• Tuberculosis and Respiratory Diseases
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• 제86권4호
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• pp.264-271
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• 2023

Chronic cough is a common problem that can be refractory to medical treatment. Nonpharmaceutical management of chronic cough has an important role in well selected patients. This review article outlines the history of chronic cough management, current approaches to speech pathology management of the condition and new modalities of nonpharmaceutical treatment. There is a need for further research into nonpharmaceutical options with well described randomised control trials.

• Radiation Oncology Journal
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• 제22권1호
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• pp.1-10
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• 2004

비소세포성 폐암에서 국소 진행성 병변(병기 3)이 3분의 1을 차지한다. 이 중 완전 절제가 가능한 소수의 환자를 제외하고 대부분의 환자에서 근치적 방사선치료가 전통적으로 시행되어 왔다. 하지만 근치적 방사선치료 후 장기 생존율은 극히 불량하고, 대개의 경우 원격 전이 또는 국소 재발로 사망하게 된다. 지난 20년간, 집합적 요법으로 국소 진행성 비소세포성 폐암 치료효과의 향상이 있었다. 그중 화학방사선요법이 가장 흔히 사용되었고, 화학요법과 방사선치료를 병용하는 순서에 따라 다음 두 가지 기본적 방법이 있다. 즉, 순차적 요법과 동시 요법이 그것이다. 순차적 병용 요법은 유도 화학요법 완료 후 방사선 치료를 진행하는 순서로 주로 시행되었다. 근거로는 방사선 치료전 유도 화학요법 사용 으로 종양의 크기를 줄여 국소제어율을 높이고, 보이지 않는 미세 전이 병변을 제거하여 원격 전이를 감소시키는 데 있다. 방사선 단독 치료와 비교하여 순차적 화학방사선요법으로 중앙생존기간과 장기생존율의 향상을 보고한 여러 연구가 있다. 재발 양상을 분석한 보고에 따르면, 방사선치료 단독과 비교하여 순차적 병용요법이 원격전이율은 감소시키나, 국소 재발률에는 영향이 없었다. 화학요법과 방사선치료를 동시 시행하는 동시병용요법에 대한 많은 보고가 있다. 근거로는 화학요법을 방사선과 동시 투여함으로써 화학요법에 의한 종양세포 방사선 감작효과를 기대할 수 있고, 순차적요법과 비교하여 전체 치료기간을 단축하여 국소제어율을 향상시킬 수 있다. 기대했던 대로 동시 병용요법 후 국소 제어율 향상과 이로 인한 생존율 증가가 관찰되었다. 하지만 방사선 치료 단독과 비교하여 원격 전이율에는 차이가 없었고, 이는 급성 부작용, 특히 급성 식도염 위험을 줄이기 위해 대다수의 연구에서 관찰되듯이 화학요법의 강도를 줄인 때문으로 생각된다. 상기한 바와 같이 집합적 치료가 방사선 단독 요법과 비교하여 생존율의 향상에 기여하였고, 현재 새 표준 치료로 정착되었으나, 이의 치료효과는 아직도 실망스러우며, 최적 치료 개발을 위한 연구는 계속되어야 한다. 본 보고에서 국소 진행 비소세포성 폐암에서 집합적 치료에 대한 현 논점을 검토하고자 한다.

• 한국컴퓨터정보학회논문지
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• 제18권8호
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• pp.167-174
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• 2013

본 연구는 21세기에 필요한 핵심적인 학습 능력을 연구하고 미래 사회 국가 발전에 필요한 핵심 인력을 양성하는데 있다. '21세기 학습 능력 프로젝트'는 학습자의 학습 능력과 개인 회적으로 가치 있는 주제를 중심으로 기존 지식과 학문을 다학문적, 통합적으로 접근 하는 것이다. 국내에서도 학습 능력 배양을 위한 다양한 교과 간 통합 교육과정의 시도가 있었으나 각 교과의 내용과 특성의 차이를 충분히 이해하여 효과적으로 교수할 수 있는 교사가 부족하고 현장에서 쉽게 적용하는데 어려움이 있다. 이에 본 연구는 21세기에 필요한 학습 능력 신장을 위해 학문의 지식을 통합하는 다학문적 맞춤형 교육과정을 개발하고 이를 효율적으로 지원하기위해 교육과정 실태를 분석 연구하고 그 결과로 초 중등학교에 적용할 수 있는 다학문 맞춤형 학문 통합 모형을 제안한다.

• 대한치과교정학회지
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• 제49권1호
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• pp.59-69
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• 2019

In this report, we describe a case involving a 34-year-old woman who showed good treatment outcomes with long-term stability after multidisciplinary treatment for unilateral cleft lip and palate (CLP), maxillary hypoplasia, severe maxillary arch constriction, severe occlusal collapse, and gingival recession. A comprehensive treatment approach was developed with maximum consideration of strong scar constriction and gingival recession; it included minimum maxillary arch expansion, maxillary advancement by distraction osteogenesis using an internal distraction device, and mandibular setback using sagittal split ramus osteotomy. Her post-treatment records demonstrated a balanced facial profile and occlusion with improved facial symmetry. The patient's profile was dramatically improved, with reduced upper lip retrusion and lower lip protrusion as a result of the maxillary advancement and mandibular setback, respectively. Although gingival recession showed a slight increase, tooth mobility was within the normal physiological range. No tooth hyperesthesia was observed after treatment. There was negligible osseous relapse, and the occlusion remained stable after 5 years of post-treatment retention. Our findings suggest that such multidisciplinary approaches for the treatment of CLP with gingival recession and occlusal collapse help in improving occlusion and facial esthetics without the need for prostheses such as dental implants or bridges; in addition, the results show long-term post-treatment stability.

• 농촌지도와개발
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• 제7권2호
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• pp.359-376
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• 2000

The purposes of this exploratory study were to interrelate the scholastic discipline of the ‘development communication’ into ‘community development’ and ‘adult education’ in terms of interests, views and theoretical backgrounds of these fields of social sciences; and to draw some implications for developing scholastic interactions among these fields to pursue common social changes of human society. Development communications provide opportunities to set goals, to decide contents, and to utilize communication media in developmental efforts. Contemporary trends of development communication, community development and adult education are concerned with indigenous, two-way, bottom-up and people-centered communication from exogenous, one-way, top-down and institution-centered communication of the past. Multidisciplinary approaches to communication concepts and methodology may increase the potentials of community development and adult education in terms of efficiency and effectiveness. Some of the development communication approaches such as traditional and folk media approach. new media or ICT(information & communication technology) approach, participatory communication for development approach, communication support development approach and mass media approach may be applicable for community development and adult education. Better understanding on development communication approaches will be needed for the adult educators as well as community development practitioners.

• Journal of Korean Neurosurgical Society
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• 제45권1호
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• pp.39-42
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• 2009

We report a supratentorial primitive neuroectodermal tumor (sPNET) in 17-year-old primipara in the second trimester her pregnancy. Magnetic resonance imaging revealed a left frontoparietal mass with solid and cystic component. Gross-total resection was achieved via a left frontoparietal craniotomy. It was decided to suspend the radiotherapy and chemotherapy until the 30 weeks of gestation. But, a sudden uncal herniation was developed due to the reccurrence of the tumor and bleeding into the tumor at the 25 weeks of gestation and the patient died after urgent decompressive surgery. sPNETs is an extremely rare brain tumor in pregnancy and only two cases were reported in the literature to date. There is no universally agreed treatment protocol for sPNETs during pregnancy and a multidisciplinary approach is required in treatment. In the present study, the clinical, histopathological features and therapeutical difficulties of sPNETs diagnosed during pregnancy was discussed with the literature review.

• 한국태양에너지학회 논문집
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• 제32권5호
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• pp.1-10
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• 2012

This paper proposes a modeling and controller design approach for a wind-diesel hybrid system including dump load. Wind turbine depends on nature such as wind speed. It causes power fluctuations of wind turbine. Excessive power fluctuation at stand-alone power grid is even worse than large-scale power grid. The proposed control scheme for power quality is fuzzy PI controller. This controller has advantages of PI and fuzzy controller. The proposed model is carried out by using Matlab/Simulink simulation program. In the simulation study, the proposed controller is compared with a conventional PI controller. Simulation results show that the proposed controller is more effective against disturbances caused by wind speed and load variation than the PI controller, and thus it contributes to a better quality wind-diesel hybrid power system.

• 대한기계학회논문집A
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• 제25권2호
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• pp.182-191
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• 2001

The paper describes the improvement on concurrent subspace optimization(CSSO) via automatic differentiation. CSSO is an efficient strategy to coupled multidisciplinary design optimization(MDO), wherein the original design problem is non-hierarchically decomposed into a set of smaller, more tractable subspaces. Key elements in CSSO are consisted of global sensitivity equation, subspace optimization, optimum sensitivity analysis, and coordination optimization problem that require frequent use of 1st order derivatives to obtain design sensitivity information. The current version of CSSO adopts automatic differentiation scheme to provide a robust sensitivity solution. Automatic differentiation has numerical effectiveness over finite difference schemes tat require the perturbed finite step size in design variable. ADIFOR(Automatic Differentiation In FORtran) is employed to evaluate sensitivities in the present work. The use of exact function derivatives facilitates to enhance the numerical accuracy during the iterative design process. The paper discusses how much the automatic differentiation based approach contributes design performance, compared with traditional all-in-one(non-decomposed) and finite difference based approaches.

• 기술혁신연구
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• 제10권1호
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• pp.22-37
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• 2002

The importance of selecting the strategic research field is increasingly emphasized by research manager and technology policy-maker in perspective of the strategic allocation of R&D resources, employing the R&D personnel, and formulating technology policy. Among various methods for selecting the strategic research field, it is, however, very difficult to find the method that involves the path-dependant trend, and interdisciplinary nature of technology development. This study suggests modified technology cluster analysis (TCA) as a method for selecting strategic research field in order to include the recent technology trend in quantitative approach. TCA is the method that groups the near technologies of which the innovation pattern is similar. TCA model can be a very necessary method for multidisciplinary government research institutes (GRIs) which conduct multi research field with forward oriented positioning. It is more difficult for them to select the strategic research field mainly due to their diversity and intangibility of research scope. In this study, we applied this method to Korea Institute of Science and Technology (KIST) which represents the most adequate research institute in terms of research diversity and forwardness. As a result of the application, we found that seven main technology groups come from TCA analysis, coincide with the technology topics of KIST's recent R&D planning. Even though this method designed for multidisciplinary research institutes, but it also can be used for establishing the research strategy of other (private or public) Research Institute which have the similar mission and scope of research.

• 한국항공우주학회지
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• 제47권3호
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• pp.228-239
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• 2019

단거리 탄도 미사일의 개념 형상을 설계하기 위하여, 부피, 공력, 추진, 구조, 안정성, 비행 궤적 등의 다양한 관점을 고려하는 최적화 문제를 정립하였다. 이를 위하여 기존의 미사일 사례를 분석하여, 설계 조건과 성능지수를 도출하였다. 각 서브 시스템의 모델을 통합하여, 전체 시스템의 성능을 분석하였다. 설계 예시를 통하여, 여러 설계변수가 최종 성능에 미치는 관계성을 분석하였다.