• Journal of Korean Society for Atmospheric Environment
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• v.24 no.4
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• pp.423-438
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• 2008

BEIS2 (Biogenic Emissions Inventory System version 2) and BEIS3.12 (BEIS version 3.12) were used to estimate hourly biogenic emissions over South Korea using a set of vegetation and meteorological data simulated with the MM5 (Mesoscale Model version 5). Two biogenic emission models utilized different emission factors and showed different responses to solar radiations, resulting in about $10{\sim}20%$ difference in the nationwide isoprene emission estimates. Among the 11-vegetation classes, it was found that mixed forest and deciduous forest are the most important vegetation classes producing isoprene emissions over South Korea comprising ${\sim}90%$ of the total. The simulated isoprene concentrations over Seoul metropolitan area show that diurnal and daily variations match relatively well with the PAMS (Photochemical Air Monitoring Station) measurements during the period of June 3${\sim}$June 10, 2004. Compared to BEIS2, BEIS3.12 yielded ${\sim}35%$ higher isoprene concentrations during daytime and presented better matches to the high peaks observed over the Seoul area. This study showed that the importance of vegetation data and emission factors to estimate biogenic emissions. Thus, it is expected to improve domestic vegetation categories and emission factors in order to better represent biogenic emissions over South Korea.

• The Korean Nurse
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• v.35 no.1
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• pp.66-80
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• 1996

Reacently one the main issues has been to develop useful strategies to improve hospital services for patients in the health care delivery system in our rapidly changing society. This study has focused on exploring the perceptions that the clinical nurses have concerning who they are and what they are going to become in the days ahead as medical care reaches a new stage of advancement centered around the patient and hospital services. This study in also based upon the premise that the role of the clinical nurse practitioner. is central to the progress of any patient centered nursing program. This study was carried out by the members of the academic committee of Seoul Branch of Korean Nurses Association from January 1995 to February 1995. The interview method was a semi-structured questionnaire used to collect data from 25 staff nurses who were working more than 3 years at 3 different university hospitals in Seoul. The 6 interviews were selected from each hospital and they were trained for the interviewing techniques. The data were analysed qualitatively and 10 elements of the nurse's responsibilities classified such as caring for the patients (which includes specific medical care as well as general); assessing; diagnosing; coordinating with other health personnel; careful listening; teaching and the patient guiding; administering the prescriptions; giving information and counseling the patient; ward management. Although the premise of this study was based on a wholistic concept, the overall behavioral aspects of hospital clinical nursing were the major thrust of the questionnaire. Broad philosophical questions regarding the nature of nursing need to be further explored. The data gathered for this questionnaire should be useful as a reenforcement tool in educating nursing students as well as in continuing education for clinical nurses. For the future, another study should be done to determine the nursing/patient relationship.

• The Journal of the Korea Contents Association
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• v.9 no.11
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• pp.391-398
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• 2009

The purpose of this study was to investigate the effects of aerobic exercise(folk dance) with resistance exercise(elastic band) for 12 weeks on blood MDA concentration and SOD GPx activities in the elderly women. The subjects consisted 12 elderly women between 65-75 years exercise were folk dance(HRmax 50-60% levels, 60min, two per a week) and elastic band(yellow band, 60min, two per a week) program for 12 weeks. SOD, GPx activities in the before combined exercise were significantly increased than that in after combined exercise. These results show that aerobic exercise with resistance exercise program in considered to contribute enforced of antioxidant enzyme system by increased SOD and GPx activities in elderly women.

• Bulletin of the Korean Chemical Society
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• v.32 no.9
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• pp.3327-3332
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• 2011

Antimicrobial peptides have recently gained the much attention because of their ability to make defense system from attacking bacterial infections. Drosocin has been considered as very attractive antibiotic agents because of low toxicity against human erythrocytes and active at the low concentration. We have studied the structureactivity relationship of a glycopeptide drosocin focused on the N-acetyl-D-galactoside at $Thr^{11}$ residue. Based on the radial diffusion assay, we found that the acetylation of carbohydrate moiety increased the antimicrobial activity and the $Pro^{10}$, present in the middle of drosocin plays an important role in the antimicrobial activity. Our results provide a good lead compound for further studies on the design of drosocin-based analogues targeting glyco linked Thr site.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• v.29 no.1
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• pp.319-324
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• 2005

This study was carried out for the purpose of proposing the guideline for the non-mischief and comfortable coastal leisure activities to reduce the marine pollution caused by sea fishing and strengthen the marine management and supervision for the fishing activity. In research method, a extensive reference was examined and analyzed, and the questionnaire investigation and field work were carried out to recognize the present conditions and problems concerning the environmental pollution caused by sea fishing. At the same time, the guideline for the safe and comfortable activities was proposed by diagnosing of actual evil conditions of marine environment due to the sea fishing activity and by analyzing of foreign mangement cases. On the basis of these research results, it is useful to contrive a management criteria for the realities investigation on the pollution of coastal activities. It also contributes to develop the regional economy by controlling coastal leisure activities effectively and systematically through the national publicity for the prevention of marine pollution.

• Korean Journal of Pharmacognosy
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• v.39 no.3
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• pp.165-173
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• 2008

Aldose reductase (AR), the principal enzyme of the polyol pathway, has been shown to play an important role in the diabetic complications, including diabetic cataract. The inhibitors of AR, therefore, would be potential agents for prevention of diabetic complications. As part of our ongoing project directed toward the discovery of preventive and/or treatment for diabetic complications, 48 Korean herbal medicines have been investigated with an in vitro evaluation system using aldose reductase inhibitory activities. Of these, 12 herbal medicines exhibited a significant inhibitory activity against aldose reductase. Particularly, seven herbal medicines, i.e., Eurya japonica, Chrysanthemum indicum, Akebia quinata, Saururus chinensis, Catalpa bignonioides, Lonicera japonica, Vitex rotundifolia showed two times more potent inhibitory activity than the positive control 3.3-tetramethyleneglutaric acid (TMG). In addition, Catalpa bignonioides showed the retardation of cataract-opacification of the lens of the eye under diabetic condition by xylose. Therefore, this result may provide a potential therapeutic approach for preventing and treating diabetic cataracts.

• Bulletin of the Korean Chemical Society
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• v.32 no.7
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• pp.2351-2357
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• 2011

Three new metal-organic copper(II) complexes, $[Cu(H_2PZTC)_2]_n{\cdot}2nH_2O$ (1), $[Cu(HPZTC){\cdot}2H_2O]_n{\cdot}2nH_2O$ (2), and $Cu_2[(PZHD)(OH)(H_2O)_2]_n$ (3) ($H_3PZTC$ = pyrazine-2,3,5-tricarboxylic acid, $PZHD^{3-}$ = 2-hydroxypyrazine-3,5-dicarboxylate), have been synthesized from $Cu(II)/H_3PZTC$ system under different synthetic conditions, and characterized by single-crystal X-ray diffraction, elemental analysis, IR spectroscopy and thermogravimetric analysis. In complexes 1 and 2, $H_3PZTC$ ligands loose one and two protons, which were transformed into $H_2PZTC^-$ anion and $HPZTC^{2-}$ dianion under different preparation condition, respectively. Furthermore, two ligands coordinate with Cu(II) cations in different modes, leading to the formation of the different chain structures. In complex 3, $H_3PZTC$ ligand was converted into a new ligand-PZHD by in situ decarboxylation and hydroxylation under a higher pH value than that for complexes 1 and 2. PZHD ligands link the Cu(II) cations to form a 2D layer structure. These results demonstrate that the preparation conditions, including pH value and reaction temperature etc, play an important role in the construction of complexes based on $H_3PZTC$ ligand.

• The Journal of Korean Physical Therapy
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• v.21 no.3
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• pp.53-59
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• 2009

Purpose: The purpose of this study was to investigate the effects of proprioceptive exercise on the body alignment of elderly women. Method: The experimental group consisted of twenty elderly women who participated in proprioceptive exercise for 8 weeks. The subjects were measured using Global Posture System equipment for assessing their body alignment. Body alignment was measured at the ear, shoulder joint, knee joint and calcaneocuboid joint on the sagittal plane, and the left and right acromion process positions, the ASIS and the medial malleoulus on the coronal plane. The body alignment data was used to assess the changes before and after proprioceptive exercise. The data of the experimental group was compared and analyzed using the Wilcoxon singed-rank test between before and after proprioceptive exercise. The Mann-Whithney test was used to compare the experimental group and the control group. Result: The result of this study was that the body alignment of the experimental group at the ear and knee joint on the sagittal plane was significantly in alignment with the line of gravity (p<0.05) before and after proprioceptive exercise. The body alignment was statistically different (p<0.05) between the experimental group and the control group on the frontal plane and sagittal plane. Conclusion: This study showed that proprioceptive exercise does affect the body alignment in elderly women. This indicates that there is interaction that plays a crucial role for proprioceptive stimuli and the body alignment.

• Journal of Environmental Policy
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• v.10 no.1
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• pp.93-127
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• 2011

Investment on technology to obtain green energy is prevailing all over the world. The technology development project is more likely to involve multiple sub-projects, each of which is related to develop elementary technology when the project is larger and nation-wide. However, the methodologies identifying optimal combination of elementary technologies among the candidates have been very few. Hence, the purpose of this paper is to propose a novel methodology which provides an optimal combination of green energy technologies. To do so, to-be developed technologies are clustered with multiple categories. Among the technologies, based on Delphi method, the experts select a representative technology, which is indispensible to the green energy system and has the highest connectivity with other elementary technologies. Then the methodology selects an elementary technology from each technology category based on two metrics: Relatedness with representative technology and project risk. To show the feasibility of the proposed methodology, we applied the methodology to an actual windmill development project.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.14
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• pp.5755-5762
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• 2015

Background: Short-course preoperative radiation (SCRT) with delayed surgery was found to increase pathologic complete response (pCR) rates in several trials. However, there was no clear answer on whether SCRT or long-course chemo-radiotherapy (LCRT) is more effective. Therefore we conducted this meta-analysis to evaluate the safety and efficacy of SCRT versus LCRT, both with delayed surgery, for treatment of rectal cancer. Materials and Methods: The literature was searched from PubMed, EMBASE, Web of Science, Cochrane Library and clinicaltrials.gov up to November, 2014. Quality of the randomized controlled trials (RCTs) was evaluated according to the Cochrane's risk of bias tool of RCT. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) system was used to rate the level of evidence. Review Manager 5.3 was employed for statistical analysis. Pooled risk ratios (RRs) and 95% confidence intervals (CIs) were calculated. Results: Three RCTs, with a total of 357 rectal cancer patients, were included in this systematic review. Metaanalysis results demonstrated there were no significantly differences in sphincter preservation rate, local recurrence rate, grade 3~4 acute toxicity, R0 resection rate and downstaging rate. Compared with SCRT, LCRT was associated with significant increase in the pCR rate [RR=0.49, 95%CI (0.31, 0.78), P=0.003]. Conclusions: In terms of sphincter preservation rate, local recurrence rate, grade 3~4 acute toxicity, R0 resection rate and downstaging rate, SCRT with delayed surgery is as effective as LCRT with delayed surgery for management of rectal cancer. LCRT significantly increased pCR rate compared with SCRT. Due to risk of bias and imprecision, further multi-center large sample RCTs were needed to confirm this conclusion.