• Strategy21
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• 통권44호
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• pp.377-416
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• 2018

The purpose of this study is to investigate the effects of the job stresses perceived by R.O.K. naval crews on turnover intentions and job satisfactions. Especially, this study aims to derive the policy implication for the trait characteristics by comparing the job attitude between the surface naval ship and submarine crew. For this purpose, we surveyed 1,000 naval crews. Then, multiple regression analysis was performed. Next, a T-test was conducted to test statistical significance of group differences. First, the job stresses perceived by naval crews were higher in the order of physical environments, overworks, compensation incompetence, lacks of autonomy, and conflicts with people. Second, the job stresses perceived by submarine crews were higher than that of surface naval ship crews. It was also proved statistically significant by the T-test. Third, the physical environments, lacks of autonomy, conflicts of relativity, and inadequate compensation stress have a positive statistically significant effect on turnover intentions of naval crews. Fourth, lacks of autonomy, conflicts of relativity, and inadequate compensation factors have a statistically significant negative effect on the job satisfactions of naval crews. Finally, multiple regression analysis was performed between the independent and dependent variables of the naval crews, and the policy implications were derived.

• Journal of Chest Surgery
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• 제16권3호
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• pp.362-367
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• 1983

Pulmonary arteriovenous fistula is a congenital malformation resulting from errant capillary development, with incomplete formation or disintegration of the vascular septa that normally divide the primitive connections between the venous and arterial plexuses. It generally occurs as part of the disorder known as hereditary hemorrhagic telangiectasia [Rendu-Osler-Weber disease]. The hereditary lesion is transmitted as a simple non-sex-linked dominant trait. It may be single or multiple, too small to see on plain chest films or large and easily recognized. One third of the lesions are multiple on plain chest film. The pathogenesis of its symptoms is that unoxygenated, desaturated arterial blood enters into the pulmonary venous system, directly. Recently we have experienced a case of the pulmonary arteriovenous fistula in 26 years old male soldier, which was confirmed by pulmonary angiography preoperatively. 2 thumb-tip sized, well circumscribed cystic masses filled with bright red colored blood were seen in subpleural and anterolateral portion of the right upper lobe. Right upper Iobectomy was performed due to close approximation of the fistula with pulmonary vein. Microscopically, it shows angiomatous dilatation of the abnormal vessels embedding in the parenchyma. Postoperative physiologic studies show nearly normal arterial oxygen saturation, hemoglobin and RBC count. There was good, uneventful postoperative course.

• 대한간호학회지
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• 제9권1호
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• pp.9-22
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• 1979

The major purpose of this study was to compare the state anxiety of surgical patients by sex (male/female), area of operation (sex-organ/non sex-organ), and family planning (having the plan of child-bearing/having no plan of child-bearing). One hundred sixty patients who were to get surgical operation were equally divided into eight groups resulted from combination of variables of sex, area of operation, and family planning, The state anxiety of surgical patients was measured in terms of the discrepancy score between the state anxiety score on the State-Trait Anxiety Inventory (STAI) administered at a day before operation and the trait anxiety score on it which was administered at a day before discharge. In order to test statistically the differences among meant scores of the state anxiety obtained by eight groups, multiple comparisons were carried out by Scheffe method. The results of this study led to the conclusions that, (1) there was no significant sex difference in the state anxiety of surgical patients, when the area of operation and the family planning variables were disregarded, (2) the state anxiety of patients who were to get operation of their sex-organ was significantly higher than that of patients who were to get operation on the parts other than their sex-organ, when variables of the sex and the family planning were not taken into account, (3) there was no significant sex difference in the state anxiety of patients who were to Bet operation on the parts other than their sex-organ, when the family planning variable was disregarded, (4) the state anxiety of female patients who were to get operation on their sex-organ was significantly higher than the stale anxiety of male patients who were to get operation on their sex-organ, when the family planning variable was not taken into account.

• 생물정신의학
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• 제18권4호
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• pp.245-253
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• 2011

Objectives In the current study, we quantitatively estimated changes in appetite and eating behavior of bipolar disorder patients during the pharmacotherapy. We also investigated their contribution to the weight gain and their association with specific food-craving characteristics of the patients. Methods Subjects included forty-one bipolar disorder patients and fifty-six controls. Currently sustained natures of food craving were assessed using the General-Food Craving Questionnaire-Trait (G-FCQ-T) and changes in appetite and eating behavior were measured using the Drug-Related Eating Behavior Questionnaire (DR-EBQ). Results Compared to the control group, the patients' group showed significantly higher body mass index (t=2.028, p=0.045). The patients' group had significantly higher 'Preoccupation with food' factor score of G-FCQ-T (p=0.016) than that of the control group. Hierarchical multiple regression analysis showed that only 'preoccupation with food' factor independently predicted psychotropic medication-induced appetite change. Conclusions Appetite change while receiving psychotropic medication seems to be related to the weight-gain and associated with craving natures of 'preoccupation with food' in bipolar disorder. Appetite and/or eating behavioral changes measured by G-FCQ-T and DR-EBQ could be regarded as an important mediating factor in future studies exploring biological mechanisms of weight gain related with pharmacotherapy for bipolar disorder.

• 산업경영시스템학회지
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• 제40권3호
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• pp.107-115
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• 2017

The purpose of this study is to find and compare the differences in stress level, stressor, and coping style of high school students according to their personality traits. And to identify the personality traits contributing to stress reduction. The results of the study can be used as basic data for reducing the stress of adolescents to improve their academic achievement and maintain mental and physical stability. The questionnaire survey was conducted for 10 days from June 7 to June 16, 2017 for S high school students in Chungbuk Province. The study employed four measuring instruments as Ego-gram, Ok-gram, stressor scale, and stress coping type scale. Individual personality traits were classified into ego-states and ok-states in TA (Transactional Analysis). Stressors are classified into 5 categories (school life, home life, human relationship, myself, environment) and stress coping styles are classified into 4 categories (problem-focused coping, social-support coping, feeling-focused coping, hope-thinking coping) used in the previous studies. The collected data were analyzed using T-test, ANOVA, and multiple regression analysis. As a result, the stress level of high school students showed significant differences according to sex, year, grade, sleeping time, personality traits, and coping styles. Personality traits that contributed to the stress increase were NP, AC, 'you positive', 'i negative' and personality trait that contributes to stress reduction is 'you negative.' Therefore, we can judge that individual personality traits have significant effects on stress level, stressor, and coping style and need to find the effective stress management method suitable for individual personality traits using counseling, repetition training, self-suggestion etc.

• Genomics & Informatics
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• 제12권4호
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• pp.187-194
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• 2014

Metabolic syndrome (METS) is a disorder of energy utilization and storage and increases the risk of developing cardiovascular disease and diabetes. To identify the genetic risk factors of METS, we carried out a genome-wide association study (GWAS) for 2,657 cases and 5,917 controls in Korean populations. As a result, we could identify 2 single nucleotide polymorphisms (SNPs) with genome-wide significance level p-values (< $5{\times}10^{-8}$), 8 SNPs with genome-wide suggestive p-values ($5{\times}10^{-8}{\leq}$ p < $1{\times}10^{-5}$), and 2 SNPs of more functional variants with borderline p-values ($5{\times}10^{-5}{\leq}$ p < $1{\times}10^{-4}$). On the other hand, the multiple correction criteria of conventional GWASs exclude false-positive loci, but simultaneously, they discard many true-positive loci. To reconsider the discarded true-positive loci, we attempted to include the functional variants (nonsynonymous SNPs [nsSNPs] and expression quantitative trait loci [eQTL]) among the top 5,000 SNPs based on the proportion of phenotypic variance explained by genotypic variance. In total, 159 eQTLs and 18 nsSNPs were presented in the top 5,000 SNPs. Although they should be replicated in other independent populations, 6 eQTLs and 2 nsSNP loci were located in the molecular pathways of LPL, APOA5, and CHRM2, which were the significant or suggestive loci in the METS GWAS. Conclusively, our approach using the conventional GWAS, reconsidering functional variants and pathway-based interpretation, suggests a useful method to understand the GWAS results of complex traits and can be expanded in other genomewide association studies.

• International Journal of Industrial Entomology and Biomaterials
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• 제9권2호
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• pp.199-205
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• 2004

With the main objective to know the feasibility of exploitation of F$_1$ hybrids in semi arid and arid climatic conditions of India, the present study was carried out by utilising RD$_1$ as female parent and six bivoltine silkworm breeds viz., CSR$_2$, CSR$_4$, CSR$_{5}$, CSR$_{17}$, CSR$_{18}$ and CSR$_{19}$ along with NB$_4$D$_2$ as male parents. Different hybrids exhibited their superiority for various economic characters during different seasons. Among F$_1$ hybrids, RD$_1$${\times}$CSR$_{5}$ was adjudicated as the best hybrid in terms of expression of significant positive hybrid vigour over mid parental value for five economic characters namely hatching %, cocoon yield, cocoon weight, cocoon shell weight and filament size, highest multiple trait average evaluation index value of 56.77 and comparatively uniform cocoon size with coefficient of variation (CV%) of 3.80 and Standard Deviation (SD) of 7.99 during September - October 2003. Results of the present study revealed that the F$_1$ hybrid RD$_1$${\times}$CSR$_{5}$ can be successfully exploited on commercial in semi arid and arid climatic conditions in India. India.dia.

• 대한불안의학회지
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• 제15권2호
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• pp.122-126
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• 2019

Objective : Dynamic proteolysis, through the ubiquitin-proteasome system, is an important molecular mechanism for the constant regulation of synaptic plasticity and stress responses in humans. In this study, we examined whether genetic variants in the ubiquitin-specific peptidase (USP) genes were associated with psychological traits of resilience and susceptibility to neuropsychiatric disorders for each gender. Methods : A total of 344 Korean healthy youths (190 males, 154 females) were included in the study. A genotyping of rs2241646 of USP2 and rs346006 of USP46 was performed. The Connor-Davidson Resilience Scale and Brief Fear of Negative Evaluation Scale were administered for measuring trait resilience and social anxiety, respectively. The genetic associations of the USP variants were tested using multiple analyses of covariance with psychological traits as dependent variables after controlling for age in each gender. Results : For USP2 rs2241646, women with the TT genotype showed significantly higher resilience and lower social anxiety, as compared to those carrying the C allele. There were no associations between USP46 rs346005 and the psychological traits in both genders. Conclusions : The present study showed a possible genetic association between the USP2 rs2241646 and stress resilience and trait anxiety in women. The findings suggest that ubiquitin-proteasome system may be related to the resilience and susceptibility to stress-related neuropsychiatric disorders such as anxiety disorders, possibly through the regulation of dynamic proteolysis responses to stress.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2022년도 추계학술대회
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• pp.187-187
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• 2022

Purple-discoloration of the uppermost leaves has been observed in some soybean cultivars in recent years. The purpose of this study was to characterize the novel phenotypic changes between the uppermost and middle leaves via multiple approaches. First, quantitative trait loci mapping was conducted to detect loci associated with the novel phenotype using 85 recombinant inbred lines (RILs) of the 'Daepung' × PI 96983 population. 180K SNP data, a major quantitative trait locus (QTL) was identified at around 60 cM of chromosome 6, which accounts for 56% of total phenotypic variance. The genomic interval is about ~700kb, and a list of annotated genes includes the T-gene which is known to control pubescence and seed coat color and is presumed to encode flavonoid 35-hydroxylase (F3'H). Based on Hyperspectral imaging, the reflectance at 528-554 nm wavelength band was extremely reduced in the uppermost leaves compared to the middle (green leaves), which is presumed die to the accumulation of anthocyanins. In addition, purple-discolored leaf tissues were observed and compared to normal leaves using a transmission electronic microscope (TEM). Base on observations of the cell organelles, the purple-discolored uppermost leaves had many pigments formed in the epidermal cells unlike the normal middle leaves, and the cell wall thickness was twice as thick in the discolored leaves. The thickness of the thylakoid layer in the chloroplast the number of starch grains, the size of starch all decreased in the discolored leaves, while the number of plastoglobule and mitochondria increased.

• Journal of Animal Science and Technology
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• 제65권6호
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• pp.1194-1204
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• 2023

Meat quality comprises a set of key traits such as pH, meat color, water-holding capacity, tenderness and marbling. These traits are complex because they are affected by multiple genetic and environmental factors. The aim of this study was to investigate the molecular genetic basis underlying nine meat quality-related traits in a Yorkshire pig population using a genome-wide association study (GWAS) and subsequent biological pathway analysis. In total, 45,926 single nucleotide polymorphism (SNP) markers from 543 pigs were selected for the GWAS after quality control. Data were analyzed using a genome-wide efficient mixed model association (GEMMA) method. This linear mixed model-based approach identified two quantitative trait loci (QTLs) for meat color (b^*) on chromosome 2 (SSC2) and one QTL for shear force on chromosome 8 (SSC8). These QTLs acted additively on the two phenotypes and explained 3.92%-4.57% of the phenotypic variance of the traits of interest. The genes encoding HAUS8 on SSC2 and an lncRNA on SSC8 were identified as positional candidate genes for these QTLs. The results of the biological pathway analysis revealed that positional candidate genes for meat color (b^*) were enriched in pathways related to muscle development, muscle growth, intramuscular adipocyte differentiation, and lipid accumulation in muscle, whereas positional candidate genes for shear force were overrepresented in pathways related to cell growth, cell differentiation, and fatty acids synthesis. Further verification of these identified SNPs and genes in other independent populations could provide valuable information for understanding the variations in pork quality-related traits.