• The Journal of Internal Korean Medicine
• /
• v.41 no.2
• /
• pp.248-255
• /
• 2020

Objectives: Fatigue, malnutrition, and weight loss are common complaints after undergoing surgery for cancer. These symptoms can be associated with Yin-Deficiency (陰虛) of Exhaustion syndrome (虛勞). Therefore, this study aimed to determine if it is possible to use Dokhwaljihwang-tang, which originates from Yukmijihwang-tang, for enhanced recovery after cancer surgery. Methods: After cancer surgery, Dokhwaljihwang-tang-gami was administered three times a day, in 80-120 ml doses at a time. Results: In four cases of gastric, colorectal, and thyroid cancer, enhanced recovery was achieved using Dokhwaljihwang-tang-gami to treat general weakness, fatigue, and pain in the surgical site after cancer surgery. Conclusions: Dokhwaljihwang-tang can be used for enhanced recovery after cancer surgery.

• Journal of the Korean Society of Environmental Restoration Technology
• /
• v.17 no.6
• /
• pp.39-50
• /
• 2014

This study was conducted to establish inventory and propose conservation strategy of 'village wetlands' in Cheonan. As results, the village wetlands are defined as such places as palustrine wetland, village embankment, agricultural reservoir or small reservoirs located in or near the village and related to everyday life or farming. Firstly 791 provisional village wetlands were identified in Cheonan by using Arc-GIS 10.1, then 104 wetlands were defined as village wetlands and listed the inventory of Cheonan Village Wetlands after being validated through their area (greater than $1,000m^2$), satellite images, Korea Land Information System, land use map, land coverage map and field survey. Finally the 49 wetlands were selected for detailed surveying, and function assessment. As the result of the wetland function assessments, 11 wetlands were found to have 'high' wetland function (conservation) 30 wetlands were 'average' (enhancement) and 8 wetlands were 'low' (restoration or enhancement). Enhancing biodiversity and ecosystem services through ecological management of wetlands in Cheonan and connecting with an ecological network were proposed.

• The Journal of Internal Korean Medicine
• /
• v.39 no.5
• /
• pp.955-963
• /
• 2018

This case report documents one patient with acute cortical cisternal subarachnoid hemorrhage. The patient had a central pain in the right upper limb and was treated with traditional Korean medicine in the Oriental Hospital of Se-Myung University. The patient was treated with Yangkyuksanwha-tang and acupuncture and followed up with a symptoms checklist and brain computed tomography (CT) scan. Initially, the frequency of right upper extremity pain was 18 per day, but this disappeared after treatment. CT follow up showed that subarachnoid hemorrhage was resolved. There were no side effects associated with treatment. This case shows that traditional Korean medicine treatment is effective in treating acute cortical subarachnoid hemorrhage.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2004.11a
• /
• pp.413-416
• /
• 2004

오늘날의 컴퓨팅 시스템은 비즈니스 거래와 분산 업무 처리로 확대되어가고 있으며 정보 기술은 점차적으로 재사용성과 독립성 그리고 이식성을 가진 컴포넌트를 기반으로 한 응용 개발이 확산되고 있다. 컴포넌트 개발 형태는 코드의 재사용이나 클래스 라이브러리보다 좀 더 발전된 형태의 부품개발 형태로서, CBD(Component Based Development)를 기초로 한다. 그러나 CBD를 이용하여 새로운 컴포넌트를 구축하는 비용의 증가와 함께 비즈니스 요구사항에 맞는 컴포넌트 개발을 위한 노력이 필요하며, 빠르고 정확한 컴포넌트 정보를 지원할 수 있도록 시스템 측면에서 정규화 형태의 컴포넌트 모델이 요구되고 있다. 본 논문에서는 사용자 요구사항에 접근하고, 재사용성과 독립성, 그리고 이식성을 가진 컴포넌트를 추출하고, 컴포넌트를 대상으로 인터페이스 나타내고자 한다. 따라서 본 논문에서는 학부생들을 위한 학생정보시스템 구축을 위한 시스템 분석 및 설계 모델을 RUP(Rational Unified Processing) 방법론을 이용한다.

• The Journal of Internal Korean Medicine
• /
• v.32 no.3
• /
• pp.435-443
• /
• 2011

Fahr disease (FD) is a rare neurological disorder characterized by presence of abnormal and associated cell loss in certain areas of the brain, mostly in basal ganglia, thalamus, cerebellum and subcortical areas. Approximately two-thirds of the patients are symptomatic. The most common neurological manifestations include movement disorders, cognitive impairment, cerebellar signs and speech disorders. We report one case of estimated FD through brain computed tomography (bilateral calcifications of basal ganglia, thalamus, centrum semiovale, subcortical white matter of occipital lobes, cerebellum). At the first time of treatment, he complained of tremors in his upper limbs. We diagnosed the patient as deficiency of qi (氣) and movement of phlegm-heat-wind (痰熱風動) type according to symptoms and treated by herbs and acupuncture of oriental medicine. During treatments, we evaluated how well the oriental medical treatments were working using visual analogue scale (VAS) and amplitude of hands. After the oriental medical treatments about tremor, VAS dropped from 10 to 2 and amplitude of hands from 20 mm to 2 mm, but the ratio of brain calcifications was not changed. This study suggests that oriental medical treatments can be applicable to improve FD.

• The Journal of Internal Korean Medicine
• /
• v.31 no.2
• /
• pp.380-387
• /
• 2010

The ischemic penumbra represents part of the hypoperfused region associated with focal brain ischemia. A practical approach is to define this region as that portion of the ischemic territory that can potentially be salvaged by timely intervention. For the prevention and treatment of ischemic stroke, antithrombotic therapy is prescribed. But medication of antiplatelet agent is only validated as prevention effect. Cheonghyulgangki-tang has been used for cerebral apoplexy, hypertension, etc. In this case report, an acute ischemic stroke patient was treated with an antiplatelet agent named Plavix and Cheonghyulgangki-tang and remarkable reduction of ischemic portion in the brain CT was observed. The result of this case suggests that oriental medical therapy could be a safe and effective intervention in acute ischemic stroke.

• The Korean Journal of Food And Nutrition
• /
• v.21 no.1
• /
• pp.71-78
• /
• 2008

This study examined the effects of mulberry-leaf powder Tofu(MPT) on the anthropometric measurements, bone mineral density(BMD), biochemical markers of bone turnover, serum lipid levels of and macrominerals status in 30 female university students living in Choongnam with low dietary Ca intake was low(mean daily $intake=524.66{\pm}21.47$ mg/day). The subjects received the MPT supplemented(100 g/day) for 4 weeks. The nutrient content per 100 g MPT was 84.10 kcal(energy), 8.98 g(protein), 0.53 mg(fiber), 211.33 mg(Ca) and 1.59 g(fat). Anthropometric measurements, 24-hour dietary recall, carpus BMD using DEXA, select BMD biomarckers(serum alkaline phophatase activity, osteocalcin, urinary deoxypyridinoline), serum protein levels, albumin, and glucose levels, lipid profiles(cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol) and serum macrominerals(Ca, Ca/P ratio, Mg) were analyzed before and after MPT supplementation. Following MPT supplementation, there was no significant differences in anthropometric measurements, nutrient intakes, carpus BMD, serum alkaline phosphatase activity, osteocalcin, and urinary deoxypyridinoline, serum levels of protein, albumin, and glucose or lipid profiles with AI, HTR, LHR and CRF. However, there were significant increases in dietary calcium as well as decreases in serum triglycerides with MPT supplementation. Although further research is needed, these results that regular intake MPT could prevent bone and cardiovascular diseases.

• Proceedings of the Korean Society of Life Science Conference
• /
• 2002.03a
• /
• pp.103-103
• /
• 2002

• The Journal of Internal Korean Medicine
• /
• v.41 no.3
• /
• pp.531-541
• /
• 2020

From January 2014 to December 2016, 38 out of 153 inpatients admitted to the Korean Medicine Hospital for more than one month underwent follow-up blood tests to evaluate their liver function levels, and one drug-induced liver injury (DILI) patient was observed. 1. At the time of admission, six (15.8%) of the 38 patients had abnormal alanine aminotransferase (ALT) levels and five of them recovered after hospitalization. 2. At follow-up, two (5.3%) patients had a Council for International Organizations of Medical Science (CIOMS)-based liver injury. One was identified as a liver injury accompanied by pneumonia, and one was judged as a liver injury caused by the drug. 3. The patient had a suspected DILI and completely recovered after 13 days while discontinuing the herbal medication and by using Sanggangunbi-tang (生肝健脾湯).

• Journal of Life Science
• /
• v.30 no.9
• /
• pp.772-782
• /
• 2020

Skeletal muscle differentiation or myogenesis is important to maintain muscle mass and metabolic homeostasis. Muscle-specific microRNAs (miRNAs) are known to play a critical role in skeletal myogenic differentiation. In this study, we examined the expression profiling of miRNAs during myogenic differentiation in rat L6 myoblasts using rat miRNA microarrays. We identified the upregulated expression of miR-128 as well as several well-known myogenic miRNAs, including miR-1, miR-133b, and miR-206. We additionally confirmed the increased expression of miR-128 observed on microarray through quantitative real-time PCR (qRT-PCR), which showed similarly upregulated expression of both primary miR-128 and mature miR-128, consistent with the microarray findings. Furthermore, transfection of miR-128 into rat L6 myoblasts induced gene expression of myogenic markers such as muscle creatine kinase (MCK), myogenin, and myosin heavy chain (MHC). Protein expression of MHC was increased as well. Inhibition of miR-128 by inhibitory peptide nucleic acids (PNAs) blocked the expression of those myogenic markers. In addition, the transfection of miR-128 into rat L6 myoblasts enhanced the phosphorylation of Erk and Akt proteins stimulated by insulin, while simultaneously reversing the inhibited phosphorylation of Erk and Akt due to insulin resistance. These findings suggest that miR-128 may play important roles in myogenic differentiation and insulin signaling.