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http://dx.doi.org/10.22246/jikm.2020.41.3.531

A Study on the Change of Liver Function Level in Patients Admitted to Korean Medicine Hospital: A Case of One Drug-induced Liver Injury Patient  

Kim, Geun-yeob (Dept. of Internal Medicine, College of Korean Medicine, Se-Myung University)
Jung, Nu-ri (Dept. of Internal Medicine, College of Korean Medicine, Se-Myung University)
Choi, Yu-jin (Dept. of Internal Medicine, College of Korean Medicine, Se-Myung University)
Shin, Seon-mi (Dept. of Internal Medicine, College of Korean Medicine, Se-Myung University)
Kim, Ki-tae (Dept. of Internal Medicine, College of Korean Medicine, Se-Myung University)
Ko, Heung (Dept. of Internal Medicine, College of Korean Medicine, Se-Myung University)
Publication Information
The Journal of Internal Korean Medicine / v.41, no.3, 2020 , pp. 531-541 More about this Journal
Abstract
From January 2014 to December 2016, 38 out of 153 inpatients admitted to the Korean Medicine Hospital for more than one month underwent follow-up blood tests to evaluate their liver function levels, and one drug-induced liver injury (DILI) patient was observed. 1. At the time of admission, six (15.8%) of the 38 patients had abnormal alanine aminotransferase (ALT) levels and five of them recovered after hospitalization. 2. At follow-up, two (5.3%) patients had a Council for International Organizations of Medical Science (CIOMS)-based liver injury. One was identified as a liver injury accompanied by pneumonia, and one was judged as a liver injury caused by the drug. 3. The patient had a suspected DILI and completely recovered after 13 days while discontinuing the herbal medication and by using Sanggangunbi-tang (生肝健脾湯).
Keywords
drug-induced liver injury (DILI); herb; alanine aminotransferase (ALT); CIOMS; traditional Korean medicine (TKM);
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