• Molecules and Cells
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• v.42 no.5
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• pp.379-385
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• 2019

Non-coding RNAs (ncRNAs) comprise various RNA species, including small ncRNAs and long ncRNAs (lncRNAs). ncRNAs regulate various cellular processes, including transcription and translation of target messenger RNAs. Recent studies also indicate that ncRNAs affect organismal aging and conversely aging influences ncRNA levels. In this review, we discuss our current understanding of the roles of ncRNAs in aging and longevity, focusing on recent advances using the roundworm Caenorhabditis elegans. Expression of various ncRNAs, including microRNA (miRNA), tRNA-derived small RNA (tsRNA), ribosomal RNA (rRNA), PIWI-interacting RNA (piRNA), circular RNA (circRNA), and lncRNA, is altered during aging in C. elegans. Genetic modulation of specific ncRNAs affects longevity and aging rates by modulating established aging-regulating protein factors. Because many aging-regulating mechanisms in C. elegans are evolutionarily conserved, these studies will provide key information regarding how ncRNAs modulate aging and lifespan in complex organisms, including mammals.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.22 no.5
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• pp.852-858
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• 2013

In numerical control (NC) machining, a machining error in equipment generally occurs for a variety of reasons. If there is a change in direction in the NC code, the characteristics of the automatic acceleration or deceleration function cause an overlap of each axis of the acceleration and deceleration zones, which in turn causes a shift in the actual processing path. Many studies have been conducted for error calibration of the edge as caused by automatic acceleration or deceleration in NC machining. This paper describes a geometric interpretation of the shape and processing characteristics of the operating NC device. The paper then describes a way to determine a feedrate that achieves the desired tolerance by using linear and parabolic profiles. Experiments were conducted by the validate equations using a three-axis NC machine. The results show that the machining errors were smaller than the machine resolution. The results also clearly demonstrate that the NC machine with the developed system can successfully predict machining errors induced with a change in direction.

• Journal of the Korean Society for Precision Engineering
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• v.19 no.2
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• pp.26-32
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• 2002

• Journal of Animal Science and Technology
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• v.66 no.1
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• pp.93-102
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• 2024

This study investigated the effect of dietary supplementation with phytase on growth performance, fecal excretion, and compost nutrition on broilers fed available phosphorus (avP)- and calcium (Ca)-deficient diets. A total of 750 one-day-old broiler chicks were randomly divided into five dietary groups having ten replications in a floor house. Diets of the groups were formulated with positive control (PC), negative control (NC; low avP and Ca), and NC supplemented with phytase levels; 500 (NC500), 1,000 (NC1000), and 1,500 FTU/kg (NC1500). A three-phase feeding program was used in the trial. Average daily gain (ADG) and average daily feed intake (ADFI) in the groups fed diets supplemented with phytase were significantly (p < 0.05) higher than those fed NC and the increase was equivalent to those fed PC. Serum levels of Ca and phosphorus (P) were higher (p < 0.05) in broilers fed NC1000 and NC1500 than in those fed NC. Interleukin (IL) level was the lowest in the group fed NC. Plasma myo-inositol (INS) concentrations in the NC1500 group were higher (p < 0.05) than PC, NC, and NC500 groups. Crude protein (CP) excretion was notably (p < 0.05) lower in the NC1500 group than in PC and NC groups. A lower (p < 0.05) concentration of P₂O₅ was observed in compost from the group fed NC1500 than the groups fed PC and NC. Accordingly, we suggest that phytase supplementation in lower avP and Ca levels of broiler diet can improve their productive performance and reduce environmental pollution.

• Structural Engineering and Mechanics
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• v.14 no.5
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• pp.595-610
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• 2002

This paper presents an efficiency of various non-conforming (NC) modes in development of a series of new finite elements with the special emphasis on 4-node quadrilateral elements. The NC modes have been used as a key scheme to improve the behaviors of various types of new finite elements, i.e., Mindlin plate bending elements, membrane elements with drilling degrees of freedom, flat shell elements. The NC modes are classified into three groups according to the 'correction constants' of 'Direct Modification Method'. The first group is 'basic NC modes', which have been widely used by a number of researchers in the finite element communities. The basic NC modes are effective to improve the behaviors of regular shaped elements. The second group is 'hierarchical NC modes' which improve the behaviors of distorted elements effectively. The last group is 'higher order NC modes' which improve the behaviors of plate-bending elements. When the basic NC modes are combined with hierarchical or higher order NC modes, the elements become insensitive to mesh distortions. When the membrane component of a flat shell has 'hierarchical NC modes', the membrane locking can be suppressed. A number of numerical tests are carried out to show the positive effect of aforementioned various NC modes incorporated into various types of finite elements.

• Journal of the Korean Society for Precision Engineering
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• v.20 no.9
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• pp.13-19
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• 2003

• Journal of the Korean Society for Precision Engineering
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• v.17 no.5
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• pp.41-50
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• 2000

NC(Numerical Control)는 1949년 미 공군이 Parson (Fig. 1 (a))이라는 사람에게 프로펠러 (Propeller)용 블레이드(Blade)의 윤곽을 검사하기 위한 판 게이지(Gauge)(Fig. 1 b)) 개발을 의뢰한 것이 계기가 되어 발명되었다. 이후, 신시나티 미라크론(Cincinati Miracle)이라는 공작기계 업체가 NC 사업에 참여하게 되고, 1952년 최초로 MIT(Massachusetts Institute of Technology)의 서보기구연구소(Servo-mechanism laboratory)에 의해 NC 공작기계가 탄생(Fig. 1 (c)) 되었다.(중략)

• International Journal of CAD/CAM
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• v.4 no.1
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• pp.47-53
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• 2004

The subdivision surface is the limit of recursively refined polyhedral mesh. It is quite intuitive that the multi-resolution feature can be utilized to simplify generation of NC (Numerical Control) tool paths for rough machining. In this paper, a new method of parallel NC tool path generation for subdivision surfaces is presented. The basic idea of the method includes two steps: first, extending G-Buffer to a strip buffer (called S-Buffer) by dividing the working area into strips to generate NC tool paths for objects of large size; second, generating NC tool paths by parallel implementation of S-Buffer based on MPI (Message Passing Interface). Moreover, the recursion depth of the surface can be estimated for a user-specified error tolerance, so we substitute the polyhedral mesh for the limit surface during rough machining. Furthermore, we exploit the locality of S-Buffer and develop a dynamic division and load-balanced strategy to effectively parallelize S-Buffer.

• Journal of the Korean Society for Precision Engineering
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• v.19 no.7
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• pp.171-179
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• 2002

STEP-NC is the next generation CNC controller taking STEP-based data model as the interface scheme (or language) between CAM and CNC, and carrying out various intelligent functions. At the moment, efforts are being made worldwide to establish international standard for the new interface scheme formalized as ISO14649. As the new language is being established, increasing attention is being paid to the development of the new CNC. Korea STEP-NC is an integrated STEP-NC system taking ISO 14649 as an input, and carrying out various intelligent functions. It is composed of 5 modules: 1) Shop Floor Programming System (PosSFP), 2) Tool Path Generator (PosTPG), 3) Tool Path Viewer (PosTPV), 4) Man Machine Interface (PosMMI), and 5) CNC Kernel (PosCNC). Distinguished from other prototypes (of Europe and USA), the Korea STEP-NC is top-down designed, and bottom-up implemented comprehensively incorporating all the crucial components for realizing the full benefit of STEP-NC paradigm, without using any existing commercial CAD/CAM systems and CNC kernels. The Korea STEP-NC prototype was successfully demonstrated and evaluated in the ISO conventions Together with prototypes of Europe and USA, Korea STEP-NC will be used as a reference system fur the Triangular Conformance Test to be jointly carried out by ISO TC184 SC1, SC4, and IMS Project.

• 제어로봇시스템학회:학술대회논문집
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• 1990.10a
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• pp.167-169
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• 1990

This paper describes the DNC technology as a partial approach to a achieving dr system integration of NC machines. The study deals with development of a system to unify NC machines by utilizing a DNC. The system is provided to have the potential of offering ft environment and application fundamentals to construct factory automation.