• The Journal of Internal Korean Medicine
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• v.15 no.2
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• pp.318-346
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• 1994

A Bibliographical study was done about lumbago in oriental internal Medicine. The results are as follows. 1. Shenxu,sexual active, senile, Feng, Han, Shi, shiji, Tanyin and Qi lumbago are applicable to internal medical lumbago in oriental medicine, and Shenxu is essential pathogenesis. 2. Shenxu lumbago is characterized by continous pain, improved after chiropsia, deep pulse in Chi pulse, and used QingeWan, LiuweiDihuangWan and AnshenWan in herb-medicine. and Cortex Eucommiae, Radix Rehmanniae Praeparata and Fructus Psoraleae in drugs for the purpose of ZishenYijing, and related to lumbago caused by chronic prostatitis, calculus or tumor in kidney and diabetes mellitus. 3. Sexual active lumbago is dim-aching and weak pain in or after sexual life at low back and knee joint, and classified to Shenyang Buzu, ShenjingKuisun. GanshenYinxu and XinshenBujiao ; Liuwei Dihuang Wan, ZuoguiWan In herb-medicine. Cornu Cervi Pantotrichum, Fructus Lycii and Fructus Corni in drug were used for treatment. 4. Senile Lumbago is a kind of consumptive disease due to exhaused essential energy and caused by lack of Shenjing, Yangqi ; and described as repeated mild dim pain and ErzhiWan, QingeWan and MoyaoGao were used frequently, supposed to connected with osteoporosis, osteomalacia and osteoarthropathy deformons caused by aging. 5. Feng lumbago is attacked by Liuyin, and characterized by chilling and fever. stabbing pain from thoracic and lumbar vertebrae to pedes, and used WujiXan, XiaoxumingTang for treatment. Han lumbago is caused by cold's attacking Shenjing, distinguished for chilling,icing sense improved by heat on low back, and used WujiXan, JiangfuTang. Shi lumbago is caused by damp's inflowing Shenjing, described as stone-like lumbago which was subsided low back pain growing worse by gloomy rain, and used ShenshiTang. ShenzhuTang for the purpose of ZaoshiXingqi. And it is supposed that lumbago occured in the initial of urinary track infection was belong to those of Feng,Han and Sill's. 6. Sillji lumbago is caused by pathogen being in the spleen and the stomach, and used ChenxiangJiangqiTang, PingweiSan for treatment. And it is supposed that it belong to lumbago caused by gastrointerstinal disease such as peptic ulcer. gastroduodenal tumor and colonic inflammatory disease. 7. Tanyin lumbago is caused by Tanyin's flowing meridian, characterized by thoracolumbar verterber's heaviness, covered sense with something on low back and painless massage. Kuaiqi-drug are added to ErchenTang, DaotanTang for treatment, and it supposed that Tanyin lumbago's belong to that accompanied with metabolic disease such as obesity and gout. 8. Qi lumbago is caused by excessive stress such as melancholy and fury, described as multiple stabbing pain, an unexpected on and improvement, ranging back pain until flank and abdomine. Tiaoqi-drugs were added to RenshenShunqiSan, WuyaoShunqiSan for treatment, and it supposed to connecting with emotional lumbago such as hysteria, feigned illness and anxiety psychosis.

• Journal of the Korea institute for structural maintenance and inspection
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• v.22 no.1
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• pp.147-157
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• 2018

The basis of capacity design has been explicitly or implicitly regulated in most bridge design specifications. It is to guarantee ductile failure of entire bridge system by preventing brittle failure of pier members and any other structural members until the columns provides fully enough plastic rotation capacity. Brittle shear is regarded as a mode of failure that should be avoided in reinforced concrete bridge pier design. To provide ductility behavior of column, the one of important factors is that flexural hinge of column must be detailed to ensure adequate and dependable shear strength and deformation capacity. Eight small scale circular reinforced concrete columns were tested under cyclic lateral load with 4.5 aspect ratio. The test variables are longitudinal steel ratio, transverse steel ratio, and axial load ratio. Eight flexurally dominated columns were tested. In all specimens, initial flexural-shear cracks occurred at 1.5% drift ratio. The multiple flexural-shear crack width and length gradually increased until the final stage. The angles of the major inclined cracks measured from the vertical column axis ranged between 42 and 48 degrees. In particular, this study focused on assessing transverse reinforcement contribution to the column shear strength. Transverse reinforcement contribution measured during test. Each three components of transverse reinforcement contribution, axial force contribution and concrete contribution were investigated and compared. It was assessed that the concrete stresses of all specimen were larger than stress limit of Korea Bridge Design Specifications.

• Journal of the Korean Geotechnical Society
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• v.21 no.10
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• pp.5-16
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• 2005

Geosynthetic-reinforced and pile-supported embankments have been increasingly used and researched around the world. The inclusion of one or multiple geosynthetic reinforcements over the pile is intended to enhance the efficiency of load transfer from soft ground to piles, to reduce total and differential settlement and increase global or local stability. In this paper, the reinforcement effectiveness and arching effect of the geogrid-reinforced and pile-supported embankments have been studied in terms of field model tests and numerical analysis with varying the space between piles and reinforcement. 2-dimensional numerical analysis has been conducted using the FLAC (Fast Lagrangian Analysis of Continua) program. And load transfer mechanisms between soil-piles-geogrid were investigated. The mechanisms of load transfer can be considered as a combination of embankment soil arching, tension geogrid, and stress concentration due to the stiffness difference between pile and soft ground. Based on the field model test and numerical analysis results, it was found that the geosynthetic reinforcement slightly interferes with soil arching, and helps reduce differential settlement of the soft ground. Also. at the D/b=3 (D: spacing of pile cap, b: diameter of pile), the total settlement is reduced by about $40\%$ compared to that without reinforcement. For $D/b{\ge}6$, the effectiveness of geogrid reinforcement in reducing settlement is negligible.

• Journal of Digital Convergence
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• v.16 no.1
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• pp.21-33
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• 2018

This study aims to analyze whether there are mediating effects of emotional labor on the relationship between job characteristics of elderly caregivers and their job satisfaction and burnouts. The sample was consisted of 299 elderly caregivers working for the long-term elderly care centers from Seoul and Kyunggi areas. Both hierarchical multiple regression analysis and mediated regression analysis are used for statistical analysis. The findings from the study are as follow. First, the job characteristics of elderly caregivers have significant effects on their job satisfaction, burnouts, and emotional labor levels after controlling for background variables. Second, emotional labor has a significant effect on burnout, but it has no effect on job satisfaction. Third, there are mediating effects of emotional labor on the relationship between job characteristics of elderly caregivers and their job satisfaction/burnouts. These results suggest that enhanced supervision and stress management education as well as job improvement for elderly caregivers be carried out for the improvement of both their job satisfaction and burnouts. Furthermore, the improvement of the working conditions of elderly caregivers should be paid attention by the government as well as individual elderly care centers.

• Journal of Digital Convergence
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• v.16 no.1
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• pp.409-420
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• 2018

This is a convergence study to investigate the factors affecting the psychological happiness of leisure sports participants(social baseball club) and to present a strategy for effective program development. The subjects of this study were 151 participants of social baseball clubs in J-do area and collected data by self-reported questionnaire. Data were analyzed by descriptive statistics, t-test, ANOVA, correlation analysis and stepwise multiple regression analysis. The results of this study were the explanatory power was 54.1% with psychological happiness, quality of life, self-efficacy. As a result, it was confirmed that strengthening interpersonal relationship ability, positive reinforcement of self-efficacy, and quality of life were important for improvement of psychological happiness. and in the future, it is necessary to study repeatedly to confirm the influence of psychological through objective measurement.

• Journal of Life Science
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• v.23 no.3
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• pp.462-469
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• 2013

Withaferin A is a steroidal lactone purified from the Indian medicinal plant Withania somnifera. It exhibits a wide variety of activities, including anti-tumor, anti-inflammation, and immunomodulation properties. In this review, we focused on the anti-cancer effects of withaferin A. Withaferin A inhibits cell proliferation, metastasis, invasion, and angiogenesis in cancer cells. Furthermore, it sensitized irradiation, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-, and doxorubicin-mediated apoptosis. The results showed that multiple mechanisms were involved in withaferin A-mediated anti-cancer effects. First, withaferin A increased intracellular reactive oxygen species (ROS) production and induced ER stress- and mitochondria-mediated apoptosis. Second, withaferin A inhibited the signaling pathways (Jak/STAT, Akt, Notch, and c-Met), which are important in cell survival, proliferation, and metastasis. Third, it induced apoptosis and inhibited cancer cell migration through the up-regulation of prostate apoptosis protein-4 (Par-4). Finally, withaferin A up-regulated pro-apoptotic protein expression levels through the inhibition of proteasome activity. Our findings suggested that withaferin A is a potential, potent therapeutic agent.

• Journal of Life Science
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• v.28 no.10
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• pp.1233-1243
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• 2018

Sterol regulatory-element binding proteins (SREBPs) are a family of transcription factors that regulate lipid homeostasis and metabolism by controlling the expression of enzymes required for endogenous cholesterol, fatty acid (FA), triacylglycerol, and phospholipid synthesis. The three SREBPs are encoded by two different genes. The SREBP1 gene gives rise to SREBP-1a and SREBP-1c, which are derived from utilization of alternate promoters that yield transcripts in which distinct first exons are spliced to a common second exon. SREBP-2 is derived from a separate gene. Additionally, SREBPs are implicated in numerous pathogenic processes, such as endoplasmic reticulum stress, inflammation, autophagy, and apoptosis. They also contribute to obesity, dyslipidemia, diabetes mellitus, and nonalcoholic fatty liver diseases. Genome-wide analyses have revealed that these versatile transcription factors act as important nodes of biological signaling networks. Changes in cell metabolism and growth are reciprocally linked through SREBPs. Anabolic and growth signaling pathways branch off and connect to multiple steps of SREBP activation and form complex regulatory networks. SREBPs are activated through the PI3K-Akt-mTOR pathway in these processes, but the molecular mechanism remains to be understood. This review aims to provide a comprehensive understanding of the role of SREBPs in physiology and pathophysiology at the cell, organ, and organism levels.

• Korean Journal of Health Education and Promotion
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• v.20 no.2
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• pp.127-147
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• 2003

The purpose of this study was to investigate the factors influencing health promoting behavior and satisfaction of life in female undergraduate students, to provide the basic data for health promoting intervention in order to improve satisfaction of life. The subjects of this study were 345 female undergraduate students living in Jecheon city who were selected by convenience sampling. The data was collected through self-reported questionnaires from Oct. 2 to Dec. 20, 2001. Research instruments used in this study were the health promoting lifestyle profile developed by Walker et al(1987), satisfaction of life developed by Pavot and Diener(1993), perceived health status by Lawston et al(1982), self-esteem by Rosenberg(1965), self-efficacy by Becker et al(1993), health locus of control by Wallston et al(1978). The data was analyzed by using descriptive statistics, pearson correlation coefficient, stepwise multiple regression with SPSS/Win program. The results of this study were as follows； 1) The mean score of health promoting behavior was 2.31 point out of 4. Among the sub-levels of health promoting behavior, the order of importance was the following self-actualization(2.76), interpersonal support(2.75), stress management(2.31), nutrition(2.06), health responsibility(1.83), exercise(1.76). The mean score of satisfaction of life was 4.11 point out of 7. 2) The health promoting behavior showed significant positive correlation with perceived health status, self-esteem, self-efficacy, internal health locus of control, powerful others health locus of control. The satisfaction of life showed significant positive correlation with perceived health status, self-esteem, self-efficacy, internal health locus of control, health promoting behavior. 3) In the relationship between general characteristics and health promoting behavior, there was a significant difference in majors(F＝8.50, p＝.000). In the relationship between general characteristics and satisfaction of life were significant differences in a grades(F＝2.67, p＝.04) and economic status of parents(F＝8.59, p＝.000) 4) The most powerful predictor of health promoting behavior was self-efficacy. A combination of self-efficacy, self-esteem and powerful others health locus of control accounted for 34.7% of the variance in health promoting behavior. The most powerful predictor of satisfaction of life was self-esteem. A combination of self-esteem, health promoting behavior, perceived health status, economic status of parents and grade accounted for 34.0% of the variance in satisfaction of life. In conclusion, we need a health promotion program focusing on exercise, health responsibility and nursing strategies enhancing self-efficacy and self-esteem should be developed to promote a healthy lifestyle and satisfaction of life in female college students.

• Journal of Korean Academy of Nursing
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• v.11 no.1
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• pp.45-63
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• 1981

This study was done to determine the relationship between the anxiety levels of hospitalized psychiatric patients and various influencing variables. The purpose of this study was to determine factors that may help hospitalized psychiatric patients to experience lower levels of anxiety in relation to changing situations and provide the basic data for a dynamic approach which is important in the field of modern psychiatric nursing that understands and analyses the meaning of patients behavior. The anxiety may produce stress, which is a common experience among all human beings. Patients may merely feel uncomfortable in the state of mild anxiety, however, the severe state could be an obstacle to treatment and recovery from disease. The anxiety of the psychiatric patient is a factor which greatly influencing the patient's behavior, so his disorderd behavior is an expression of defence or pathologically fixed behavior. According the psychiatric patient's anxiety at the time of admission is the concern of the health team. The nurse's special concern has to do with understanding and supporting the patient and meeting his individual needs by frequent close contact during the entire hospitalization period, compared to other teamembers the nurse's responsibility in this regard is greated. So this study emphasizes the necessity of creating conditions these, but above all the psychiatric nurse should create a therapeutic environment by not only regarding the patient's behavior or symptoms but understanding the meaning of them. The subjects of this study were 57 psychiatric patients selected from the K neuropsychiatric hospital located in Kunsan city. Data were collected twice from the same patients within a 24 hour period after admission and 10 days after admission. (September 18th to November 8th, 1980). The data collected method was through direct interview, and the interview time was 20 minutes for each patient. Data analysis included Item Analysis & Internal Consistency Reliability Tests, Percentages, t-test, analysis of variance and stepwise multiple regression analysis. The findings of this study were as follows. A. Test of Hypothesis a. Hypothesis 1 :“The anxiety level of psychiatric patients within 24 hours after admission will be higher than those of the same patients 10 days after admission,”was accepted. (t = 3. 15 ; p < 0.005) b. Hypothesi 2:“The more the number of admissions the higher the level of anxiety related to two categories”, was accepted. (affective anxiety: F = 5.50, p < 0.005, Somatic anxiety: F = 9.12, p <.

• Journal of the Korean Society of Safety
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• v.25 no.6
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• pp.169-179
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• 2010

The aim of this study was to investigate occupational and individual risk factors and working conditions in relation to musculoskeletal symptoms in street cleaners. Investigation was conducted through a survey of 395 male street cleaners employed by the government office in Seoul, Gyeonggi and Chung-Nam from July to August of 2009. The control group was comprised of 143 male drivers and security guards. Risk factors for musculoskeletal symptoms in street cleaners were investigated by multiple logistic regression analysis and also evaluated ergonomic risk factors by assessing working conditions of 4 street cleaners. As a result of symptom questionnaires, all of the prevalent rates of musculoskeletal symptoms in street cleaners had significantly higher results than those of the control group(p<0.05). On binary logistic regression analysis of musculoskeletal symptoms, street cleaners showed significant higher odds ratio as 18.84(95%CI: 6.56-54.12) in the arm/elbow, 10.49(95%CI: 4.29-25.65) in the hand/wrist compared to the control group. Both absence of rest breaks and exposure to ergonomic risk factors showed to be important internal risk factors of musculoskeletal symptoms among street cleaners. The exposure levels of QEC(Quick exposures checklist) in street cleaners were revealed to be higher on the shoulder/arm, wrist/hand, and neck than back, or from stress. The findings appear to show that street cleaners were high-risk group of work-related musculoskeletal disorders. Therefore street cleaners require a holistic interventional strategy, including adequate arrangement of rest breaks, improvement of working tools and control of individual risk factors such as obesity and smoking.