• 제목/요약/키워드: Multiplexed detection

검색결과 45건 처리시간 0.034초

Magnetic Force-based Immunochip using Superparamagnetic Nanoparticles

  • Park, Je-Kyun;Kim, Kyu-Sung
    • 한국생물공학회:학술대회논문집
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    • 한국생물공학회 2005년도 생물공학의 동향(XVI)
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    • pp.19-19
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    • 2005
  • This paper reports a novel magnetic force-based microfluidic immunoassay using microbeads and magnetic nanoparticles. The magnetic force-based immunoassay was devised first and successfully applied to detect the rabbit IgG as the model analyte of microfluidic sandwich immunoassay. The microchannels were fabricated by poly(dimethysiloxane) (PDMS) molding processes and bonded on a slide glass by plasma treatment. At the part of the inlet, sample solution was hydrodynamically focused. The focused microbeads of sample solution were flowed through the 150 ${\mu}m$ width channel of outlet. However, when the microbeads are conjugated with the superparamagnetic nanoparticles under the applied magnetic fields, they will switch their flow path and flow through the 95 ${\mu}m$ width channel of outlet. The movements of microbeads conjugated with magnetic nanoparticles were demonstrated by magnetic field $gradients.^{1)}$ High magnetic field gradients using micro electromagnets could be applied to this detection method for high sensitivity and lower detection limit. In addition, the multiplexed $immunoassay^{2)}$ using an encoded microbead which is immobilized with a certain antibody could be possible using this detection principle.

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A Signal Detection Method based on the Double Detection for Spatially Multiplexed MIMO Systems (다중 안테나 시스템을 위한 이중 검출 기반의 신호검출 기법)

  • Kim, Jung-Hyun;Bahng, Seung-Jae;Park, Youn-Ok
    • The Journal of Korean Institute of Communications and Information Sciences
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    • 제34권6C호
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    • pp.634-641
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    • 2009
  • The goal of OSIC-series detection methods is to approach the ML performance with feasible complexity. However, since they sometimes suffer from the empty vector problem, they can not achieve the soft-output ML performance or many candidate vectors are required to achieve the soft-output ML performance. In this paper, we propose the novel detection method, which can generate the reliable soft-outputs without suffering from empty vector problem. The proposed detector can approach the near soft-output ML performance as well as hard-output. Further, the complexity study shows that the proposed detection method has the lowest complexity compared to the other detectors having the near ML performance.

A Novel Fixed-Complexity Signal Detection Technique Using Lattice Reduction for Multiple Antenna Systems (다중 안테나 시스템을 위한 고정된 연산 복잡도를 갖는 격자 감소 기반 신호 검출 기법)

  • Yang, Yusik;Suh, Dong Geun;Kim, Jaekwon
    • The Journal of Korean Institute of Communications and Information Sciences
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    • 제38A권1호
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    • pp.10-18
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    • 2013
  • Recently, a fixed complexity LR(fcLR) technique was proposed. Also QR-LRL signal detection method was proposed in which all constellation symbols are tried as the symbol corresponding to the least reliable layer (LRL), thereby achieving high error performance. In this paper, we combine these two efficient methods to propose a novel detection method. When the LRL is disregarded in the process of LR, the worst case complexity of LR is significantly reduced. Also, the proposed method is shown to be superior to the conventional fcLR-based detection method from the perspective of error performance. Simulations are performed to demonstrate the efficacy of the proposed method.

An Improved Ordering Method for MIMO Signal Detection Using QR Decomposition and Successive Interference Cancellation (QR 분해 및 순차적 간섭제거 기반의 MIMO 신호검출 기법을 위한 향상된 순서화 방법)

  • Bak, Sang-Hyun;Kim, Jae-Kwon;Yang, Won-Young
    • The Journal of Korean Institute of Communications and Information Sciences
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    • 제34권10C호
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    • pp.1010-1015
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    • 2009
  • In this paper, we propose a novel detection ordering technique for MIMO signal detection methods based on QR decomposition and successive interference cancellation (SIC). Recently, new signal detection methods for spatially multiplexed (SM) MIMO systems were proposed, where all the constellation points are tried as the first layer symbol, and the remaining layer symbols are estimated via SIC, producing candidate vectors. Finally, the ML metric values are calculated for the candidate vectors, that are again used to select the best symbol vector. It was also shown that the ordering method in the conventional V-BLAST is not suitable to these signal detection methods. In this paper, we propose a novel ordering method, and we show via computer simulations that the proposed ordering method improves the error performance.

Conceptual design and preliminary characterization of serial array system of high-resolution MEMS accelerometers with embedded optical detection

  • Perez, Maximilian;Shkel, Andrei
    • Smart Structures and Systems
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    • 제1권1호
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    • pp.63-82
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    • 2005
  • This paper introduces a technology for robust and low maintenance cost sensor network capable to detect accelerations below a micro-g in a wide frequency bandwidth (above 1,000 Hz). Sensor networks with such performance are critical for navigation, seismology, acoustic sensing, and for the health monitoring of civil structures. The approach is based on the fabrication of an array of high sensitivity accelerometers, each utilizing Fabry-Perot cavity with wavelength-dependent reflectivity to allow embedded optical detection and serialization. The unique feature of the approach is that no local power source is required for each individual sensor. Instead one global light source is used, providing an input optical signal which propagates through an optical fiber network from sensor-to-sensor. The information from each sensor is embedded onto the transmitted light as an intrinsic wavelength division multiplexed signal. This optical "rainbow" of data is then assessed providing real-time sensing information from each sensor node in the network. This paper introduces the Fabry-Perot based accelerometer and examines its critical features, including the effects of imperfections and resolution estimates. It then presents serialization techniques for the creation of systems of arrayed sensors and examines the effects of serialization on sensor response. Finally, a fabrication process is proposed to create test structures for the critical components of the device, which are dynamically characterized.

Multi-modal Wearable Device for Cardiac Arrest Detection (심정지 감지를 위한 다생체 신호 측정 웨어러블 디바이스 개발)

  • Ahn, Hyun Jun;You, Sung Min;Cho, Kyeongwon;Park, Hoon Ki;Kim, In Young
    • Journal of Biomedical Engineering Research
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    • 제38권6호
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    • pp.330-335
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    • 2017
  • Cardiac arrest is owing to the failure of the heart that makes the blood circulation stop. Arrested blood circulation prevents the supply of the oxygen and the glucose and it results the loss of consciousness and, finally, brain death. Many public institution installed the AED for emergency treatment, but, it is not efficient when the patient is alone. In this paper, we made multiplexed wearable device for cardiac arrest detection. With this device, we measure the individual's electrocardiography, heart sound and motion. If the cardiac arrest is detected, the device make a warning horn and transmit the signal for defibrillation. We obtain 98.33% of ECG data, 94.5% of PCG data and 98.38% of IMU data accuracy for each evaluation and 93.33% accuracy for integrated evaluation.

A Multi-purpose Fingerprint Readout Circuit Embedding Physiological Signal Detection

  • Eom, Won-Jin;Kim, Sung-Woo;Park, Kyeonghwan;Bien, Franklin;Kim, Jae Joon
    • JSTS:Journal of Semiconductor Technology and Science
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    • 제16권6호
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    • pp.793-799
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    • 2016
  • A multi-purpose sensor interface that provides dual-mode operation of fingerprint sensing and physiological signal detection is presented. The dual-mode sensing capability is achieved by utilizing inter-pixel shielding patterns as capacitive amplifier's input electrodes. A prototype readout circuit including a fingerprint panel for feasibility verification was fabricated in a $0.18{\mu}m$ CMOS process. A single-channel readout circuit was implemented and multiplexed to scan two-dimensional fingerprint pixels, where adaptive calibration capability against pixel-capacitance variations was also implemented. Feasibility of the proposed multi-purpose interface was experimentally verified keeping low-power consumption less than 1.9 mW under a 3.3 V supply.

An Efficient Soft-Output MIMO Detection Method Based on a Multiple-Channel-Ordering Technique

  • Im, Tae-Ho;Park, In-Soo;Yoo, Hyun-Jong;Yu, Sung-Wook;Cho, Yong-Soo
    • ETRI Journal
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    • 제33권5호
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    • pp.661-669
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    • 2011
  • In this paper, we propose an efficient soft-output signal detection method for spatially multiplexed multiple-input multiple-output (MIMO) systems. The proposed method is based on the ordered successive interference cancellation (OSIC) algorithm, but it significantly improves the performance of the original OSIC algorithm by solving the error propagation problem. The proposed method combines this enhanced OSIC algorithm with a multiple-channel-ordering technique in a very efficient way. As a result, the log likelihood ratio values can be computed by using a very small set of candidate symbol vectors. The proposed method has been synthesized with a 0.13-${\mu}m$ CMOS technology for a $4{\times}4$ 16-QAM MIMO system. The simulation and implementation results show that the proposed detector provides a very good solution in terms of performance and hardware complexity.

New Developments for Mosaic CCDs

  • Han, Wonyong
    • Bulletin of the Korean Space Science Society
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    • 한국우주과학회 1993년도 한국우주과학회보 제2권2호
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    • pp.21-21
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    • 1993
  • The imaging areas of currently available optical detectors are relatively small to cope with large image areas such as telescope focal Planes. One Possibility to obtain large detection areas is to assemble mosaics of Charge Coupled Devices(CCDs) and drive them simultaneously. Parallel driving of many CCDs together rules out the possibility of individual tuning; however such optimisation is very important when the ultimate low light level performance is required particularly for new devices. In this work, a new concept has been developed for an entirely novel approach where the drive waveforms are multiplexed and interleaved. This simultaneously reduces the number of leadout connections and permits individual optimisation efficiently. The controller has been designed to include one electronic of component produced by CAD software where most of the digital circuits are integrated to minimise the component count and improve the efficiency of the system greatly. The software has an open architecture to permit convenient modificationl by the user to fit their specific purposes. The desire of controller allows great flexibility of system parameters by the softwa re, specifically for the compatibility to deal with any number of mixed CCDs and in any format within the practical limit. The system has been integrated to test the performance and the result is discussed for readout noise, system linearity and cross-talk between the CCDs. The system developed in this work can be applicable not only for astro nomical observation with a telescope but also in other related fields for low light level detection systems such as spectroscopic application, remote sensing and X-ray detecti13n systems with large sensing areas and high resolution.

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Characteristics of Compensation for Distorted Optical Pulse with Initial Frequency Chirp in 3 X 40 Gbps WDM Systems Adopted Mid-Span Spectral Inversion

  • Lee, Seong-Real;Lee, Yun-Hyun
    • Journal of electromagnetic engineering and science
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    • 제3권2호
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    • pp.79-85
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    • 2003
  • In this paper, we investigated the degree of compensation for distorted optical pulse of wavelength division multiplexed(WDM) channel with initial frequency chirp generated in optical transmitter. The WDM channel signal distortion is due to chromatic dispersion, self phase modulation(SPM) and cross phase modulation(XPM) in fiber. The considered system is 3 ${\times}$ 40 Gbps intensity modulation direct detection(IM/DD) WDM transmission systems, which adopted mid-span spectral inversion(MSSI) as compensation method. We confirmed that the effect of initial frequency chirp on compensation for signal distortion due to a SPM is gradually decreased as a dispersion coefficient of fiber becomes gradually small. But, in the aspect of a compensation for signal distortion due to both SPM and XPM, the effect of initial frequency chirp on compensation is gradually decreased as a dispersion coefficient of fiber becomes gradually large.