• Title/Summary/Keyword: N:P ratio

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Overall and disease-specific survival outcomes following primary surgery for oral squamous cell carcinoma: analysis of consecutive 67 patients

  • Sim, Yookyeong Carolyn;Hwang, Jong-Hyun;Ahn, Kang-Min
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.45 no.2
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    • pp.83-90
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    • 2019
  • Objectives: This study evaluated the predictive factors for survival of patients with oral squamous cell carcinoma (OSCC) and investigated the overall and disease-specific survival (DSS) outcomes. Materials and Methods: A total of 67 consecutive patients who underwent surgery for OSCC from January 2006 to November 2014 were included in this study. Patients were classified according to age, sex, pTNM stages, primary sites, smoking and alcohol drinking habits, depth of invasion, perineural and lymphovascular invasion, cell differentiation and postoperative radiotherapy. Kaplan-Meier methods were used to estimate the survival categorized by patient groups. Cox regression methods were used to investigate the main independent predictors of survival. Results: Nineteen patients died of OSCC during follow-up periods. Another five patients died of other diseases including lung adenocarcinoma (n=1), cerebral infarction (n=1), general weakness (n=2), and pneumonia (n=1). The tongue (n=16) was the most common site for primary origin, followed by buccal mucosa (n=15), mandibular gingiva (n=15), maxillary gingiva (n=9), floor of mouth (n=9), retromolar trigone (n=2), and palate (n=1). Eleven patients had pTNM stage I disease, followed by stage II (n=22) and stage IV (n=34). No patients had pTNM stage III disease in this study. The overall survival of all patients was 64.2% and the DSS was 71.6%. DSS of patients with stage I and II disease was 100%. Stepwise Cox regression showed the two predictors for DSS were pTNM stage (P<0.0001, odds ratio=19.633) and presence of metastatic lymph nodes (P=0.0004, odds ratio=0.1039). Conclusion: OSCC has been associated with poor prognosis; however, there were improved survival outcomes compared with past studies. Advanced-stage disease and presence of metastatic lymph nodes were associated with poorer survival compared with early-stage OSCC and absence of neck node metastasis. Stage I and II OSCC were associated with excellent survival results in this study.

The evaluation of useful on the additional PET/CT Liver scan (PET/CT 검사에서 Gastrointestinal Cancer 환자의 Liver 추가촬영에 대한 유용성 평가)

  • Park, Se Youn;Lee, Hwa Jin;Lee, Mu Seok;Kim, Jung Uk;Ji, Hye In
    • The Korean Journal of Nuclear Medicine Technology
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    • v.20 no.2
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    • pp.46-48
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    • 2016
  • Purpose The liver one of the most common site for distant metastasis for a variety of tumor, especially of gastrointestinal origin. the purpose of this study was to analyze image quality between standard scan and additional liver scan. Materials and Methods From September 2015 to February 2016. 152 patients were examined undergo gastrointestinal cancer. 32 patients confirmed liver metastasis analyzed same liver ROI level and check the SNR, SUV and T/N ratio Results The $SNR_{mean}$ of standard was $17.7{\pm}10.3$; addition was $22.3{\pm}9.7$ (p<0.05). In $SUV_{max}$ of standard was $6.7{\pm}2.8$; addition was $7.6{\pm}3.2$ (P<0.05). and the T/N ratio of standard was $2.1{\pm}0.6$; addition was $2.5{\pm}0.8$ (P<0.05). Conclusion The $SNR_{mean}$, $SUV_{max}$ and T/N ratio were higher than those on the first scan (P<0.05). The SNRmean showed the highest change rate among the parameters. A additional liver scan is more favorable for the detection of gastrointestinal cancer patients.

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The Effect of Dietary Phytase on Nitrogen and Phosphorus Excretion of Gestating and Lactating Sows (Phytase 첨가가 임신돈과 포유돈의 분뇨 배설량 및 질소와 인 배설량에 미치는 영향)

  • HwangBo, Jong;Hong, Eui-Chul
    • Journal of Animal Science and Technology
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    • v.54 no.4
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    • pp.291-297
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    • 2012
  • This study was carried out to investigate the effect of dietary phytase on nitrogen and phosphorus excretion of gestating and lactating sows (Yorkshire ${\times}$ Landrace ${\times}$ Duroc). Twelve gestating sows and twelve lactating sows were used in this study and were divided into 2 groups (1 control group and 1 treatment group, 6 replications/group) the control group was without phytase and the treatment group was fed with phytase (750 FTU/kg) in the diet, respectively. Body weights of gestating and lactating sows were $208.9{\pm}13.8$ kg and $190.5{\pm}22.9$ kg, respectively. In gestating sows, feed intake was greater in phytase fed group than the control (P<0.05), but water intake and total excretion were not different between the groups. In lactating sows, feed and water intakes and total excretion were not different between the groups. The N intake of lactating sows was higher in phytase fed group than control (P<0.05) but N excretion ratio was not different. In lactating sows, N intake and excretion and N excretion ratio were not significantly different between the groups. P excretion and excretion ratio in gestating sows decreased by phytase treatment (P<0.05) as compared to control. In lactating sows, N intake and excretion was not significantly different by added phytase (P>0.05). Finally, dietary addition of phytase decreased P excretion in feces of gestating and lactating sows.

Clinical Significance of the Aortic Node in Non-small Cell Lung Cancer of the Left Upper Lobe (좌상엽에 발생한 비소세포형 폐암에서 Aortic Node의 의의)

  • 김대준;김길동;이기종;정경영
    • Journal of Chest Surgery
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    • v.36 no.11
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    • pp.846-851
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    • 2003
  • Background: To clarify the clinical significance of the aortic nodes in resected non-small cell lung cancer of the left upper lobe. Material and Method: One hundred fifty six patients with resected non-small cell lung cancer of the left upper lobe were studied. Patients who received preoperative induction therapy, non-curative operation or defined as operative mortality were excluded from this study. Result: In N2 left upper lobe tumors, aortic nodes comprised 52.7% of the metastatic mediastinal lymph nodes. In single station N2 disease, a frequently metastasized station was aortic node (64.3%). 5-year actuarial survival according to the N status was 65.0% in N0, 30.4% in N1, and 17.9% in N2. There was no statistically significant difference in survival between N1 and N2 diseases (p=0.06). The patients with metastasis to aortic node alone had a comparatively good prognosis (5-year survival: 35.6%) than other N2 diseases (5-year survival: 4.6%) (p=0.01) and had a similar survival outcome as N1 diseases (p=0.97). Considering the aortic node as N1 node, 5-year survival according to the N status was 65.0% in N0, 31.2% in N1, 4.6% in N2 and significant survival difference was observed between N1 and N2 disease (p=0.00). In multivariate analysis, the male sex (hazard ratio 6.892, p=0.011) and the involvement to the aortic node alone (hazards ratio 2.799, p=0.009) were the significant factors affecting postoperative survival. Conclusion: According to the our data, involvement to the aortic node alone in left upper lobe tumors should be grouped with N1 disease because this combined category reflects the surgical outcome more accurately.

Nutrient regime, N:P ratios and suspended solids as key factors influencing fish tolerance, trophic compositions, and stream ecosystem health

  • Kim, Seon-Young;An, Kwang-Guk
    • Journal of Ecology and Environment
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    • v.38 no.4
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    • pp.505-515
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    • 2015
  • The objectives of this study were to determine the effects of stream nutrient regime, N:P ratios and suspended solids on fish tolerance/trophic compositions and stream ecosystem health, based on multi-metric model, during 2008-2013. Also, stream ecosystem health was evaluated in relation to chlorophyll-a (CHL) as a measure of algal productivity or indicators of trophic state to water chemical parameters. Total number of sampled fish species were 50 and showed a decreasing trend from 2008 to 2013. The minnow of Zacco platypus, based on the catch per unit effort (CPUE), was the most dominant species (25.9%) among the all species. Spatial heterogeneity was evident in the fish tolerance guilds that showed the dominance of sensitive species (89%) in the headwaters (S1) and the dominance of tolerant species (57%) in the urban. These conditions were directly influenced by concentrations of nutrients and organic matter (COD). The N:P ratios, as a barometer of water pollution, had a negative linear function (R2 = 0.40, P < 0.01) with CHL, and the ratios had an important role in changes of COD concentration (R2 = 0.40, P < 0.01). Under the circumstances, the N:P ratio directly influenced the relative proportions of fish trophic/tolerance compositions. According to the regression analysis of omnivore (Om) and insectivore sp. (In) on total nitrogen and total phosphorus, nitrogen had no significant influences (P > 0.05) to the two compositions, but phosphorus influenced directly the two guilds [slope (a) = -32.3, R2 = 0.25, P < 0.01 in the In; a = 40.7, R2 = 0.19, P < 0.01 in the Om]. Such water chemistry and fish trophic guilds determined the stream ecosystem health, based on the multi-metric fish model.

Changes in the Total Lipid, Neutral Lipid, Phospholipid and Fatty Acid Composition of Phospholipid Fractions during Pastirma Processing, a Dry-Cured Meat Product

  • Aksu, Muhammet Irfan;Dogan, Mehmet;Sirkecioglu, Ahmet Necdet
    • Food Science of Animal Resources
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    • v.37 no.1
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    • pp.18-28
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    • 2017
  • Pastirma is a dry-cured meat product, produced from whole beef or water buffalo muscles. This study was carried out to investigate the effect of production stages (raw meat, after curing, after $2^{nd}$ drying and pastirma) on the total lipid, neutral lipid, phospholipid and fatty acid composition of phospholipid fraction of pastirma produced from beef M. Longissimus dorsi muscles. The pH and colour ($L^*$, $a^*$ and $b^*$) analyses were also performed in raw meat and pastirma. It was found that pastirma production stages had significant effects (p<0.01) on the total amounts of lipid, neutral lipid and phospholipid, and the highest amounts of lipid, neutral lipid and phospholipid were detected in pastirma. In pastirma, neutral lipid ratio was determined as $79.33{\pm}2.06%$ and phospholipid ratio as $20.67{\pm}2.06%$. Phospholipids was proportionately lower in pastirma than raw meat. Pastirma production stages affected pentadecanoic acid (15:1) (p<0.01), linoleic acid (18:2n-6) (p<0.05), ${\gamma}-linoleic$ acid (18:3n-6) (p<0.05), erucic acid (22:1n-9) (p<0.05), docosapentaenoic acid (22:5n-6) (p<0.05), total unsaturated fatty acid (${\Sigma}USFA$) (p<0.05) and total saturated fatty acid (${\Sigma}SFA$) (p<0.05) ratios of phospholipid fraction and also the moisture content (p<0.01). Pastirma process also affected pH and colour ($L^*$, $a^*$ and $b^*$) values (p<0.01), and these values were higher in pastirma than raw meat.

A Study on Landfill Leachate Treatment by Reduced Pressure Evaporation. (감압증발법을 이용한 매립장 침출수 처리에 관한 연구)

  • 문추연;은종극;이태호
    • Journal of environmental and Sanitary engineering
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    • v.12 no.3
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    • pp.73-79
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    • 1997
  • This research was intended as an investigation of applying Reduced Pressure Evaporation as efficient treatment method for landfill leachate. According to the variance of time, temperature, pressure and pH in experiments, the properties of leachate treatment are follows. The removal efficiencies of COD, NH$_{3}$-N, TOC, Conductivity and SS on the basis of reaction time was 96.4%-97.5%, -1.4%-53.7%, 81.7%-89.0%, 92.0%-95.3% and 99.86%-99.97%, respectively. When the pH of Influent was 7.5, the pH of effluent was increased to 10-11 with time elapse. It is concluded that the orgin of pH increase may be ammonia. When the properties of concentrate were investigated at the concentration ratio 90%(V/V), concentration difficiency represented in the ratio of experimental value/calculated value had following orders ; COD>TOC>NH$_{3}$-N>Conductivity>SS. Concentrate had good precipitation because of additive thermal treatment in the process. When evaporation experiments with pH adjustment of 4.0, 6.0, 7.5, 9.0 and 10.0 were performed ; Acidic evaporation experiments(pH 4.0, 6.0) showed low removal efficiency(81.6, 87.6%) of COD and high removal efficiency (97.5%. 84.6%) of NH$_{3}$-N at initial evaporation. Basic evaporation(pH 9.0, 10.0) showed high removal efficiency (97.2%, 98.9%) of COD and very low removal efficiency (-7.4%, -27.2%) of NH$_{3}$-N at initial evaporation.

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Influence of Dietary Conjugated Linoleic Acid and Its Combination with Flaxseed Oil or Fish Oil on Saturated Fatty Acid and n-3 to n-6 Fatty Acid Ratio in Broiler Chicken Meat

  • Shin, D.;Kakani, G.;Karimi, A.;Cho, Y.M.;Kim, S.W.;Ko, Y.G.;Shim, K.S.;Park, Jae-Hong
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.9
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    • pp.1249-1255
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    • 2011
  • This study examined the effect of CLA, flaxseed oil and fish oil and their combination forms on crude fat of liver and fatty acid profiles of liver, breast and thigh meat in broiler chicks. A total of 72, 1-day-old Cobb broilers were assigned to 6 groups, and fed an experimental diet supplemented with 5 different fat sources; conjugated linoleic acid (2% CLA), flaxseed oil (2% FXO), fish oil (2% FHO), CLA and flaxseed oil combination (1:1; 2% CXO), and CLA and fish oil combination (1:1; 2% CHO). Eight birds per treatment were processed, and liver, breast and thigh samples were investigated at 21 d of age. As a result of this study, most fatty acids of liver, breast and thigh meat were influenced by fat sources supplemented in the diet (p<0.05). CLA addition resulted in an increase of crude fat and saturated fatty acid (SFA) content but a concomitant decrease in n-3 to n-6 fatty acid ratio was observed in liver (p<0.05). Moreover, the same trends of SFA and n-3 to n-6 fatty acid ratio were also observed in breast and thigh meats of birds fed CLA alone. In the CXO-fed group or CHO-fed group, n-3 and n-3 to n-6 fatty acid ratio in both breast and thigh meat increased compared with CLA group, while SFA content decreased (p<0.05). FHO fed-groups had the lowest proportion of n-6 fatty acid in both breast and thigh meats compared to other fat source treatments (p<0.05). In conclusion, the increased levels of crude fat and SFA in liver and meats obtained by feeding CLA could be reduced by its combination with FXO or FHO. In addition, the combination of CLA and FXO or FHO fed to broiler chicks could increase the n-3 to n-6 fatty acid ratio of their meat along with the deposition of CLA.

Decay Rate and Nutrient Dynamics during Litter Decomposition of Quercus acutissima in Gongju and Jinju (공주와 진주지역에서 상수리나무 낙엽의 분해율 및 분해과정에 따른 영양염류 함량 변화)

  • Won, Ho-Yeon;Oh, Kyung-Hwan;Mun, Hyeong-Tae
    • Journal of Wetlands Research
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    • v.14 no.4
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    • pp.537-545
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    • 2012
  • Decay rate and nutrient dynamics during leaf litter decomposition of deciduous Quercus acutissima were compared between Gongju and Jinju for 33 months from December 2008 through March 2011. Percent remaining weight of Q. acutissima leaf litter after 33 months elapsed in Gongju and in Jinju was $41.2{\pm}0.4%$ and $28.3{\pm}0.6%$, and decay constant (k) was 0.39 and 0.61, respectively. Decomposition in Jinju was significantly faster than that in Gongju. This seemed to be related to higher temperature and precipitation in Jinju than those in Gongju during the experimental period. Initial C/N and C/P ratio of Q. acutissima leaf litter was 46.8 and 270.9, respectively. After 33 months elapsed, C/N and C/P ratios in Gongju decreased to 22.0 and 106.8, and those in Jinju decreased to 19.2 and 170.2, respectively. Initial concentration of N, P, K, Ca and Mg in Q. acutissima leaf litter was 8.31, 0.44, 4.18, 9.38, 1.37 mg/g, respectively. After 33 month elapsed, remaining N, P, K, Ca and Mg were 91.0, 85.4, 30.2, 47.9, 11.7% in Gongju, and 67.0, 54.2, 19.9, 30.0, 40.8% in Jinju, respectively. Except for Mg, remaining nutrients of decomposing leaf litter in Jinju were lower than those in Gongju. In case of N and P, initial immobilization was observed, however, only mineralization was observed in K, Ca and Mg during the whole experimental period.

Effect of $NO_3-N$ : $NH_4-N$ Ratio in Nutrient Solution on Growth, Yield and Fruit Quality of Strawberry 'Akihime' in Hydroponic System (딸기 수경재배에서 $NO_3-N$$NH_4-N$의 비율이 '장희(章姬)'의 생육, 수량 및 과실의 품질에 미치는 영향)

  • Jun, Ha-Joon;Hwang, Jin-Gyu;Son, Mi-Ja;Yoon, Hae-Suk
    • Journal of Bio-Environment Control
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    • v.18 no.1
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    • pp.40-45
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    • 2009
  • The experiment has investigated the effects of growth, yield, fruit quality and cation absorption of strawberry 'Akihime' in different $NO_3-N:NH_4-N$ ratio in nutrient solution. $NO_3-N:NH_4-N$ ratios were 5.5:0, 4.0:1.5 and $3.0:2.5me{\cdot}L^{-1}$. As the ratio of $NH_4-N$ increased, pH was decreased by $5.0{\sim}6.0$ and EC sustained $0.8{\sim}1.0dS{\cdot}m^{-1}$ during experiment. Though in high $NH_4-N$ ratio of $3.0:2.5me{\cdot}L^{-1}$, the absorption of cations(K, Ca and Mg) was not inhibited. Treatment in contained $NH_4-N$ showed a tendency of increasing of petiole length and leaf width. The fruit length, fruit width, fruit weight and soluble solids were not significantly different. Yield per plant was lowest in $4.0:1.5\;me{\cdot}L^{-1}$, of $NO_3-N:NH_4-N$ ratio. Malformation fruit has not shown during the whole growth period.