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http://dx.doi.org/10.14405/kjvr.2014.54.1.63

Myxoid liposarcoma in a dog  

Jeon, Sung-Joo (College of Veterinary Medicine, Chungnam National University)
Cho, Eun-Sang (College of Veterinary Medicine, Chungnam National University)
Noh, Hye-Jin (College of Veterinary Medicine, Chungnam National University)
Son, Hwa-Young (College of Veterinary Medicine, Chungnam National University)
Publication Information
Korean Journal of Veterinary Research / v.54, no.1, 2014 , pp. 63-66 More about this Journal
Abstract
The pathological features of a mass in the back skin region of an 8-year-old castrated male dog are described herein. The cut section of the tumor was white to tan with a soft multilobulated mass containing hemorrhagic and necrotic foci and a mucinous-like composition. Microscopically, the tumor was composed of a mixture of lipocytes, lipoblasts, spindle cells and stellate cells and had a myxoid background. Oil red O staining revealed that the cytoplasm of neoplastic cells contained large numbers of lipid droplets. Immunohistochemically, tumor cells were positive for vimentin and S-100 protein. The skin mass was diagnosed as myxoid liposarcoma.
Keywords
canine myxoid liposarcoma; oil red O stain; PAS stain; S-100; vimentin;
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1 Shanley KJ, Miller WH Jr. Panniculitis in the dog: a report of five cases. J Am Anim Hosp Assoc 1985, 21, 545-550.
2 Andreasen CB, Mahaffey EA, Duncan JR. Intermediate filament staining in the cytologic and histologic diagnosis of canine skin and soft tissue tumors. Vet Pathol 1988, 25, 343-349.   DOI   ScienceOn
3 Baez JL, Hendrick MJ, Shofer FS, Goldkamp C, Sorenmo KU. Liposarcomas in dogs: 56 cases (1989-2000). J Am Vet Med Assoc 2004, 224, 887-891.   DOI   ScienceOn
4 Cheng J, Yu H, Wang L, Wang X, Shen G. Primary oral and maxillofacial liposarcoma: a clinicopathological and immunohistochemical study of eleven cases. Arch Med Sci 2012, 8, 316-323.
5 Daugaard S. Current soft-tissue sarcoma classifications. Eur J Cancer 2004, 40, 543-548.   DOI   ScienceOn
6 Dei Tos AP, Wadden C, Fletcher CDM. S-100 protein staining in liposarcoma: its diagnostic utility in the high-grade myxoid (round cell) variant. Appl Immunohistochem 1996, 4, 95-101.
7 Doster AR, Tomlinson MJ, Mahaffey EA, Jordan CW. Canine liposarcoma. Vet Pathol 1986, 23, 84-87.   DOI
8 Fletcher CDM, Unni KK, Mertens F. Pathology and Genetics of Tumours of Soft Tissue and Bone. pp. 12-40, IARC Press, Lyon, 2002.
9 Ganesh IM, Subramani D, Halagowder D. Mucin glycoarray in gastric and gallbladder epithelia. J Carcinog 2007, 6, 10.   DOI   ScienceOn
10 Weiss SW, Goldblum JR. Liposarcoma. In: Enzinger and Weiss's Soft Tissue Tumors. 4th ed. pp. 641-693, Mosby, St. Louis, 2001.
11 Graadt van Roggen JF, Hogendoorn PCW, Fletcher CDM. Myxoid tumours of soft tissue. Histopathology 1999, 35, 291-312.   DOI
12 Hargis AM, Ginn PE. The integument. In: McGavin MD, Zachary JF (ed.). Pathologic Basis of Veterinary Disease, 4th ed. pp. 1146-1147, Mosby, St. Louis, 2007.
13 Kaneko JJ, Harvey JW, Bruss ML. Clinical Biochemistry of Domestic Animals. 6th ed. pp. 768-771, Academic Press, San Diego, 2008.
14 Nemanqani D, Mourad WA. Cytomorphologic features of fine-needle aspiration of liposarcoma. Diagn Cytopathol 1999, 20, 67-69.   DOI
15 Kwon HJ, Park MS, Kim DY, Cho DY, Yoon BI, Shin NS, Kim DY. Round cell variant of myxoid liposarcoma in a Japanese Macaque (Macaca fuscata). Vet Pathol 2007, 44, 229-232.   DOI   ScienceOn
16 Masserdotti C, Bonfanti U, De Lorenzi D, Ottolini N. Use of oil red O stain in the cytologic diagnosis of canine liposarcoma. Vet Clin Pathol 2006, 35, 37-41.   DOI   ScienceOn
17 Messick JB, Radin MJ. Cytologic, histologic, and ultrastructural characteristics of a canine myxoid liposarcoma. Vet Pathol 1989, 26, 520-522.   DOI   ScienceOn
18 Rabanal RH, Fondevila DM, Montane V, Domingo M, Ferrer L. Immunocytochemical diagnosis of skin tumours of the dog with special reference to undifferentiated types. Res Vet Sci 1989, 47, 129-133.
19 Shmitt FC, Bacchi CE. S-100 protein: is it useful as a tumour marker in diagnostic immunocytohemistry? Histopathol 1989, 15, 281-288.   DOI   ScienceOn
20 Goldschmidt MH, Hendrick MJ. Tumors of the Skin and Soft Tissues: Liposarcoma. In : Meuten DJ (ed.). Tumors in Domestic Animals. 4th ed. pp. 97-99, Iowa State Press, 2002.