, we discuss future directions of studies on BC200 RNA for new cancer treatments.

• 한국생산제조학회지
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• 제7권1호
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• pp.82-88
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• 1998

It is very important to test linear cycle positioning accuracy of NC lathes as it affect all other machines machined by them in industries. For example, if the linear positioning accuracy of x or z-axis directions is bad, the size of works will be wrong and the change-ability will be bad in the assembly of machine parts. In this paper , measuring systems are organized to measure linear displacement of ATC(Automatic tool changer) of NC lathe using laser interferometer, magnescale and tick pulses coming out from computer in order to get data at constant time intervals from the sensors, And each set of data gotten from test is expressed to a plots by computer treatment and the results of linear positioning error motion is estimated to numerics by statistical treatments.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2000년도 추계학술대회 논문집
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• pp.120-123
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• 2000

It is well known, for many years, that deep drawability can be improved by applying variable blank holding force. To apply variable blank holding force during cup during, we set up pressure controlling system on experimental hydraulic press, and the pressure control system is often called NC(Numerically Controlled) cushion system Using the NC cushion system we compared the drawability of square steel cups with NC cushion and that with conventional cushion. The results show drawability is greatly improved when the pressure control curve is designed in a S-shaped curve. This paper includes design details of the NC cushion system and experimental analysis of drawability with experimental NC cushion system.

• 한국공작기계학회논문집
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• 제14권5호
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• pp.21-26
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• 2005

It is important to measure the rotational accuracy of NC lathe spindle as it affects to the qualities of all machines machined by the NC lathe using in industries. The bad rotational accuracy of NC lathe spindle are caused mainly by wearness of the spindle in using and quality of spindle when machining and using low level bearings. It occurs especially in case of NC lathes because the cutting force acting to work-piece act on one side to the spindle not to both sides symmetrically. Therefore in this study, constructing experimental appratus for measuring of rotational accuracy by using eddy current type gap sensors, converters, screw terminal, data acquisition board inserted in computer and software f3r data acquisition, DT VEE ver. 5.0 and then error data acquired in the rotational accuracy test of NC lathe spindle are analysed in plots and statistical treatments.

• Nuclear Engineering and Technology
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• 제30권5호
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• pp.424-434
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• 1998

RELAP5/Mod3.1 code was assessed with the semiscale experiment S-NC-3, and S-NC-4, which simulated the two-phase natural circulation and reflux condensation for the SBLOCA of PWR, respectively . Test S-NC-3 and S-NC-4 calculation results showed that RELAP5/Mod3.1 quite well describes the influence of steam generator secondary side heat transfer degradation on both two-phase natural circulation and reflux condensation. A comparison between the calculated and measured two-phase mass flow rate in test S-NC-3 shows good agreement for primary mass inventory more than 92%. And RELAP5/Mod3.1 have a good mass flow rate prediction capability for the transient such as S-NC-4 except some flow oscillations. The reflux flow rate for S-NC-4 test is under predicted, and the overall results verify that the correct prediction of the reduced liquid level appears to be required for the correct calculation of the overall phenomena.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2005년도 ICCAS
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• pp.438-443
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• 2005

Handy paint rollers with simple or no patterns are generally used to transcribe its design to a wall just after painting. However, the types of the patterns are limited to several conventional ones, so that interior planners' or decorators' demands are gradually tending to getting attractive roller designs. In order to obtain abundant kinds of the roller designs, a new advanced 3D machining method should be established for cylindrical models. In this paper, a post-processor that can generate suitable NC data is proposed for multi-axis NC machine tools with a rotary unit. The 3D machining system with the post-processor is also presented for an attractive interior decorating. The machining system allows us to easily transcribe the relief designs from on a flat model to on a cylindrical model. The effectiveness of the proposed 3D machining system using the post-processor is demonstrated through some machining experiments.

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 1998년도 춘계학술대회 논문집
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• pp.165-171
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• 1998

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 1999년도 추계학술대회 논문집 - 한국공작기계학회
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• pp.27-33
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• 1999

In order to regulate cutting force at a desired level during NC lathe process, a feedrate override Adaptive Control Constraint system was developed. Nonlinear model of the cutting process was linearized as an adaptive model with a time varing process parameter. Performance of the ACC system was confirmed on the NC lathe equipped with the developed NC system through a large amount of experiment.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 제36회 하계학술대회 논문집 C
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• pp.1900-1902
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• 2005

본 연구에서는 scanning probe microscopy(SPM)을 이용하여 국소영역에서 silicon nanocrystal(Si NC)의 전기적 특성을 분석하였다. Si NCs은 압축된 silicon powder를 laser로 분해하는 laser ablation 방식으로 제조되었고, sharpening oxidation 과정을 통하여 Si NC 주변에 oxide shell을 형성시켰다. 이 과정에서 Si NCs은 $10{\sim}50 nm$의 크기와 약 $10^{11}/cm^2$의 밀도로 $SiO_2$층에 증착되었다. SPM의 conducting tip을 통하여 전하는 각각의 Si NC로 주입되게 되고, 이로 인하여 발생하는 SCM image와 dC/dV curve의 변화를 통하여 Si NC에서 전하 거동을 모니터 하였다. 또한 국소영역에서 Si NC의 전기적 특성을 MOS capacitor 구조에서의 C-V 특성과 비교 분석하였다.

• JSTS:Journal of Semiconductor Technology and Science
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• 제8권2호
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• pp.111-114
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• 2008

We studied the influence of nanocrystalline silicon (nc-Si) thin film thickness on top gate nc-Si thin film transistor (TFT) fabricated at $180^{\circ}C$. The nc-Si thickness affects the characteristics of nc-Si TFT due to the nc-Si growth similar to a columnar. As the thickness of nc-Si increases from 40 nm to 200 nm, the grain size was increased from 20 nm to 40 nm. Having a large grain size, the thick nc-Si TFT surpasses the thin nc-Si TFT in terms of electrical characteristics such as field effect mobility. The channel resistance was decreased due to growth of the grain. We obtained the experimental results that the field effect mobility of the fabricated devices of which nc-Si thickness is 60, 90 and 130 nm are 26, 77 and $119\;cm^2/Vsec$, respectively. The leakage current, however, is increased from $7.2{\times}10^{-10}$ to $1.9{\times}10^{-8}\;A$ at $V_{GS}=-4.4\;V$ when the nc-Si thickness increases. It is originated from the decrease of the channel resistance.