• 한국정보통신학회논문지
• /
• 제12권3호
• /
• pp.575-580
• /
• 2008

최근 IPv4 주소의 고갈과 더블어 P2P 트래픽의 증가로 인해 NAT의 사용은 피할 수 없다. NAT 내부에 있는 서버는 외부의 릴레이 서버를 통해서만 접속이 이루어지는 속성을 가지고 있다. 따라서 NAT 외부에 있는 서버는 많은 자원을 소비하고 네트워크 트래픽을 증가시킨다. 본 논문에서는 NAT 외부에서 NAT 내부로의 세션을 형성 할 수 있고, NAT 외부의 릴레이 서버를 NAT 내부에 둠으로써 네트워크 트래픽을 감소시킬 수 있는 토폴로지를 제안한다.

• Biomolecules & Therapeutics
• /
• 제10권3호
• /
• pp.193-199
• /
• 2002

The arylamine N-acetyltransferases (NATs) are a family of enzymes that N-acetylate mylhydrazines and arylamines through transfer of an acetyl group from acetyl coenzyme A. This activity was found to vary among individuals as a Mendalian trait and the basis of the genetic differences in human NAT activity is one of the best of the genetic studied examples of pharmacogenetic variation. The classical N-acetylation polymorphism is regulated at the NAT2 locus, which segregates individuals into rapid, intermediate, and slow acetylator phenotypes. In this study, the relationship between NAT2 activity phenotype using HPLC:UV assay for the determination of dapsone and monoacetyldapsone in plasma and NAT2 genotype by PCR-RFLP (polymerase chain reaction-restriction fragment length polymorphism) was investigated in the F2 hybrid (Fischer 344 vs Wistar-Kyoto) rats. Three Common mutant alleles at the NAT2 gene locus have been identified in the F2 generation progeny of Fischer 344 rats as raid acetylator and Wistar-Kyoto rats as slow acetylator segregated into three modes (low, intermediates, and high) with simple Mendelian inheritance. The metabolic activity of NAT2 of the intermediate and rapid acetylators is significant1y greater than slow acetylator, but the metabolic activity of rapid acetylator is not significantly different from Intermediate type. Therefore, we could observe that complete trimodal NAT2 genotypic alleles and incomplete trimodal NAT2 metabolic phenotypic distribution in tile F2 hybrid rats. These observations suggest that the relationships between NAT2 genotype and metabolic phenotype exists and F2 hybrid (Fischer 344: Wistar-Kyoto) animal models about NAT2 polymorphism might be applied in the toxicity and pharmacogenetic studies of arylamine drugs and carcinogens.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권21호
• /
• pp.9203-9210
• /
• 2014

Purpose: To explore associations of CYP2E1 and NAT2 polymorphisms with lung cancer susceptibility among Mongolian and Han populations in the Inner Mongolian region. Materials and Methods: CYP2E1 and NAT2 polymorphisms were detected by PCR-RFLP in 930 lung cancer patients and 1000 controls. Results: (1) Disequilibrium of the distribution of NAT2 polymorphism was found in lung cancer patients among Han and Mongolian populations (p=0.031). (2) Lung cancer risk was higher in individuals with c1, D allele of CYP2E1 RsaI/PstI, DraI polymorphisms and slow acetylation of NAT2 (c1 compared with c2, OR=1.382, 95%CI: 1.178-1.587, p=0.003; D compared with C, OR=1.241, 95%CI: 1.053-1.419, P<0.001; slow acetylation compared with rapid acetylation, OR=1.359, 95%CI:1.042-1.768, p=0.056) (3) Compared with c2/c2 and rapid acetylation, c1/c1 together with slow acetylation synergetically increased risk of lung cancer 2.83 fold. (4) Smokers with CYP2E1 c1/c1, DD, and NAT2 slow acetylation have 2.365, 1.916, 1.841 fold lung cancer risk than others with c2/c2, CC and NAT2 rapid acetylation, respectively. (5) Han smokers with NAT2 slow acetylation have 1.974 fold lung cancer risk than others with rapid acetylation. Conclusions: Disequilibrium distribution of NAT2 polymorphism was found in lung cancer patients among Han and Mongolian populations. Besides, Han smokers with NAT2 slow acetylation may have higher lung cancer risk compared with rapid acetylation couterparts. CYP2E1 c1/c1, DD and NAT2 slow acetylation, especially combined with smoking, contributes to the development of lung cancer. CYP2E1 c1/c1 or DD genotype and NAT2 slow acetylation have strong synergistic action in increasing lung cancer risk.

• 한국재료학회:학술대회논문집
• /
• 한국재료학회 2007년도 추계학술발표대회 및
• /
• pp.113.2-113.2
• /
• 2007

• 한국재료학회:학술대회논문집
• /
• 한국재료학회 1998년도 IUMRS-ICEM ABSTRACT BOOK
• /
• pp.42.2-42
• /
• 1998

• 한국자기학회:학술대회 개요집
• /
• 한국자기학회 2008년도 Asian Magnetics Conference
• /
• pp.245.2-245.2
• /
• 2008

• 대한핵의학회:학술대회논문집
• /
• 대한핵의학회 2004년도 추계학술대회 및 총회
• /
• pp.404.2-404.2
• /
• 2004

• 제어로봇시스템학회:학술대회논문집
• /
• 제어로봇시스템학회 2002년도 ICCAS
• /
• pp.53.1-53
• /
• 2002

$\textbullet$ Contents 1. Introduction $\textbullet$ Contents 2. Error Models of Navigation $\textbullet$ Contents 3. Observablity Properties of GPS/INS $\textbullet$ Contents 4. Measurement System for INS Error Estimation $\textbullet$ Contents 5. Numerical Simulation Results $\textbullet$ Contents 6. Conclusions

• 한국동물학회:학술대회논문집
• /
• 한국동물학회 1998년도 한국생물과학협회 학술발표대회
• /
• pp.325.2-325
• /
• 1998

No Abstract, See Full Text

• 제어로봇시스템학회:학술대회논문집
• /
• 제어로봇시스템학회 2002년도 ICCAS
• /
• pp.34.4-34
• /
• 2002

1. Introduction 2. Basic Camera models and geometry 3. Projection of line widths 4. Camera calibration algorithm 5. Experimental results 6. Conclusions and future work