• Title/Summary/Keyword: N-fixation

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Tomographic and histometric analysis of autogenous bone block and synthetic hydroxyapatite block grafts without rigid fixation on rabbit calvaria

  • Bae, Soo-Yong;Park, Jung-Chul;Shin, Hyun-Seung;Lee, Yong-Keun;Choi, Seong-Ho;Jung, Ui-Won
    • Journal of Periodontal and Implant Science
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    • v.44 no.5
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    • pp.251-258
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    • 2014
  • Purpose: The preferred material for bone augmentation beyond the envelope of skeletal bone is the bone block graft, due to its dimensional stability. We evaluated the necessity of rigid fixation for the bone block graft, and compared the bone regeneration and volume maintenance associated with grafting using a synthetic hydroxyapatite block (HAB) and an autogenous bone block (ABB) without rigid fixation on rabbit calvaria over two different periods. Methods: Cylinder-shaped synthetic HAB and ABB were positioned without fixation on the rabbit calvarium (n=16). The animals were sacrificed at 4 or 8 weeks postoperatively, and the grafted materials were analyzed at each healing period using microcomputed tomography and histologic evaluation. Results: Integration of the graft and the recipient bed was observed in all specimens, although minor dislocation of the graft materials from the original position was evident in some specimens (six ABB and ten HAB samples). A tendency toward progressive bone resorption was observed in the grafted ABB but not in the grafted HAB, which maintained an intact appearance. In the HAB group, the area of new bone increased between 4 and 8 weeks postoperatively, but the difference was not statistically significant. Conclusions: The nonfixed HAB was successfully integrated into the recipient bed after both healing periods in the rabbit calvaria. In spite of limited bone formation activity in comparison to ABB, HAB may be a favorable substitute osteoconductive bone material.

Local ridge augmentation using a composite of bone substitute and collagen membrane at peri-implant dehiscence defects: a clinical, radiographic and histological analyses. (성견에서 차단막/골이식재 복합체를 이용한 임플란트 주위 골유도재생 효과: 임상적, 방사선학적, 조직학적 평가)

  • Song, Young Woo;Yoon, So-Ra;Cha, Jae-Kook;Lee, Jung-Seok;Choi, Seong-Ho;Jung, Ui-Won
    • The Journal of the Korean dental association
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    • v.55 no.10
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    • pp.676-687
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    • 2017
  • Objectives : The aim of this study was to evaluate the effects of a composite of bone substitute and collagen barrier membrane (bone patch) for local ridge augmentation at peri-implant dehiscence defects on the clinical efficacy and positional stability in dogs. Materials and methods : Implant placement and ridge augmentation procedure were performed at surgically created peri-implant dehiscence defects in canine mandible (n=6). Four treatment modalities were randomly applied: i) bone patch group, ii) Guided bone regeneration (GBR) without pin fixation group (bone graft and collagen membrane), iii) GBR with pin fixation group, and iv) negative control group. After 12 weeks, clinical, micro-CT and histological analyses were performed. Results : Histologic analysis showed that bone patch group had similar results to GBR group and GBR with fixation group in terms of new bone formation. Micro-CT analysis revealed similar results to histologic analysis in terms of total volume maintenance. Operating time was shorter in bone patch group compared to GBR group and GBR with fixation groups. Conclusions : GBR using bone patch could simplify the ridge augmentation procedure with reduced operating time and equivalent biological performance compared to the conventional procedure.

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Controlled active exercise after open reduction and internal fixation of hand fractures

  • Jun, Dongkeun;Bae, Jaehyun;Shin, Donghyeok;Choi, Hyungon;Kim, Jeenam;Lee, Myungchul
    • Archives of Plastic Surgery
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    • v.48 no.1
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    • pp.98-106
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    • 2021
  • Background Hand fractures can be treated using various operative or nonoperative methods. When an operative technique utilizing fixation is performed, early postoperative mobilization has been advocated. We implemented a protocol involving controlled active exercise in the early postoperative period and analyzed the outcomes. Methods Patients who were diagnosed with proximal phalangeal or metacarpal fractures of the second to fifth digits were included (n=37). Minimally invasive open reduction and internal fixation procedures were performed. At 3 weeks postoperatively, controlled active exercise was initiated, with stress applied against the direction of axial loading. The exercise involved pain-free active traction in three positions (supination, neutral, and pronation) between 3 and 5 weeks postoperatively. Postoperative radiographs and range of motion (ROM) in the interphalangeal and metacarpophalangeal joints were analyzed. Results Significant improvements in ROM were found between 6 and 12 weeks for both proximal phalangeal and metacarpal fractures (P<0.05). At 12 weeks, 26 patients achieved a total ROM of more than 230° in the affected finger. Postoperative radiographic images demonstrated union of the affected proximal phalangeal and metacarpal bones at a 20-week postoperative follow-up. Conclusions Minimally invasive open reduction and internal fixation minimized periosteal and peritendinous dissection in hand fractures. Controlled active exercise utilizing pain-free active traction in three different positions resulted in early functional exercise with an acceptable ROM.

Enhancement and Evaluation of Fatigue Resistance for Spine Fixation System (척추고정장치의 피로성능 평가와 향상)

  • Kim, Hyun-Mook;Kim, Sung-Kon
    • Journal of the Korean Society for Precision Engineering
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    • v.26 no.8
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    • pp.142-147
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    • 2009
  • Spinal fixation systems provide surgical versatility, but the complexity of their design reduces their strength and fatigue resistance. There is no published data on the mechanical properties of such screws. Screws were assembled according to a vertebrectomy model for destructive mechanical testing. A group of two assemblies was tested in static compression. One group was applied to surface a grit blasting method and another group was applied to surface a bead blasting method. Modes of failure, yield, and ultimate strength, yield stiffness, and cycles to failure were determined for six assembles. Static compression 2% offset yield load ranges was from 327 to 419N. Fatigue loads were determined two levels, 37.5% and 50% of the average load from static compression ultimate load. An assembly of bead blasting treatment only achieved 5 million cycles at 37.5% level in compression bending.

Study on Evaluation Method of Driver's Cognitive Workload with using In-Vehicle Information Systems (차량정보기기 사용에서 운전자의 인지부담 평가방법에 관한 연구)

  • Jeon, Yong-Wook
    • Journal of the Ergonomics Society of Korea
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    • v.29 no.5
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    • pp.735-739
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    • 2010
  • Driving workload is increasing according to developing new in-vehicle devices and introducing driving information systems. In this research using a driving simulator, EFRP (Eye Fixation Related Potential) was measured for evaluating driving attention and distraction while tasking cognitive workload, n-back tasks. The result of EFRP was compared with driver behaviors. Results suggest that EFRP is able to use for a method of evaluating driving workload, however, the analysis of driver behavior is difficult to find driving attention and distraction in the case of free flow of traffic situation.

Nitrogen Fixation and In Situ Dry Matter and Fibre Constituents Disappearance of Wheat Straw Treated with Urea and Boric Acid in Murrah Buffaloes

  • Dass, R.S.;Mehra, U.R.;Verma, A.K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.13 no.8
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    • pp.1133-1136
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    • 2000
  • Wheat straw was treated with 4 per cent urea at a moisture level of 50 per cent alongwith different levels of boric acid viz. 1, 2, 3 and 4 per cent, under laboratory conditions to know the impact of boric acid on ammonia-N fixation in the straw. Murrah buffaloes were used for determining the disappearance of dry matter, CP and fibre constituents by nylon bag technique. Ammoniation increased CP content of wheat straw, which increased further due to addition of boric acid. Low level of boric acid (1%) had no adverse effect on fibre constituents disappearance but at higher levels there was a depressioon in the disappearance of fibre coonstituents. It can be concluded that low level of boric acid was sufficient to trap the excess ammonia released during urea ammoniation of wheat straw without affecting other constituents and their disappearance in the rumen of buffaloes.

ATOM technique: Anatomic reduction using screw-wire Traction for Open reduction and internal fixation of Mandibular fractures

  • Ingole, Pranav D.;Rajguru, Jignesh G.;Budhraja, Nilima J.;Shenoi, Ramakrishna S.;Karmarkar, Jui S.;Dahake, Rahul N.
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.48 no.2
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    • pp.122-124
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    • 2022
  • Various techniques are well documented to obtain anatomic reduction, such as reduction forceps, manual reduction, or a combination of these methods. However, these techniques have inherent drawbacks. We propose a new intra-operative technique for anatomic reduction using screw-wire traction for open reduction and internal fixation of mandibular fractures.

Changes of Amino Acid Content of Cultured Tobacco Cells by Association Culture with Nostoc muscorum (Nostoc muscorum과 혼합배양한 담배 배양세포의 아미노산 함량 변화)

  • 정현숙
    • Journal of Plant Biology
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    • v.34 no.1
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    • pp.31-35
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    • 1991
  • Induction of symbiosis between N. muscorum and cultured tobacco cells associately cultured on nitrogen-free medium and effects of polyamines on culture condition were carried out. Analysis of amino acid composition in associate cultures showed increase in total amino acid amounts than single culture of cultured tobacco cells and methionine was markly increased in associative culture on N-free medium treated with 1 mM spermine. These results indicated that the composition of amino acids increased effectively in associative cultures by nitrogen fixation of N. muscorum.scorum.

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Study on Effective Preservation of Bovine Pericardium Using Decellulariation and ${\alpha}$-galactosidase for Eliminating Xenoreactive Antigen (이종 항원 제거를 위한 무세포화와 알파-갈락토시다아제를 이용한 효과적인 우심낭 보존 방법에 관한 연구)

  • Kim, Min-Seok;Park, Cham-Jin;Kim, Soo-Hwan;Lim, Hong-Gook;Kim, Yong-Jin
    • Journal of Chest Surgery
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    • v.43 no.6
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    • pp.576-587
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    • 2010
  • Background: Effective decellularization and fixation process is critical, in order to use xenogenic valves clinically. In the present study, we decellularized bovine pericardium using sodium dodecyl sulfate (SDS) and N-lauroyl sarcosinate, treated with $\alpha$-galactosidase, and then fixed in various manners, to find out the most effective tissue preservation & fixation procedure. Material and Method: Bovine pericardium was decellularized with SDS and N-lauroyl sarcosinate, and treated with $\alpha$-galactosidase. Both groups were fixed differently, by varying glutaraldehyde (GA) or EDC (1-ethyl-3-(3-dimethyl aminopropyl)-carbodiimide)/N-hydroxysuccinamide (NHS) treatment conditions. Thereafter, physical examination, tensile strength test, thermal stability test, cytotoxicity test, pronase test, pronase-ninhydrin test, purpald test, permeability test, compliance test, H&E staining, DNA quantification, and $\alpha$-galactose staining were carried out to each groups. Result: GA fixed groups showed better physical properties and thermal stability than EDC/NHS fixed groups, EDC/NHS-GA dual fixed groups showed better physical properties and thermal stability than EDC/NHS fixed groups, and showed better thermal stability than GA fixed groups. In pronase test and pronase-ninhydrin test, GA fixed groups and EDC/NHS-GA dual fixed groups showed stronger crosslinks than EDC/NHS groups. Permeability and compliance tended to increase in EDC/NHS-GA dual fixed groups, compared to GA fixed groups. But, EDC/NHS-GA dual fixed groups had stronger tensile strength and lower cytotoxicity than GA fixed groups. Conclusion: We have verified that EDC/NHS-GA dual fixation can make effective crosslinks and lower the toxicity of GA fixation. Henceforth, we will verify if EDC/NHS-GA dual fixation can lower calcifications & tissue failure in vivo experiment.

Hardness and Dimensional Stability of Radiata Pine (Pinus radiata D.Don) Heat-Compressed Wood - Effect of Press Temperature & Time - (라디에타소나무 열압밀화 목재의 경도와 치수안정성 - 압체 온도와 시간의 영향 -)

  • Hwang, Sung-Wook;Lee, Won-Hee
    • Journal of the Korean Wood Science and Technology
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    • v.39 no.3
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    • pp.206-212
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    • 2011
  • It was investigated the hardness and dimensional stability of heat-compressed wood by compression temperature and time. The surface hardness of heat-compressed wood increased with increasing compression temperature. The lowest hardness value (5.0 N/$mm^2$) was observed in the temperature $70^{\circ}C$ while the highest value (15.6 N/$mm^2$) was obtained in compression temperature $220^{\circ}C$. Dimensional recovery test results showed that fixation of compression set improved with increasing compression temperature. However, the fixation effects were negligible by press time. Contact angle increased with increasing press temperature and time.