• Title/Summary/Keyword: Multiple comparisons

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Genome-wide Response of Normal WI-38 Human Fibroblast Cells to 1,763 MHz Radiofrequency Radiation

  • Im, Chang-Nim;Kim, Eun-Hye;Park, Ae-Kyung;Park, Woong-Yang
    • Genomics & Informatics
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    • v.8 no.1
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    • pp.28-33
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    • 2010
  • Increased exposure of human to RF fields has raised concerns for its potential adverse effects on our health. To address the biological effects of RF radiation, we used genome wide gene expression as the indicator. We exposed normal WI-38 human fibroblast cells to 1763 MHz mobile phone RF radiation at a specific absorption rate (SAR) of 60 W/kg with an operating cooling system for 24 h. There were no alterations in cell numbers or morphology after RF exposure. Through microarray analysis, we identified no differentially expressed genes (DEGs) at the 0.05 significance level after controlling for multiple testing errors with the Benjaminiochberg false discovery rate (BH FDR) method. Meanwhile, 82 genes were differentially expressed between RF-exposed cells and controls when the significance level was set at 0.01 without correction for multiple comparisons. We found that 24 genes (0.08% of the total genes examined) were changed by more than 1.5-fold on RF exposure. However, significant enrichment of any gene set or pathway was not observed from the functional annotation analysis. From these results, we did not find any evidence that non-thermal RF radiation at a 60-W/kg SAR significantly affects cell proliferation or gene expression in WI-38 cells.

Review of Channel Quality Indicator Estimation Schemes for Multi-User MIMO in 3GPP LTE/LTE-A Systems

  • Abdulhasan, Muntadher Qasim;Salman, Mustafa Ismael;Ng, Chee Kyun;Noordin, Nor Kamariah;Hashim, Shaiful Jahari;Hashim, Fazirulhisham
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.8 no.6
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    • pp.1848-1868
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    • 2014
  • Multiple-in multiple-out (MIMO) in long-term evolution (LTE) is an essential factor in achieving high speed data rates and spectral efficiency. The unexpected growth in data rate demand has pushed researchers to extend the benefits of multi-user MIMO. The multi-user MIMO system can take full advantage of channel conditions by employing efficient adjustment techniques for scheduling, and by assigning different modulation and coding rates. However, one of the critical issues affecting this feature is the appropriate estimation of channel quality indicator (CQI) to manage the allocated resources to users. Therefore, an accurate CQI estimation scheme is required for the multi-user MIMO transmission to obtain significant improvements on spectral efficiency. This paper presents overviews of multi-user MIMO in LTE/LTE-advanced systems. The link adaptation, scheduling process, and different factors that affect the reliability of CQI measurements are discussed. State-of-the-art schemes for the post-processing CQI estimation, and the comparisons of various CQI estimation schemes to support multi-user MIMO are also addressed.

Adaptive Parallel and Iterative QRDM Detection Algorithms based on the Constellation Set Grouping (성상도 집합 그룹핑 기반의 적응형 병렬 및 반복적 QRDM 검출 알고리즘)

  • Mohaisen, Manar;An, Hong-Sun;Chang, Kyung-Hi;Koo, Bon-Tae;Baek, Young-Seok
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.35 no.2A
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    • pp.112-120
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    • 2010
  • In this paper, we propose semi-ML adaptive parallel QRDM (APQRDM) and iterative QRDM (AIQRDM) algorithms based on set grouping. Using the set grouping, the tree-search stage of QRDM algorithm is divided into partial detection phases (PDP). Therefore, when the treesearch stage of QRDM is divided into 4 PDPs, the APQRDM latency is one fourth of that of the QRDM, and the hardware requirements of AIQRDM is approximately one fourth of that of QRDM. Moreover, simulation results show that in $4{\times}4$ system and at Eb/N0 of 12 dB, APQRDM decreases the average computational complexity to approximately 43% of that of the conventional QRDM. Also, at Eb/N0 of 0dB, AIQRDM reduces the computational complexity to about 54% and the average number of metric comparisons to approximately 10% of those required by the conventional QRDM and AQRDM.

Attributes of Social Networking Services : A Classification and Comparison (소셜 네트워크 서비스의 속성 : 분류와 비교)

  • Sohn, Jeong Woong;Kim, Jin Ki
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.41 no.1
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    • pp.24-38
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    • 2018
  • Since a social networking service (SNS) isconsidered as an effective means to communicate and interact with customers, companies are trying to utilize SNS effectively. There is a lack of theory relating to the attributes of SNS. This study aims to investigate the attributes of SNS to classify SNS. Based on the social network theory, and previous studies on internet, blog, homepage, communication attributes, this study proposes the seven attributes to classify SNS: interaction, communication, entertainment, information, sharing, intimacy and connection. A pre-test, a pilot test and a main test are conducted. In the main test, 239 SNS users are participated. Through a factor analysis this study verifies the seven attributes of SNS. An analysis of variance with multiple comparisons of $Scheff{\acute{e}}$ method identifies that three attributes, interaction, communication and connection, are found to play significant roles to differentiate SNS. Looking at the overall mean values of the SNS by attribute, interaction, sharing, entertainment, intimacy and communication were relatively high in Facebook. Facebook showed higher values in attributes of interaction, sharing, entertainment, intimacy and communication. Twitter shows the relatively high scores for information and connection. Regarding interaction, Facebook shows higher scores than Twitter and Cyworld. For connection, Cyworld showed a significantly lower score than Twitter and Facebook. Cyworld was separated from the others in the light of communication. Cyworld is relatively weak in communication as it is limited to the message exchanges. The results will help in identifying major attributes for each SNS and classifying SNS.

THE COMPARISON OF MICROLEAKAGE OF CLASS V COMPOSITE RESIN RESTORATIONS WITH VARIOUS DENTIN BONDING SYSTEMS (5급 와동에서 수종의 상아질 접착제에 따른 미세누출의 비교)

  • Lim, Yeon-Hee;Lee, Hee-Ju;Hur, Bock
    • Restorative Dentistry and Endodontics
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    • v.26 no.2
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    • pp.153-161
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    • 2001
  • The purpose of this study was to evaluate microleakage of six current dentin bonding systems. In this in vitro study, class V cavities were prepared on buccal and lingual surfaces of thirty extracted human molars. Each margin was on enamel and dentin/cementum. Experimental teeth were randomly divided into six groups of 5 each. Group 1 : Scotchbond Multi-Purpose; Group 2 : Single Bond; Group 3 : Prime&Bond NT ; Group 4 : Clearfil Liner Bond 2 ; Group 5 : MAC Bond II ; Group 6 : One-up Bond F. The bonding agent and composite resin were applied to class V cavities according to manufacturer's directions. After thermocycling, the specimens were immersed in 0.5% basic fuchsin dye solution for 6 hours and sectioned longitudinally through the center of the restoration with a low speed diamond saw. The degree of microleakage was measured as the extent of dye penetration under the stereomicroscope at $\times$20. The data were analyzed using one way ANOVA. When significant differences found. multiple comparisons were made using Duncan's Multiple Range Test. The results of this study were as follows: 1. In all groups, leakage value seen at the enamel margin was significantly lower than that seen at the dentin margin(P<0.001). 2. At the enamel margin, none of the dentin bonding systems used in this study showed statistically significant difference in leakage values(P<0.05). 3. At the cementum margin, group 3 showed the highest leakage value, and others were decreased as group 5, 6, 4 in that order, and group 1, 2 showed the lowest leakage value. There was statistically significant difference between group 3 and the other groups except for group 5(P<0.05).

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COMPARISON OF MARGINAL LEAKAGE OF WEDGE-SHAPED CLASS V CAVITY ACCORDING TO RESTORATIVE MATERIALS (쐐기 형태의 5급와동에서 수복재료에 따른 변연 미세누출의 비교)

  • Jang, Hyun-Joo;Lee, Hee-Joo;Hur, Bock
    • Restorative Dentistry and Endodontics
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    • v.25 no.1
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    • pp.56-62
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    • 2000
  • The purpose of this study was to assess the effects of restorative materials on the marginal leakage of wedge-shaped class V cavity. The study was performed in vitro in 25 defect-free permanent, extracted teeth. Wedge-shaped class V cavities were prepared and then the teeth were randomly selected and restored according to the following. Group A : restoration with Tetric Ceram(composite resin) Group B : restoration with Tetric flow(flowable resin) Group C : restoration with Compoglass after acid etching(compomer) Group D : restoration with Compoglass(compomer) Group E : restoration with Fuji II LC improved(resin-modified GIC) After thermocycling, the specimens were immersed in 5% basic fuchsin solution for 6 hours and sectioned longitudinally through the center of the restoration. The degree of marginal leakage was measured as the extent of dye penetration under the stereomicroscope. The data were analysed using one-way ANOVA. When significant differences found, multiple comparisons were made using Duncan's Multiple Range Test. The results were as follows: 1. The occlusal margins of all groups except for Fuji II LC improved showed lesser leakage than gingival margins and there was statistically significant difference(p<0.05). 2. At the occlusal margins, group A, B showed same marginal leakage scores, and others were decreased as group C, D, E in that order. There were statistically significant difference between group A, Band group D, E, group C and group E(p<0.05). 3. At the gingival margins, group B, C showed same marginal leakage scores, and others were decreased as group A, D, E in that order. But there was statistically significant difference between group B, C and group E(p<0.05). 4. In the Compoglass restoration, acid-etching technique was beneficial for marginal sealing ability at all of margins. But there was no statistically significant difference (p>0.05). In the restorations for wedge-shaped class V cavities, resin restoration with acid etching technique is recommended.

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Color changes of ceramic veneers following glazing with respect to their composition

  • Kim, Sung-Joon;Woo, Jae-Man;Jo, Chan Woo;Park, Ju-Hee;Kim, Soo Kyung;Kahm, Se Hoon
    • The Journal of Advanced Prosthodontics
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    • v.11 no.1
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    • pp.16-22
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    • 2019
  • PURPOSE. The purpose of this study was to compare the translucency and color changes of ceramic laminate veneers of different composition following glazing process. MATERIALS AND METHODS. $10mm{\times}10mm$ square specimens of 0.6 mm and 1.0 mm thicknesses were fabricated with IPS e.max Press (EM) and IPS e.max ZirPress (ZP) (n=10 per group). The color coordinates (CIE $L^*$ $a^*$ $b^*$) of the specimens were recorded with a colorimeter before and after glazing. The color changes and translucency parameter (TP) were calculated. For the comparisons with the composition and thicknesses between the 'not glazed' and 'glazed' groups, statistical analyses were done through paired T-test, independent two-sample T-test, and multiple regression analysis using SPSS 18.0 (P<.05). RESULTS. The TP of 0.6 mm EM was higher than that of 0.6 mm ZP. Total color difference (${\Delta}E^*$) between bare and glazed specimens of 1.0 mm EM was greater than that of 1.0 mm ZP with statistical significance. Following glazing, specimens from all groups showed statistically significant amount of decrease in $L^*$ and $a^*$, and statistically significant increase in $b^*$. The result of multiple regression analysis of EM and ZP showed that ${\Delta}L^*$ improved ${\Delta}E^*$. CONCLUSION. Within the limitations of present study, we conclude that translucency and color of ceramic laminate veneers change significantly after glazing process, and the nature and amount of changes vary with different compositions.

Assessment of pharyngeal airway in Korean adolescents according to skeletal pattern, sex, and cervical vertebral maturation: A cross-sectional CBCT study

  • Elagib, Tassneem;Kyung, Hee-Moon;Hung, Bui Quang;Hong, Mihee
    • The korean journal of orthodontics
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    • v.52 no.5
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    • pp.345-353
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    • 2022
  • Objective: To investigate airway volumes using cone-beam computed tomography (CBCT) by skeletal patterns, sex, and cervical vertebral maturation (CVM) stages in Korean adolescents. Methods: The sample consisted of pretreatment CBCT and cephalograms of 95 adolescents (aged 12-19) obtained out of 1,611 patients examined for orthodontic treatment from 2018 to 2020 in Kyungpook National University Dental Hospital. The samples were classified into two sex groups; three skeletal pattern groups, four chronological age groups and four CVM stages. Nasopharyngeal volumes (NPV), oropharyngeal volumes (OPV), total pharyngeal airway volume (TAV) and minimum cross-sectional area (MCA) measurements were taken from the CBCT. Multiple linear regression analyses to find out which one of the independent variables are good predictors for airway variables. Significant factors were analyzed by two-way multivariate analysis of variance (MANOVA) then multiple comparisons were analyzed using a t-test, and Fisher least significant difference. Results: Age, sex, CVM, and Sella-Nasion-B point have significant influence on airway variable. Males and females showed similar patterns of change in chronological age groups 1-3; however, males had larger NPV, OPV, and MCA at CVM in group 4. According to CVM stages, males had larger OPV, TAV, and MCA at CVM stage 6 (p-value: 0.019, 0.021, 0.015, respectively) and no sex differences at CVM stages 3, 4, and 5. Conclusions: Skeletal patterns have an effect on airway volume. Sex differences were found in CVM 6.

Evaluation of trueness and precision of removable partial denture metal frameworks manufactured with digital technology and different materials

  • Leonardo Ciocca;Mattia Maltauro;Elena Pierantozzi;Lorenzo Breschi;Angela Montanari;Laura Anderlucci;Roberto Meneghello
    • The Journal of Advanced Prosthodontics
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    • v.15 no.2
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    • pp.55-62
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    • 2023
  • PURPOSE. The aim of this study is to evaluate the accuracy of removable partial denture (RPD) frameworks produced using different digital protocols. MATERIALS AND METHODS. 80 frameworks for RPDs were produced using CAD-CAM technology and divided into four groups of twenty (n = 20): Group 1, Titanium frameworks manufactured by digital metal laser sintering (DMLS); Group 2, Co-Cr frameworks manufactured by DMLS; Group 3, Polyamide PA12 castable resin manufactured by multi-jet fusion (MJF); and Group 4, Metal (Co-Cr) casting by using lost-wax technique. After the digital acquisition, eight specific areas were selected in order to measure the Δ-error value at the intaglio surface of RPD. The minimum value required for point sampling density (0.4 mm) was derived from the sensitivity analysis. The obtained Δ-error mean value was used for comparisons: 1. between different manufacturing processes; 2. between different manufacturing techniques in the same area of interest (AOI); and 3. between different AOI of the same group. RESULTS. The Δ-error mean value of each group ranged between -0.002 (Ti) and 0.041 (Co-Cr) mm. The Pearson's Chi-squared test revealed significant differences considering all groups paired two by two, except for group 3 and 4. The multiple comparison test documented a significant difference for each AOI among group 1, 3, and 4. The multiple comparison test showed significant differences among almost all different AOIs of each group. CONCLUSION. All Δ-mean error values of all digital protocols for manufacturing RPD frameworks optimally fit within the clinical tolerance limit of trueness and precision.

Effect of remimazolam and propofol anesthesia on autonomic nerve activities during Le Fort I osteotomy under general anesthesia: blinded randomized clinical trial

  • Yuto Tsuji;Kyotaro Koshika;Tatsuya Ichinohe
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.24 no.4
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    • pp.273-283
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    • 2024
  • Background: This study evaluated the effect of remimazolam and propofol on changes in autonomic nerve activity caused by surgical stimulation during orthognathic surgery, using power spectrum analysis of blood pressure variability (BPV) and heart rate variability (HRV), and their respective associations with cardiovascular fluctuations. Methods: A total of 34 patients undergoing Le Fort I osteotomy were randomized to the remimazolam (Group R, 17 cases) or propofol (Group P, 17 cases) groups. Observables included the low-frequency component of BPV (BPV LF; index of vasomotor sympathetic nerve activity), high-frequency component of HRV (HRV HF; index of parasympathetic nerve activity), balance index of the low- and high-frequency components of HRV (HRV LF/HF; index of sympathetic nerve activity), heart rate (HR), and systolic blood pressure (SBP). Four observations were made: (1) baseline, (2) immediately before down-fracture, (3) down-fracture, and (4) 5 min after down-fracture. Data from each observation period were compared using a two-way analysis of variance with a mixed model. A Bonferroni multiple comparison test was performed in the absence of any interaction. One-way analysis of variance followed by Tukey's multiple comparisons test was performed when a significant interaction was observed between time and group, with P < 0.05 indicating statistical significance. Results: Evaluation of autonomic nerve activity in comparison with baseline during down-fracture showed a significant increase in BPV LF (P < 0.001), an increasing trend in HRV LF/HF in Group P, and an increasing trend in HRV HF in Group R. There were no significant differences in HR or SBP between the two groups. Conclusion: During down-fracture of Le Fort I osteotomy, sympathetic nerve activity was predominant with propofol anesthesia, and parasympathetic nerve activity was predominant with remimazolam anesthesia.