• Title/Summary/Keyword: N:P ratio

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Effect of n-6/n-3 fatty acid ratio on hepatic glycerolipid partitioning in second generation rats (n-6/n-3 지방산 비율이 차세대 랫드의 지질대사 분할에 미치는 영향)

  • Park, Byung-Sung
    • Journal of the Korean Applied Science and Technology
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    • v.34 no.4
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    • pp.839-850
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    • 2017
  • The objective of this study was to investigate the effect of diets with different omega-6 (n-6) and omega-3 (n-3) fatty acid ratios (0, 1.2: 1, 8: 1, 19: 1) on mechanisms of partitioning of in vivo hepatic glycerolipid metabolism in next generation rats. Biomonitoring techniques were used in rats (jugular vein cannula were attached). The range of $^{14}CO_2$ exhaled by glycerolipid metabolism was 7.05-20.17% in the group having diet with n-6/n-3 ratio less than 8:1. It was the lowest in the control group. Total glycerolipid was the highest in the control group. For groups with different n-6/n-3 ratio, it had the following order: 19:1>8:1>1.2:1. Secreted triglyceride was decreased by 36.35%, 20.93%, and 13.72% in 1.2:1,8:1, and 19:1 groups, respectively, compared to that in the control group. The ratio of phospholipid to total glycerolipid was 1.38, 1.29, and 1.17 times higher in 1.2:1, 8:1, and 19:1 groups, respectively, compared to that in the control group. The ratio of $^{14}CO_2$ to total glycerolipid was 1.61, 1.52, and 1.29 times higher in 1.2:1, 8:1, and 19:1 groups, respectively, compared to that in the control group.

Effects of Dietary Fat Levels on Lipid Parameters and Eicosanoids Production of Rats under Fixed N-6/N-3 and P/S Fatty Acid Ratios

  • Lee, Joon-Ho;Ikuo Ikeda;Michihiro Sugano
    • Nutritional Sciences
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    • v.5 no.4
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    • pp.184-189
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    • 2002
  • The effects of dietary Int levels on lipid metabolism under fixed P/S (1.3) and n-6/n-3 (5.1) fatty acid ratios were examined in rats using palm oil, soybean oil and perilla oil. These ratios correspond to the recommended composition of dietary fat for humans. The range of dietary fat levels was 5-20% by weight (11.8-39.3% of total energy). The levels of dietary fat did not influence the concentrations of serum and liver cholesterol, whereas the level of triglycerides was gradually elevated with increasing levels of dietary fat, especially in the liver. The fatty acid composition of tissue phosphatidylcholine seemed to vary with the different levels of fat. The ratio of linoleic acid to arachidonic acid was increased more significantly in the heart than in the liver. In adipose tissue total lipids, the percentages of saturated and monounsaturated fatty acids decreased, whereas the percentage of polyunsaturated fatty acid increased, with increasing dietary Int levels. In addition, though the level of aortic prostacyclin was not uniformly affected by increasing dietary fat levels, thromboxane A2 production by platelets tended to increase with higher levels of dietary fat, suggesting an increased risk of thrombosis in this situation. Thus, even though dietary fat may have desirable compositions of fatty acids, these excessive consumption can produce unfavorable metabolic responses.

Effect of Plant Coverage on the Treatment Efficiency of Nitrogen and Phosphorus in Vegetative Filter Strips (식생피도가 식생여과대의 질소 및 인 처리효율에 미치는 영향)

  • Lee, Byungsoo;Gil, Kyungik
    • Journal of Korean Society on Water Environment
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    • v.24 no.4
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    • pp.499-503
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    • 2008
  • In order to control the non-point source pollution, a vegetative filter strips (VFS) was set up and the site-monitoring was performed. The objective of this study is to investigate the influence of the plant coverage on treatment efficiency of total nitrogen (T-N) and total phosphorus (T-P) using vegetative filter strips. According to the results, it seemed that the treatment efficiencies of T-N and T-P were closely related with the plant coverage ratio. The results showed that treatment efficiency of T-P average 50% at higher than 50% of the plant coverage and 20~23% at lower than 50% of the plant coverage. Also, the treatment efficiency of T-N increased with the increase of the plant coverage ratio.

Study of Dietary Fatty acids, Blood Fatty Acid Composition, and Immune Parameters in Atopic Dermatitis Patients (아토피 피부염 환자의 지방산 섭취와 혈중 지방산 조성 및 면역 지표에 관한 연구)

  • Chung Yun Mi;Kim Sujung;Kim Nack-In;Lee Eun-Young;Choue Ryowon
    • Journal of Nutrition and Health
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    • v.38 no.7
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    • pp.521-532
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    • 2005
  • The prevalence of atopic dermatitis (AD) continues to rise in industrialized countries related to Western lifestyle, including dietary habits, especially imbalance of intake of dietary fatty acids. The purpose of this study was to evaluate the dietary fatty acids and the assess the blood fatty acid composition and immune parameters in AD patients. AD (n = 50) patients and gender ${\cdot}$ age matched healthy controls (HC) were studied in case-control clinical trail. Current fatty acids intake status was determined by 3-day food record method. Blood sample were collected from 30 subjects in each group and blood fatty acid composition and immune parameters were analysed. AD patients consumed less PUFA and their n-6/n-3 PUFA ratio was higher than that of HC. Both the ratios of PUFA and MUFA were positively correlated with SCORAD in AD patients (p < 0.05). In the AD patients, there were abnormalities in the fatty acid composition of the RBC and WBC, SFA being significantly high and most n-3 PUFA being significantly low. Moreover, both the ratios of EPA and DHA in WBC were negatively correlated with dietary n-6/n-3 PUFA ratio in AD patients (p < 0.05). Serum total IgE and IL-4 levels of AD patients increased significantly compared with the levels of HC (p < 0.01). Ratios of monocyte and eosinophil in WBC of AD patients increased significantly compared with the levels of HC including total WBC count (p < 0.01), and ratios of Iymphocyte and basophil in WBC of AD patients decreased significantly compared with the levels of HC (p < 0.05). Moreover, the ratios of eosinophil in WBC were positively correlated with dietary P/M ratio (p < 0.05), and the ratios of monocyte in WBC were positively correlated with n-6/n-3 PUFA ratio (p < 0.05) in AD patients. This results indicated that AD patients had significantly high intake of dietary n-6/n-3 PUFA compared with HC. Imbalance of intake of dietary fatty acids affected fatty acid compositions in the RBC and WBC, and these lead to immune imbalance and grow worse of AD.

Effect of C/N Ratio on the Production of Poly(3-hydroxyalkanoates) by the Methylotroph Paracoccus denitrificans

  • Kim, Byung-Ki;Yoon, Sung-Chul;Nam, Jae-Do;Lenz, Robert-W.
    • Journal of Microbiology and Biotechnology
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    • v.7 no.6
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    • pp.391-396
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    • 1997
  • Two series of carbon sources, linear primary $C_1$~$C_9$ alcohols and linear $C_2$~$C_{10}$ monocarboxylic acids were tested for PHA synthesis in Paracoccus denitrificans. The results showed that the growth-associated synthesis of PHA could be referred only to the carbon sources with odd number of carbon except methanol. For all carbon sources with even number of carbon, nitrogen limitation was required to induce PHA synthesis in P. denitrificans. Poly(3-hydroxyvalerate)[P(3HV)] homopolymer was synthesized from $C_5$, $C_7$, and $C_9$ while growing in the presence of nitrogen, but the nitrogen depletion in the later growth period incorporated 3-hydroxybutyrate(3HB) unit into the polymer chain. The optimum C/N ratio for P(3HV) homopolymer production was found to be 10 when the strain was grown on 10 ml/l of valeric acid for 96 h. P. denitrificans synthesized P(3HB-co-3HV) copolymers from n-hexanoic and n-octanoic acid. The microstructural characterics of the P(3HB-co-3HV) copolymer from n-propanol was investigated using $^13C$-nuclear magnetic resonance spectroscopy, showing a structural heterogeneity.

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Prognostic Significance of Pre-operative FDG-PET in Colorectal Cancer Patients with Hepatic Metastasis (대장직장암 간전이 환자에서 수술전 FDG PET의 예후인자로서의 중요성)

  • Lee, Hyo-Sang;Lee, Won-Woo;Kim, Duck-Woo;Kang, Sung-Bum;Lee, Kyoung-Ho;Lee, Keun-Wook;Kim, Jee-Hyun;Kim, Sang-Eun
    • Nuclear Medicine and Molecular Imaging
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    • v.43 no.5
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    • pp.429-435
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    • 2009
  • Purpose: The purpose of this study was to assess the prognostic value of preoperative FDG-PET in colorectal cancer (CRC) patients with hepatic metastasis (HM). Materials and Methods: 24 CRC patients (M:F=14:10; age, $63{\pm}10$ yrs) with HM who had undergone preoperative FDG PET were included. Cure-intent surgery was performed in all the patients and HMs were controlled using resection (n=13), radio-frequency ablation (RFA) (n=7), and resection plus RFA (n=4). Potential prognostic markers tested were maxSUV of primary tumor, maxSUV of HM, maxSUV ratio of HM over primary tumor (M/P ratio), histologic grade, CEA level, venous/lymphatic/nerve invasion, T stage, N stage, no. of HM, no. of lymph node metastasis, and treatment modality of HM. Results: 14 CRC patients developed a recurrence with a median follow-up duration of 244 days, whereas 10 patients did not develop recurrence with a median follow-up duration of 504 days. M/P ratios but other potential prognostic markers were significantly higher in the recurrent patients ($0.72{\pm}0.14$) than recurrence-free patients ($0.54{\pm}0.23$) (p=0.038). M/P ratio only was found to predict recurrence by Cox multivariate analysis (hazard ratio 37.7, 95% confidence interval 2.01-706.1, p=0.016). The 11 patients with lower M/P ratio of <0.61 had significantly better disease-free survival rate than the 13 patients with higher M/P ratio (${\geq}0.61$) (p=0.026). Conclusion: maxSUV ratio of HM over primary tumor (M/P ratio) may be useful for prognosis prediction of CRC patients with HM. Higher FDG uptake of HM than that of primary tumor may indicate a more advanced status in stage IV CRC.

Removal Efficiency of Pollutants in Agricultural Wastewater by Constructed Wetlands on Reclaimed Land in the Goheung Bay (고흥만 간척지 내 인공습지에 의한 농경배수 정화효율에 관한 연구)

  • Yu, Hun-Sun;Kang, Dong-Hwan;Kwon, Byung-Hyuk
    • Journal of Wetlands Research
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    • v.11 no.3
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    • pp.37-47
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    • 2009
  • This research was conducted at the constructed wetland in Goheung reclaimed land, and water quality components were measured at the 12 points in 15 March 2008 and 10 January 2009, respectively. Temperature, pH, DO, EC and salinity components were measured at the field, and TOC, Cl-, COD, TSS, T-P and TN components were analyzed laboratory. Concentrations of field measured components at inflow points were higher than in constructed wetland. TOC concentration ratio of inflow water to constructed wetland water was higher in January, and Cl concentration ratio of it was higher in March. And, COD concentration ratio of it were 1.37 for March and 1.49 for January, respectively. T-P and T-N concentration ratios of it at inflow points were higher 3 times than in constructed wetland. Constructed wetland attenuated concentration of contaminated components inflow to it. Removal efficiencies of Cl-, T-P and T-N components in inflow water were high at the constructed wetland. removal efficiencies of Cl component were 83% for 1st monitoring and 76% for 2nd monitoring, this removal efficiency be caused by dilution effect of constructed wetland. removal efficiencies of T-P component were 67% for 1st monitoring and 69% for 2nd monitoring, and they of T-N component were 100% for 1st monitoring and 95% for 2nd monitoring. Abnormal removal efficiency of T-N component is caused that nitrogen in inflow water was a little. Removal efficiency of T-P component was higher in January, and T-N component was higher in March. This is caused by environmental difference between growing season and winter.

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The long-term decay rate and nutrient dynamics during leaf litter decomposition of Pinus densiflora and Pinus thunbergii (한반도 중부지역 조림지 소나무와 곰솔의 장기적 낙엽 분해율 및 분해과정에 따른 영양염류 동태변화)

  • Lee, Il-hwan;Jo, Soo-un;Lee, Young-sang;Won, Ho-yeon
    • Korean Journal of Environmental Biology
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    • v.39 no.3
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    • pp.374-382
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    • 2021
  • In the present study, we analyzed the decay rate and nutrient dynamics during leaf litter decomposition of Pinus densiflora and Pinus thunbergii in Gongju for 60 months, from 2014 to 2019. P. thunbergii leaf litter decomposed faster than that of P. densiflora. The decay constant of P. densiflora and P. thunbergii leaf litter after 60 months was 3.02 and 3.59, respectively. The initial C/N ratio of P. densiflora and P. thunbergii leaf litter were 14.4 and 14.5, respectively. After 60 months, C/N ratio of decomposing P. densiflora and P. thunbergii leaf litter decreased to 2.26 and 3.0, respectively. The initial C/P ratio of P. densiflora and P. thunbergii leaf litter were 144.1 and 111.3. After 60 months elapsed, the C/P ratio of decomposing P. densiflora and P. thunbergii leaf litter decreased to 40.1 and 45.8, respectively. After 60 months, the percentage of the remaining N, P, K, Ca, and Mg in decomposing P. densiflora leaf litter was 231.08, 130.13, 35.68, 48.58, and 36.03%, respectively. After 60 months, the percentage of the remaining N, P, K, Ca, and Mg in decomposing P. thunbergii leaf litter was 143.91, 74.02, 28.59, 45.08, and 44.99%, respectively. The findings of the present study provide an insight into the forest ecosystem function of coniferous forests through the analysis of the amount of nutrient transfer into the soil through a long-term decomposition process; this information is intended to be used as basic data for preparing counter measures for future climate and ecosystem changes.

Neutrophil-lymphocyte Ratio Findings and Larynx Carcinoma: a Preliminary Study in Turkey

  • Duzlu, Mehmet;Karamert, Recep;Tutar, Hakan;Karaloglu, Furkan;Sahin, Melih;Cevizci, Rasit
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.1
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    • pp.351-354
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    • 2015
  • Background: To identify the potential prognostic role of the neutrophil/lymphocyte (N/L) ratio in larynx carcinoma. Materials and Methods: Oncologic archive charts of patients with a larynx carcinoma diagnosis between the years 2010 and 2013 were retrospectively reviewed. The inclusion criterion was to be available with hemogram test prior to diagnostic procedure. Patients undergoing septorinoplasty comprised the control group. Results: There were 65 cases in the study and 42 cases in control group meeting inclusion criteria. In general a non-significant increase in N/L ratio was observed with increasing tumor size and stage (p>0.05) in larynx carcinoma. The N/L ratio was found to be significantly higher in larynx carcinoma compared to control group (p=0.004). Conclusions: In conclusion, the N/L ratio was shown to be significantly increased in larynx carcinomas compared to control group. Further studies are needed to assess any prognostic role.

A Comparison of Nitrogen Cycling among Young Pinus koraiensis Plantations of Different Ages (잣나무 유림의 수령에 따른 질소순환의 비교)

  • Cho, Kang-Hyun;Kim, Joon-Ho
    • The Korean Journal of Ecology
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    • v.12 no.4
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    • pp.245-256
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    • 1989
  • Nitrogen cycling was in vestigated in Piuns koraiensis plantations with different ages, 1, 2, 3, 6, 9 and 11 years, which were reforested after clear-cutting. Annual N input by bulk precipitation was 10kg., and output by runoff decreased as the plantation aged, especially in-N. The standing N content of the whole vegetation increased approximately 5 times through 11 years. Understory surpassed P. koraiensis plants in the distribution of standing N content for the initial 9 years, but reversed thereafter. Annual N uptake of P. koraiensis plants increased greatly through 11 years, but that of understory increased somewhat until 9 years and decreased thereafter. The maximum N uptake of the whole vegetation was made in the 9-yr-old plantation. In the 1-yr-old one, 59% of the maximum was already absorbed by understory which mainly consisted to herbs. The recycling coefficient, ratio of annual return to rptake, of the whole vegetation decreased as the plantation aged and the value of understory was greater than that of P koraiensis plants. On the contrary, the N use efficiency, ratio of the net primary production to N uptake, of the whole vegetation increased as the plantation aged and the value of understory was less than that of P. koraiensis plants. Consequently, it is emphasized that understory played an important role in such plantation reforesred after clear-cutting for the initial 9 years.

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