• Title/Summary/Keyword: Multivariate statistical analyses

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Statistical Studies on the Formularies of Oriental Medicine(II) -Statistical Analyses of Ginseng Prescription- (한방 처방의 통계적 연구( II ) -인삼배합 한방처방의 통계적 연구-)

  • Hong, Moon-Wha
    • Korean Journal of Pharmacognosy
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    • v.3 no.4
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    • pp.187-197
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    • 1972
  • In spite of the fact that the system of oriental medicine still remains in the realm of 'unproven-method of treatment', no one can deny that the oriental medicine is a rich source of idea and motivation for the discovery of new drug from natural sources. However, non-scientific, mystic hypothetical system of oriental medicine refuses to be revealed scientifically. For the purpose of drawing useful parameters for inductive reasoning of the system, a new approach which comprises statistical analyses of prescription was attempted in this study. One hundred and thirty two ginseng-compounds prescription in 'Bang-Yak-Hap-Pyon', one of the most popular formularies of oriental medicine in Korea, were analysed by multivariate analysis technique. The results revealed ginseng from many points of view, e.g., therapeutic indications, dose, and compatibility, etc. Among these, the most striking coincidence with scientific achievements of modern pharmacology, is the fact that the oriental medicine has characterized ginseng already from remote ancient times as neither a specific curative nor an aphrodisiac, but a non-specific adaptogenic drug for general infirmity.

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Comparison of Variability in SCA Maps Using the Procrustes Analysis

  • Yun, Woo-Jung;Choi, Yong-Seok
    • Proceedings of the Korean Statistical Society Conference
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    • 2003.05a
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    • pp.163-165
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    • 2003
  • Some multivariate analyses provide configurations for variables or objects in low dimensional space because we can see easily their relation. In particular, in simple correspondence analysis(SCA), we can obtain the various configurations which are called SCA Maps based on the algebraic algorithms. Moreover, it often occur the variability among them. Therefore, in this study, we will give a comparison of variability of SCA maps using the procrustes analysis which is a technique of comparing configurations in multidimensional scaling.

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Detection of Hotspots on Multivariate Spatial Data

  • Moon, Sung-Ho
    • Journal of the Korean Data and Information Science Society
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    • v.17 no.4
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    • pp.1181-1190
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    • 2006
  • Statistical analyses for spatial data are important features for various types of fields. Spatial data are taken at specific locations or within specific regions and their relative positions are recorded. Lattice data are synoptic observation covering an entire spatial region, like cancer rates corresponding to each county in a state. Until now, the echelon analysis has been applied only to univariate spatial data. As a result, it is impossible to detect the hotspots on the multivariate spatial data In this paper, we expand the spatial data to time series structure. And then we analyze them on the time space and detect the hotspots. Echelon dendrogram has been made by piling up each multivariate spatial data to bring time spatial data. We perform the structural analysis of temporal spatial data.

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THE USE OF MULTIVARIATE STATISTICS TO EVALUATE THE RESPONSE OF RICE STRAW VARIETIES TO CHEMICAL TREATMENT

  • Vadiveloo, J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.9 no.1
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    • pp.83-89
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    • 1996
  • Multivariate statistical procedures were used to analyse data on the chemical composition and in vitro digestibility of four varienties of rice straw after treatment with 4% NaOH solution, 4% urea solution or distilled water (control) for 48 hours. For each treatment, stepwise discriminant analysis identified the variables which maximized differences between varieties and the eigenvectors from principal component analysis quantified the contribution of these criterion variables to varietal differences. The overall response of varieties to chemical treatment was demonstrated qualitatively, by cluster analysis, and quantitatively, from the magnitude of the principal component scores. The analysis revealed that the urea and control treatments elicited the same response whereas NaOH had the greatest effect on the poorest straw variety. Similar analyses conducted on the botanical fractions of the varieties showed that the relative response of the inflorescence, stem, leaf blade and leaf sheath fractions was not altered by chemical treatment.

Local Projective Display of Multivariate Numerical Data

  • Huh, Myung-Hoe;Lee, Yong-Goo
    • The Korean Journal of Applied Statistics
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    • v.25 no.4
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    • pp.661-668
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    • 2012
  • For displaying multivariate numerical data on a 2D plane by the projection, principal components biplot and the GGobi are two main tools of data visualization. The biplot is very useful for capturing the global shape of the dataset, by representing $n$ observations and $p$ variables simultaneously on a single graph. The GGobi shows a dynamic movie of the images of $n$ observations projected onto a sequence of unit vectors floating on the $p$-dimensional sphere. Even though these two methods are certainly very valuable, there are drawbacks. The biplot is too condensed to describe the detailed parts of the data, and the GGobi is too burdensome for ordinary data analyses. In this paper, "the local projective display(LPD)" is proposed for visualizing multivariate numerical data. Main steps of the LDP are 1) $k$-means clustering of the data into $k$ subsets, 2) drawing $k$ principal components biplots of individual subsets, and 3) sequencing $k$ plots by Hurley's (2004) endlink algorithm for cognitive continuity.

Development of Real-Time Water Quality Abnormality Warning System for Using Multivariate Statistical Method (다변량 통계기법을 활용한 실시간 수질이상 유무 판단 시스템 개발)

  • Heo, Tae-Young;Jeon, Hang-Bae;Park, Sang-Min;Lee, Young-Joo
    • Journal of Korean Society of Environmental Engineers
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    • v.37 no.3
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    • pp.137-144
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    • 2015
  • The purpose of this study is to develop an warning system to detect real-time water quality abnormality using a multivariate statistical approach. In this study, we applied principal component analysis among multivariate data analyses which was used for the correlation between water quality parameters considering the real-time algorithm to determine abnormality in water quality. We applied our approach to real field data and showed the utilization of algorithm for the real-time monitoring to find water quality abnormality. In addition, our approach with Korea Meterological Adminstration database identified heavy rain data due to climate change is one of the most important factors to explain water quality abnormality.

Comparative Analysis of Cultivation Region of Angelica gigas Using a GC-MS-Based Metabolomics Approach (GC-MS 기반 대사체학 기술을 응용한 참당귀의 산지비교분석)

  • Jiang, Guibao;Leem, Jae Yoon
    • Korean Journal of Medicinal Crop Science
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    • v.24 no.2
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    • pp.93-100
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    • 2016
  • Background: A set of logical criteria that can accurately identify and verify the cultivation region of raw materials is a critical tool for the scientific management of traditional herbal medicine. Methods and Results: Volatile compounds were obtained from 19 and 32 samples of Angelica gigas Nakai cultivated in Korea and China, respectively, by using steam distillation extraction. The metabolites were identified using GC/MS by querying against the NIST reference library. Data binning was performed to normalize the number of variables used in statistical analysis. Multivariate statistical analyses, such as Principal Component Analysis (PCA), Partial Least Squares-Discriminant Analysis (PLS-DA), and Orthogonal Partial Least Squares-Discriminant Analysis (OPLS-DA) were performed using the SIMCA-P software. Significant variables with a Variable Importance in the Projection (VIP) score higher than 1.0 as obtained through OPLS-DA and those that resulted in p-values less than 0.05 through one-way ANOVA were selected to verify the marker compounds. Among the 19 variables extracted, styrene, ${\alpha}$-pinene, and ${\beta}$-terpinene were selected as markers to indicate the origin of A. gigas. Conclusions: The statistical model developed was suitable for determination of the geographical origin of A. gigas. The cultivation regions of six Korean and eight Chinese A. gigas. samples were predicted using the established OPLS-DA model and it was confirmed that 13 of the 14 samples were accurately classified.

Prediction of High Level Ozone Concentration in Seoul by Using Multivariate Statistical Analyses (다변량 통계분석을 이용한 서울시 고농도 오존의 예측에 관한 연구)

  • 허정숙;김동술
    • Journal of Korean Society for Atmospheric Environment
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    • v.9 no.3
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    • pp.207-215
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    • 1993
  • In order to statistically predict $O_3$ levels in Seoul, the study used the TMS (telemeted air monitoring system) data from the Department of Environment, which have monitored at 20 sites in 1989 and 1990. Each data in each site was characterized by 6 major criteria pollutants ($SO_2, TSP, CO, NO_2, THC, and O_3$) and 2 meteorological parameters, such as wind speed and wind direction. To select proper variables and to determine each pollutant's behavior, univariate statistical analyses were extensively studied in the beginning, and then various applied statistical techniques like cluster analysis, regression analysis, and expert system have been intensively examined. For the initial study of high level $O_3$ prediction, the raw data set in each site was separated into 2 group based on 60 ppb $O_3$ level. A hierarchical cluster analysis was applied to classify the group based on 60 ppb $O_3$ into small calsses. Each class in each site has its own pattern. Next, multiple regression for each class was repeatedly applied to determine an $O_3$ prediction submodel and to determine outliers in each class based on a certain level of standardized redisual. Thus, a prediction submodel for each homogeneous class could be obtained. The study was extended to model $O_3$ prediction for both on-time basis and 1-hr after basis. Finally, an expect system was used to build a unified classification rule based on examples of the homogenous classes for all of sites. Thus, a concept of high level $O_3$ prediction model was developed for one of $O_3$ alert systems.

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Complex sample design effects and inference for Korea National Health and Nutrition Examination Survey data (국민건강영양조사 자료의 복합표본설계효과와 통계적 추론)

  • Chung, Chin-Eun
    • Journal of Nutrition and Health
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    • v.45 no.6
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    • pp.600-612
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    • 2012
  • Nutritional researchers world-wide are using large-scale sample survey methods to study nutritional health epidemiology and services utilization in general, non-clinical populations. This article provides a review of important statistical methods and software that apply to descriptive and multivariate analysis of data collected in sample surveys, such as national health and nutrition examination survey. A comparative data analysis of the Korea National Health and Nutrition Examination Survey (KNHANES) was used to illustrate analytical procedures and design effects for survey estimates of population statistics, model parameters, and test statistics. This article focused on the following points, method of approach to analyze of the sample survey data, right software tools available to perform these analyses, and correct survey analysis methods important to interpretation of survey data. It addresses the question of approaches to analysis of complex sample survey data. The latest developments in software tools for analysis of complex sample survey data are covered, and empirical examples are presented that illustrate the impact of survey sample design effects on the parameter estimates, test statistics, and significance probabilities (p values) for univariate and multivariate analyses.