• Investigative Magnetic Resonance Imaging
• /
• 제21권4호
• /
• pp.252-258
• /
• 2017

Primary mesenteric liposarcoma is rare. It is difficult to make an accurate preoperative diagnosis of the myxoid type of liposarcoma by using imaging such as ultrasound or computed tomography (CT) due to the very small amount of fat that is located in the tumor. We report a case of primary myxoid liposarcoma of the mesentery which was difficult to differentiate from other solid mesenteric tumors with a myxoid component such as low grade fibromyxoid sarcoma, myxoid leiomyosarcoma or myxoma. Use of chemical shift magnetic resonance (MR) imaging to detect small fat components and its cystic appearance with solid components on the MR images can be useful to differentiate myxoid liposarcoma from the other mesenteric tumors with a myxoid component.

• 대한세포병리학회지
• /
• 제1권2호
• /
• pp.185-190
• /
• 1990

The cytologic findings in fine needle aspiration of a case of myxoid liposarcoma of the mediastinum are described. The smear and cell block of the aspirate revealed solid clusters with background of amorphous material and scattered single tumor cells. The clusters were moderately cellular and consisted of atypical lipoblasts in varying stages of differentiation and delicate plexiform capillaries. Good correlation was found between the histologic and cytologic findings in the fine needle aspirates. The differential diagnosis between myxoid liposarcoma and other myxoid soft tissue tumors is discussed.

• 대한수의학회지
• /
• 제54권1호
• /
• pp.63-66
• /
• 2014

The pathological features of a mass in the back skin region of an 8-year-old castrated male dog are described herein. The cut section of the tumor was white to tan with a soft multilobulated mass containing hemorrhagic and necrotic foci and a mucinous-like composition. Microscopically, the tumor was composed of a mixture of lipocytes, lipoblasts, spindle cells and stellate cells and had a myxoid background. Oil red O staining revealed that the cytoplasm of neoplastic cells contained large numbers of lipid droplets. Immunohistochemically, tumor cells were positive for vimentin and S-100 protein. The skin mass was diagnosed as myxoid liposarcoma.

• 대한두경부종양학회지
• /
• 제37권2호
• /
• pp.71-75
• /
• 2021

Liposarcoma is a very rare malignant tumor affecting the head and neck area. Since it is an invasive and life-threatening disease, active treatments is necessary. However, differential it from lipoma, its corresponding benign counterpart, may be difficult. Herein, we report a rare case of posterior neck myxoid liposarcoma in a 72-year-old man who was initially misdiagnosed with lipoma, including a literature review of differential diagnosis between lipoma and liposarcoma.

• Journal of Korean Neurosurgical Society
• /
• 제48권3호
• /
• pp.276-280
• /
• 2010

Liposarcomas are malignant tumors of the soft tissue, with myxoid liposarcoma being the second most common subtype, tending to occur in the limbs, particularly in the thighs. Myxoid liposarcomas have an intermediate prognosis between well-differentiated and pleomorphic tumors. Spinal metastasis is usual but intradural involvement is extremely rare. We present an unusual case of a multicentric myxoid liposarcoma with intradural involvement. A 41-year-old woman complained of tingling sensation on her left arm. Radiological evaluation revealed multiple masses in her cervical spine, abdominal wall, liver, heart and right thigh, all of which were resected. She was histologically diagnosed with small round cell myxoid sarcoma and underwent adjuvant chemotherapy. However, magnetic resonance imaging analysis after 1 year revealed a large metastatic mass with bony invasion at the C6-T1 level. This mass consisted of extradural and intradural components causing severe compression of the spinal cord. She underwent resection via a posterior facetectomy of C6-7 and an anterior C7 corpectomy. However, the patient died of multiple metastases 18 months after the first diagnosis.

• 대한수의학회지
• /
• 제60권2호
• /
• pp.97-100
• /
• 2020

A 7-year-old Maltese was presented to a veterinary clinic for a history of anorexia, soft feces, and anemia. During abdominal sonography and computed tomography imaging, splenic mass was suspected. Laparotomy revealed the bloody ascites, and the enlarged spleen containing a large spherical mass. Microscopically, the splenic parenchyma was replaced by neoplastic cells with cytoplasmic vacuolation and abundant myxoid matrix. Cellular vacuolation and myxoid matrix were positive to Oil-Red-O and Alcian-blue stains. The neoplastic cells were positive to vimentin on immunohistochemistry. The case was diagnosed as myxoid liposarcoma. Based on a poor prognosis, the dog was euthanized three weeks after splenectomy.

• 대한영상의학회지
• /
• 제84권4호
• /
• pp.952-957
• /
• 2023

유방에 발생하는 점액성 지방육종은 극히 드문 유방의 악성종양이다. 저자들은 엽상종양의 과거력이 있는 44세 여자 환자에서 발생한 유방 점액성 지방육종의 1예를 보고하고 유방촬영술, 초음파, 자기공명영상의 영상 소견을 보고하고자 한다. 종양은 수술 전 영상검사에서 엽상종양의 재발로 오인되었으나 후향적으로 비교했을 때 점액성 지방육종과 엽상종양의 감별에 도움이 될 수 있는 초음파 소견을 고찰하였다.

• Archives of Plastic Surgery
• /
• 제38권4호
• /
• pp.505-507
• /
• 2011

Purpose: Liposarcoma is the most common soft tissue sarcoma, and usually occurs on the thigh or in the retroperitoneal space, but rarely in the oral region. This report presents a case of liposarcoma of the cheek and includes a review of the literatures. Methods: A 21-year-old woman was admitted with a palpable mass in her cheek of about two years duration, which increased in size gradually initially, but had increased rapidly over the three months. There was no particular pain or tenderness. MRI showed a well-enhanced, well-defined mass, which suspected to be hemangioma. Results: The spherical, well-encapsulated mass was surgically excised. Biopsy results revealed myxoid liposarcoma. FDG PET-CT on the seventh postoperative day, revealed a minimal to mild FDG-uptake soft tissue lesion around the mass defect area without evidence of distant metastasis. The patient is being observed and undergoing radiation therapy. Conclusion: Liposarcoma in the head and neck region is a rare disease, and can be overlooked as a benign tumor without a pathologic diagnosis. Therefore, proper treatment and follow-up are required based on an understanding of this disease.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제16권3호
• /
• pp.309-314
• /
• 1994

지방육종은 주로 근간 간엽조직으로부터 발생되어지며, 중년이상의 남성에서 호발하고 주된 발병부위는 하지 및 후복막강이고 구강 주위조직에 이환되는 경우는 극히 드문 악성종양이며, 본 증례에서는 4년 전 좌측 하지에서 발생되어 우측 하지 및 좌측 협부에 전이된 것으로 생각되어지는 점액양의 지방육종으로 종물의 외과적 절제술 및 화학요법을 시행하였고 장기적인 관찰이 요구된다.

• 대한정형외과학회지
• /
• 제54권5호
• /
• pp.440-446
• /
• 2019

목적: 본 연구의 목적은 사지에 발생한 점액성 지방육종 환자의 치료 결과를 후향적으로 분석하여 생존율과 재발 및 전이의 양상 등 치료 결과를 알아보고, 예후에 영향을 미치는 인자를 분석하고자 한다. 대상 및 방법: 2001년 1월부터 2015년 12월까지 원자력병원에서 점액성 지방육종으로 치료 받은 91명의 환자(일차성 83명, 재발성 8명)를 대상으로 하였다. 치료 후 재발 및 전이 발생 및 생존율 및 생존의 예후 인자를 조사하였다. 평균 추시 기간은 84개월(범위, 5-196)개월이었다. 결과: 전체 환자의 5년 및 10년 생존율은 82%, 10년 생존율은 74%였다. 일차성 환자에서 생존율에 영향을 미치는 인자는 종양의 크기(p=0.04), 원형 세포 분포 정도(p<0.0001), 병리적 등급(p=0.0002), 국소 재발(p=0.006)이었다. 폐외 전이는 전이 환자의 75.0%(18/24)에서 나타났으며 전이 후 평균 생존 기간은 26개월(범위, 2-72개월)이었다. 결론: 점액성 지방육종은 주로 하지에 발생하며 종양의 크기, 병리적 등급, 원형 세포의 분포, 국소 재발 여부가 예후에 영향을 미치고, 다른 일반적인 육종과 달리 폐 이외의 전이를 많이 하는 특징이 있음을 치료 또는 추시중 유의해야 할 것이다.