• Title/Summary/Keyword: Multiple regression model

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Clinical and Symptomatic Correlates of Alexithymia in Schizophrenia (정신분열병의 감정표현 불능증과 관련된 임상 및 증상 요인)

  • Lee, Kyung-Ha;Kim, Dae-Ho;Roh, Sung-Won;Nam, Jeong-Hyun
    • Korean Journal of Psychosomatic Medicine
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    • v.13 no.1
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    • pp.32-40
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    • 2005
  • Objectives : This study looked at the symptoms of alexithymia in schizophrenia and their association with clinical variables and schizophrenic symptomatology. Methods Consecutive fifty eight inpatients with DSM-IV diagnoses of schizophrenia completed 26item version of Toronto Alexithymia Scale (TAS), Symptom Checklist-90-Revised(SCL-90-R), and Positive and Negative Syndrome Scale(PANSS). Results : Authors did not find any correlation between scores of PANSS and TAS. However, all the subscale scores of SCL-90-R were significantly correlated with total score of TAS. Also, 'difficulty identifying and deistinguishing between feelings and bodily sensations' and 'difficulty describing feelings' significantly correlated with SCL-90-R subscale scores. 'Reduced daydreaming' had mixed findings and 'externally oriented thinking' did not correlate. Multiple regression model included Global Severity Index of SCL-90-R accounting 28.2% of variance for TAS scores. Conclusion : These findings together with discrepancy in results between objective and subjective tests suggest that alexithymia in schizophrenia may have two constructs, 'difficulty to describe and communicate feelings(state)' and 'externally oriented thinking(trait)' Authors suggest further study needs to confirm construct validity of TAS in this population.

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Affecting Factors of Insulin Resistance in Obese Children and Adolescents (소아 및 청소년 비만증에서 인슐린 저항성에 미치는 요인)

  • Kim, Duk Hee;Eun, Ho Seon;Choi, In Kyung;Kim, Ho Seung;Cha, Bong Soo;Kim, Dong Kee
    • Clinical and Experimental Pediatrics
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    • v.48 no.10
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    • pp.1076-1081
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    • 2005
  • Purpose : Insulin resistance is the most important risk factor linked to the development of impaired glucose tolerance(IGT), diabetes mellitus and cardiovascular diseases in childhood and adolescent obesity, The purpose of this study was to see whether insulin resistance of obese adolescent is higher than that of obese children. and to analyze gender difference and affecting factors of insulin resistance. Methods : Of the 9,837 school children from 5 to 16 tears old, 92 obese children and 187 adolescent, underwent a two-hour oral glucose tolerance test and plasma glucose, insulin, lipid profiles, leptin and high sensitive C-reactive protein(hs-CRP) were measure. Results : Plasma insulin levels of female were higher compared to those of males during oral glucose tolerance test(P<0.05). Four(4.3%) in obese children and twenty five(13.3%) in obese adolescents met the criteria of IGT. Female, leptin, adiponectin and triglyceride concentrations were strongly correlated with homeostatic model assessment insulin-resistance(HOMA-IR) by multiple linear regression analysis(P<0.05). Conclusion : Obese adolescents might have higher insulin concentrations compared to obese children and obese girls higher insulin concentrations than obese boys. Obese boys and children with impaired glucose tolerance have higher insulin concentrations than those with normal glucose tolerance. HOMA-IR was significantly correlated with female, plasma leptin, adiponectin and triglyceride concentrations.

Assessment of Relationship between Fyn-related Kinase Gene Polymorphisms and Overweight/Obesity in Korean Population

  • Jung, Mi-Young;Kim, Bum-Shik;Kim, Youn-Jung;Koh, In-Song;Chung, Joo-Ho
    • The Korean Journal of Physiology and Pharmacology
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    • v.12 no.2
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    • pp.83-87
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    • 2008
  • The fyn-related kinase (FRK) belongs to the tyrosine kinase family of protein kinases. Recent studies have shown that Frk affects pancreatic beta cell number during embryogenesis and promotes beta cell cytotoxic signals in response to streptozotocin. To investigate the genetic association between FRK polymorphisms and the risk of obesity in Korean population, single nucleotide polymorphisms (SNPs) in the FRK gene region were selected and analyzed. The body mass index (BMI) was calculated, and biochemical data (systolic blood pressure, diastolic blood pressure, hemoglobin A1C, triglyceride, total cholesterol, high density lipoprotein, and low density lipoprotein) of blood sample from each subject were also measured. One hundred fifty five healthy control and 204 overweight/obesity subjects were recruited. Genotype frequencies of six SNPs [rs6568920 (+8391G>A), rs3756772 (+56780A>G), rs3798234 (+75687C>T), rs9384970 (+68506G>A), rs1933739 (+72978G>A), and rs9400883 (+75809A>G)] in the FRK gene were determined by Affymetrix Targeted Genotyping Chip data. According to the classification of Korean Society for the Study of Obesity, control (BMI 18 to < 23) and overweight/obesity (BMI$\geq$23) subjects were recruited. For the analysis of genetic data, EM algorithm, SNPStats, Haploview, HapAnalyzer, SNPAnalyzer, and Helixtree programs were used. Multiple logistic regression analysis (codominant, dominant, and recessive models) was performed. Age and gender as covariates were adjusted. For biochemical data, Student's t test was used. The mean value of BMI in the control and overweigh/obesity groups was 21.1${\pm}$1.2 (mean${\pm}$SD) and 25.6${\pm}$2.0, respectively. All biochemical data of the overweight/obesity group were statistically significance, compared with the control group. Among six SNPs, two linkage disequilibrium (LD) blocks were discovered. One block consisted of rs1933739 and rs9400883, and the other comprised rs3756772 and rs3798234. One SNP (rs9384970, +68506G>A) showed an association with overweight/obesity in the codominant model (p=0.03). Interestingly, the AA genotype distribution in the overweight/obesity group (n=7, 3.5%) was higher than those in the control group (n=1, 0.6%), which is not found in either Japanese or Chinese subjects. Therefore, the AA genotype of rs9384970 may be a risk factor for development of obesity in Korean population. The results suggest that FRK may be associated with overweight/obesity in Korean population.

A Comparative Study on the Methods for Weighting the Dimensions of Customer Satisfaction with Importance Perceived by Customers (고객만족도 조사도구의 차원별 가중치 부여방법 비교)

  • Kang, Myunggeun;Cho, Woohyun;Lee, Sunhee;Choi, Kuison;Mooon, Kitae
    • Quality Improvement in Health Care
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    • v.7 no.2
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    • pp.230-242
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    • 2000
  • Background : The measuring instruments for customer satisfaction in hospitals are often composed of some dimensions reflecting the conceptive complexity of them. Then, overall satisfaction would be expected to be equal the 'weighted' sum of scores by dimensions because the importance rated by customers may be different across the dimensions. But the issue of how to weight the dimensions with importance is not yet solved. We examined 3 sets of weighting methods as to make effect on predictive power against overall satisfaction. Methods : We conducted a survey included 483 subjects who had visited or admitted to a university hospital, using the short form questionnaire being developed by The Korean Society of Quality Assurance in Health Care for out-patient and in-patient. By using a multiple linear regression model, we compared among changes of explanatory powers against overall satisfaction as dependent variable after weighting 4 dimensions of the survey questionnaire as independent variables with importance scores of dimensions perceived by consumers. And we compared the feasibility of each weighting, methods by checking missing cases. Results : There were no weighting methods increasing the explanatory power after applying them. The method of absolute scoring was found higher explanatory-power than others, but this finding had no statistical significance. Regarding the number of missing value, method of absolutely scoring had the least cases. Conclusion : Our findings suggested that weighting the dimensions with importance might have little significance in the cases of scales having items highly correlated, such as consumers' satisfaction. Though asking with items to be answered absolutely, customers might be rating relatively in some degree and this method produced least missing cases. Considering these points, in the cases when weighting the dimensions with importance would be required, we suggest that weighting method by absolute scoring might be better than others.

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Analysis of the Influence of Hopelessness, Psychosocial Stress and Depression on Suicide Ideation Among Middle School Students Using the Structural Equation Model (구조방정식모형을 이용한 중학생의 절망감, 사회심리적스트레스 및 우울이 자살생각에 미치는 영향 분석)

  • Bae, Sang-Yun;Cho, Young-Chae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.6
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    • pp.3685-3695
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    • 2014
  • This study was performed to determine the suicide ideation and its association with hopelessness, psychosocial stress and depression among some middle school students. The survey was administered to 975 middle school students in Gyeongin area during the period, May $1^{st}$ to June $30^{th}$, 2013. Structured self-administered questionnaires were delivered and collected without the respondents' personal information. As a result, concerning the correlation of depression with various factors, the level of suicide ideation was positively correlated with hopelessness, psychosocial stress and depression. Multiple linear regression analysis showed that the factors influencing the suicide ideation included sex distinction, experience of alcohol drinking, hobbies and leisure life, subjective health status, grade, school violence experience, hopelessness, psychosocial stress and depression. An analysis of the covariance structure, hopelessness (BHOP) was more influential on the suicide ideation than psychosocial stress (PWI) and depression (CES-D). The study found that higher hopelessness, severe distress and higher depression tends to increase the suicide ideation.

Association between dietary sodium intake and disease burden and mortality in Koreans between 1998 and 2016: The Korea National Health and Nutrition Examination Survey

  • Park, Clara Yongjoo;Jo, Garam;Lee, Juhee;Singh, Gitanjali M.;Lee, Jong-Tae;Shin, Min-Jeong
    • Nutrition Research and Practice
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    • v.14 no.5
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    • pp.501-518
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    • 2020
  • BACKGROUND/OBJECTIVES: Sodium intake is positively associated with blood pressure, which may increase the risk for cardiovascular disease (CVD). Therefore, we assessed the disease burden of CVD attributable to sodium intakes above 2,000 mg/day and prospectively investigated the association between dietary/urinary sodium levels and the risk of all-cause and CVD-mortality using the Korea National Health and Nutrition Examination Survey (KNHNES). SUBJECTS/METHODS: A total of 68,578 and 33,113 participants were included for comparative risk assessment (CRA) analysis and mortality analysis, respectively, and mean follow-up time for mortality was 5.4 years. CRA analysis was used to quantify attributable incidences of stroke, ischemic heart disease (IHD), and deaths attributable to sodium intake between 1998 and 2016. Cox proportional hazard regression model was used to determine the association between sodium intake and all-cause and CVD-mortality. RESULTS: Mean dietary sodium intake decreased over time, reaching 3,647 mg/day in 2016. Similarly, the population attributable fractions of stroke and IHD, and the number of CVD-associated deaths attributable to high sodium intake/excretion also decreased. In terms of association with mortality, when participants were grouped into quartiles (Q) by energy-adjusted sodium intake, those in Q2 had a lower risk of all-cause mortality than those in Q1 with lower intakes. The risk of CVD-associated mortality was higher only in females with high sodium intake in Q4 than those in Q1. CONCLUSIONS: This nationwide data indicates that, in line with previous studies of multiple cohorts, both low and high sodium intakes may be associated with an increased risk of mortality; therefore, the optimal sodium intake for Koreans needs to be revised.

Study on the Donation and Consumer Attitude for the Retail Brand Management (소매 브랜드 관리를 위한 기부 및 소비자 태도에 관한 연구)

  • Ahn, Sungsook;Kim, Yong-Cheol;Kim, Moon-Seop
    • Journal of Distribution Science
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    • v.16 no.4
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    • pp.49-56
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    • 2018
  • Purpose - The purpose of this study is to provide managerial implications for retail brand managers. Specifically, current study divide donation type into direct donation(e.g., corporate philanthropy) and indirect donation(cause-related marketing) and investigate the donation type on the purchase intention. Also, this research intends to provide the mechanism between the donation type on the purchase intention by showing the mediating role of the consumers' perceived warmth. Moreover, the moderating role of the brand type(non-luxury vs. luxury brand) between the donation type, the warmth perception, and the purchase intention will be examined. Research design, data, and methodology - A total of 174 undergraduate students from a university in Korea were recruited and were randomly assigned to the conditions of a 2(donation type: indirect vs. direct) X 2 (brand type: non-luxury vs. luxury) between-subjects design. The hypotheses were tested using SPSS 21.0. Two-way ANOVA and multiple regression analysis were performed. Results - Empirical results showed that the consumers' perceived warmth was higher in the direct donation condition than the indirect donation condition and moreover this influence of the donation type on the perceived warmth was moderated by the brand type. Specifically, the influence of donation type on the perceived warmth was significant only for luxury brand. And there is an interaction effect of donation type and brand type on the purchase intention. More specifically, the purchase intention for luxury brand was higher in the direct donation condition than the indirect donation condition whereas the purchase intention for non-luxury brand was higher in the indirect donation condition than in the direct donation condition. Conclusions - This research contributed to the CSR literature of retail brand management by showing that the influence of the donation type and the brand type on the purchase intention. Moreover, this study enriched CSR literature by introducing Stereotype Content Model and showing the mediating role of the consumers' perceived warmth. Managerially, these results suggested retail brand managers of non-luxury brand and luxury brand how to select an appropriate type of donation and conduct CSR strategies.

The Effect of Social Trust on Risk Perception : Focused on the Seoul Citizens' Perception (사회신뢰가 위험인식에 미치는 효과 : 서울시민의 인식을 중심으로)

  • Lee, Jae-Wan
    • The Journal of the Korea Contents Association
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    • v.18 no.10
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    • pp.518-526
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    • 2018
  • The purpose of this study is to analyze the effect of social trust on risk perception. In other words, I tried to analyze empirically how the generalized trust about other people they have based on subjective perception of Seoul citizens affects the perception of risk factors. First, the risk factors that Seoul citizens face in everyday life are classified into five categories: natural disaster, technical disaster risk, economic risk, social disintegration risk and health risk. Then, the influence of social trust on each of these risk perception was analyzed by multiple regression model. The results show that social trust has a statistically significant negative impact on all types of risk perception. These results imply that social trust makes low-risk assessments of various risk factors around people. The implication of this study is that the responsibility for risk is given to the central and local governments in the modern risk society. In order to prevent effective risk, it is necessary to make efforts to promote social trust through various activities together with efforts to prevent the spread of unfounded risk will be. And trust among people also promotes cooperation in coping with risks, so it is necessary to promote communication and mutual understanding that can build trust among people in their daily life.

Association Metabolic Syndrome with Sarcopenia in Korean Stroke Patients : Korean National Health and Nutrition Examination Survey Data(2008-2011) (뇌졸중 유병자의 대사증후군과 근감소증의 관련성: 국민건강조사(2008년-2011년)자료를 근거로)

  • Choi, Sook-Hee;Kim, Yun-Hee
    • The Journal of the Korea Contents Association
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    • v.18 no.10
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    • pp.165-174
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    • 2018
  • The purpose of this study was to examine the association metabolic syndrome with sarcopenia in Korean stroke patients. We used the Korean National Health and Nutrition Examination Survey data from 2008 to 2011 and enrolled a total of 316 stroke patients older than 40 years. Data were analyzed by Rao-Scott ${\chi}^2-test$, generalized linear model and composite sample multiple logistic regression. The prevalence of sarcopenia was 47.3% in men and 46.3% in women. The prevalence of metabolic syndrome was 50.3% in men and 73.6% in women. After adjusting for age, smoking status, alcohol consumption, exercise, education, income, sroke sequla and stroke duration, men with sarcopenia had increased risk of metabolic syndrome (95% CI: 2.454-18.482, p<.001). This finding can be used to develop evidence-based health promotion program to prevent stroke reccurance for stroke patients.

A study on Convergence Factors Related with Academic Burnout of Students in Health Majors in Studying for TOEIC (보건계열 일부 대학생의 토익학습의 학업소진 영향과 관련된 융복합적 요인 연구)

  • Hong, Soomi;Kim, Seung-Hee;Bae, Sang-Yun
    • Journal of Digital Convergence
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    • v.15 no.6
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    • pp.315-327
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    • 2017
  • This study was carried out to examine the converging factors related to academic burnout in students from health-related majors who are involved in studying for the Test of English for International Communication (TOEIC). Research subjects included 291 randomly selected students from the J-region, who were enrolled in TOEIC classes. Data collection took place from April 3, 2017 to April 14, 2017, using anonymous self-administered questionnaires. The results of a multiple regression analysis in female students showed higher academic burnout pertaining to studying for the TOEIC when sleeping hours, self-worth, self-efficacy, school adaptation resilience, and study immersion were low, and job-seeking stress and test anxiety were high. The explanatory power of this model was 65%. Based on these results, to reduce academic burnout pertaining to studying for the TOEIC in health majors, it is first necessary to increase sleeping hours, self-worth, self-efficacy, school adaptation resilience, and study immersion, and to make efforts to manage self-competence, job-seeking stress, and test anxiety. The results of this study may be used to decrease the academic burnout caused by studying for the TOEIC in health major students and to increase their aptitude for studying English, to cultivate globalized capabilities. Future studies need to conduct an effect analysis on the control and mediation effect that these factors have on academic burnout.