• 대한임상독성학회지
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• 제2권1호
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• pp.20-22
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• 2004

Acute mercury inhalation poisoning is a rare cause of acute peripheral neuropathy. A 44-year-old female inhaled the fume from heating mercury to treat her palmar dermatitis. For 4 days, this procedure was done for 2-3 minutes after each meal. She subsequently complained flu like symptoms, such as headache, toothache, myalgia and arthralgia. She was admitted for 9 days and then symptoms disappeared. About 3 weeks after exposure, both knee pain developed and then she could not walk. To treat mercury intoxication, she was referred to our hospital. At that time, initial laboratory data were within normal limits, but blood and urinary mercury level were 5.6 11$\mu$g/dl, 132.8 $\mu$g/L. After treatment with D-penicillamine for 7 days, blood and urinary mercury level were 3.9 1$\mu$g/dl, 177.3 $\mu$g/L. During the following 1 month, both leg symptoms remained. Nerve conduction studies were performed, both leg sensory nerve amplitude decreased. These findings were suggestive of peripheral polyneuropathy.

• Journal of Preventive Medicine and Public Health
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• 제25권3호
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• pp.223-237
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• 1992

This study was to examine the association of the health-related behaviors and subjective symptoms with smoking. Data were collected by questionnaire survey during regular health examination from Mar. 23 to Mar. 31, 1992 for 1,615 male freshmen of a university in Kwangju City. The results obtained were as follows : 1. Among the freshmen, 26.9% reported that they were smokers. 69.4% for smokers started smoking for the recent 4 years, and 63.4% for smokers smoked 10 cigarettes or more a day. 2. Meal regularity, meat eating, use of coffee or tea and alcohol drinking were positively associated with the status, the duration and the amount of smoking while the vegetable preference was negatively associated with the status and the duration of smoking. 3. There was no evidence of familial aggregation in smoking status except that of siblings. 4. Respiratory symptoms like cough or phlegm, dyspnea were positively associated with the status, the duration, and the amount of smoking. General symptoms like chest pain, fatigue, back pain, facial edema, and weight loss were positively associated with the duration and the amount of smoking. Other symptoms like headache, dizziness, and myalgia were not associated with smoking. 5. In multivariate logistic regression analysis, cough or phlegm, dyspnea, chest pain, facial edema, and back pain were related to smoking status.

• Tuberculosis and Respiratory Diseases
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• 제70권1호
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• pp.69-73
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• 2011

The combination therapy of pegylated interferon and ribavirin is the mainstay of treatment for chronic hepatitis C patients. Anti-viral therapy is commonly associated with side effects such as headache, fever, myalgia, and arthralgia. However, anti-viral therapy can continue because these side effects are mostly mild and can be improved with supportive management. Anti-viral therapy should be stopped promptly if serious side effects, such as interstitial pneumonitis or hemolytic anemia occur, although those serious side effects are rare. There were a few case reports of interferon-related interstitial pneumonitis worldwide. In Korea, one atypical case report of interstitial pneumonitis has been reported, which followed the combination therapy of interferon-alpha and ribavirin in a patient with chronic hepatitis C. We present a case of interstitial pneumonitis and pancytopenia following the combination therapy of pegylated interferon and ribavirin in a patient with chronic hepatitis C.

• Tuberculosis and Respiratory Diseases
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• 제69권2호
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• pp.124-128
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• 2010

Septic pulmonary embolism is the process in which an infected thrombus becomes detached from its site of origin and lodges in a pulmonary artery, and is usually associated with infective endocarditis, especially right-sided, or infection-associated with indwelling catheters, peripheral septic thrombophlebitis, and periodontal diseases, etc. Here, we report a case of septic pulmonary embolism associated with tricuspid valve infective endocarditis. A 23-year-old female was admitted to our hospital, due to fever, sore throat, and myalgia. In her past medical history, she had undergone a surgical operation for closure of a ventricular septal defect, but was informed that the operation resulted in an incomplete closure. The initial chest radiograph demonstrated multiple rounded, parenchymal nodules in various sizes; several nodules had central lucency suggesting cavitations. Echocardiography demonstrated a large vegetation attached to the septal tricuspid valve leaflet, extending from right ventricular inflow tract to outflow tract. Computed tomography of thorax revealed bilateral peripheral nodules and wedge-shaped consolidation at various sizes, mostly accompanied by cavitations.

• 대한약침학회지
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• 제12권1호
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• pp.43-51
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• 2009

Objective : The purpose of this study is to present the standard for practical application of ginger herbal pharmacopuncture Material and Methods : We refer to ancient literatures and the recent papers for ginger. Conclusions : The following results have been obtained 1. The effect of ginger(Zingiber officinale Roscoe) is to "release exterior", "balance nutrient & defensive qi", "resolve phlegm", "arrest coughing", "warm the lungs". So ginger herbal pharmacopuncture can be applied to treating fever, chilling sign, headchae, snuffle and gasping cough due to cold affection and treating the symptoms like sputum and asthma that be revealed by pulmonary disease. 2. The effect of ginger is to "warm spleen and stomach", "arrest vomiting" "promote normal flow of water". So ginger herbal pharmacopuncture can be applied to treating nausea, vomiting, abdominal distension and diarrhea due to phlegm & dampness and treating edema. 3. The effect of ginger is to eliminate blood stasis. So ginger herbal pharmacopuncture can be applied to treating contusion, blood stasis, sprain and gynecologic disease. 4. Ginger can treat myalgia and pain due to wind-damp and have anti-inflammatory effect in pharmacology. So ginger herbal pharmacopuncture can be applied to treating disease of joint, ligament and muscle. 5. Ginger can resolve phlegm and resuscitate. So ginger herbal pharmacopuncture can be applied to treating unconsciousness. But, treating incipient cardiovascular accident, it needs to call your special attention to the danger of blood pressure increase. 6. In pharmacology, ginger is effective for antitumor, antioxidant effects and activating immunocyte. So ginger herbal pharmacopuncture can be applied to treating broadly varieties of tumor and allergic disease.

• 대한한방내과학회지
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• 제24권2호
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• pp.171-180
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• 2003

Background : Till now Efficacy of Taeyangin medicine have not existsd in Medical Oriental medical, QSCC II(Questionnaire of sasang Constitution Classification II) can't discriminate Taeyangin is known to everybody. Objective : We have made an Effort to find out Essence of Taeyangin's Disease. Method : we have examined patient's feeling of improvement, Disease entity, Term of taking medicine, Period of ilness With eath symptoms, Comparison Taeyangin part Marks of QSSC II with Marks of improved Taeyangin questionnaire. Result : According to 43 Case of Patients Treated with Ogapijangchuk-tang, Ogapijangchuk-tang is more effective to cure Fatigue taking Headache and Dizziness than Myalgia and so on. and Item of more improved Taeyangin's constitution Question is more effective than Item of Taeyanin's constitution question in QSCC II.

• Korean Journal of Acupuncture
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• 제29권1호
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• pp.37-46
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• 2012

Objectives : The gnarl of Pinus densiflora, called Songjeol in Korea, has been used as a medicinal herb for the treatment of inflammatory-related diseases such as arthralgia, myalgia and bruise. However, the molecular actions and mechanisms have not been clearly investigated. The aim of this study was to clarify the anti-inflammatory activity of Pinus densiflora gnarl pharmacopuncture (PDGP) in lipopolysaccharide (LPS)-stimulated RAW264.7 cells. Methods : Cytotoxicity was assessed by XTT assay. The amount of nitric oxide (NO) production was determined by nitrite assay. The mRNA expressions of interleukin-$1{\beta}$ (IL-$1{\beta}$), interleukin-6 (IL-6), cyclooxygenase-2 (COX-2) and heme oxygenase-1 (HO-1) were analyzed by RT-PCR. Reactive oxidative species (ROS) generation was measured using the fluorescence microscopy. In addition, inducible nitric oxide synthase (iNOS) and redox factor-1 (Ref-1) protein expressions were detected by Western blotting. Results : PDGP inhibited NO production and ROS generation in LPS-stimulated RAW264.7 cells. At the mRNA level, PDGP suppressed IL-$1{\beta}$, IL-6 and COX-2 expression. On the other hand, PDGP induced HO-1 mRNA expression. Furthermore, PDGP suppressed iNOS and Ref-1 protein expression. Conclusions : This result suggests that PDGP can act as a suppressor agent on NO and iNOS through induction of HO-1, and play an useful role in blocking inflammatory responses.

• Journal of Yeungnam Medical Science
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• 제31권2호
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• pp.113-116
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• 2014

A 52-year-old man was referred to our hospital due to fever and myalgia that occurred 2 weeks earlier. He showed a complete atrioventricular block on his electrocardiogram, and his vital signs were unstable. On his transthoracic echocardiograph, the 1.5 cm vegetation in the aortic valve with severe aortic regurgitation suggested infective endocarditis. His transesophageal enchocardiograph showed abscess in his mitral-aortic intervalvular fibrosa and vegetation was suspected on his anterior mitral valve leaflet. The patient underwent an emergent operation for valve replacement with temporary epicardial pacing. Intraoperatively, the septal leaflet of his tricuspid valve was injured during the debridement of the abscess pocket that was extended to the membranous septum. The aortic, mitral, and tricuspid mechanical valves were replaced with annular reconstruction without complications. After 14 days of intravenous antibiotics, we successfully changed the epicardial pacemaker into a transvenous DDD-type permanent pacemaker by placing a left ventricular lead via the coronary sinus and an atrial lead in the right atrium appendage. The patient was discharged in a tolerable state and was examined uneventfully in our hospital's outpatient clinic for 8 months.

• 융합정보논문지
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• 제8권6호
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• pp.93-99
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• 2018

본 연구는 대학생을 대상으로 지연성근육통 유발 후 수동적 스트레칭의 효과를 확인하고 부상 시 효과적인 통증완화 및 예방을 위한 재활 운동프로그램을 제안하고자 한다. 연구대상자는 20대 남자 대학생을 대상으로 수동적 스트레칭그룹과 통제그룹으로 구분하였다. 수동적 스트레칭 그룹은 지연성근육통 유발 후 수동적 스트레칭을 실시하였으며 통제그룹은 지연성근육통 유발 후 어떠한 처치도 실시하지 않았다. 지연성근육통 유발 방법은 벤치 스텝 운동을 통하여 유발하였으며, 스텝박스의 높이는 50cm이며, 착지 시 왼쪽 하지 쪽으로 착지하도록 하였다. 측정변인은 혈중피로물질과 주관적 통증척도를 알아보았으며 자료처리는 수동적 스트레칭 그룹과 통제그룹의 비교를 위하여 2-way RGRM ANOVA를 실시하였다. 결론적으로 지연성근육통 유발 후 수동적 스트레칭이 혈중피로물질(CRP, LDH)과 주관적 통증척도(VAS)에 긍정적 효과가 있는 것으로 나타났다.

• 대한의용생체공학회:의공학회지
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• 제40권2호
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• pp.68-74
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• 2019

Lateral epicondylitis is caused by repeated use of the wrist, which causes inflammation and pain in the wrist extensor and tendon of the humerus. Delayed onset muscle soreness (DOMS) caused by repetitive resistance exercise affects the tendons connected in series with the muscle, leading to lateral epicondylitis. Although micro-current stimulation has been suggested as a possible treatment for tendinitis, there are insufficient studies on specific variables such as frequency. In this study, 15 healthy adult males and females developed DOMS in the wrist extensor and tendon in the humerus. The experimental group consisted of a low frequency group applying 20 Hz and a high frequency group applying 100 Hz according to the micro-current frequency. Each subject underwent an experiment for 5 days after DOMS, and the recovery rates were compared by measuring AROM, GPT, MST, PPT, and VAS. As a result, the 20 Hz group showed significant changes in AROM, MST, and VAS compared to the control group on the 4th day, and the recovery rate was also higher than that of the 100 Hz group. On the 5th day, recovery rate of 100 Hz group was higher than 20 Hz in AROM and PPT, and MST showed higher recovery rate than 20 Hz group, but there was no significant difference. These results indicate that microcurrent stimulation is effective for the treatment of delayed myalgia and tendon inflammation and that the 100 Hz group has faster recovery than the 20 Hz group.