• Title/Summary/Keyword: Multiple Cell

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Effects of intravenous multiple busulfan injection on suppression of endogenous spermatogenesis in recipient stallion testes

  • Jung, Heejun;Yoon, Minjung
    • Journal of Animal Science and Technology
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    • v.63 no.5
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    • pp.1194-1203
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    • 2021
  • Preparation of recipient stallions is critical step to produce donor spermatogonial stem cell (SSC) derived sperm using transplantation technique. This study was conducted to evaluate the effects of intravenous busulfan infusion on germ cell depletion, semen production, and libido in stallions. Six Thoroughbred stallions were separated into two treatment groups: 1) a multiple low-dose (2.5 mg/kg bw for the first 4 weeks and 5 mg/kg bw for the 5th week); and 2) control group treated with PBS. Testicular samples were obtained at 11 weeks and classified into three different patterns of spermatogenesis, such as normal, Sertoli cell only, and destroyed. Semen collection and libido experiments were performed 1 week before treatment, and 4 and 8 weeks after treatment. For the sperm analysis, total spermatozoa and motility were measured using a light microscope with a motility analyzing system. In the multiple low-dose group, the numbers of tubules categorized as Sertoli cell only were significantly higher than those in the control as well as the total population and total/progressive motility of sperm were significantly decreased 8 weeks after the start of the treatment. The sperm production and motility in the multiple low-dose group appears to be reduced, while libido was maintained. In conclusion, multiple administration of 2.5 mg/kg bw busulfan depletes endogenous germ cells in the stallion recipients for SSC transplantation.

RADIOLOGIC STUDY OF BASAL CELL NEVUS SYNDROME (기저세포모반 증후군의 방사선학적 연구)

  • Park Tae Won
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.18 no.1
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    • pp.5-12
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    • 1988
  • Several cases of jaw cyst-basal cell nevus-bifid rib syndrome are presented. This syndrome consists principally of multiple jaw cysts, basal cell nevi, and bifid ribs but no one component is present in all patients. The purpose of this paper is to review the multiple characteristics of this syndrome and present three cases in a family and additional 4 cases. The many malformations associated with the syndrome have variable expressivity. In the cases, multiple jaw cysts, palmar and plantar pittings, bridging of sella, temporoparietal bossing, hypertelorism, cleft palate, and dystopia canthorum have been observed.

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A Rare Case of Intestinal T-cell Lymphoma with Multiple Complications

  • Seung Yong Shin
    • Journal of Digestive Cancer Research
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    • v.11 no.2
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    • pp.114-118
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    • 2023
  • Intestinal T-cell lymphoma is a rare and aggressive form of non-Hodgkin lymphoma. Owing to its rarity and variable manifestations, intestinal T-cell lymphoma is usually diagnosed at an advanced stage. Therefore, it may be accompanied with serious complications at the time of diagnosis. Herein, I reports a case of intestinal T-cell lymphoma with multiple severe complications.

The Effects of ASMase Mediated Endothelial Cell Apoptosis in Multiple Hypofractionated Irradiations in CT26 Tumor Bearing Mice

  • Zhu, Hong;Deng, Kai;Zhao, Ya-Qin;Wang, Xin;Shen, Ya-Li;Liu, Tai-Guo;Cui, Dan-Dan;Xu, Feng
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.11
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    • pp.4543-4548
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    • 2015
  • Background: To investigate the effects of ASMase mediated endothelial cell apoptosis in multiple hypofractionated irradiations in CT26 tumor bearing mice. Materials and Methods: Thirty-five CT26 tumor bearing mice were subjected to single ionizing radiation (IR) of 0, 3, 6, 9, 12, 15, 18 Gy. Eight hours after IR, the mice were sacrificed and tumor tissues were used for CD31 immunohistochemistry staining, TUNEL and CD31 double staining, ASMase activity assay. Then 6 and 12 Gy were chosen for multiple hypofractionated IR experiments according to the above results. Each time after IR, 5 mice were sacrificed and assayed as above. Results: The ASMase activities were increased significantly after a single IR of 12 Gy or higher which was accompanied with remarkable increased endothelial cell apoptosis and decreased MVD. For 6 Gy which was not high enough to trigger ASMase activation, after 2 or more times of IR, the ASMase activities were significantly increased accompanied with remarkable increased endothelial cell apoptosis and decreased MVD. While for 12 Gy, after 2 or more times of IR, the ASMase activities and endothelial cell apoptosis rates were maintained without remarkable increase; however, the MVD was significantly decreased. What's more, the cancer cell apoptosis rates were significantly increased after multiple IR for both 6 Gy and 12 Gy. Conclusions: ASMase mediated endothelial cell apoptosis may play an important role in the process of multiple hypofractionated IR for CT26 colorectal carcinoma.

Cell Searching and DoA Estimation Method for a Mobile Relay with Multiple Antennas (다중 안테나를 갖는 이동 릴레이의 셀 탐색과 입사각 추정방법)

  • Ko, Yo-Han;Kang, Hyun-Jin;Cho, Yong-Soo
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.44 no.5
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    • pp.63-69
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    • 2007
  • propose a mobile relay structure for vehicles with multiple antennas, which can increase performances of mobile communication systems and broadcasting systems significantly. Since cell searching and DoA estimation are required for the terminal in hard handover cellular system, joint techniques for cell searching and DoA estimation are proposed to apply beamforming technique for the mobile relay with multiple antennas located at the cell boundary. The proposed cell searching and DoA estimation techniques are evaluated by computer simulation under the environment similar to WiBro system.

A CASE REPORT OF MULTIPLE ODONTOGENIC KERATOCYSTS ASSOCIATED WITH BASAL CELL NEVUS SYNDROME (기저세포모반증후군과 관련된 악골의 다발성 치성각화낭종의 치험례)

  • Byun, June-Ho;Park, Seong-Hee;Kim, Uc-Kyu;Park, Hae-Ryoun;Chung, In-Kyo
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.26 no.3
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    • pp.305-309
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    • 2000
  • The basal cell nevus syndrome is a well recognized entity, the major symptoms of which are basal cell nevi, multiple jaw cysts, skeletal anomalies, and ectopic calcification. The syndrome follows a hereditary pattern, which is characterized by a highly penetrant, autosomal dominant gene with multiple and variable effects. The patient often has a characteristic face, with frontal and temporoparietal bossing, which results in an increased cranial circumference. The eyes may appear widely separated, and 40 percent of patients have true ocular hypertelorism. Jaw cysts are one of the most constant features of the syndrome and are present in at least 75 percent of the patients. The cysts are odontogenic keratocysts and frequently multiple. Radiographically, the cysts in patients with basal cell nevus syndrome do not differ significantly from isolated keratocysts. The cysts in patients with this syndrome are often associated with the crowns of unerupted teeth; on radiographs they may mimic dentigerous cysts. We report a case of multiple odontogenic keratocysts associated with basal cell nevus syndrome with the literature of review.

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A Flexible Conveying System using Hybrid Control under Distributed Network

  • Yeamglin, Theera;Charoenseang, Siam
    • Proceedings of the IEEK Conference
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    • 2002.07a
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    • pp.583-586
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    • 2002
  • In this research, we propose a flexible conveying system (FCS) which consists of multiple arrays of cells. Each cell is a wheel driven by a two degree-of-freedom mechanism. The direction and velocity of cell are controlled based on the concept of hybrid control under a distributed network. Each cell has its own controller under a subsumption architecture for low-level control. A cell communicates with its four neighboring cells to manipulate n targeted object towards its desired position. The high-level control assigns a desired position and direction of the object to each cell. The path of each object is generated by many supporting cells. Moreover, the FCS can handle multiple objects simultaneously. To study the flexible conveying system, a GUI-based simulator of flexible conveying system is constructed. The simulated results show that the system can handle multiple objects independently and simultaneously under the proposed hybrid control architecture.

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Multiple jaw cysts not associated with basal cell nevus syndrome (기저세포모반증후군을 동반하지 않은 다발성 악골낭 두 증례)

  • Yoon Suk-Ja;Kang Byung-Cheol
    • Imaging Science in Dentistry
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    • v.33 no.3
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    • pp.195-198
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    • 2003
  • We present two cases of multiple jaw cysts not associated with basal cell nevus syndrome. Case 1: a nine year-old boy visited CNU Hospital for orthodontic treatment and his radiographs showed cystic lesions surrounding the crowns of teeth #13 and #17 respectively, which were diagnosed as dentigerous cysts. Subsequently, two more cysts were found on his follow-up radiographs in 12 and 15 months. The two cysts were determined to be odontogenic keratocysts. The boy had no skeletal abnormalities and no skin lesions associated with basal cell nevus syndrome. Case 2: a fifty-eight year old man had three impacted third molars with pericoronal radiolucencies, which were diagnosed as dentigerous cysts. He had no additional abnormalities associated with basal cell nevus syndrome. Multiple jaw cysts can occur at any age, and periodic radiographic surveillance may be needed for any cases of impacted tooth.

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Novel Beamforming and Scheduling Method for Interference Mitigation at Cell Edge (셀 경계 지역 간섭 완화를 위한 효율적 빔포밍 및 스케쥴링 방법)

  • Kim, Kyung Hoon;Choi, Seung Won
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.8 no.4
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    • pp.129-133
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    • 2012
  • Coordinated multi-point transmission (CoMP) is a candidate technique for next generation cellular communications systems. One of the primary elements discussed in LTE-Advanced technology is CoMP, which can improve cell edge user data rate as well as spectral efficiency due to multiple input multiple output - orthogonal frequency division multiplex (MIMO-OFDM). We consider a system with multiple cells in which base stations coordinate with each other by sharing user channel state information (CSI), which mitigates inter cell interference (ICI), especially for users located at the cell edge. We introduce a new user scheduling method of ICI cancellation and the loss reduction of effective channel gain during the beamforming process, the proposed method improves the system sum rate, when compared to the conventional method by an average of 0.55bps/Hz in different number of total users per cell. It also outperforms the conventional method by approximately 0.38bps/Hz using different SNRs.

An assignment method for part-machine cell formation problem in the presence of multiple process routes

  • Won, You-Kyung;Kim, Sehun
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 1994.04a
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    • pp.236-243
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    • 1994
  • In this paper we consider the part-machine cell formation decision of the generalized Group Technology(GT) problem in which multiple process routes can be generated for each part. The existing p-median model and similarity coefficient algorithm can solve only small-sized or well-structured cases. We suggest an assignment method for the cell formation problem. This method uses an assignment model which is a simple linear programming. Numerical examples show that our assignment method provides good separable cells formation even for large-sized and ill-structured problems.