• 제목/요약/키워드: Multi-objectives

검색결과 780건 처리시간 0.03초

후두 미세수술 중 병변 내 스테로이드 주입이 음성에 미치는 효과 분석 (Analysis of the Effect of Intralesional Steroid Injection on the Voice During Laryngeal Microsurgery)

  • 박재선;강현석;이인범;진성민;이상혁
    • 대한후두음성언어의학회지
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    • 제33권3호
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    • pp.166-171
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    • 2022
  • Background and Objectives Vocal fold (VF) scar is known to be the most common cause of dysphonia after laryngeal microsurgery (LMS). Steroids reduce postoperative scar formation by inhibiting inflammation and collagen deposition. However, the clinical evidence of whether steroids are helpful in reducing VF scar formation after LMS is still lacking. The purpose of this study is to determine whether intralesional VF steroid injection after LMS helps to reduce postoperative scar formation and voice quality. Materials and Method This study was conducted on 80 patients who underwent LMS for VF polyp, Reinke's edema, and leukoplakia. Among them, 40 patients who underwent VF steroid injection after LMS were set as the injection group, and patients who had similar sex, age, and lesion size and who underwent LMS alone were set as the control group. In each group, stroboscopy, multi-dimensional voice program, Aerophone II, and voice handicap index (VHI) were performed before and 1 month after surgery, and the results were statistically analyzed. Results There were no statistically significant differences in the distribution of sex, age, symptom duration, occupation and smoking status between each group. Both groups consisted of VF polyp (n=21), Reinke's edema (n=11), and leukoplakia (n=9). On stroboscopy, the lesion disappeared after surgery, and the amplitude and mucosal wave were symmetrical on both sides of the VFs in all patients. Acoustic parameters and VHI significantly improved after surgery in all patients. However, there was no significant difference between the injection and control group in most of the results. Conclusion There was no significant difference in the results of stroboscopy, acoustic, aerodynamic, and subjective evaluation before and after surgery in the injection group and the control group.

성대주입술 후 음향학적 분석결과 비교: 암의 신경 침윤으로 인한 일측성 성대마비 환자와 수술 후 발생한 일측성 성대마비 환자 (Comparison of the Voice Outcome After Injection Laryngoplasty: Unilateral Vocal Fold Paralysis Due to Cancer Nerve Invasion and Iatrogenic Injury)

  • 조용민;최현석;오경호;백승국;우정수;권순영;정광윤;조재구
    • 대한후두음성언어의학회지
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    • 제33권3호
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    • pp.172-178
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    • 2022
  • Background and Objectives Injection laryngoplasty is a common method for treatment of unilateral vocal fold paralysis. Unilateral vocal fold paralysis has various causes, including idiopathic, infection, stroke, neurologic condition, surgery and nerve invasion by cancer. To the knowledge of the authors, there was no study on the relationship between the causes of vocal cord paralysis and the outcome of injection laryngoplasty. Therefore, we tried to investigate the difference in the outcomes of injection laryngoplasty between vocal cord paralysis after surgery group and nerve invasion by cancer group. Materials and Method A retrospective analysis was performed for 24 patients who underwent vocal cord injection due to unilateral vocal cord paralysis caused by surgery or nerve invasion by cancer. The objective quality of the voice was assessed by acoustic voice analysis with the Multi-Dimensional Voice Program. Results Both group showed an improvement of fundamental frequemcy (F0), jitter percent, shimmer (percent), and noise to hearmonic ratio (NHR) after injection laryngoplasty. The vocal cord paralysis due to nerve invasion group showed more improvement in both the mean and median value of F0, shimmer percent and NHR than the vocal cord paralysis due to surgery group, but there was not statistically significant. Conclusion Our study did not show a statistically significant difference in outcome between vocal cord paralysis due to cancer invasion group and surgery group, but statistically tendency was suggested. The vocal cord paralysis due to nerve invasion group showed more improvement in both the mean and median value of acoustic voice analysis than surgery group.

전탕 전과 후의 한약재 및 처방에 포함된 위해물질의 농도변화 -다빈도 한약 처방을 중심으로- (Concentration of Hazardous Substances of Before/after a Decoction- In Prescription of High Frequency -)

  • 서창섭;황대선;이준경;하혜경;천진미;엄영란;장설;신현규
    • 대한본초학회지
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    • 제24권2호
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    • pp.13-20
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    • 2009
  • Objectives: To compare the contents of hazardous substances before/after a decoction. Methods : The heavy metal contents before/after a decoction were measured by Inductively Coupled Plasma Atomic Emission Spectrometer (ICP-AES) and mercury analyzer. In order to analyze pesticides in 6 samples we used simultaneous multi-residue analysis of pesticides by GC/ECD, which was followed by GC/MSD analysis to confirm the identity of the detected pesticide in each sample. In addition, the contents of sulfur dioxide (S02) were performed by Monier-Williams distillation method. Results : 1. The mean values of heavy metal contents (mg/kg) for the samples were as follows: Socheongryong-tang (before decoction - Pb; 1.115, Cd; 0.179, As; 0.069 and Hg; 0.028, after decoction - Pb; 0.110, Cd; 0.011, As; 0.005 and Hg; 0.002), Insampaedok-san (before decoction - Pb; 1.207, Cd; 0.148, As; 0.171 and Hg; 0.026, after decoction - Pb; 0.075, Cd; 0.006, As; not detected and Hg; O.OOD, Oryung-san (before decoction - Pb; 1.955, Cd; 0.430, As; 0.063 and Hg; 0.027, after decoction - Pb; 0.083, Cd; 0.013, As; 0.006 and Hg; 0.002), Hwangryunhaedok-tang (before decoction - Pb; 1.825, Cd; 0.210, As; 0.050 and Hg; 0.009, after decoction - Pb; 0.107, Cd; 0.010, As; 0.005 and Hg; O.OOD, Bangpungtongseong-san (before decoction - Pb; 1.740, Cd; 0.162, As; 0.585 and Hg; 0.018, after decoction - Pb; 0.041, Cd; 0.006, As; 0.022 and Hg; not detected) and Oyaksungi-san (before decoction - Pb; 1.199, Cd; 0.183, As; 0.321 and Hg; 0.031, after decoction - Pb; 0.096, Cd; 0.008, As; 0.021 and Hg; 0.0004). 2. Contents (mg/kg) of sulfur dioxide (S0$_2$) before a decoction in Socheongryong-tang, Insampaedok-san, Oryung-san, Hwangryunhaedok-tang, Bangpungtongseong-san and Oyaksungi-san exhibited 3.2, 5.7, 4.5, 49.8, 7.8 and 22.4, respectively. However, contents of sulfur dioxide after a decoction in all samples were not detected. 3. Contents (mg/kg) of residual pesticides before/after a decoction in all samples were not detected. Conclusions : These results will be used to establish a criterion of heavy metals, residual pesticides and sulfur dioxide.

전탕 전과 후의 중금속, 잔류농약 및 잔류이산화황의 농도변화 - 소화기계 약을 중심으로 - (Concentration of Heavy Metals, Residual Pesticides and Sulfur Dioxide of before/after a Decoction - In Prescription of Digestive System -)

  • 서창섭;황대선;이준경;하혜경;천진미;엄영란;장설;신현규
    • 대한본초학회지
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    • 제24권1호
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    • pp.111-119
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    • 2009
  • Objectives : To compare the contents of hazardous substances before/after a decoction. Methods : The heavy metal contents before/after a decoction were measured by Inductively Coupled Plasma Atomic Emission Spectrometer (ICP-AES) and mercury analyzer. In order to analyze pesticides in 6 samples we used simultaneous multi-residue analysis of pesticides by GC/ECD, which was followed by GC/MSD analysis to confirm the identity of the detected pesticide in each sample. In addition, the contents of sulfur dioxide (SO2) were performed by Monier-Williams distillation method. Results : 1. The mean values of heavy metal contents (mg/kg) for the samples were as follows: Samchulkunbi-tang (before decoction - Pb; 1.592, Cd; 0.155, As; 0.055 and Hg; 0.014, after decoction - Pb; 0.036, Cd; 0.002, As; not detected and Hg; 0.001), Yijin-tang (before decoction - Pb; 0.830, Cd; 0.077, As; 0.045 and Hg; 0.015, after decoction - Pb; 0.193, Cd; 0.010, As; not detected and Hg; 0.002), Banhabaikchulcheunma-tang (before decoction - Pb; 0.976, Cd; 0.164, As; 0.167 and Hg; 0.019, after decoction - Pb; 0.031, Cd; 0.003, As; 0.006 and Hg; 0.005), Pyungwi-san (before decoction - Pb; 2.162, Cd; 0.128, As; 0.061 and Hg; 0.018, after decoction - Pb; 0.080, Cd; 0.006, As; not detected and Hg; 0.005), Leejung-tang (before decoction - Pb; 1.480, Cd; 0.294, As; 0.034 and Hg; 0.012, after decoction - Pb; 0.064, Cd; 0.007, As; 0.007 and Hg; 0.002) and Kwibi-tang (before decoction - Pb; 0.907, Cd; 0.193, As; 0.085 and Hg; 0.020, after decoction - Pb; 0.072, Cd; 0.006, As; 0.004 and Hg; 0.002). 2. Contents (mg/kg) of sulfur dioxide ($SO_2$) before a decoction in Banhabaikchulcheunma-tang, Pyungwi-san, Leejung-tang and Kwibi-tang exhibited 3.5, 3.4, 3.8 and 12.4, respectively. However, contents of sulfur dioxide after a decoction in all samples were not detected. 3. Contents (mg/kg) of residual pesticides before/after a decoction in all samples were not detected. Conclusions : These results will be used to establish a criterion of heavy metals, residual pesticides and sulfur dioxide.

급성기 중풍환자의 설진(舌診)과 National Institute of Health Stroke Scale과의 상관성 연구 - 다기관 임상연구 (The Relationship between Tongue Diagnosis and National Institute of Health Stroke Scale in Acute Stroke Patients - Multi Center Trials)

  • 이인환;신애숙;곽자영;조승연;박성욱;박정미;고창남;조기호;배형섭
    • 대한중풍순환신경학회지
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    • 제9권1호
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    • pp.1-7
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    • 2008
  • Objectives : We questioned whether the tongue diagnosis is effective for judging seriousness of cerebrovascular accidents. This study is about the relationship between tongue diagnosis and National Institute of Health Stroke Scale(NIHSS) in acute stroke patients. Methods : 738 subjects were recruited from the patients admitted to the department of internal medicine at Kyung-Hee University oriental medical center, Kyung-Hee University East-West Neo Medical Center, Kyungwon university Incheon oriental medical center, Kyungwon university Songpa oriental medical center and DongGuk university Ilsan oriental medical center from April 2007 to August 2008. We looked at the tongue as in three dimensions of tongue color, tongue fur color and tongue body. And, we calculated NIHSS means according to the subtypes of three dimensions. Results : 1. In the Tongue color, from the most commom to least common colors were pale red, red, pale, bluish purple, and ect. The NIHSS mean score of red is significantly higher than pale and pale red. 2. In the Tongue fur color, white fur was the most common, and then yellow fur, etc. There is no significant difference among three subtypes in the NIHSS mean score. 3. In the Tongue body, etc. is the most common, followed by teeth-marked tongue, enlarged tongue, blood patchy tongue, and mirror tongue. The NIHSS mean score of teeth-marked tongue is significantly lower than blood patchy tongue and mirror tongue. Conclusions : The tongue color and the tongue body are useful indexes for judging seriousness of cerebrovascular accidents presented by NIHSS. But in our study, the tongue fur color was not useful. Further study is necessary on the tongue fur.

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급성기 중풍 환자들의 위험요인 및 중풍유형과 변증분형의 관련성 연구 (The Relationship between Stroke Risk Factors, Stroke Subtypes and Diagnostic Pattern in Korean Medicine of Acute Stroke - Multi Center Trials)

  • 신애숙;이인환;곽자영;조승연;박성욱;박정미;고창남;조기호;배형섭
    • 대한중풍순환신경학회지
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    • 제9권1호
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    • pp.19-24
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    • 2008
  • Objectives : This study was conducted as part of the national project to standardize stroke diagnosis in Korean medicine. In this study, we assessed what categories of stroke diagnosis these three most common risk factors of cerebro-vascular attack(CVA), hypertension(HTN), diabetes mellitus(DM) and hyperlipidemia(HL) fall into. Also we looked into stroke subtypes and its diagnosis in Korean medicine. Methods : 806 patients with acute stroke from 5 universities(Kyung-Hee University oriental medical center, Kyung-Hee University East-West Neo Medical Center, Kyungwon university Incheon oriental medical center, Kyungwon university Songpa oriental medical center and DongGuk university Ilsan oriental medical center) across the country were involved from April, 2007 til August, 2008. We had data of 482 patients to be analyzed and diagnosed by a Korean medicine training doctor and a professor. Results : All three major stroke risk factors were diagnosed as being dampness-phlegm pattern, but no significant difference was observed except in hyperlipidemia patients. Stroke subtypes such as hemorrhage and infarction showed no significant difference in this study. Conclusions : This study provides evidence that hyperlipidemia can be diagnosed as dampness-phlegm by Korean medicine. Further studies with various subtypes of stroke patients are required to prove solid evidence with other stroke risk factors.

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Early childhood eating behaviors associated with risk of overweight and its socio-ecological determinants in Korean preschool children

  • Yeri Kim ;Jiye Kim ;Bomi Lee ;Seungyoun Jung;Seo-Jin Chung ;Hyekyeong Kim ;Nana Shin ;Yuri Kim
    • Nutrition Research and Practice
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    • 제17권4호
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    • pp.717-734
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    • 2023
  • BACKGROUND/OBJECTIVES: This study aimed to identify preschool children's eating behaviors associated with early childhood obesity and its multi-level, socio-ecological determinants. SUBJECTS/METHODS: In a cross-sectional study of 364 mothers of preschool children aged 3-5 years, these children's healthy eating behaviors were assessed using a validated preschool nutrition quotient (NQ-P) questionnaire. The children's overweight or obesity statuses were determined based on body mass index percentiles from the 2017 Korean National Growth Chart. The associations between the NQ-P score and risk of overweight or obesity were examined using multivariable logistic regression. The associations of individual, maternal, physical, and media environmental factors with the NQ-P score were also examined using multivariable linear regression. RESULTS: Preschool children with greater NQ-P scores were at a significantly lower risk of overweight or obesity (P < 0.01). The NQ-P score had a significantly positive association with maternal body mass index and an inverse association with household income (all P < 0.05). Maternal parenting and feeding practices exhibited associations with the NQ-P score. Positive associations were observed with "warm," "structured," and "autonomy-supportive" parenting as well as monitoring feeding practices (all P < 0.05). In addition, the NQ-P score had a significantly positive association with the childcare center's anti-obesogenic environment, such as the provision of nutritional and physical-activity support and vicinity of the built food environment to the home, including access to good-quality food, fruits and vegetables, and low-fat foods (all P < 0.05). Regarding media environments, the NQ-P score demonstrated more significant associations with viewing and eating and/or cooking content displayed on online video platforms (all P < 0.05) than with that on television. CONCLUSIONS: Our findings confirm the significance of healthy eating behaviors in early-childhood-obesity prevention and underscore the importance of multilevel maternal, physical, and media environmental interventions that effectively guide eating behaviors in preschool children.

석탄화력발전소 호흡성분진 작업환경 평가 전략 사례에 관한 연구 (A Study on Occupational Environment Assessment Strategies for Respirable Particulate Matter at Coal-Fired Power Plants )

  • 이은승;이윤근;신동일
    • 한국산업보건학회지
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    • 제33권3호
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    • pp.375-383
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    • 2023
  • Objectives: Coal-fired power plants feature diverse working conditions, including multi-layered employment structures and irregular work cycles due to outsourcing and non-standardized tasks. The current uniform occupational environment measurement systems have limitations in accurately assessing and evaluating these varied conditions. This study aims to propose alternative measurement and assessment strategies to supplement existing methods. Methods: Major domestic coal-fired power plants were selected as the study targets. To prepare for the study and establish strategies, work processes were identified and existing occupational environment measurement results were compared and analyzed. The study proceeded by employing three strategies: specific exposure groups (SEGs) measurement, continuous monitoring, and supplementary measurements, which were then compared and discussed. Results: Previous exposure index evaluations (5,268 cases) indicated that crystalline silica, a type of respirable particulate matter, had detection limits below the threshold (non-detectable) in 82.6% (4,349 cases) of instances. Exposures below 10% of the exposure limit were observed at a very low concentration of 96.1%. Similar exposure group measurements yielded results where detection limits were below the threshold in 38.2% of cases, and exposures below 10% of the limit were observed in 70.6%. Continuous monitoring indicated detection limits below the threshold in 12.6% of cases, and exposures below 10% of the limit were observed in 75.6%. Instances requiring active workplace management accounted for more than 30% of cases, with SEGs at 11.8% (four cases), showing a higher proportion compared to 3.0% (four cases) in continuous monitoring. For coal dust, exposures below 10% of the limit were highest in legal measurements at 90.2% (113 cases), followed by 74.0% (91 cases) in continuous monitoring, and 47.0% (16 cases) in SEGs. Instances exceeding 30% were most prevalent in SEGs at 14.7% (five cases), followed by legal measurements at 5.0% (eight cases), and continuous monitoring at 2.4% (three cases). When examining exposure levels through arithmetic means, crystalline silica was found to be 104.7% higher in SEGs at 0.0088 mg/m3 compared to 0.0043 mg/m3 in continuous monitoring. Coal dust measurements were highest in SEGs at 0.1247 mg/m3, followed by 0.1224 mg/m3 in legal measurements, and 0.0935 mg/m3 in continuous monitoring. Conclusions: Strategies involving SEGs measurement and continuous monitoring can enhance measurement reliability in environments with irregular work processes and frequent fluctuations in working conditions, as observed in coal-fired power plants. These strategies reduce the likelihood of omitting or underestimating processes and enhance measurement accuracy. In particular, a significant reduction in detection limits below the threshold for crystalline silica was observed. Supplementary measurements can identify worker exposure characteristics, uncover potential risks in blind spots of management, and provide a complementary method for legal measurements.

위성 레이더 영상 중 Sentinel-1을 활용한 탄소 흡수원 공간분석 - 운곡습지를 대상으로 - (Spatial Analysis of Carbon Storage in Satellite Radar Imagery Utilizing Sentinel-1: A Case Study of the Ungok Wetlands)

  • 유하은;조영일;이신우;이명진
    • 대한원격탐사학회지
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    • 제39권6_3호
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    • pp.1731-1745
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    • 2023
  • 2020년부터 시작된 신기후체제와 관련하여 파리협정 장기온도 목표를 위해 국가결정기여와 격년투명 보고서 제출이 요구된다. 기후변화에 관한 정부간 협의체에서 정의하는 토지이용·토지이용변화 및 임업에서 습지생태계는 탄소흡수원이나 국내 온실가스 인벤토리(Inventory) 산정에서 침수지로 지목 통계하여 배출원으로 보고되었다. 본 연구는 C-band 레이더 영상을 활용한 내륙 습지 토지이용 유형 세분화 및 변화량 산정을 진행하여 온실가스 인벤토리 산정 고도화에 기여하고자 한다. 연구지역은 국내 내륙습지 보전지역과 람사르(Ramsar) 습지로 지정된 운곡 습지이다. 활용 자료는 풍수기와 갈수기를 포함하는 24시기 Sentinel-1 위성 영상, 항공정사영상, 내륙습지 공간정보, 드론 촬영 영상이다. 이를 활용하여 침수지역과 비침수지역 구분, 침수지의 시계열적 공간 변화 정량화, 침수 지역의 최대·최소 면적을 차분한 변화 면적을 확인하였다. 변화 면적이 크게 산정된 지역을 대상으로 풍수기와 갈수기 두 시기 드론 촬영을 실시하였다. 습지의 침수지역 면적산출 및 시계열적 정량화는 국가 온실가스 인벤토리 고도화의 기초자료로 활용이 가능하다.

생성형 AI의 신뢰도에 대한 탐색적 연구 (An Exploratory Study on the Trustworthiness Analysis of Generative AI)

  • 김소연;조지연;이봉규
    • 인터넷정보학회논문지
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    • 제25권1호
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    • pp.79-90
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    • 2024
  • 본 연구는 대표적인 생성형 AI 기술인 ChatGPT의 이용자 신뢰를 중심으로 이용실태와 지속사용의도에 영향을 미치는 요인, 그리고 신뢰의 영향력이 목적에 따라 달라지는지를 탐색적으로 살펴보았다. 이를 위해 ChatGPT를 많이 이용하는 20대와 30대를 대상으로 설문조사를 실시하였으며 통계 패키지 프로그램인 IBM SPSS 27과 SmartPLS 4.0을 적용하여 분석을 수행하였다. Bhattacherjee의 기대충족모델(ECM)을 기반으로 구조방정식 모델을 구축하고, 경로분석과 다중그룹분석(MGA)를 실시하여 가설을 검증하였다. 본 연구의 결과는, 첫째, ChatGPT 이용자들은 일상적인 도구로 사용하기보다 특정 목적이나 필요에 따라 사용하고 있으며, 대부분의 사용자가 ChatGPT의 환각효과(Hallucination)에 대해 인지하고 있으나 이는 사용을 저해하는 요인은 아니었다. 둘째, 가설검정 결과 독립변수인기대충족, 인지된 유용성, 사용자 만족 요인 모두가 종속변수인 지속이용의도에 긍정적 영향을 미치고 있음을 확인하였다. 셋째, 이용자가 ChatGPT를 이용하는 목적에 따라 신뢰의 영향력이 달라짐이 확인되었다. 이용자가 정보 검색 목적으로 ChatGPT를 활용하는 경우에는 신뢰가 사용자 만족에 영향을 미친 반면, 창작 목적으로 사용하는 경우 영향을 미치지 않는 것으로 나타났다. 본 연구의 결과가 향후 사회와 기업에 있어 생성형 AI의 도입 과정에서 신뢰성의 문제를 해결하고 성공적인 도입을 위한 정책 수립 및 개선방안 도출을 위해 활용될 수 있기를 기대한다.