• Title/Summary/Keyword: Multi-center research

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Development and Verification of a Simultaneous Analytical Method for Whole Blood Metals and Metalloids for Biomonitoring Programs (바이오모니터링 프로그램을 위한 혈중 금속류 동시분석법 개발 및 확인 평가)

  • Cha, Sangwon;Oh, Eunha;Oh, Selim;Han, Sang Beom;Im, Hosub
    • Journal of Environmental Health Sciences
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    • v.47 no.1
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    • pp.64-77
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    • 2021
  • Objective: Biological monitoring of trace elements in human blood samples has become an important indicator of the health environment. The purpose of this study was to detect and evaluate multiple metal items in blood samples based on ICP-MS, to perform comparative evaluation with the existing analysis method, and to develop and verify a new method. Methods: 100 μL of whole blood from 80 healthy subjects was used to analyze ten metals (Sb, tAs, Cd, Pb, Mn, Hg, Mo, Ni, Se, Tl) using ICP-MS. Verification of the analysis method included calculation of linearity, accuracy, precision and detection limits. In addition, a comparative test with the conventional graphite furnace atomic absorption spectroscopy (GF-AAS) method was performed. In the case of Pb, Cd, and Hg in whole blood, cross-analysis between Pb, Cd, and Hg analysis methods was performed to confirm the difference between the existing method and the new method (ICP-MS). Results: The coefficient of determination (R2) was 0.999 or higher in seven items and 0.995 or higher in three items. The Pb result showed that Pearson's correlation coefficient was very high at 0.983, and the intraclass correlation coefficient was 0.966. The Cd result showed that Pearson's correlation coefficient was 0.917 between the existing method and the new analysis concentration value. Its intraclass correlation coefficient was 0.960, and there was no significant difference between the two groups. Hg had a low correlation at 0.687, and the intraclass correlation coefficient was 0.761, which was lower than that of Pb and Cd. The intra-day and inter-day accuracy of Pd and Cd were satisfactory, but Hg did not meet the criteria for both accuracy and precision when compared with the conventional analysis method. Conclusion: This study can be meaningful in that it proposes a more efficient and feasible analysis method by verifying a blood heavy metal concentration experiment using multiple simultaneous analyses. All samples were processed and analyzed using the new ICP-MS. It was confirmed that the agreement between the two methods was very high, with the agreement between the current and new methods being 0.769 to 0.998. This study proposes an efficient simultaneous methodology capable of analyzing multiple elements with small samples. In the future, studies of various applications and the reliability of ICP-MS analysis methods are required, and research on the verification of accurate, precise, and continuous analysis methods is required.

Structural Analysis of Multi-Functional Fishway in Seomoon Weir (서문보의 다기능 어도의 구조해석)

  • Lee, Young Jae;Lee, Jung Shin;Jang, Hyung Kyu
    • Ecology and Resilient Infrastructure
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    • v.7 no.4
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    • pp.308-319
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    • 2020
  • In this study, the field applicability of the recently constructed multifunctional fishway in Seomunbo, Yeongcheon-si, and Gyeongsangbuk-do were examined. The analysis variables were R/C slab (S1) and R/C+S/C slab (S2), the underground passage standard areas (width × length) were 1.4 m × 0.2 m, 1.4 m × 0.3 m, and 1.4 m × 0.6 m, and the flow velocities were 0.8, 1.2, and 1.6 m/s. As a result of the analysis, the safety of the design of Seomunbo was evaluated. The analysis showed compared to the Seomoon Weir fishway, the maximum stress of S2 decreased by 24 - 32%, the bending moment of the underground passage decreased by 16 - 33%, the maximum stress of the sidewall decreased by 20 - 36%. In addition, the bending moment of the upper slab decreased by 17 - 33%, the maximum stress of the upper slab decreased by 9 - 28%, and the bending moment decreased by 19 - 33%. Complementation was required in the following percentages: 18% and 14% for the maximum stress and bending moment of the underground passage, respectively, 15% and 17% for the maximum sidewall stress and bending moment, respectively, and 11% and 16% for the upper slab maximum stress and bending moment, respectively. The results showed that S2 was superior to that of the Seomoon Weir fishway, and the underground passage size of 1.4 m × 0.3 m was superior to those of 1.4 m × 0.2 m and 1.4 m × 0.6 m, and R/C+S/C slab was superior to that of R/C slab. The findings are expected to be useful for constructing and designing the multifunctional fishway.

Spawning Period Characteristics and Early Life History of the Eight Barbel Loach, Lefua costata (Pisces: Balitoridae) (쌀미꾸리(Lefua costata)의 산란기 특징 및 초기생활사)

  • Kim, Hyeong-Su;Han, Mee-Sook;Ko, Myeong-Hun
    • Korean Journal of Environment and Ecology
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    • v.35 no.3
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    • pp.285-293
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    • 2021
  • This study was conducted to elucidate spawning period characteristics and early life development of eight barbel loach, Lefua costata (Balitoridae) at the Jusucheon stream, Okgye-myeon, Gangneung-si, Gangwon-do, Korea between January and December in 2018. The spawning period was estimated to be from May to August, considering the change in the gonad-somatic index, the appearance of young fry, and frequency distribution in egg diameter. It was a multi-spawning type. The gender ratio was 1:0.79 with 1,117 females and 879 males collected. The egg size was 0.24-0.93 mm, with mature and immature eggs found during the spawning period. The size of mature eggs was 0.71±0.02 mm, and the average number of fecundity was 1,786±818 (n=31). Observation of the egg development showed that the fertilized eggs were the sticky, gray, segregated, and demersal type with 0.76±0.03 mm in diameter. The hatching of the embryos began at about 34 hours (hatching rate 50%) after fertilization underwater temperature of 25℃. The average length of the newly hatched pre-larvae was 2.7±0.11 mm. The average length of pre-larvae at 4 days after hatching was 4.5±0.16 mm, and the yolk sac was completely absorbed and entered the post-larvae stage. At 20 days after hatching, the average length of post-larvae was 11.5±0.67 mm, and their fin rays were formed before they transitioned to the juvenile stage. At 100 days after hatching, the average length reached 49.8±2.60 mm, and the appearance and the lateral sideband patterns were similar to those of the adult fish.

DNN-Based Dynamic Cell Selection and Transmit Power Allocation Scheme for Energy Efficiency Heterogeneous Mobile Communication Networks (이기종 이동통신 네트워크에서 에너지 효율화를 위한 DNN 기반 동적 셀 선택과 송신 전력 할당 기법)

  • Kim, Donghyeon;Lee, In-Ho
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.26 no.10
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    • pp.1517-1524
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    • 2022
  • In this paper, we consider a heterogeneous network (HetNet) consisting of one macro base station and multiple small base stations, and assume the coordinated multi-point transmission between the base stations. In addition, we assume that the channel between the base station and the user consists of path loss and Rayleigh fading. Under these assumptions, we present the energy efficiency (EE) achievable by the user for a given base station and we formulate an optimization problem of dynamic cell selection and transmit power allocation to maximize the total EE of the HetNet. In this paper, we propose an unsupervised deep learning method to solve the optimization problem. The proposed deep learning-based scheme can provide high EE while having low complexity compared to the conventional iterative convergence methods. Through the simulation, we show that the proposed dynamic cell selection scheme provides higher EE performance than the maximum signal-to-interference-plus-noise ratio scheme and the Lagrangian dual decomposition scheme, and the proposed transmit power allocation scheme provides the similar performance to the trust region interior point method which can achieve the maximum EE.

A Study on the Development of Driving Risk Assessment Model for Autonomous Vehicles Using Fuzzy-AHP (퍼지 AHP를 이용한 자율주행차량의 운행 위험도 평가 모델 개발 연구)

  • Siwon Kim;Jaekyung Kwon;Jaeseong Hwang;Sangsoo Lee;Choul ki Lee
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.22 no.1
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    • pp.192-207
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    • 2023
  • Commercialization of level-4 (Lv.4) autonomous driving applications requires the definition of a safe road environment under which autonomous vehicles can operate safely. Thus, a risk assessment model is required to determine whether the operation of autonomous vehicles can provide safety to is sufficiently prepared for future real-life traffic problems. Although the risk factors of autonomous vehicles were selected and graded, the decision-making method was applied as qualitative data using a survey of experts in the field of autonomous driving due to the cause of the accident and difficulty in obtaining autonomous driving data. The fuzzy linguistic representation of decision-makers and the fuzzy analytic hierarchy process (AHP), which converts uncertainty into quantitative figures, were implemented to compensate for the AHP shortcomings of the multi-standard decision-making technique. Through the process of deriving the weights of the upper and lower attributes, the road alignment, which is a physical infrastructure, was analyzed as the most important risk factor in the operation risk of autonomous vehicles. In addition, the operation risk of autonomous vehicles was derived through the example of the risk of operating autonomous vehicles for the 5 areas to be evaluated.

The Reconstruction of Life Story of Koryo-saram Min Tatyana (고려인 민 타찌아나의 생애 이야기 재구성)

  • Yun, Heejin;Kim, Youngsoon;Aigozhayeva, Aigerim;Bekboeva, Aigul
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.6 no.10
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    • pp.449-456
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    • 2016
  • In this study we recomposed the life story of Min Tatyana who is a Koryo-saram, or in other words, an ethnic Korean residing Kazakhstan. The life story of an overseas Korean, or Koryo-saram to be exact, includes in itself their multi-level identity which consists of the period of the immigration of Koryo-sarams, the special incident of deportation, as well as life as people of the Soviet Union and Kazakhstan, and life as a Korean race. In this study, we were confirmed the texture of the Korean race thought ordinary korean Min Tatyana life who living in Kazakhstan. The life story of Min Tatyana was reconstituted into two stories as "growing up in a multicultural society as Koryo-Saram" and "to live a life as the descendants of independence activist". She was born in historically region Kyzylorda, where living Korean groups and now she is living in Almaty, where living the many koreans ethnic groups of Kazakhstan. Also, her parents were respected to the local residents and her grandfather of husband was famous independent activist. These aspects have helped keep her Korean ethnic identity. The life story of Min Tatyana is personal story and qualitative text, which shows social, cultural background of korean ethnic who living in Kazakhstan. This study is expected to help to confirm the Koryo-Saram characteristics and aspect of their multilayer life.

Early childhood eating behaviors associated with risk of overweight and its socio-ecological determinants in Korean preschool children

  • Yeri Kim ;Jiye Kim ;Bomi Lee ;Seungyoun Jung;Seo-Jin Chung ;Hyekyeong Kim ;Nana Shin ;Yuri Kim
    • Nutrition Research and Practice
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    • v.17 no.4
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    • pp.717-734
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    • 2023
  • BACKGROUND/OBJECTIVES: This study aimed to identify preschool children's eating behaviors associated with early childhood obesity and its multi-level, socio-ecological determinants. SUBJECTS/METHODS: In a cross-sectional study of 364 mothers of preschool children aged 3-5 years, these children's healthy eating behaviors were assessed using a validated preschool nutrition quotient (NQ-P) questionnaire. The children's overweight or obesity statuses were determined based on body mass index percentiles from the 2017 Korean National Growth Chart. The associations between the NQ-P score and risk of overweight or obesity were examined using multivariable logistic regression. The associations of individual, maternal, physical, and media environmental factors with the NQ-P score were also examined using multivariable linear regression. RESULTS: Preschool children with greater NQ-P scores were at a significantly lower risk of overweight or obesity (P < 0.01). The NQ-P score had a significantly positive association with maternal body mass index and an inverse association with household income (all P < 0.05). Maternal parenting and feeding practices exhibited associations with the NQ-P score. Positive associations were observed with "warm," "structured," and "autonomy-supportive" parenting as well as monitoring feeding practices (all P < 0.05). In addition, the NQ-P score had a significantly positive association with the childcare center's anti-obesogenic environment, such as the provision of nutritional and physical-activity support and vicinity of the built food environment to the home, including access to good-quality food, fruits and vegetables, and low-fat foods (all P < 0.05). Regarding media environments, the NQ-P score demonstrated more significant associations with viewing and eating and/or cooking content displayed on online video platforms (all P < 0.05) than with that on television. CONCLUSIONS: Our findings confirm the significance of healthy eating behaviors in early-childhood-obesity prevention and underscore the importance of multilevel maternal, physical, and media environmental interventions that effectively guide eating behaviors in preschool children.

Comparative analysis of ONE parameter hydrological model on domestic watershed (ONE 모형의 국내유역 적용 및 비교 분석)

  • Ko, Heemin;An, Hyunuk;Noh, Jaekyung;Lee, Seungjun
    • Journal of Korea Water Resources Association
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    • v.57 no.1
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    • pp.59-72
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    • 2024
  • Agricultural reservoirs supply water for various purposes such as irrigation, maintenance, and living. Since agricultural reservoirs respond sensitively to seasonal and climate changes, it is essential to estimate supply and inflow for efficient operation, and water management should be done based on these data. However, in the case of agricultural reservoirs, the measurement of supply and inflow is relatively insufficient compared to multi-purpose dams, and inflow-supply analysis in agricultural reservoirs through water balance analysis is necessary for efficient water management. Therefore, rainfall-runoff analysis models such as ONE model and Tank model have been developed and used for reservoir water balance analysis, but the applicability analysis for ungauged watersheds is insufficient. The ONE model is designed for daily runoff calculation, and the model has one parameter, which is advantageous for calibration and ungauged watershed analysis. In this study, the water balance was analyzed through the ONE model and the Tank model for 15 watersheds upstream of dams, and R2 and NSE were used to quantitatively compare the performance of the two models. The simulation results show that the ONE model is suitable for predicting the inflow of agricultural reservoirs with the ungauged watershed

Carbon nanotube field emission display

  • Chil, Won-Bong;Kim, Jong-Min
    • Electrical & Electronic Materials
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    • v.12 no.7
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    • pp.7-11
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    • 1999
  • Fully sealed field emission display in size of 4.5 inch has been fabricated using single-wall carbon nanotubes-organic vehicle com-posite. The fabricated display were fully scalable at low temperature below 415$^{\circ}C$ and CNTs were vertically aligned using paste squeeze and surface rubbing techniques. The turn-on fields of 1V/${\mu}{\textrm}{m}$ and field emis-sion current of 1.5mA at 3V/${\mu}{\textrm}{m}$ (J=90${\mu}{\textrm}{m}$/$\textrm{cm}^2$)were observed. Brightness of 1800cd/$m^2$ at 3.7V/${\mu}{\textrm}{m}$ was observed on the entire area of 4.5-inch panel from the green phosphor-ITO glass. The fluctuation of the current was found to be about 7% over a 4.5-inch cath-ode area. This reliable result enables us to produce large area full-color flat panel dis-play in the near future. Carbon nanotubes (CNTs) have attracted much attention because of their unique elec-trical properties and their potential applica-tions [1, 2]. Large aspect ratio of CNTs together with high chemical stability. ther-mal conductivity, and high mechanical strength are advantageous for applications to the field emitter [3]. Several results have been reported on the field emissions from multi-walled nanotubes (MWNTs) and single-walled nanotubes (SWNTs) grown from arc discharge [4, 5]. De Heer et al. have reported the field emission from nan-otubes aligned by the suspension-filtering method. This approach is too difficult to be fully adopted in integration process. Recently, there have been efforts to make applications to field emission devices using nanotubes. Saito et al. demonstrated a car-bon nanotube-based lamp, which was oper-ated at high voltage (10KV) [8]. Aproto-type diode structure was tested by the size of 100mm $\times$ 10mm in vacuum chamber [9]. the difficulties arise from the arrangement of vertically aligned nanotubes after the growth. Recently vertically aligned carbon nanotubes have been synthesized using plasma-enhanced chemical vapor deposition(CVD) [6, 7]. Yet, control of a large area synthesis is still not easily accessible with such approaches. Here we report integra-tion processes of fully sealed 4.5-inch CNT-field emission displays (FEDs). Low turn-on voltage with high brightness, and stabili-ty clearly demonstrate the potential applica-bility of carbon nanotubes to full color dis-plays in near future. For flat panel display in a large area, car-bon nanotubes-based field emitters were fabricated by using nanotubes-organic vehi-cles. The purified SWNTs, which were syn-thesized by dc arc discharge, were dispersed in iso propyl alcohol, and then mixed with on organic binder. The paste of well-dis-persed carbon nanotubes was squeezed onto the metal-patterned sodalime glass throuhg the metal mesh of 20${\mu}{\textrm}{m}$ in size and subse-quently heat-treated in order to remove the organic binder. The insulating spacers in thickness of 200${\mu}{\textrm}{m}$ are inserted between the lower and upper glasses. The Y\ulcornerO\ulcornerS:Eu, ZnS:Cu, Al, and ZnS:Ag, Cl, phosphors are electrically deposited on the upper glass for red, green, and blue colors, respectively. The typical sizes of each phosphor are 2~3 micron. The assembled structure was sealed in an atmosphere of highly purified Ar gas by means of a glass frit. The display plate was evacuated down to the pressure level of 1$\times$10\ulcorner Torr. Three non-evaporable getters of Ti-Zr-V-Fe were activated during the final heat-exhausting procedure. Finally, the active area of 4.5-inch panel with fully sealed carbon nanotubes was pro-duced. Emission currents were character-ized by the DC-mode and pulse-modulating mode at the voltage up to 800 volts. The brightness of field emission was measured by the Luminance calorimeter (BM-7, Topcon).

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Evaluation of Land Use Change Impact on Hydrology and Water Quality Health in Geum River Basin (금강유역의 토지이용 변화가 수문·수질 건전성에 미치는 영향 평가)

  • LEE, Ji-Wan;PARK, Jong-Yoon;JUNG, Chung-Gil;KIM, Seong-Joon
    • Journal of the Korean Association of Geographic Information Studies
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    • v.22 no.2
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    • pp.82-96
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    • 2019
  • This study evaluated the status of watershed health in Geum River Basin by SWAT (Soil and Water Assessment Tool) hydrology and water quality. The watershed healthiness from watershed hydrology and stream water quality was calculated using multivariate normal distribution from 0(poor) to 1(good). Before evaluation of watershed healthiness, the SWAT calibration for 11 years(2005~2015) of streamflow(Q) at 5 locations with 0.50~0.77 average Nash-Sutcliffe model efficiency and suspended solid (SS), total nitrogen(T-N), and total phosphorus(T-P) at 3 locations with 0.67~0.94, 0.59~0.79, and 0.61~0.79 determination coefficient($R^2$) respectively. For 24 years (1985~2008) the spatiotemporal change of watershed healthiness was analyzed with calibarted SWAT and 5 land use data of 1985, 1990, 1995, 2000, and 2008. The 2008 SWAT results showed that the surface runoff increased by 40.6%, soil moisture and baseflow decreased by 6.8% and 3.0% respectively compared to 1985 reference year. The stream water quality of SS, T-N, and T-P increased by 29.2%, 9.3%, and 16.7% respectively by land development and agricultural activity. Based on the 1985 year land use condition. the 2008 watershed healthiness of hydrology and stream water quality decreased from 1 to 0.94 and 0.69 respectively. The results of this study be able to detect changes in watershed environment due to human activity compared to past natural conditions.